Gene Card 基因详情

支持统一新 ID、NCBI Gene ID、GeneID、locus_tag、Transcript ID、Protein ID，以及已人工核对的文献基因名查询。页面会先解析到丹参统一基因，再整合坐标、序列、注释、亚细胞定位、EMS 突变和下载入口。

当前解析结果

`SmilChr04G004173`

染色体: Chr04 坐标: 56354676-56358026 链方向: - 类型: protein_coding

基本信息

统一新 Gene ID	`SmilChr04G004173`
名称	SmilChr04G004173
描述	dihydrolipoyl dehydrogenase 1, mitochondrial-like
染色体 / SeqID	Chr04 / NC_080390.1
坐标与链方向	56354676 - 56358026 / `-`

ID 对照

NCBI Gene ID	`LOC131021055`
GeneID	`131021055`
locus_tag	`-`
NCBI Name	`LOC131021055`
原始查询	`SmilChr04G004173`

查看完整 ID 对照表

功能注释

来源	GFF basic annotation; NCBI GO GAF; KEGG smil; Pfam-A/HMMER; Arabidopsis/Rice homolog
描述	dihydrolipoyl dehydrogenase 1, mitochondrial-like
产物	dihydrolipoyl dehydrogenase 1%2C mitochondrial-like
Arabidopsis	`AT1G48030` (mtLPD1) mitochondrial lipoamide dehydrogenase 1 [Source:NCBI gene (formerly Entrezgene);Acc:841221] identity=85.2; qcov=1; evalue=0; confidence=high
Rice	`Os01g0328700` - identity=80.3; qcov=1; evalue=0; confidence=high
GO	GO:0004148 (dihydrolipoyl dehydrogenase (NADH) activity); GO:0005739 (mitochondrion); GO:0045252 (oxoglutarate dehydrogenase complex); GO:0050660 (flavin adenine dinucleotide binding)
KEGG	smil00010 (Glycolysis / Gluconeogenesis - Salvia miltiorrhiza (redroot sage)); smil00020 (Citrate cycle (TCA cycle) - Salvia miltiorrhiza (redroot sage)); smil00260 (Glycine, serine and threonine metabolism - Salvia miltiorrhiza (redroot sage)); smil00280 (Valine, leucine and isoleucine degradation - Salvia miltiorrhiza (redroot sage)); smil00310 (Lysine degradation - Salvia miltiorrhiza (redroot sage)); smil00380 (Tryptophan metabolism - Salvia miltiorrhiza (redroot sage)); smil00620 (Pyruvate metabolism - Salvia miltiorrhiza (redroot sage)); smil00630 (Glyoxylate and dicarboxylate metabolism - Salvia miltiorrhiza (redroot sage)); smil00640 (Propanoate metabolism - Salvia miltiorrhiza (redroot sage)); smil00670 (One carbon pool by folate - Salvia miltiorrhiza (redroot sage)); smil00785 (Lipoic acid metabolism - Salvia miltiorrhiza (redroot sage)); smil01100 (Metabolic pathways - Salvia miltiorrhiza (redroot sage)); smil01110 (Biosynthesis of secondary metabolites - Salvia miltiorrhiza (redroot sage)); smil01200 (Carbon metabolism - Salvia miltiorrhiza (redroot sage)); smil01210 (2-Oxocarboxylic acid metabolism - Salvia miltiorrhiza (redroot sage)); smil01240 (Biosynthesis of cofactors - Salvia miltiorrhiza (redroot sage))
Pfam	PF00070 (Pyr_redox); PF00890 (FAD_binding_2); PF01134 (GIDA); PF02852 (Pyr_redox_dim); PF07992 (Pyr_redox_2); PF12831 (FAD_oxidored); PF13450 (NAD_binding_8); PF13738 (Pyr_redox_3)
InterPro	-
eggNOG	-
NR	GeneID:131021055

打开注释模块

亚细胞定位 Top 5

Rank	定位位置	中文	Score	Protein ID
1	Mitochondrion	线粒体	1.00000	`XP_057806117.1`
2	Mitochondrion matrix	线粒体基质	1.00000	`XP_057806117.1`
3	Nucleus	细胞核	0.00000	`XP_057806117.1`
4	Chromosome	染色体	0.00000	`XP_057806117.1`
5	Centromere	着丝粒	0.00000	`XP_057806117.1`

进入亚细胞定位查询

EMS 诱变突变

下表显示该基因在丹参 EMS 材料中的前 12 个候选突变；完整结果可进入 EMS 突变库继续筛选或下载。

位置	REF	ALT	类型	影响	携带材料数	材料
`Chr4:56355158`	`C`	`T`	EMS_canonical_SNV	CDS_variant	2	A23,B82
`Chr4:56355427`	`G`	`A`	EMS_canonical_SNV	CDS_variant	2	A8,B59
`Chr4:56355434`	`C`	`T`	EMS_canonical_SNV	CDS_variant	2	C38,D11
`Chr4:56355580`	`TG`	`T`	1bp_deletion	frameshift_variant	1	C47
`Chr4:56355580`	`TG`	`T`	1bp_deletion	CDS_variant	1	C47
`Chr4:56355914`	`G`	`A`	EMS_canonical_SNV	CDS_variant	1	D11
`Chr4:56355958`	`G`	`A`	EMS_canonical_SNV	CDS_variant	1	B93
`Chr4:56357527`	`G`	`A`	EMS_canonical_SNV	CDS_variant	3	A20,B91,C86

