Gene Card 基因详情

支持统一新 ID、NCBI Gene ID、GeneID、locus_tag、Transcript ID、Protein ID，以及已人工核对的文献基因名查询。页面会先解析到丹参统一基因，再整合坐标、序列、注释、亚细胞定位、EMS 突变和下载入口。

当前解析结果

`SmilChr04G004001`

染色体: Chr04 坐标: 55361794-55365671 链方向: + 类型: protein_coding

基本信息

统一新 Gene ID	`SmilChr04G004001`
名称	SmilChr04G004001
描述	isocitrate dehydrogenase [NAD] regulatory subunit 1, mitochondrial
染色体 / SeqID	Chr04 / NC_080390.1
坐标与链方向	55361794 - 55365671 / `+`

ID 对照

NCBI Gene ID	`LOC131020870`
GeneID	`131020870`
locus_tag	`-`
NCBI Name	`LOC131020870`
原始查询	`SmilChr04G004001`

查看完整 ID 对照表

功能注释

来源	GFF basic annotation; NCBI GO GAF; KEGG smil; Pfam-A/HMMER; Arabidopsis/Rice homolog
描述	isocitrate dehydrogenase [NAD] regulatory subunit 1, mitochondrial
产物	isocitrate dehydrogenase [NAD] regulatory subunit 1%2C mitochondrial
Arabidopsis	`AT4G35260` (IDH1) isocitrate dehydrogenase 1 [Source:NCBI gene (formerly Entrezgene);Acc:829679] identity=83.1; qcov=1.03; evalue=0; confidence=high
Rice	`Os02g0595500` (OsIDHc) - identity=80.7; qcov=1.06; evalue=0; confidence=high
GO	GO:0004449 (isocitrate dehydrogenase (NAD+) activity); GO:0005739 (mitochondrion); GO:0006099 (tricarboxylic acid cycle); GO:0006102 (isocitrate metabolic process)
KEGG	smil00020 (Citrate cycle (TCA cycle) - Salvia miltiorrhiza (redroot sage)); smil01100 (Metabolic pathways - Salvia miltiorrhiza (redroot sage)); smil01110 (Biosynthesis of secondary metabolites - Salvia miltiorrhiza (redroot sage)); smil01200 (Carbon metabolism - Salvia miltiorrhiza (redroot sage)); smil01210 (2-Oxocarboxylic acid metabolism - Salvia miltiorrhiza (redroot sage)); smil01230 (Biosynthesis of amino acids - Salvia miltiorrhiza (redroot sage))
Pfam	PF00180 (Iso_dh)
InterPro	-
eggNOG	-
NR	GeneID:131020870

打开注释模块

亚细胞定位 Top 5

Rank	定位位置	中文	Score	Protein ID
1	Mitochondrion	线粒体	1.00000	`XP_057805898.1`
2	Mitochondrion matrix	线粒体基质	1.00000	`XP_057805898.1`
3	Nucleus	细胞核	0.00000	`XP_057805898.1`
4	Chromosome	染色体	0.00000	`XP_057805898.1`
5	Centromere	着丝粒	0.00000	`XP_057805898.1`

进入亚细胞定位查询

EMS 诱变突变

下表显示该基因在丹参 EMS 材料中的前 12 个候选突变；完整结果可进入 EMS 突变库继续筛选或下载。

位置	REF	ALT	类型	影响	携带材料数	材料
`Chr4:55362280`	`C`	`T`	EMS_canonical_SNV	CDS_variant	1	D11
`Chr4:55362328`	`C`	`T`	EMS_canonical_SNV	CDS_variant	5	B111,B118,B47,B97,C79
`Chr4:55362601`	`C`	`T`	EMS_canonical_SNV	CDS_variant	1	C59
`Chr4:55364422`	`G`	`A`	EMS_canonical_SNV	CDS_variant	1	B40
`Chr4:55364710`	`C`	`T`	EMS_canonical_SNV	CDS_variant	1	C85
`Chr4:55364752`	`G`	`A`	EMS_canonical_SNV	CDS_variant	1	C51
`Chr4:55364767`	`C`	`T`	EMS_canonical_SNV	CDS_variant	3	B50,C12,C71
`Chr4:55364974`	`C`	`T`	EMS_canonical_SNV	CDS_variant	2	B59,C14

