Gene Card 基因详情

支持统一新 ID、NCBI Gene ID、GeneID、locus_tag、Transcript ID、Protein ID，以及已人工核对的文献基因名查询。页面会先解析到丹参统一基因，再整合坐标、序列、注释、亚细胞定位、EMS 突变和下载入口。

当前解析结果

`SmilChr05G000209`

染色体: Chr05 坐标: 1657567-1663092 链方向: + 类型: protein_coding

基本信息

统一新 Gene ID	`SmilChr05G000209`
名称	SmilChr05G000209
描述	bifunctional 3-dehydroquinate dehydratase/shikimate dehydrogenase, chloroplastic-like
染色体 / SeqID	Chr05 / NC_080391.1
坐标与链方向	1657567 - 1663092 / `+`

ID 对照

NCBI Gene ID	`LOC131026626`
GeneID	`131026626`
locus_tag	`-`
NCBI Name	`LOC131026626`
原始查询	`SmilChr05G000209`

查看完整 ID 对照表

功能注释

来源	GFF basic annotation; NCBI GO GAF; KEGG smil; Pfam-A/HMMER; Arabidopsis/Rice homolog
描述	bifunctional 3-dehydroquinate dehydratase/shikimate dehydrogenase, chloroplastic-like
产物	bifunctional 3-dehydroquinate dehydratase/shikimate dehydrogenase%2C chloroplastic-like
Arabidopsis	`AT3G06350` (MEE32) dehydroquinate dehydratase, putative / shikimate dehydrogenase [Source:NCBI gene (formerly Entrezgene);Acc:819809] identity=45.8; qcov=1.02; evalue=3.29e-134; confidence=high
Rice	`Os01g0375200` (DHQDT/SDH) - identity=45.1; qcov=0.948; evalue=1.78e-116; confidence=high
GO	GO:0003855 (3-dehydroquinate dehydratase activity); GO:0004764 (shikimate 3-dehydrogenase (NADP+) activity); GO:0009423 (chorismate biosynthetic process); GO:0019632 (shikimate metabolic process)
KEGG	smil00400 (Phenylalanine, tyrosine and tryptophan biosynthesis - Salvia miltiorrhiza (redroot sage)); smil00999 (Biosynthesis of various plant secondary metabolites - Salvia miltiorrhiza (redroot sage)); smil01100 (Metabolic pathways - Salvia miltiorrhiza (redroot sage)); smil01110 (Biosynthesis of secondary metabolites - Salvia miltiorrhiza (redroot sage)); smil01230 (Biosynthesis of amino acids - Salvia miltiorrhiza (redroot sage))
Pfam	PF01487 (DHquinase_I); PF08501 (Shikimate_dh_N); PF18317 (SDH_C)
InterPro	-
eggNOG	-
NR	GeneID:131026626

打开注释模块

亚细胞定位 Top 5

Rank	定位位置	中文	Score	Protein ID
1	Cytosol	细胞质基质	1.00000	`XP_057812524.1`
2	Cytoplasm	细胞质	0.60000	`XP_057812524.1`
3	Chloroplast	叶绿体	0.40000	`XP_057812524.1`
4	Nucleus	细胞核	0.00000	`XP_057812524.1`
5	Chromosome	染色体	0.00000	`XP_057812524.1`

进入亚细胞定位查询

EMS 诱变突变

下表显示该基因在丹参 EMS 材料中的前 12 个候选突变；完整结果可进入 EMS 突变库继续筛选或下载。

位置	REF	ALT	类型	影响	携带材料数	材料
`Chr5:1658011`	`TC`	`T`	1bp_deletion	frameshift_variant	1	C14
`Chr5:1658011`	`TC`	`T`	1bp_deletion	CDS_variant	1	C14
`Chr5:1658019`	`G`	`A`	EMS_canonical_SNV	CDS_variant	1	C37
`Chr5:1658082`	`C`	`T`	EMS_canonical_SNV	CDS_variant	1	A2
`Chr5:1658104`	`G`	`A`	EMS_canonical_SNV	CDS_variant	2	B128,B136
`Chr5:1658113`	`G`	`A`	EMS_canonical_SNV	CDS_variant	1	C84
`Chr5:1658130`	`C`	`T`	EMS_canonical_SNV	CDS_variant	1	D10
`Chr5:1658153`	`TC`	`T`	1bp_deletion	frameshift_variant	1	B96
`Chr5:1658153`	`TC`	`T`	1bp_deletion	CDS_variant	1	B96
`Chr5:1658156`	`G`	`A`	EMS_canonical_SNV	CDS_variant	1	B96
`Chr5:1660740`	`G`	`A`	EMS_canonical_SNV	CDS_variant	1	B104
`Chr5:1660819`	`C`	`T`	EMS_canonical_SNV	CDS_variant	3	B17,C4,C51

进入 EMS 突变库

预测功能结构域

结构域结果来自 Pfam-A HMM 数据库和 HMMER hmmscan；位置为对应蛋白序列上的氨基酸坐标。

XP_057812524.1

504 aa

252

504

DHquinase_I

Shikimate_dh_N

SDH_C

PF01487 DHquinase_I 21-229 aa PF08501 Shikimate_dh_N 237-317 aa PF18317 SDH_C 471-497 aa

