当前解析结果
SmilChr04G003985| 统一新 Gene ID | SmilChr04G003985 |
|---|---|
| 名称 | SmilChr04G003985 |
| 描述 | 3-hydroxy-3-methylglutaryl-coenzyme A reductase-like |
| 染色体 / SeqID | Chr04 / NC_080390.1 |
| 坐标与链方向 | 55285365 - 55287260 / - |
| NCBI Gene ID | LOC131020852 |
|---|---|
| GeneID | 131020852 |
| locus_tag | - |
| NCBI Name | LOC131020852 |
| 原始查询 | SmilChr04G003985 |
| 来源 | GFF basic annotation; NCBI GO GAF; KEGG smil; Pfam-A/HMMER; Arabidopsis/Rice homolog |
|---|---|
| 描述 | 3-hydroxy-3-methylglutaryl-coenzyme A reductase-like |
| 产物 | 3-hydroxy-3-methylglutaryl-coenzyme A reductase-like |
| Arabidopsis | AT1G76490 (HMG1)hydroxy methylglutaryl CoA reductase 1 [Source:NCBI gene (formerly Entrezgene);Acc:843982] identity=74.6; qcov=0.964; evalue=0; confidence=high |
| Rice | Os09g0492700 (HMGR)- identity=69.4; qcov=0.982; evalue=0; confidence=high |
| GO | GO:0004420 (hydroxymethylglutaryl-CoA reductase (NADPH) activity); GO:0005515 (protein binding); GO:0005778 (peroxisomal membrane); GO:0005789 (endoplasmic reticulum membrane); GO:0008299 (isoprenoid biosynthetic process); GO:0015936 (coenzyme A metabolic process); GO:0016126 (sterol biosynthetic process) |
| KEGG | smil00900 (Terpenoid backbone biosynthesis - Salvia miltiorrhiza (redroot sage)); smil01100 (Metabolic pathways - Salvia miltiorrhiza (redroot sage)); smil01110 (Biosynthesis of secondary metabolites - Salvia miltiorrhiza (redroot sage)) |
| Pfam | PF00368 (HMG-CoA_red) |
| InterPro | - |
| eggNOG | - |
| NR | GeneID:131020852 |
| Rank | 定位位置 | 中文 | Score | Protein ID |
|---|---|---|---|---|
| 1 | Endoplasmic reticulum | 内质网 | 1.00000 | XP_057805878.1 |
| 2 | Endoplasmic reticulum membrane | 内质网膜 | 0.80000 | XP_057805878.1 |
| 3 | Lipid droplet | 脂滴 | 0.20000 | XP_057805878.1 |
| 4 | Nucleus | 细胞核 | 0.00000 | XP_057805878.1 |
| 5 | Chromosome | 染色体 | 0.00000 | XP_057805878.1 |
下表显示该基因在丹参 EMS 材料中的前 12 个候选突变；完整结果可进入 EMS 突变库继续筛选或下载。
| 位置 | REF | ALT | 类型 | 影响 | 携带材料数 | 材料 |
|---|---|---|---|---|---|---|
Chr4:55285570 |
G |
A |
EMS_canonical_SNV | CDS_variant | 3 | B102,B55,C83 |
Chr4:55285605 |
C |
CA |
1bp_insertion | frameshift_variant | 100 | A1,A11,A20,A23,A24,A4,A8,A9,B10,B106,B107,B109,B11,B115,B118,B122,B123,B124,B126,B127,B128,B129,B132,B134,B137,B138,B18,B21,B23,B25,B27,B29,B30,B37,B4,B45,B48,B51,B52,B53,B54,B57,B58,B61,B64,B69,B73,B78,B79,B82,B85,B86,B87,B89,B92,B94,B96,B97,B98,C1,C12,C13,C14,C15,C16,C17,C2,C20,C21,C23,C25,C26,C28,C30,C31,C33,C36,C38,C46,C48,C5,C50,C54,C55,C6,C60,C64,C67,C70,C72,C73,C76,C79,C81,C83,C84,D10,D2,D4,D9 |
Chr4:55285609 |
AG |
A |
