Gene Card 基因详情

支持统一新 ID、NCBI Gene ID、GeneID、locus_tag、Transcript ID、Protein ID，以及已人工核对的文献基因名查询。页面会先解析到丹参统一基因，再整合坐标、序列、注释、亚细胞定位、EMS 突变和下载入口。

当前解析结果

`SmilChr05G000389`

染色体: Chr05 坐标: 2919259-2921796 链方向: - 类型: protein_coding

基本信息

统一新 Gene ID	`SmilChr05G000389`
名称	SmilChr05G000389
描述	probable 3-hydroxyisobutyrate dehydrogenase, mitochondrial
染色体 / SeqID	Chr05 / NC_080391.1
坐标与链方向	2919259 - 2921796 / `-`

ID 对照

NCBI Gene ID	`LOC130985108`
GeneID	`130985108`
locus_tag	`-`
NCBI Name	`LOC130985108`
原始查询	`SmilChr05G000389`

查看完整 ID 对照表

功能注释

来源	GFF basic annotation; NCBI GO GAF; KEGG smil; Pfam-A/HMMER; Arabidopsis/Rice homolog
描述	probable 3-hydroxyisobutyrate dehydrogenase, mitochondrial
产物	probable 3-hydroxyisobutyrate dehydrogenase%2C mitochondrial
Arabidopsis	`AT4G20930` (AT4G20930) 6-phosphogluconate dehydrogenase family protein [Source:NCBI gene (formerly Entrezgene);Acc:827841] identity=66; qcov=0.949; evalue=2.54e-135; confidence=high
Rice	`Os06g0677400` (P0710B08.14-1) - identity=64; qcov=0.946; evalue=1.93e-126; confidence=high
GO	GO:0006574 (L-valine catabolic process); GO:0008442 (3-hydroxyisobutyrate dehydrogenase activity); GO:0050661 (NADP binding); GO:0051287 (NAD binding)
KEGG	smil00280 (Valine, leucine and isoleucine degradation - Salvia miltiorrhiza (redroot sage)); smil00410 (beta-Alanine metabolism - Salvia miltiorrhiza (redroot sage)); smil00640 (Propanoate metabolism - Salvia miltiorrhiza (redroot sage)); smil01100 (Metabolic pathways - Salvia miltiorrhiza (redroot sage)); smil01200 (Carbon metabolism - Salvia miltiorrhiza (redroot sage))
Pfam	PF02826 (2-Hacid_dh_C); PF03446 (NAD_binding_2); PF03807 (F420_oxidored); PF07991 (KARI_N); PF14833 (NAD_binding_11)
InterPro	-
eggNOG	-
NR	GeneID:130985108

打开注释模块

亚细胞定位 Top 5

Rank	定位位置	中文	Score	Protein ID
1	Mitochondrion	线粒体	1.00000	`XP_057763864.1`
2	Cytoplasm	细胞质	1.00000	`XP_057763868.1`
3	Mitochondrion matrix	线粒体基质	1.00000	`XP_057763864.1`
4	Peroxisome	过氧化物酶体	0.40000	`XP_057763868.1`
5	Nucleus	细胞核	0.20000	`XP_057763868.1`

进入亚细胞定位查询

EMS 诱变突变

下表显示该基因在丹参 EMS 材料中的前 12 个候选突变；完整结果可进入 EMS 突变库继续筛选或下载。

位置	REF	ALT	类型	影响	携带材料数	材料
`Chr5:2919446`	`C`	`T`	EMS_canonical_SNV	CDS_variant	4	B60,B85,C24,C72
`Chr5:2919449`	`C`	`T`	EMS_canonical_SNV	CDS_variant	3	B3,B52,C73
`Chr5:2919772`	`G`	`A`	EMS_canonical_SNV	CDS_variant	5	A23,B123,B35,B82,C21
`Chr5:2919847`	`G`	`A`	EMS_canonical_SNV	CDS_variant	1	C7
`Chr5:2920012`	`G`	`A`	EMS_canonical_SNV	CDS_variant	1	C27
`Chr5:2920035`	`C`	`T`	EMS_canonical_SNV	CDS_variant	5	B138,C23,C27,C42,C61
`Chr5:2920228`	`C`	`T`	EMS_canonical_SNV	CDS_variant	1	B104
`Chr5:2920464`	`G`	`A`	EMS_canonical_SNV	CDS_variant	5	A25,B15,C1,C28,C75
`Chr5:2920640`	`G`	`A`	EMS_canonical_SNV	CDS_variant	1	A9
`Chr5:2920641`	`C`	`T`	EMS_canonical_SNV	CDS_variant	4	B107,B51,B88,C57
`Chr5:2920657`	`G`	`A`	EMS_canonical_SNV	CDS_variant	4	A21,A24,B124,B82
`Chr5:2920716`	`C`	`T`	EMS_canonical_SNV	CDS_variant	4	A21,A24,B124,B82

