Gene Card 基因详情

支持统一新 ID、NCBI Gene ID、GeneID、locus_tag、Transcript ID、Protein ID，以及已人工核对的文献基因名查询。页面会先解析到丹参统一基因，再整合坐标、序列、注释、亚细胞定位、EMS 突变和下载入口。

当前解析结果

`SmilChr04G003715`

染色体: Chr04 坐标: 53438018-53448034 链方向: - 类型: protein_coding

基本信息

统一新 Gene ID	`SmilChr04G003715`
名称	SmilChr04G003715
描述	DNA-directed RNA polymerase II subunit RPB1-like
染色体 / SeqID	Chr04 / NC_080390.1
坐标与链方向	53438018 - 53448034 / `-`

ID 对照

NCBI Gene ID	`LOC131020589`
GeneID	`131020589`
locus_tag	`-`
NCBI Name	`LOC131020589`
原始查询	`SmilChr04G003715`

查看完整 ID 对照表

功能注释

来源	GFF basic annotation; NCBI GO GAF; KEGG smil; Pfam-A/HMMER; Arabidopsis/Rice homolog
描述	DNA-directed RNA polymerase II subunit RPB1-like
产物	DNA-directed RNA polymerase II subunit RPB1-like
Arabidopsis	`AT4G35800` (NRPB1) RNA polymerase II large subunit [Source:NCBI gene (formerly Entrezgene);Acc:829734] identity=81.3; qcov=0.997; evalue=0; confidence=high
Rice	`Os05g0151000` - identity=81; qcov=0.949; evalue=0; confidence=high
GO	GO:0001055 (GO:0001055); GO:0003677 (DNA binding); GO:0005665 (RNA polymerase II, core complex); GO:0006366 (transcription by RNA polymerase II)
KEGG	smil03020 (RNA polymerase - Salvia miltiorrhiza (redroot sage)); smil03420 (Nucleotide excision repair - Salvia miltiorrhiza (redroot sage))
Pfam	PF00623 (RNA_pol_Rpb1_2); PF04983 (RNA_pol_Rpb1_3); PF04990 (RNA_pol_Rpb1_7); PF04992 (RNA_pol_Rpb1_6); PF04997 (RNA_pol_Rpb1_1); PF04998 (RNA_pol_Rpb1_5); PF05000 (RNA_pol_Rpb1_4); PF05001 (RNA_pol_Rpb1_R)
InterPro	-
eggNOG	-
NR	GeneID:131020589

打开注释模块

亚细胞定位 Top 5

Rank	定位位置	中文	Score	Protein ID
1	Nucleus	细胞核	1.00000	`XP_057805487.1`
2	Nucleoplasm	核质	1.00000	`XP_057805487.1`
3	Chromosome	染色体	0.40000	`XP_057805487.1`
4	Chromatin	染色质	0.40000	`XP_057805487.1`
5	Nucleolar fibrillar center	Nucleolar fibrillar center	0.40000	`XP_057805487.1`

进入亚细胞定位查询

EMS 诱变突变

下表显示该基因在丹参 EMS 材料中的前 12 个候选突变；完整结果可进入 EMS 突变库继续筛选或下载。

位置	REF	ALT	类型	影响	携带材料数	材料
`Chr4:53440390`	`C`	`T`	EMS_canonical_SNV	CDS_variant	1	B11
`Chr4:53440399`	`G`	`A`	EMS_canonical_SNV	CDS_variant	1	B11
`Chr4:53440435`	`G`	`A`	EMS_canonical_SNV	CDS_variant	5	B128,B29,C64,C66,C71
`Chr4:53440526`	`G`	`A`	EMS_canonical_SNV	CDS_variant	3	B49,B79,D3
`Chr4:53440537`	`G`	`A`	EMS_canonical_SNV	CDS_variant	1	C70
`Chr4:53440709`	`C`	`T`	EMS_canonical_SNV	CDS_variant	5	B105,B91,C29,C59,D7
`Chr4:53440748`	`G`	`A`	EMS_canonical_SNV	CDS_variant	1	B105
`Chr4:53440809`	`G`	`A`	EMS_canonical_SNV	CDS_variant	1	D8
`Chr4:53440913`	`C`	`T`	EMS_canonical_SNV	CDS_variant	2	B41,D11
`Chr4:53440931`	`C`	`T`	EMS_canonical_SNV	CDS_variant	4	A23,B106,B67,B77
`Chr4:53441198`	`G`	`A`	EMS_canonical_SNV	CDS_variant	5	B34,B91,C50,C54,C57
`Chr4:53441273`	`G`	`A`	EMS_canonical_SNV	CDS_variant	3	B120,B34,C33