进入 EMS 突变库

预测功能结构域

结构域结果来自 Pfam-A HMM 数据库和 HMMER hmmscan；位置为对应蛋白序列上的氨基酸坐标。

XP_057805898.1

366 aa

183

366

Iso_dh

PF00180 Iso_dh 39-361 aa

XP_057805899.1

356 aa

178

356

Iso_dh

PF00180 Iso_dh 39-351 aa

Protein ID	来源	结构域编号	结构域名称	类型	起始 aa	终止 aa	E-value	Score	说明
`XP_057805898.1`	Pfam	`PF00180`	Iso_dh	Domain	39	361	1.9e-80	271.5	Isocitrate/isopropylmalate dehydrogenase
`XP_057805899.1`	Pfam	`PF00180`	Iso_dh	Domain	39	351	2e-75	254.9	Isocitrate/isopropylmalate dehydrogenase

cDNA / CDS / Protein 序列

下载基因组 DNA（仅基因区域）

每个公开基因均提供参考注释对应的转录本序列；蛋白编码基因另提供 CDS 和蛋白序列。非编码 RNA 不适用 CDS 或蛋白下载。真实 accession 的版本后缀予以保留。

cDNA

2 records

下载 cDNA FASTA

XM_057949915.1
GGGTGGAAAATCAACTTATTTAGTTCTTTTTAATGTATATATTTATTTAAGAAATTACTTTTTAATATAATGATAAATGGTGCCAAGTTTTTATATACATATATAAAGAATACCGAAACAACCAATAAAAAAAAGAGAAAAACAAAAACAGAAGAAAGTTGTCATTAATTTTTAAAAAATTAACTTGCGAGTTACTGCACTTTAAGCTTAAAAAAGCTAAAAAATATGTAGATTTTTCGCGTCTTTTTCCCTCATAATTT...

XM_057949916.1
TGTAGATTTTTCGCGTCTTTTTCCCTCATAATTTTCCTCATATCCTCCACGCGATTTCTCTTCTTTTTCTCCAGCTGTTGTTGAGCCACCGTCAACCGCAGCAGCCACAGCCAGCCCCCAATTCCCTCAATCTAAACCCTAACATCACAGATTTGAATCTCCTCCTCAAACTCGGAATCATCTCTGCTAGCTAAGATGTCGCGGCGAGCACTTCCAATCTTCACGAAGCTCCTCTCCGGCGGCGGATCCACTACCACGAC...

CDS

2 records

下载 CDS FASTA

LOC131020870
ATGTCGCGGCGAGCACTTCCAATCTTCACGAAGCTCCTCTCCGGCGGCGGATCCACTACCACGACCCGATCCGTGACGTACATGCCCCGACCCGGCGACGGAACCCCGCGCCCCGTCACACTGATACCTGGCGACGGCGTCGGGCCGCTCGTGACCGGCGCCGTGGAGCAGGTGATGGAGGCGATGCACGCGCCGGTCTACTTCGAGAAATACGATATCCATGGCGATATGAAGACCGTGCCGCCGGAGCTGATCGAGTC...

Protein

2 records

下载 Protein FASTA

XP_057805898.1
MSRRALPIFTKLLSGGGSTTTTRSVTYMPRPGDGTPRPVTLIPGDGVGPLVTGAVEQVMEAMHAPVYFEKYDIHGDMKTVPPELIESIKKNKVCLKGGLKTPVGGGVSSLNVMLRKELDLYASLVHCFNLQGLPTRHQNVDIVVIRENTEGEYAGLEHEVVPGVVESLKVITKFCSERIAKYAFEYAYLNNRKKVTAVHKANIMKLADGLFLESCREIASKYPSIQYNEMIVDNCSMQLVSKPEQFDVMVTPNLYGNLVS...

XP_057805899.1
MSRRALPIFTKLLSGGGSTTTTRSVTYMPRPGDGTPRPVTLIPGDGVGPLVTGAVEQVMEAMHAPVYFEKYDIHGDMKTVPPELIESIKKNKVCLKGGLKTPVGGGVSSLNVMLRKELDLYASLVHCFNLQGLPTRHQNVDIVVIRENTEGEYAGLEHEVITKFCSERIAKYAFEYAYLNNRKKVTAVHKANIMKLADGLFLESCREIASKYPSIQYNEMIVDNCSMQLVSKPEQFDVMVTPNLYGNLVSNVAAGIAGGT...

上下游序列下载

upstream/downstream 最大各 10000 bp。负链基因会自动反向互补，使最终 FASTA 为转录方向 5′→3′。

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JBrowse

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