XP_057812525.1

503 aa

252

503

DHquinase_I

Shikimate_dh_N

SDH_C

PF01487 DHquinase_I 21-228 aa PF08501 Shikimate_dh_N 236-316 aa PF18317 SDH_C 470-496 aa

Protein ID	来源	结构域编号	结构域名称	类型	起始 aa	终止 aa	E-value	Score	说明
`XP_057812524.1`	Pfam	`PF01487`	DHquinase_I	Domain	21	229	7.9e-35	121.6	Type I 3-dehydroquinase
`XP_057812524.1`	Pfam	`PF08501`	Shikimate_dh_N	Domain	237	317	3.8e-23	82.3	Shikimate dehydrogenase substrate binding domain
`XP_057812524.1`	Pfam	`PF18317`	SDH_C	Domain	471	497	3.2e-09	37.1	Shikimate 5'-dehydrogenase C-terminal domain
`XP_057812525.1`	Pfam	`PF01487`	DHquinase_I	Domain	21	228	2.2e-34	120.2	Type I 3-dehydroquinase
`XP_057812525.1`	Pfam	`PF08501`	Shikimate_dh_N	Domain	236	316	3.7e-23	82.3	Shikimate dehydrogenase substrate binding domain
`XP_057812525.1`	Pfam	`PF18317`	SDH_C	Domain	470	496	3.2e-09	37.1	Shikimate 5'-dehydrogenase C-terminal domain

cDNA / CDS / Protein 序列

下载基因组 DNA（仅基因区域）

每个公开基因均提供参考注释对应的转录本序列；蛋白编码基因另提供 CDS 和蛋白序列。非编码 RNA 不适用 CDS 或蛋白下载。真实 accession 的版本后缀予以保留。

cDNA

2 records

下载 cDNA FASTA

XM_057956541.1
TAAACAAGTCATGCTATTTAATTTTAACATTGAAATCTTGACATTTCACCTATGACAAAATTAATTTAGAGAACAATCTCAACTTCGTAAGTTAATTCAATCTCGAATCAATTCAATCTCGAGCCATCGAATCTCACCTTAATCTATTGTTTACTCTTTTGCCGTGCGATATATAGCAAGCTCGCCCTCTCTCTCTCTCTCTCTCTCTCTCTCTTCTGTAAGTCAGCAGAGAGAAGCCACGAGTTGCTGAGTCAGTAATG...

XM_057956542.1
TAAACAAGTCATGCTATTTAATTTTAACATTGAAATCTTGACATTTCACCTATGACAAAATTAATTTAGAGAACAATCTCAACTTCGTAAGTTAATTCAATCTCGAATCAATTCAATCTCGAGCCATCGAATCTCACCTTAATCTATTGTTTACTCTTTTGCCGTGCGATATATAGCAAGCTCGCCCTCTCTCTCTCTCTCTCTCTCTCTCTCTTCTGTAAGTCAGCAGAGAGAAGCCACGAGTTGCTGAGTCAGTAATG...

CDS

2 records

下载 CDS FASTA

LOC131026626
ATGGTGAGAGTTGGGGTTTCCGACAATTCCAGATTGATTTGCGCCGCATTGCCTCCTGATCAATCCGTCGACCAATTGCTCAATGGCATGCATCAGGCCATGGCTCAGGGCGCGGACCTCGTCCAAATCGCCCTCGATTGCGTCTCCGATTCCGATCTCACAATCCTGCTCCGCAACAACCCCATTCCCGTCGTCCTTGTTTCCCGGCCAAAATGGGAAGGTCGTGTATGCAAAAGTCACCTACAATCTCTTCTTTTGGC...

Protein

2 records

下载 Protein FASTA

XP_057812524.1
MVRVGVSDNSRLICAALPPDQSVDQLLNGMHQAMAQGADLVQIALDCVSDSDLTILLRNNPIPVVLVSRPKWEGRVCKSHLQSLLLAKDLGADYIDLELKAASALIKEDKFHQLKSSKIIVSTYLDSFTALLEDPSLLVAEMKSTEADVIKFVWEAANITEVATAFDLLSNSQQVPMIAHCTGERGLISQLLSFKFGGLFAYGSIEGNTVPGLPSVAILRQAYGLKNINKGTQVFGLISKPVSHSKGPLLHNPTFRHAGY...

XP_057812525.1
MVRVGVSDNSRLICAALPPDQSVDQLLNGMHQAMAQGADLVQIALDCVSDSDLTILLRNNPIPVVLVSRPKWEGRVCKSHLQSLLLAKDLGADYIDLELKAASALIKEDKFHQLKSSKIIVSTYLDSFTALLEDPSLLVAEMKSTEADVIKFVWEAANITEVATAFDLLSNSQVPMIAHCTGERGLISQLLSFKFGGLFAYGSIEGNTVPGLPSVAILRQAYGLKNINKGTQVFGLISKPVSHSKGPLLHNPTFRHAGYN...

上下游序列下载

upstream/downstream 最大各 10000 bp。负链基因会自动反向互补，使最终 FASTA 为转录方向 5′→3′。

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