进入 EMS 突变库

预测功能结构域

结构域结果来自 Pfam-A HMM 数据库和 HMMER hmmscan；位置为对应蛋白序列上的氨基酸坐标。

XP_057805487.1

1833 aa

916

1833

RNA_pol_Rpb1_1

RNA_pol_Rpb1_2

RNA_pol_Rpb1_3

RNA_pol_Rpb1_4

RNA_pol_Rpb1_5

RNA_pol_Rpb1_6

RNA_pol_Rpb1_7

RNA_pol_Rpb1_R

PF04997 RNA_pol_Rpb1_1 14-350 aa PF00623 RNA_pol_Rpb1_2 352-520 aa PF04983 RNA_pol_Rpb1_3 523-687 aa PF05000 RNA_pol_Rpb1_4 714-818 aa PF04998 RNA_pol_Rpb1_5 825-1415 aa PF04992 RNA_pol_Rpb1_6 891-1075 aa PF04990 RNA_pol_Rpb1_7 1160-1294 aa PF05001 RNA_pol_Rpb1_R 1552-1565 aa PF05001 RNA_pol_Rpb1_R 1566-1579 aa PF05001 RNA_pol_Rpb1_R 1580-1593 aa PF05001 RNA_pol_Rpb1_R 1594-1607 aa PF05001 RNA_pol_Rpb1_R 1608-1621 aa PF05001 RNA_pol_Rpb1_R 1622-1635 aa PF05001 RNA_pol_Rpb1_R 1636-1649 aa PF05001 RNA_pol_Rpb1_R 1650-1663 aa PF05001 RNA_pol_Rpb1_R 1664-1677 aa PF05001 RNA_pol_Rpb1_R 1678-1691 aa PF05001 RNA_pol_Rpb1_R 1692-1705 aa PF05001 RNA_pol_Rpb1_R 1706-1719 aa

Protein ID	来源	结构域编号	结构域名称	类型	起始 aa	终止 aa	E-value	Score	说明
`XP_057805487.1`	Pfam	`PF04997`	RNA_pol_Rpb1_1	Domain	14	350	5.5e-116	388.0	RNA polymerase Rpb1, domain 1
`XP_057805487.1`	Pfam	`PF00623`	RNA_pol_Rpb1_2	Domain	352	520	8.3e-72	241.6	RNA polymerase Rpb1, domain 2
`XP_057805487.1`	Pfam	`PF04983`	RNA_pol_Rpb1_3	Domain	523	687	1.2e-51	175.5	RNA polymerase Rpb1, domain 3
`XP_057805487.1`	Pfam	`PF05000`	RNA_pol_Rpb1_4	Domain	714	818	1.9e-39	134.6	RNA polymerase Rpb1, domain 4
`XP_057805487.1`	Pfam	`PF04998`	RNA_pol_Rpb1_5	Domain	825	1415	6.2e-104	347.9	RNA polymerase Rpb1, domain 5
`XP_057805487.1`	Pfam	`PF04992`	RNA_pol_Rpb1_6	Domain	891	1075	1.6e-65	221.2	RNA polymerase Rpb1, domain 6
`XP_057805487.1`	Pfam	`PF04990`	RNA_pol_Rpb1_7	Domain	1160	1294	1.9e-53	180.9	RNA polymerase Rpb1, domain 7
`XP_057805487.1`	Pfam	`PF05001`	RNA_pol_Rpb1_R	Repeat	1552	1565	1.3e-16	60.5	RNA polymerase Rpb1 C-terminal repeat
`XP_057805487.1`	Pfam	`PF05001`	RNA_pol_Rpb1_R	Repeat	1566	1579	1.3e-16	60.5	RNA polymerase Rpb1 C-terminal repeat
`XP_057805487.1`	Pfam	`PF05001`	RNA_pol_Rpb1_R	Repeat	1580	1593	1.3e-16	60.5	RNA polymerase Rpb1 C-terminal repeat
`XP_057805487.1`	Pfam	`PF05001`	RNA_pol_Rpb1_R	Repeat	1594	1607	1.3e-16	60.5	RNA polymerase Rpb1 C-terminal repeat
`XP_057805487.1`	Pfam	`PF05001`	RNA_pol_Rpb1_R	Repeat	1608	1621	1.3e-16	60.5	RNA polymerase Rpb1 C-terminal repeat
`XP_057805487.1`	Pfam	`PF05001`	RNA_pol_Rpb1_R	Repeat	1622	1635	1.3e-16	60.5	RNA polymerase Rpb1 C-terminal repeat
`XP_057805487.1`	Pfam	`PF05001`	RNA_pol_Rpb1_R	Repeat	1636	1649	1.3e-16	60.5	RNA polymerase Rpb1 C-terminal repeat
`XP_057805487.1`	Pfam	`PF05001`	RNA_pol_Rpb1_R	Repeat	1650	1663	1.3e-16	60.5	RNA polymerase Rpb1 C-terminal repeat
`XP_057805487.1`	Pfam	`PF05001`	RNA_pol_Rpb1_R	Repeat	1664	1677	1.3e-16	60.5	RNA polymerase Rpb1 C-terminal repeat
`XP_057805487.1`	Pfam	`PF05001`	RNA_pol_Rpb1_R	Repeat	1678	1691	1.3e-16	60.5	RNA polymerase Rpb1 C-terminal repeat
`XP_057805487.1`	Pfam	`PF05001`	RNA_pol_Rpb1_R	Repeat	1692	1705	1.3e-16	60.5	RNA polymerase Rpb1 C-terminal repeat
`XP_057805487.1`	Pfam	`PF05001`	RNA_pol_Rpb1_R	Repeat	1706	1719	1.3e-16	60.5	RNA polymerase Rpb1 C-terminal repeat

