Gene Card 基因详情

支持统一新 ID、NCBI Gene ID、GeneID、locus_tag、Transcript ID、Protein ID，以及已人工核对的文献基因名查询。页面会先解析到丹参统一基因，再整合坐标、序列、注释、亚细胞定位、EMS 突变和下载入口。

当前解析结果

`SmilChr04G003774`

染色体: Chr04 坐标: 53934312-53937175 链方向: + 类型: protein_coding

基本信息

统一新 Gene ID	`SmilChr04G003774`
名称	SmilChr04G003774
描述	protein BRI1-5 ENHANCED 1-like
染色体 / SeqID	Chr04 / NC_080390.1
坐标与链方向	53934312 - 53937175 / `+`

ID 对照

NCBI Gene ID	`LOC131020695`
GeneID	`131020695`
locus_tag	`-`
NCBI Name	`LOC131020695`
原始查询	`SmilChr04G003774`

查看完整 ID 对照表

功能注释

来源	GFF basic annotation; NCBI GO GAF; Pfam-A/HMMER; Arabidopsis/Rice homolog
描述	protein BRI1-5 ENHANCED 1-like
产物	protein BRI1-5 ENHANCED 1-like
Arabidopsis	`AT2G45400` (BEN1) NAD(P)-binding Rossmann-fold superfamily protein [Source:NCBI gene (formerly Entrezgene);Acc:819146] identity=45.1; qcov=1.01; evalue=1.52e-95; confidence=high
Rice	`Os04g0630400` - identity=37.6; qcov=1.05; evalue=3.27e-60; confidence=medium
GO	GO:0016616 (oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor)
KEGG	-
Pfam	PF01073 (3Beta_HSD); PF01370 (Epimerase); PF05368 (NmrA); PF07993 (NAD_binding_4); PF13460 (NAD_binding_10); PF16363 (GDP_Man_Dehyd)
InterPro	-
eggNOG	-
NR	GeneID:131020695

打开注释模块

亚细胞定位 Top 5

Rank	定位位置	中文	Score	Protein ID
1	Cytoplasm	细胞质	1.00000	`XP_057805666.1`
2	Cytosol	细胞质基质	1.00000	`XP_057805666.1`
3	Nucleus	细胞核	0.00000	`XP_057805666.1`
4	Chromosome	染色体	0.00000	`XP_057805666.1`
5	Centromere	着丝粒	0.00000	`XP_057805666.1`

进入亚细胞定位查询

EMS 诱变突变

下表显示该基因在丹参 EMS 材料中的前 12 个候选突变；完整结果可进入 EMS 突变库继续筛选或下载。

位置	REF	ALT	类型	影响	携带材料数	材料
`Chr4:53935485`	`G`	`A`	EMS_canonical_SNV	CDS_variant	5	B26,B37,B47,B8,C82
`Chr4:53935489`	`GTC`	`G`	2bp_deletion	frameshift_variant	20	A15,A7,B109,B111,B132,B140,B19,B28,B42,B76,B8,C20,C37,C39,C43,C51,C77,C8,C81,D9
`Chr4:53935502`	`C`	`T`	EMS_canonical_SNV	CDS_variant	1	B36
`Chr4:53935601`	`C`	`CTG`	2bp_insertion	frameshift_variant	17	B11,B113,B34,B35,B4,B5,B51,B63,B84,B86,B97,C18,C29,C33,C5,C78,C80
`Chr4:53935602`	`C`	`T`	EMS_canonical_SNV	CDS_variant	1	D10
`Chr4:53935630`	`C`	`T`	EMS_canonical_SNV	CDS_variant	1	B4
`Chr4:53935644`	`C`	`T`	EMS_canonical_SNV	stop_gained	1	C60
`Chr4:53935644`	`C`	`T`	EMS_canonical_SNV	CDS_variant	1	C60
`Chr4:53935674`	`C`	`T`	EMS_canonical_SNV	stop_gained	1	B7
`Chr4:53935674`	`C`	`T`	EMS_canonical_SNV	CDS_variant	1	B7
`Chr4:53935693`	`C`	`T`	EMS_canonical_SNV	CDS_variant	3	A4,C13,D11
`Chr4:53935696`	`C`	`T`	EMS_canonical_SNV	CDS_variant	4	A4,B10,C13,D11