1bp_deletion | frameshift_variant | 104 | A1,A11,A20,A23,A24,A4,A8,A9,B10,B106,B107,B108,B109,B11,B115,B118,B122,B123,B124,B126,B127,B128,B129,B132,B134,B137,B138,B18,B21,B23,B25,B27,B29,B30,B37,B4,B45,B48,B51,B52,B53,B54,B57,B58,B61,B64,B69,B72,B73,B75,B78,B79,B82,B85,B86,B87,B89,B92,B94,B96,B97,B98,C1,C12,C13,C14,C15,C16,C17,C2,C20,C21,C23,C25,C26,C28,C30,C31,C33,C36,C38,C46,C48,C5,C50,C54,C55,C6,C60,C64,C67,C70,C72,C73,C76,C79,C81,C83,C84,D10,D2,D4,D8,D9 |
Chr4:55285867 |
G |
A |
EMS_canonical_SNV | CDS_variant | 4 | C43,C58,C61,C83 |
Chr4:55285882 |
G |
A |
EMS_canonical_SNV | CDS_variant | 3 | B52,C77,C81 |
Chr4:55285950 |
CGT |
C |
2bp_deletion | frameshift_variant | 152 | A1,A10,A11,A14,A15,A18,A19,A21,A25,A5,A6,A7,A9,B1,B103,B105,B108,B109,B11,B111,B112,B113,B114,B115,B117,B118,B120,B122,B123,B124,B13,B130,B132,B133,B134,B135,B136,B137,B139,B140,B15,B18,B19,B22,B25,B26,B3,B31,B32,B33,B34,B35,B36,B37,B39,B41,B42,B43,B45,B46,B50,B53,B55,B56,B57,B62,B63,B64,B66,B67,B68,B70,B73,B75,B76,B77,B79,B80,B82,B83,B84,B85,B86,B87,B88,B89,B9,B90,B91,B92,B93,B97,B98,B99,C10,C11,C13,C15,C17,C18,C20,C21,C24,C26,C27,C28,C29,C32,C33,C34,C35,C37,C4,C41,C43,C44,C45,C47,C48,C49,C50,C51,C52,C53,C54,C55,C56,C57,C59,C6,C60,C61,C63,C65,C66,C68,C7,C70,C71,C77,C78,C8,C80,C81,C83,C85,C87,D1,D11,D2,D7,D8 |
Chr4:55285956 |
CAG |
C |
2bp_deletion | frameshift_variant | 153 | A1,A10,A11,A14,A15,A18,A19,A21,A25,A5,A6,A7,A9,B1,B101,B103,B105,B108,B109,B11,B111,B112,B113,B114,B115,B117,B118,B120,B122,B123,B124,B13,B130,B132,B133,B134,B135,B136,B137,B139,B140,B15,B18,B19,B22,B25,B26,B3,B31,B32,B33,B34,B35,B36,B37,B38,B39,B41,B42,B43,B45,B46,B50,B53,B55,B56,B57,B62,B63,B64,B66,B67,B68,B70,B73,B75,B76,B77,B79,B80,B81,B82,B83,B84,B85,B86,B87,B88,B89,B9,B90,B91,B92,B93,B97,B98,B99,C10,C11,C13,C15,C17,C18,C20,C21,C24,C26,C27,C28,C29,C32,C33,C34,C35,C37,C4,C41,C43,C44,C45,C47,C48,C49,C50,C51,C52,C53,C54,C55,C56,C57,C59,C60,C61,C63,C65,C66,C7,C70,C71,C77,C78,C8,C80,C81,C83,C85,C87,D1,D11,D2,D7,D8 |
Chr4:55285965 |
C |
T |
EMS_canonical_SNV | CDS_variant | 2 | B102,C30 |
Chr4:55285966 |
G |
A |
EMS_canonical_SNV | CDS_variant | 4 | A22,B19,B30,C23 |
Chr4:55285980 |
C |
T |
EMS_canonical_SNV | CDS_variant | 4 | A4,C4,C5,C7 |
Chr4:55285990 |
C |
T |
EMS_canonical_SNV | CDS_variant | 4 | A22,B19,B30,C23 |
Chr4:55286035 |
G |
A |
EMS_canonical_SNV | CDS_variant | 1 | C13 |
结构域结果来自 Pfam-A HMM 数据库和 HMMER hmmscan；位置为对应蛋白序列上的氨基酸坐标。
XP_057805878.1PF00368
HMG-CoA_red 177-553 aa
| Protein ID | 来源 | 结构域编号 | 结构域名称 | 类型 | 起始 aa | 终止 aa | E-value | Score | 说明 |
|---|---|---|---|---|---|---|---|---|---|
XP_057805878.1 |
Pfam | PF00368 |
HMG-CoA_red | Family | 177 | 553 | 9.4e-146 | 486.3 | Hydroxymethylglutaryl-coenzyme A reductase |
每个公开基因均提供参考注释对应的转录本序列；蛋白编码基因另提供 CDS 和蛋白序列。非编码 RNA 不适用 CDS 或蛋白下载。真实 accession 的版本后缀予以保留。
1 records
下载 cDNA FASTA1 records
下载 CDS FASTA1 records
下载 Protein FASTAupstream/downstream 最大各 10000 bp。负链基因会自动反向互补，使最终 FASTA 为转录方向 5′→3′。