cDNA / CDS / Protein 序列

下载基因组 DNA（仅基因区域）

每个公开基因均提供参考注释对应的转录本序列；蛋白编码基因另提供 CDS 和蛋白序列。非编码 RNA 不适用 CDS 或蛋白下载。真实 accession 的版本后缀予以保留。

cDNA

1 records

下载 cDNA FASTA

XM_057949504.1
CCCTCATTCTCTTCTTTGGTCTCAAAGCCGCCTCTCCTCCTTCAGAGAAGAGCGCAGCGTGAAAAAAGTTTTCTTCAGAAACCCCAAAAATCAGTTACTTAACAGAAACCGCGAATAATTTGAAGTACTTGAAAACCATATTTGTTTCTAATTTTGGAATTATTATATATCAGCTAGCATAATAAATCATAATCGAAAACCCTAGGGTAGAATCTCCGGTGTCGCAATGGATCTGCGGTTCCCCTTCTCGCCGGCAGAGG...

CDS

1 records

下载 CDS FASTA

LOC131020589
ATGGATCTGCGGTTCCCCTTCTCGCCGGCAGAGGTCGCGAAAGTCCGCGTCGTCCAATTCGGCATTCTCAGCCCCGATGAGATCAGACAAATGTCTGTTGTGCATATAGAGCACAGCGAGACGACGGAAAGAGGCAAGCCGAAGATCGGTGGTTTGAGCGACCCGCGTCTGGGGACGATTGATCGGAAGATGAAGTGCGAGACTTGTATGGCGAACATGGCTGACTGCCCCGGTCACTTCGGTCACCTTGAGCTCGCCAA...

Protein

1 records

下载 Protein FASTA

XP_057805487.1
MDLRFPFSPAEVAKVRVVQFGILSPDEIRQMSVVHIEHSETTERGKPKIGGLSDPRLGTIDRKMKCETCMANMADCPGHFGHLELAKPMFHIGFMKTVLSILRSVCFNCSKILADEDDPKFKQAMRIRNPKNRLKKILDACKNKSKCEGGDEIDVRGQDSEEPVKKSRGGCGAQQPKISIDGMKMVAEYKIQKKKSDDQDQMPEPVERKQLLSAEKVLSILKRITDEDCQLLGLNPKYARPDWMILQVLPIPPPPVRPSV...

上下游序列下载

upstream/downstream 最大各 10000 bp。负链基因会自动反向互补，使最终 FASTA 为转录方向 5′→3′。

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