Gene Card 基因详情

支持统一新 ID、NCBI Gene ID、GeneID、locus_tag、Transcript ID、Protein ID，以及已人工核对的文献基因名查询。页面会先解析到丹参统一基因，再整合坐标、序列、注释、亚细胞定位、EMS 突变和下载入口。

当前解析结果

`SmilChr04G003587`

染色体: Chr04 坐标: 52298267-52302894 链方向: - 类型: protein_coding

基本信息

统一新 Gene ID	`SmilChr04G003587`
名称	SmilChr04G003587
描述	E3 ubiquitin-protein ligase RHF2A-like
染色体 / SeqID	Chr04 / NC_080390.1
坐标与链方向	52298267 - 52302894 / `-`

ID 对照

NCBI Gene ID	`LOC131020462`
GeneID	`131020462`
locus_tag	`-`
NCBI Name	`LOC131020462`
原始查询	`SmilChr04G003587`

查看完整 ID 对照表

功能注释

来源	GFF basic annotation; NCBI GO GAF; Pfam-A/HMMER; Arabidopsis/Rice homolog
描述	E3 ubiquitin-protein ligase RHF2A-like
产物	E3 ubiquitin-protein ligase RHF2A-like
Arabidopsis	`AT5G22000` (RHF2A) RING-H2 group F2A [Source:NCBI gene (formerly Entrezgene);Acc:832260] identity=58.2; qcov=0.952; evalue=3.64e-137; confidence=high
Rice	`Os11g0572500` (OsRFP) - identity=56.1; qcov=1.03; evalue=1.78e-139; confidence=high
GO	GO:0004842 (ubiquitin-protein transferase activity)
KEGG	-
Pfam	PF00097 (zf-C3HC4); PF12678 (zf-rbx1); PF12861 (zf-ANAPC11); PF13445 (zf-RING_UBOX); PF13639 (zf-RING_2); PF13923 (zf-C3HC4_2); PF17123 (zf-RING_11)
InterPro	-
eggNOG	-
NR	GeneID:131020462

打开注释模块

亚细胞定位 Top 5

Rank	定位位置	中文	Score	Protein ID
1	Cytoplasm	细胞质	1.00000	`XP_057805259.1`
2	Cytosol	细胞质基质	1.00000	`XP_057805259.1`
3	Endoplasmic reticulum	内质网	0.20000	`XP_057805259.1`
4	Nucleus	细胞核	0.00000	`XP_057805259.1`
5	Chromosome	染色体	0.00000	`XP_057805259.1`

进入亚细胞定位查询

EMS 诱变突变

下表显示该基因在丹参 EMS 材料中的前 12 个候选突变；完整结果可进入 EMS 突变库继续筛选或下载。

位置	REF	ALT	类型	影响	携带材料数	材料
`Chr4:52299240`	`G`	`A`	EMS_canonical_SNV	CDS_variant	3	B28,B76,C16
`Chr4:52299425`	`C`	`T`	EMS_canonical_SNV	CDS_variant	1	B27
`Chr4:52299474`	`C`	`T`	EMS_canonical_SNV	CDS_variant	1	B138
`Chr4:52299480`	`T`	`TAC`	2bp_insertion	frameshift_variant	5	B136,B27,B91,C4,D2
`Chr4:52299480`	`T`	`TAC`	2bp_insertion	CDS_variant	5	B136,B27,B91,C4,D2
`Chr4:52299482`	`CCT`	`C`	2bp_deletion	frameshift_variant	6	B120,B136,B27,B91,C4,D2
`Chr4:52299490`	`C`	`T`	EMS_canonical_SNV	CDS_variant	5	B136,B27,B91,C4,D2

进入 EMS 突变库

预测功能结构域

结构域结果来自 Pfam-A HMM 数据库和 HMMER hmmscan；位置为对应蛋白序列上的氨基酸坐标。

XP_057805259.1

373 aa

186

373

zf-rbx1

zf-ANAPC11

zf-RING_2

zf-RING_11

zf-RING_UBOX

zf-C3HC4

zf-C3HC4_2

PF12678 zf-rbx1 31-77 aa PF12861 zf-ANAPC11 34-84 aa PF13639 zf-RING_2 36-77 aa PF17123 zf-RING_11 37-64 aa PF13445 zf-RING_UBOX 37-75 aa PF00097 zf-C3HC4 37-77 aa PF13923 zf-C3HC4_2 37-77 aa

