Gene Card 基因详情

支持统一新 ID、NCBI Gene ID、GeneID、locus_tag、Transcript ID、Protein ID，以及已人工核对的文献基因名查询。页面会先解析到丹参统一基因，再整合坐标、序列、注释、亚细胞定位、EMS 突变和下载入口。

当前解析结果

`SmilChr04G003797`

染色体: Chr04 坐标: 54146744-54155850 链方向: + 类型: protein_coding

基本信息

统一新 Gene ID	`SmilChr04G003797`
名称	SmilChr04G003797
描述	brefeldin A-inhibited guanine nucleotide-exchange protein 2-like
染色体 / SeqID	Chr04 / NC_080390.1
坐标与链方向	54146744 - 54155850 / `+`

ID 对照

NCBI Gene ID	`LOC131020643`
GeneID	`131020643`
locus_tag	`-`
NCBI Name	`LOC131020643`
原始查询	`SmilChr04G003797`

查看完整 ID 对照表

功能注释

来源	GFF basic annotation; NCBI GO GAF; KEGG smil; Pfam-A/HMMER; Arabidopsis/Rice homolog
描述	brefeldin A-inhibited guanine nucleotide-exchange protein 2-like
产物	brefeldin A-inhibited guanine nucleotide-exchange protein 2-like
Arabidopsis	`AT3G60860` (AT3G60860) SEC7-like guanine nucleotide exchange family protein [Source:NCBI gene (formerly Entrezgene);Acc:825257] identity=72.6; qcov=1.02; evalue=0; confidence=high
Rice	`Os03g0246800` - identity=66.1; qcov=0.406; evalue=0; confidence=low
GO	GO:0005085 (guanyl-nucleotide exchange factor activity); GO:0005802 (trans-Golgi network); GO:0032012 (regulation of ARF protein signal transduction)
KEGG	smil04144 (Endocytosis - Salvia miltiorrhiza (redroot sage))
Pfam	PF01369 (Sec7); PF09324 (Sec7-like_HDS); PF12783 (Sec7-like_HUS); PF16206 (Mon2_C); PF16213 (DCB); PF20252 (BIG2_C); PF23325 (TPR_28)
InterPro	-
eggNOG	-
NR	GeneID:131020643

打开注释模块

亚细胞定位 Top 5

Rank	定位位置	中文	Score	Protein ID
1	Golgi apparatus	高尔基体	0.80000	`XP_057805571.1`
2	Trans-golgi network	Trans-golgi network	0.80000	`XP_057805571.1`
3	Cytosol	细胞质基质	0.40000	`XP_057805571.1`
4	Nucleus	细胞核	0.00000	`XP_057805571.1`
5	Chromosome	染色体	0.00000	`XP_057805571.1`

进入亚细胞定位查询

EMS 诱变突变

下表显示该基因在丹参 EMS 材料中的前 12 个候选突变；完整结果可进入 EMS 突变库继续筛选或下载。

位置	REF	ALT	类型	影响	携带材料数	材料
`Chr4:54147110`	`C`	`T`	EMS_canonical_SNV	CDS_variant	5	B1,B117,B126,B138,B140
`Chr4:54147170`	`G`	`A`	EMS_canonical_SNV	CDS_variant	5	B23,B77,C42,C7,D6
`Chr4:54147322`	`C`	`T`	EMS_canonical_SNV	CDS_variant	3	B106,B24,B62
`Chr4:54147332`	`G`	`A`	EMS_canonical_SNV	CDS_variant	2	B138,B25
`Chr4:54147451`	`G`	`A`	EMS_canonical_SNV	CDS_variant	3	B120,B82,C82
`Chr4:54147594`	`G`	`A`	EMS_canonical_SNV	CDS_variant	1	B80
`Chr4:54149159`	`C`	`T`	EMS_canonical_SNV	CDS_variant	2	C39,D11
`Chr4:54149207`	`C`	`T`	EMS_canonical_SNV	CDS_variant	2	C39,D11
`Chr4:54149306`	`G`	`A`	EMS_canonical_SNV	CDS_variant	1	C53
`Chr4:54149335`	`G`	`A`	EMS_canonical_SNV	CDS_variant	4	B126,B129,B38,B39
`Chr4:54150054`	`G`	`A`	EMS_canonical_SNV	CDS_variant	2	B13,C1
`Chr4:54150894`	`G`	`A`	EMS_canonical_SNV	CDS_variant	3	B1,B117,B140

