Gene Card 基因详情

支持统一新 ID、NCBI Gene ID、GeneID、locus_tag、Transcript ID、Protein ID，以及已人工核对的文献基因名查询。页面会先解析到丹参统一基因，再整合坐标、序列、注释、亚细胞定位、EMS 突变和下载入口。

当前解析结果

`SmilChr05G000004`

染色体: Chr05 坐标: 9372-18827 链方向: + 类型: protein_coding

基本信息

统一新 Gene ID	`SmilChr05G000004`
名称	SmilChr05G000004
描述	ATP-dependent DNA helicase Q-like 4A
染色体 / SeqID	Chr05 / NC_080391.1
坐标与链方向	9372 - 18827 / `+`

ID 对照

NCBI Gene ID	`LOC131026489`
GeneID	`131026489`
locus_tag	`-`
NCBI Name	`LOC131026489`
原始查询	`SmilChr05G000004`

查看完整 ID 对照表

功能注释

来源	GFF basic annotation; NCBI GO GAF; KEGG smil; Pfam-A/HMMER; Arabidopsis/Rice homolog
描述	ATP-dependent DNA helicase Q-like 4A
产物	ATP-dependent DNA helicase Q-like 4A
Arabidopsis	`AT1G10930` (RECQ4A) DNA helicase (RECQl4A) [Source:NCBI gene (formerly Entrezgene);Acc:837636] identity=59.3; qcov=0.988; evalue=0; confidence=high
Rice	`Os04g0433800` (OsRecQl4) - identity=51.3; qcov=0.993; evalue=0; confidence=high
GO	GO:0000724 (double-strand break repair via homologous recombination); GO:0003677 (DNA binding); GO:0003700 (DNA-binding transcription factor activity); GO:0005524 (ATP binding); GO:0005634 (nucleus); GO:0005694 (chromosome); GO:0005737 (cytoplasm); GO:0006260 (DNA replication); GO:0006268 (GO:0006268); GO:0006355 (regulation of DNA-templated transcription); GO:0009378 (four-way junction helicase activity); GO:0043138 (3'-5' DNA helicase activity)
KEGG	smil03440 (Homologous recombination - Salvia miltiorrhiza (redroot sage)); smil03460 (Fanconi anemia pathway - Salvia miltiorrhiza (redroot sage))
Pfam	PF00270 (DEAD); PF00271 (Helicase_C); PF00570 (HRDC); PF04851 (ResIII); PF09382 (RQC); PF16124 (RecQ_Zn_bind)
InterPro	-
eggNOG	-
NR	GeneID:131026489

打开注释模块

亚细胞定位 Top 5

Rank	定位位置	中文	Score	Protein ID
1	Nucleus	细胞核	1.00000	`XP_057812339.1`
2	Nucleoplasm	核质	1.00000	`XP_057812339.1`
3	Nuclear body	核内小体	0.60000	`XP_057812339.1`
4	PML body	PML body	0.20000	`XP_057812339.1`
5	Chromosome	染色体	0.00000	`XP_057812339.1`

进入亚细胞定位查询

EMS 诱变突变

下表显示该基因在丹参 EMS 材料中的前 12 个候选突变；完整结果可进入 EMS 突变库继续筛选或下载。

位置	REF	ALT	类型	影响	携带材料数	材料
`Chr5:9916`	`G`	`A`	EMS_canonical_SNV	CDS_variant	1	C27
`Chr5:9921`	`G`	`A`	EMS_canonical_SNV	CDS_variant	3	C2,C64,C66
`Chr5:10841`	`G`	`A`	EMS_canonical_SNV	CDS_variant	3	C32,C68,C78
`Chr5:10929`	`G`	`A`	EMS_canonical_SNV	CDS_variant	2	B81,D2
`Chr5:11172`	`G`	`A`	EMS_canonical_SNV	CDS_variant	3	C37,D5,D6
`Chr5:11718`	`C`	`T`	EMS_canonical_SNV	CDS_variant	2	B4,B43
`Chr5:11791`	`GC`	`G`	1bp_deletion	frameshift_variant	88	A1,A10,A11,A15,A21,A25,A3,B105,B108,B111,B123,B124,B128,B137,B139,B140,B17,B18,B21,B23,B30,B32,B37,B38,B39,B4,B40,B43,B48,B5,B51,B53,B55,B56,B6,B63,B64,B67,B70,B71,B77,B80,B81,B82,B83,B96,B97,B99,C12,C15,C16,C18,C19,C2,C21,C22,C23,C24,C25,C27,C28,C3,C30,C31,C32,C35,C37,C44,C45,C48,C5,C53,C56,C58,C62,C63,C66,C67,C68,C7,C70,C72,C74,C84,D1,D6,D7,D9
`Chr5:12154`	`C`	`T`	EMS_canonical_SNV	stop_gained	51	A18,A19,A24,A25,A5,B101,B102,B105,B108,B120,B121,B124,B128,B130,B136,B137,B23,B25,B30,B31,B55,B56,B59,B60,B72,B94,B95,B97,C12,C14,C21,C27,C30,C31,C32,C37,C38,C43,C48,C64,C7,C70,C72,C73,C77,C78,C79,C80,D11,D2,D6
`Chr5:12190`	`A`	`AT`	1bp_insertion	frameshift_variant	73	A10,A11,A13,A14,A18,A19,A24,A25,A3,A5,B101,B105,B106,B117,B120,B121,B123,B124,B130,B132,B136,B137,B18,B21,B23,B25,B31,B39,B40,B42,B44,B53,B56,B58,B59,B63,B65,B70,B72,B80,B82,B87,B95,B97,C10,C12,C15,C16,C21,C24,C28,C31,C33,C35,C37,C43,C44,C45,C46,C48,C56,C61,C62,C64,C69,C72,C73,C77,C78,C79,C84,C9,D6
`Chr5:12491`	`G`	`A`	EMS_canonical_SNV	CDS_variant	1	B122
`Chr5:13783`	`G`	`A`	EMS_canonical_SNV	CDS_variant	1	D11
`Chr5:13817`	`C`	`T`	EMS_canonical_SNV	CDS_variant	1	B82