进入 EMS 突变库

预测功能结构域

结构域结果来自 Pfam-A HMM 数据库和 HMMER hmmscan；位置为对应蛋白序列上的氨基酸坐标。

XP_057763864.1

340 aa

170

340

2-Hacid_dh_C

KARI_N

F420_oxidored

NAD_binding_2

NAD_binding_11

PF02826 2-Hacid_dh_C 33-102 aa PF07991 KARI_N 34-102 aa PF03807 F420_oxidored 35-99 aa PF03446 NAD_binding_2 35-203 aa PF14833 NAD_binding_11 206-332 aa

XP_057763865.1

340 aa

170

340

2-Hacid_dh_C

KARI_N

F420_oxidored

NAD_binding_2

NAD_binding_11

PF02826 2-Hacid_dh_C 33-102 aa PF07991 KARI_N 34-102 aa PF03807 F420_oxidored 35-99 aa PF03446 NAD_binding_2 35-203 aa PF14833 NAD_binding_11 206-332 aa

XP_057763867.1

314 aa

157

314

2-Hacid_dh_C

KARI_N

F420_oxidored

NAD_binding_2

NAD_binding_11

PF02826 2-Hacid_dh_C 33-102 aa PF07991 KARI_N 34-102 aa PF03807 F420_oxidored 35-99 aa PF03446 NAD_binding_2 35-203 aa PF14833 NAD_binding_11 206-312 aa

XP_057763868.1

294 aa

147

294

NAD_binding_2

NAD_binding_11

PF03446 NAD_binding_2 20-157 aa PF14833 NAD_binding_11 160-286 aa

Protein ID	来源	结构域编号	结构域名称	类型	起始 aa	终止 aa	E-value	Score	说明
`XP_057763864.1`	Pfam	`PF02826`	2-Hacid_dh_C	Domain	33	102	2.1e-07	31.2	D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain
`XP_057763864.1`	Pfam	`PF07991`	KARI_N	Family	34	102	0.00016	22.0	Acetohydroxy acid isomeroreductase, NADPH-binding domain
`XP_057763864.1`	Pfam	`PF03807`	F420_oxidored	Family	35	99	1.6e-07	32.5	NADP oxidoreductase coenzyme F420-dependent
`XP_057763864.1`	Pfam	`PF03446`	NAD_binding_2	Domain	35	203	1.5e-44	152.6	NAD binding domain of 6-phosphogluconate dehydrogenase
`XP_057763864.1`	Pfam	`PF14833`	NAD_binding_11	Domain	206	332	1.1e-25	90.9	NAD-binding of NADP-dependent 3-hydroxyisobutyrate dehydrogenase
`XP_057763865.1`	Pfam	`PF02826`	2-Hacid_dh_C	Domain	33	102	2.1e-07	31.2	D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain
`XP_057763865.1`	Pfam	`PF07991`	KARI_N	Family	34	102	0.00016	22.0	Acetohydroxy acid isomeroreductase, NADPH-binding domain
`XP_057763865.1`	Pfam	`PF03807`	F420_oxidored	Family	35	99	1.6e-07	32.5	NADP oxidoreductase coenzyme F420-dependent
`XP_057763865.1`	Pfam	`PF03446`	NAD_binding_2	Domain	35	203	1.5e-44	152.6	NAD binding domain of 6-phosphogluconate dehydrogenase
`XP_057763865.1`	Pfam	`PF14833`	NAD_binding_11	Domain	206	332	1.1e-25	90.9	NAD-binding of NADP-dependent 3-hydroxyisobutyrate dehydrogenase
`XP_057763867.1`	Pfam	`PF02826`	2-Hacid_dh_C	Domain	33	102	1.8e-07	31.4	D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain
`XP_057763867.1`	Pfam	`PF07991`	KARI_N	Family	34	102	0.00014	22.2	Acetohydroxy acid isomeroreductase, NADPH-binding domain
`XP_057763867.1`	Pfam	`PF03807`	F420_oxidored	Family	35	99	1.5e-07	32.6	NADP oxidoreductase coenzyme F420-dependent
`XP_057763867.1`	Pfam	`PF03446`	NAD_binding_2	Domain	35	203	1.2e-44	152.9	NAD binding domain of 6-phosphogluconate dehydrogenase
`XP_057763867.1`	Pfam	`PF14833`	NAD_binding_11	Domain	206	312	4.2e-22	79.4	NAD-binding of NADP-dependent 3-hydroxyisobutyrate dehydrogenase
`XP_057763868.1`	Pfam	`PF03446`	NAD_binding_2	Domain	20	157	3.6e-29	102.6	NAD binding domain of 6-phosphogluconate dehydrogenase
`XP_057763868.1`	Pfam	`PF14833`	NAD_binding_11	Domain	160	286	8.8e-26	91.3	NAD-binding of NADP-dependent 3-hydroxyisobutyrate dehydrogenase