进入 EMS 突变库

预测功能结构域

结构域结果来自 Pfam-A HMM 数据库和 HMMER hmmscan；位置为对应蛋白序列上的氨基酸坐标。

XP_057805571.1

1760 aa

880

1760

DCB

Sec7-like_HUS

Sec7

Sec7-like_HDS

Mon2_C

TPR_28

BIG2_C

PF16213 DCB 7-211 aa PF12783 Sec7-like_HUS 340-498 aa PF01369 Sec7 611-792 aa PF09324 Sec7-like_HDS 1158-1240 aa PF16206 Mon2_C 1325-1387 aa PF23325 TPR_28 1327-1452 aa PF20252 BIG2_C 1551-1749 aa

Protein ID	来源	结构域编号	结构域名称	类型	起始 aa	终止 aa	E-value	Score	说明
`XP_057805571.1`	Pfam	`PF16213`	DCB	Repeat	7	211	2.8e-37	128.8	Mon2/Sec7/BIG1-like, dimerisation and cyclophilin-binding domain
`XP_057805571.1`	Pfam	`PF12783`	Sec7-like_HUS	Repeat	340	498	4.1e-48	164.0	Mon2/Sec7/BIG1-like, HUS domain
`XP_057805571.1`	Pfam	`PF01369`	Sec7	Domain	611	792	1.7e-76	256.6	Sec7 domain
`XP_057805571.1`	Pfam	`PF09324`	Sec7-like_HDS	Domain	1158	1240	5.2e-30	103.9	Mon2/Sec7/BIG1-like, HDS
`XP_057805571.1`	Pfam	`PF16206`	Mon2_C	Repeat	1325	1387	1.2e-08	34.3	C-terminal region of Mon2 protein
`XP_057805571.1`	Pfam	`PF23325`	TPR_28	Repeat	1327	1452	8.8e-09	36.2	GBF1-like, tetratrico peptide repeat region
`XP_057805571.1`	Pfam	`PF20252`	BIG2_C	Domain	1551	1749	5.6e-41	141.2	BIG2 C-terminal domain

cDNA / CDS / Protein 序列

下载基因组 DNA（仅基因区域）

每个公开基因均提供参考注释对应的转录本序列；蛋白编码基因另提供 CDS 和蛋白序列。非编码 RNA 不适用 CDS 或蛋白下载。真实 accession 的版本后缀予以保留。

cDNA

1 records

下载 cDNA FASTA

XM_057949588.1
CGAGGCTAGAAAAAAGAAAATACCGTAATTTCCTGTCTAAACAAATACGTTCAATTTTTTTTTTTACTCTTTCATTTTTGAATTACAACAAATAATCTCGCTGGTAAATCTCGAGGGCTTTTTCGTCATTACGCACTAGCGTATATTTTAGACTTCCGTTCCACTTCAAATCACCGCCGATCAAAATGGCACCACCACCACCACCACCACCGCCATCTCCGCCGCGCTACTGAATAGAATCAAAATTCCGCCGCCACCTC...

CDS

1 records

下载 CDS FASTA

LOC131020643
ATGGCTTCTGCGGGAGCCGATTCCCGCCTATCTAAAGTCCTACTCCCCGCGCTCGACAAAATCATCAAAAACGCCTCATGGAGAAAGCACTCCAAACTCGCCGCCGAGTGCAAATCCGTTGTCGAGCGCCTTACCACACCCAATCAGCCCTCCTCCCCCTCCGCTGAATCCAAATCCGACTCGCCACGACCTCCACACCCCGGAGTTCTCATCGACCTCTCGCTATCCGATTCCGAGCTCATTCTCAGCCCCCTGATCAA...

Protein

1 records

下载 Protein FASTA

XP_057805571.1
MASAGADSRLSKVLLPALDKIIKNASWRKHSKLAAECKSVVERLTTPNQPSSPSAESKSDSPRPPHPGVLIDLSLSDSELILSPLINALASDHLKLVEPALDAVQKLIAHGYLHGEADTTGGDDAKLLSKLIDSACKCHDTGDETVELLVIKALLSAVTSVALRIHGDCLLQVVRTCYDVYLGSKNVVNQTTAKASLVQMLVIVFRRMEADSSTVPVHPIVVAELTEPMEKADADGSMTVFVQGFITKIMQDIDGVFSPS...

上下游序列下载

upstream/downstream 最大各 10000 bp。负链基因会自动反向互补，使最终 FASTA 为转录方向 5′→3′。

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