进入 EMS 突变库

预测功能结构域

结构域结果来自 Pfam-A HMM 数据库和 HMMER hmmscan；位置为对应蛋白序列上的氨基酸坐标。

XP_057806117.1

507 aa

254

507

FAD_binding_2

FAD_oxidored

GIDA

Pyr_redox_2

NAD_binding_8

Pyr_redox_3

Pyr_redox

Pyr_redox_dim

PF00890 FAD_binding_2 45-81 aa PF12831 FAD_oxidored 45-87 aa PF01134 GIDA 45-190 aa PF07992 Pyr_redox_2 45-369 aa PF13450 NAD_binding_8 48-83 aa PF13738 Pyr_redox_3 171-353 aa PF00070 Pyr_redox 216-292 aa PF02852 Pyr_redox_dim 388-497 aa

Protein ID	来源	结构域编号	结构域名称	类型	起始 aa	终止 aa	E-value	Score	说明
`XP_057806117.1`	Pfam	`PF00890`	FAD_binding_2	Domain	45	81	4.1e-07	30.3	FAD binding domain
`XP_057806117.1`	Pfam	`PF12831`	FAD_oxidored	Family	45	87	1.6e-10	41.6	FAD dependent oxidoreductase
`XP_057806117.1`	Pfam	`PF01134`	GIDA	Family	45	190	1e-10	42.0	Glucose inhibited division protein A
`XP_057806117.1`	Pfam	`PF07992`	Pyr_redox_2	Domain	45	369	3.8e-74	250.4	Pyridine nucleotide-disulphide oxidoreductase
`XP_057806117.1`	Pfam	`PF13450`	NAD_binding_8	Domain	48	83	8.4e-07	29.9	NAD(P)-binding Rossmann-like domain
`XP_057806117.1`	Pfam	`PF13738`	Pyr_redox_3	Family	171	353	7.8e-13	49.1	Pyridine nucleotide-disulphide oxidoreductase
`XP_057806117.1`	Pfam	`PF00070`	Pyr_redox	Domain	216	292	3.4e-24	85.9	Pyridine nucleotide-disulphide oxidoreductase
`XP_057806117.1`	Pfam	`PF02852`	Pyr_redox_dim	Domain	388	497	6.9e-43	146.1	Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain

cDNA / CDS / Protein 序列

下载基因组 DNA（仅基因区域）

每个公开基因均提供参考注释对应的转录本序列；蛋白编码基因另提供 CDS 和蛋白序列。非编码 RNA 不适用 CDS 或蛋白下载。真实 accession 的版本后缀予以保留。

cDNA

1 records

下载 cDNA FASTA

XM_057950134.1
AAGTTAATATATAATGGGATTTGGCTTTCTAAACATTATTGAATTTTAATGCCCCACTAGCTGTGTTATGAGTATATTAAAAAAATAAAAGTAATAAGCATCCTACGGCGGATATGGGTTAAGTCAAAGTCAGCATCCATCGCATCCAACGGCTGCGATGAAATCTCATTTCAATCCAACTTCTTCTAAAGGCTGCGCCTATACATATATGAGGTTTGGGCTACAGAAATACAGAATTAATCAAACCCACGCAAACAAGA...

CDS

1 records

下载 CDS FASTA

LOC131021055
ATGGCGATGGCAGCAACTCTGGCTAGGCGAAGGGCGGCGGCGCTGTTCTCTCCATCGTCAAAGCACCTTCCTAGCGGAACCAAATACTCGTGGATTCTCAGCAGGGGATTCGCCACCGGATCTGATGAAAATGACGTCGTCATTATTGGCGGCGGCCCTGGCGGTTATGTCGCCGCTATCAAGGCGGCGCAGCTGGGCCTCAAGACCACCTGTATCGAGAAGCGTGGCGCCCTCGGAGGTACCTGCCTCAACGTCGGCTG...

Protein

1 records

下载 Protein FASTA

XP_057806117.1
MAMAATLARRRAAALFSPSSKHLPSGTKYSWILSRGFATGSDENDVVIIGGGPGGYVAAIKAAQLGLKTTCIEKRGALGGTCLNVGCIPSKALLHSSHMYHEAKNSFAHHGIKVSSVEVDVPAMLAQKDKAVGNLTKGIEGLFKKNKVNYVKGYGKFLSPSEVSVDTIDGGNTTVKGKHIIVATGSDVKSLPGITIDEERIVSSTGALSLKEVPKKLIVIGAGYIGLEMGSVWGRLGSEVIVVEFAADIVPSMDGEVRKQ...

上下游序列下载

upstream/downstream 最大各 10000 bp。负链基因会自动反向互补，使最终 FASTA 为转录方向 5′→3′。

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JBrowse

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