XP_057805260.1

372 aa

186

372

zf-rbx1

zf-ANAPC11

zf-RING_2

zf-RING_11

zf-RING_UBOX

zf-C3HC4

zf-C3HC4_2

Protein ID	来源	结构域编号	结构域名称	类型	起始 aa	终止 aa	E-value	Score	说明
`XP_057805259.1`	Pfam	`PF12678`	zf-rbx1	Domain	31	77	8.2e-09	36.3	RING-H2 zinc finger domain
`XP_057805259.1`	Pfam	`PF12861`	zf-ANAPC11	Domain	34	84	1.3e-06	29.1	Anaphase-promoting complex subunit 11 RING-H2 finger
`XP_057805259.1`	Pfam	`PF13639`	zf-RING_2	Domain	36	77	6.2e-11	43.1	Ring finger domain
`XP_057805259.1`	Pfam	`PF17123`	zf-RING_11	Domain	37	64	9.4e-09	35.5	RING-like zinc finger
`XP_057805259.1`	Pfam	`PF13445`	zf-RING_UBOX	Domain	37	75	1.3e-06	29.0	RING-type zinc-finger
`XP_057805259.1`	Pfam	`PF00097`	zf-C3HC4	Domain	37	77	2.6e-07	31.1	Zinc finger, C3HC4 type (RING finger)
`XP_057805259.1`	Pfam	`PF13923`	zf-C3HC4_2	Domain	37	77	4.9e-08	33.4	Zinc finger, C3HC4 type (RING finger)
`XP_057805260.1`	Pfam	`PF12678`	zf-rbx1	Domain	31	77	8.1e-09	36.3	RING-H2 zinc finger domain
`XP_057805260.1`	Pfam	`PF12861`	zf-ANAPC11	Domain	34	84	1.3e-06	29.1	Anaphase-promoting complex subunit 11 RING-H2 finger
`XP_057805260.1`	Pfam	`PF13639`	zf-RING_2	Domain	36	77	6.1e-11	43.1	Ring finger domain
`XP_057805260.1`	Pfam	`PF17123`	zf-RING_11	Domain	37	64	9.3e-09	35.5	RING-like zinc finger
`XP_057805260.1`	Pfam	`PF13445`	zf-RING_UBOX	Domain	37	75	1.3e-06	29.0	RING-type zinc-finger
`XP_057805260.1`	Pfam	`PF00097`	zf-C3HC4	Domain	37	77	2.6e-07	31.1	Zinc finger, C3HC4 type (RING finger)
`XP_057805260.1`	Pfam	`PF13923`	zf-C3HC4_2	Domain	37	77	4.9e-08	33.4	Zinc finger, C3HC4 type (RING finger)

cDNA / CDS / Protein 序列

下载基因组 DNA（仅基因区域）

每个公开基因均提供参考注释对应的转录本序列；蛋白编码基因另提供 CDS 和蛋白序列。非编码 RNA 不适用 CDS 或蛋白下载。真实 accession 的版本后缀予以保留。

cDNA

4 records

下载 cDNA FASTA

XR_009100710.1
TTATTGAATTTGCCGAAAAAGTACTGGATTTGCACCACCAAATCCAAACCCACCACTCATACTCATACATCACGTTTAATTTAATATTTTCCCCTCTCTGCGTTTAATAATTTAATGTCTTAATAAATATACGATTGCGTGACCTCCATATCTATTTCCTGCTTTTCACACCTCTCCGTTTCTCTCTCCTCCCTTTCTCTCTCTCTCTCGAAATTGCGTGAGGTTTCCGTGAATGTGACCTCTGCGTTAATTTTCATATT...

XR_009100709.1
TTATTGAATTTGCCGAAAAAGTACTGGATTTGCACCACCAAATCCAAACCCACCACTCATACTCATACATCACGTTTAATTTAATATTTTCCCCTCTCTGCGTTTAATAATTTAATGTCTTAATAAATATACGATTGCGTGACCTCCATATCTATTTCCTGCTTTTCACACCTCTCCGTTTCTCTCTCCTCCCTTTCTCTCTCTCTCTCGAAATTGCGTGAGGTTTCCGTGAATGTGACCTCTGCGTTAATTTTCATATT...

CDS

2 records

下载 CDS FASTA

LOC131020462
ATGGAGGGTAAAGTTCCGGGGATGGATGAGGCCAAGAAGGCAGAGACTCACATGACATCAGCTGCGGCTTTTGTCGAGGGAGGGATACAGGAGTCTTGTGATGATGCTTGTAGCATATGCCTCGAGGGGTTTAGTGATAGCGATCCTATGACGGTGACAAGTTGCAAGCATGAGTTCCACCTTCAGTGCATTCTTGAATGGTGCCAAAGAAGCTCCAATTGTCCAATGTGCTGGCAAAGTATTAGTCTGAAGGATCCTGC...

Protein

2 records

下载 Protein FASTA

XP_057805259.1
MEGKVPGMDEAKKAETHMTSAAAFVEGGIQESCDDACSICLEGFSDSDPMTVTSCKHEFHLQCILEWCQRSSNCPMCWQSISLKDPANQELLEAVERERSIRLTPSRNATIFRHPTLGDFELQHLPAGINDAELQERIIQHLATAAAMGRTHRIARREGSRSRSSAHTRPQFVVFSGHPPGSSAGSGGEEIEPIAAAENNPSVPVTTVNNIGSNQNSASSSRPLVVPTSGQGSSNDNRSYTSQSSLPNQDRAGPSELQSI...

XP_057805260.1
MEGKVPGMDEAKKAETHMTSAAAFVEGGIQESCDDACSICLEGFSDSDPMTVTSCKHEFHLQCILEWCQRSSNCPMCWQSISLKDPANQELLEAVERERSIRLTPSRNATIFRHPTLGDFELQHLPAGINDAELQERIIQHLATAAAMGRTHRIARREGSRSRSSAHTRPQFVVFSGHPPGSSAGSGGEEIEPIAAAENNPSVPVTTVNNIGSNQNSASSSRPLVVPTSGQGSSNDNSYTSQSSLPNQDRAGPSELQSIS...

上下游序列下载

upstream/downstream 最大各 10000 bp。负链基因会自动反向互补，使最终 FASTA 为转录方向 5′→3′。

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