进入 EMS 突变库

预测功能结构域

结构域结果来自 Pfam-A HMM 数据库和 HMMER hmmscan；位置为对应蛋白序列上的氨基酸坐标。

XP_057812339.1

1208 aa

604

1208

ResIII

DEAD

Helicase_C

RecQ_Zn_bind

RQC

HRDC

PF04851 ResIII 453-620 aa PF00270 DEAD 456-625 aa PF00271 Helicase_C 662-769 aa PF16124 RecQ_Zn_bind 780-861 aa PF09382 RQC 868-985 aa PF00570 HRDC 1028-1095 aa

Protein ID	来源	结构域编号	结构域名称	类型	起始 aa	终止 aa	E-value	Score	说明
`XP_057812339.1`	Pfam	`PF04851`	ResIII	Family	453	620	2.6e-06	28.2	Type III restriction enzyme, res subunit
`XP_057812339.1`	Pfam	`PF00270`	DEAD	Domain	456	625	8.5e-27	94.6	DEAD/DEAH box helicase
`XP_057812339.1`	Pfam	`PF00271`	Helicase_C	Domain	662	769	2.7e-23	83.0	Helicase conserved C-terminal domain
`XP_057812339.1`	Pfam	`PF16124`	RecQ_Zn_bind	Domain	780	861	2.8e-14	54.3	RecQ zinc-binding
`XP_057812339.1`	Pfam	`PF09382`	RQC	Domain	868	985	1.3e-22	80.5	RQC domain
`XP_057812339.1`	Pfam	`PF00570`	HRDC	Domain	1028	1095	1.1e-15	58.0	HRDC domain

cDNA / CDS / Protein 序列

下载基因组 DNA（仅基因区域）

每个公开基因均提供参考注释对应的转录本序列；蛋白编码基因另提供 CDS 和蛋白序列。非编码 RNA 不适用 CDS 或蛋白下载。真实 accession 的版本后缀予以保留。

cDNA

1 records

下载 cDNA FASTA

XM_057956356.1
TTTGATGTCCCGCCAATCCAATCCCTCCTCCGTCTCTCTCTCTCTCCCCCTCACACACACACACACACACTCCCTCGCGGCTCGCACTTCCGGCTAATATTTGGAACTGAACTTACTATTTTCTAGGCAGTTGGTGGCGCCCTGATTAGCTCCGTATTCTCAACGGATGACAATCTGGGTTTTCCAGACGAGGAGGAACAATATTTAGTAGTGATGAAGCAAAAGCATACGAGCGGAAGCAGCTCAGATGGAGGCACGAA...

CDS

1 records

下载 CDS FASTA

LOC131026489
ATGAAGCAAAAGCATACGAGCGGAAGCAGCTCAGATGGAGGCACGAATTGTAAATTCAATTGGTCAGAGCATGCCAAAGCACATAATAACTTCTCGTGCCAAGATAAGTTCTTGAGCTCGAAATTCCTGTTCTCATTGTCAAGTCAGAAACCTCAAGTTGTTGAAGCAATGGGTGCAAGGCCTGTGCTTTGTCAAGTTCACGATGTCAGGATGCAGAGTCAGCAACTTGAAAAGGCTTGGCAGCTGCTTTCCAGCCTTCA...

Protein

1 records

下载 Protein FASTA

XP_057812339.1
MKQKHTSGSSSDGGTNCKFNWSEHAKAHNNFSCQDKFLSSKFLFSLSSQKPQVVEAMGARPVLCQVHDVRMQSQQLEKAWQLLSSLQLSSRSYSKPGKSIPLAKNVNASMSGGSRHTTQHFQSDLKSTAAGRDQNDQSFSKGDVQAGGPSKSLNSCFSTHTFKEARQVSVGQNGSHSVISDTLHKETVHHTVSKSAMHTSARNGGPTSSFSVDMDDDDILENIDVDQLVSDHYQSTPQPSLSKLPPITPHPVKDNFRGDG...

上下游序列下载

upstream/downstream 最大各 10000 bp。负链基因会自动反向互补，使最终 FASTA 为转录方向 5′→3′。

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