cDNA / CDS / Protein 序列

下载基因组 DNA（仅基因区域）

每个公开基因均提供参考注释对应的转录本序列；蛋白编码基因另提供 CDS 和蛋白序列。非编码 RNA 不适用 CDS 或蛋白下载。真实 accession 的版本后缀予以保留。

cDNA

4 records

下载 cDNA FASTA

XM_057907881.1
TTGGAAAATAGCCCTCAAAACTCGAAGAATAAAAAAGGAGGCTGGTTCTTCTTCGGAAACACCGTACCAGCTCAGCTAAAACGACACTCTCTCTCCCTTCTCAGCTAAAACGACTCTCTCTCTCTCTCTCTCTCTCTCTAGACACACACACAACACTGGTAATGGCTGTTTATAGATTGAGGTTGCTTTTATCACTTAACAGAGGCATCCATGGACTGTGCACTCGCAAGTTTTGCTCATCAACTGCTCCCTCCCAAATT...

XM_057907882.1
TAGCCCTCAAAACTCGAAGAATAAAAAAGGAGGCTGGTTCTTCTTCGGAAACACCGTACCAGCTCAGCTAAAACGACTCTCTCTCTCTCTCTCTCTAGACACACACACAACACTGGTAATGGCTGTTTATAGATTGAGGTTGCTTTTATCACTTAACAGAGGCATCCATGGACTGTGCACTCGCAAGTTTTGCTCATCAACTGCTCCCTCCCAAATTAAAAGAGTTGGATTCATAGGACTTGGAAACATGGGATCACGGA...

CDS

4 records

下载 CDS FASTA

LOC130985108
ATGGCTGTTTATAGATTGAGGTTGCTTTTATCACTTAACAGAGGCATCCATGGACTGTGCACTCGCAAGTTTTGCTCATCAACTGCTCCCTCCCAAATTAAAAGAGTTGGATTCATAGGACTTGGAAACATGGGATCACGGATGGCCGATAACTTGTTTAAAGCCGGATACAATGTTGTGGTTCATGATATTAACCATGATGTGATGAGGGCATTCTCCGAGAAAGGGTTTCTCGTGAAGAATTCGCCTCTTGAAGTTGC...

Protein

4 records

下载 Protein FASTA

XP_057763864.1
MAVYRLRLLLSLNRGIHGLCTRKFCSSTAPSQIKRVGFIGLGNMGSRMADNLFKAGYNVVVHDINHDVMRAFSEKGFLVKNSPLEVAEESDAVITMLPSSAHVMDVYTGPKGILNHADQLRSWLFIDSSTIDPQTSRKLSAAVATSSLKGGSSTPAMLDAPVSGGIVSAENGTLTFMVGGSEEAYMSARPLFLSMGKNIIHCGGPGNGSAAKICNNLAMAVSMLGVSEAYSLGQSLGIGATTLTEIFNSSSARCWSSDTY...

XP_057763865.1
MAVYRLRLLLSLNRGIHGLCTRKFCSSTAPSQIKRVGFIGLGNMGSRMADNLFKAGYNVVVHDINHDVMRAFSEKGFLVKNSPLEVAEESDAVITMLPSSAHVMDVYTGPKGILNHADQLRSWLFIDSSTIDPQTSRKLSAAVATSSLKGGSSTPAMLDAPVSGGIVSAENGTLTFMVGGSEEAYMSARPLFLSMGKNIIHCGGPGNGSAAKICNNLAMAVSMLGVSEAYSLGQSLGIGATTLTEIFNSSSARCWSSDTY...

上下游序列下载

upstream/downstream 最大各 10000 bp。负链基因会自动反向互补，使最终 FASTA 为转录方向 5′→3′。

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