进入 EMS 突变库

预测功能结构域

结构域结果来自 Pfam-A HMM 数据库和 HMMER hmmscan；位置为对应蛋白序列上的氨基酸坐标。

XP_057805666.1

330 aa

165

330

NmrA

Epimerase

3Beta_HSD

GDP_Man_Dehyd

NAD_binding_4

NAD_binding_10

PF05368 NmrA 8-128 aa PF01370 Epimerase 11-249 aa PF01073 3Beta_HSD 13-242 aa PF16363 GDP_Man_Dehyd 13-267 aa PF07993 NAD_binding_4 14-237 aa PF13460 NAD_binding_10 15-131 aa

Protein ID	来源	结构域编号	结构域名称	类型	起始 aa	终止 aa	E-value	Score	说明
`XP_057805666.1`	Pfam	`PF05368`	NmrA	Family	8	128	1.1e-08	35.8	NmrA-like family
`XP_057805666.1`	Pfam	`PF01370`	Epimerase	Family	11	249	2.3e-24	86.8	NAD dependent epimerase/dehydratase family
`XP_057805666.1`	Pfam	`PF01073`	3Beta_HSD	Family	13	242	3.3e-12	46.7	3-beta hydroxysteroid dehydrogenase/isomerase family
`XP_057805666.1`	Pfam	`PF16363`	GDP_Man_Dehyd	Domain	13	267	1e-11	45.6	GDP-mannose 4,6 dehydratase
`XP_057805666.1`	Pfam	`PF07993`	NAD_binding_4	Family	14	237	1.2e-08	35.2	Male sterility protein
`XP_057805666.1`	Pfam	`PF13460`	NAD_binding_10	Domain	15	131	6.5e-11	43.2	NAD(P)H-binding

cDNA / CDS / Protein 序列

下载基因组 DNA（仅基因区域）

每个公开基因均提供参考注释对应的转录本序列；蛋白编码基因另提供 CDS 和蛋白序列。非编码 RNA 不适用 CDS 或蛋白下载。真实 accession 的版本后缀予以保留。

cDNA

1 records

下载 cDNA FASTA

XM_057949683.1
TGTGGTGAGATGGAAAACAAAAATATAGAGAAAGGGAAAGTGTGTGTAAGTGGTGGAAATGGGTATGTTGGATCTTGGTTGGTTATGAGACTTCTTCAGCATGGTTATTCTGTCAACACAACTGTTAGATCTAAATCTAATACAGAAGTAGGGTTTCTCACAGATCTACCAGGCGCACAAGAAAGTCTTAAAATTTTCGAAGCCGATCTCAATCAACCACACAGTTTCCGAGCAGCCATCGAAGGCTGCGTCGGAGTATT...

CDS

1 records

下载 CDS FASTA

LOC131020695
ATGGAAAACAAAAATATAGAGAAAGGGAAAGTGTGTGTAAGTGGTGGAAATGGGTATGTTGGATCTTGGTTGGTTATGAGACTTCTTCAGCATGGTTATTCTGTCAACACAACTGTTAGATCTAAATCTAATACAGAAGTAGGGTTTCTCACAGATCTACCAGGCGCACAAGAAAGTCTTAAAATTTTCGAAGCCGATCTCAATCAACCACACAGTTTCCGAGCAGCCATCGAAGGCTGCGTCGGAGTATTTCTCGTCGC...

Protein

1 records

下载 Protein FASTA

XP_057805666.1
MENKNIEKGKVCVSGGNGYVGSWLVMRLLQHGYSVNTTVRSKSNTEVGFLTDLPGAQESLKIFEADLNQPHSFRAAIEGCVGVFLVAHQMHNDTTNRDDETSTTSTLAILQACLDAKTVKRVVYTSSAAAAIFAGNATAVVDEDSWSDLDLARRSSPPAVASYAAAKTLTEKAALEFAERHGLPLVTLLPTFIHGPFVGRRCPASVYALMSMFFGDDVDPYKYVAGWSDVVHVDDVASAHVFLMECADAKGRYICSAVET...

上下游序列下载

upstream/downstream 最大各 10000 bp。负链基因会自动反向互补，使最终 FASTA 为转录方向 5′→3′。

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JBrowse

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