Gene Card 基因详情

支持统一新 ID、NCBI Gene ID、GeneID、locus_tag、Transcript ID、Protein ID，以及已人工核对的文献基因名查询。页面会先解析到丹参统一基因，再整合坐标、序列、注释、亚细胞定位、EMS 突变和下载入口。

当前解析结果

`SmilChr05G001687`

染色体: Chr05 坐标: 16016470-16019361 链方向: + 类型: protein_coding

基本信息

统一新 Gene ID	`SmilChr05G001687`
名称	SmilChr05G001687
描述	dihydrolipoyllysine-residue acetyltransferase component 4 of pyruvate dehydrogenase complex, chloroplastic
染色体 / SeqID	Chr05 / NC_080391.1
坐标与链方向	16016470 - 16019361 / `+`

ID 对照

NCBI Gene ID	`LOC130986344`
GeneID	`130986344`
locus_tag	`-`
NCBI Name	`LOC130986344`
原始查询	`SmilChr05G001687`

查看完整 ID 对照表

功能注释

来源	GFF basic annotation; NCBI GO GAF; KEGG smil; Pfam-A/HMMER; Arabidopsis/Rice homolog
描述	dihydrolipoyllysine-residue acetyltransferase component 4 of pyruvate dehydrogenase complex, chloroplastic
产物	dihydrolipoyllysine-residue acetyltransferase component 4 of pyruvate dehydrogenase complex%2C chloroplastic
Arabidopsis	`AT3G25860` (LTA2) 2-oxoacid dehydrogenases acyltransferase family protein [Source:NCBI gene (formerly Entrezgene);Acc:822181] identity=70.5; qcov=1.02; evalue=0; confidence=high
Rice	`Os08g0431300` - identity=71.3; qcov=0.933; evalue=0; confidence=high
GO	GO:0004742 (dihydrolipoyllysine-residue acetyltransferase activity); GO:0006086 (pyruvate decarboxylation to acetyl-CoA); GO:0009534 (chloroplast thylakoid); GO:0009941 (chloroplast envelope); GO:0045254 (pyruvate dehydrogenase complex)
KEGG	smil00010 (Glycolysis / Gluconeogenesis - Salvia miltiorrhiza (redroot sage)); smil00020 (Citrate cycle (TCA cycle) - Salvia miltiorrhiza (redroot sage)); smil00620 (Pyruvate metabolism - Salvia miltiorrhiza (redroot sage)); smil00785 (Lipoic acid metabolism - Salvia miltiorrhiza (redroot sage)); smil01100 (Metabolic pathways - Salvia miltiorrhiza (redroot sage)); smil01110 (Biosynthesis of secondary metabolites - Salvia miltiorrhiza (redroot sage)); smil01200 (Carbon metabolism - Salvia miltiorrhiza (redroot sage)); smil01210 (2-Oxocarboxylic acid metabolism - Salvia miltiorrhiza (redroot sage))
Pfam	PF00198 (2-oxoacid_dh); PF00364 (Biotin_lipoyl); PF02817 (E3_binding)
InterPro	-
eggNOG	-
NR	GeneID:130986344

打开注释模块

亚细胞定位 Top 5

Rank	定位位置	中文	Score	Protein ID
1	Chloroplast	叶绿体	1.00000	`XP_057765720.1`
2	Chloroplast stroma	叶绿体基质	1.00000	`XP_057765720.1`
3	Nucleus	细胞核	0.00000	`XP_057765720.1`
4	Chromosome	染色体	0.00000	`XP_057765720.1`
5	Centromere	着丝粒	0.00000	`XP_057765720.1`

进入亚细胞定位查询

EMS 诱变突变

下表显示该基因在丹参 EMS 材料中的前 12 个候选突变；完整结果可进入 EMS 突变库继续筛选或下载。

位置	REF	ALT	类型	影响	携带材料数	材料
`Chr5:16016711`	`C`	`T`	EMS_canonical_SNV	CDS_variant	3	B119,B130,C33
`Chr5:16016998`	`C`	`T`	EMS_canonical_SNV	CDS_variant	1	B60
`Chr5:16017054`	`GA`	`G`	1bp_deletion	frameshift_variant	1	B68
`Chr5:16017054`	`GA`	`G`	1bp_deletion	CDS_variant	1	B68
`Chr5:16017258`	`G`	`A`	EMS_canonical_SNV	CDS_variant	2	B76,C53
`Chr5:16017828`	`G`	`A`	EMS_canonical_SNV	CDS_variant	1	B84
`Chr5:16018053`	`C`	`T`	EMS_canonical_SNV	CDS_variant	5	B18,B97,B98,C3,C67
`Chr5:16019058`	`C`	`T`	EMS_canonical_SNV	CDS_variant	1	A15

进入 EMS 突变库

预测功能结构域

结构域结果来自 Pfam-A HMM 数据库和 HMMER hmmscan；位置为对应蛋白序列上的氨基酸坐标。

XP_057765720.1

463 aa

232

463

Biotin_lipoyl

E3_binding

2-oxoacid_dh

PF00364 Biotin_lipoyl 40-110 aa PF02817 E3_binding 168-203 aa PF00198 2-oxoacid_dh 242-462 aa

Protein ID	来源	结构域编号	结构域名称	类型	起始 aa	终止 aa	E-value	Score	说明
`XP_057765720.1`	Pfam	`PF00364`	Biotin_lipoyl	Domain	40	110	1.4e-14	54.4	Biotin-requiring enzyme
`XP_057765720.1`	Pfam	`PF02817`	E3_binding	Family	168	203	7.6e-14	52.4	e3 binding domain
`XP_057765720.1`	Pfam	`PF00198`	2-oxoacid_dh	Domain	242	462	1.8e-64	218.1	2-oxoacid dehydrogenases acyltransferase (catalytic domain)

cDNA / CDS / Protein 序列

下载基因组 DNA（仅基因区域）

每个公开基因均提供参考注释对应的转录本序列；蛋白编码基因另提供 CDS 和蛋白序列。非编码 RNA 不适用 CDS 或蛋白下载。真实 accession 的版本后缀予以保留。

cDNA

1 records

下载 cDNA FASTA

XM_057909737.1
AACCTCATAAATTACAATTTAGCGTTGGATCAATACATTAATGCATTCTTTATGGAAATACAAATTATTTTGTCACATAGAATATGTGAAAATCACACACAGTGGCAGGCGATCTACTCAAAGCTAACTCAAACAAATTCTCCCTCGTCTTCTCCGCCCCTTCTCCCTACTACCAACACTTCCACGGCTGCTACCGCTACTCACTACCGTTCACATCCGCCGCAATGGCTTCCCTCTCTTTCTCCTCCGCCGTATCCTCC...

CDS

1 records

下载 CDS FASTA

LOC130986344
ATGGCTTCCCTCTCTTTCTCCTCCGCCGTATCCTCCTCCACTCCCTTCCTCCGCCCTTCCGCGTTCCTCCTCAGACCCCGCTCCACCCGCCTCCCCCTCGTCCGTGCCAAGATCCGCGAGATCTTCATGCCCGCCCTCAGCTCCACAATGACCGAGGGGAAAATCGTCAGCTGGGTCAAATCCGAAGGCGATGTCCTCTCCAAGGGGGAAGCCGTCGTCGTCGTCGAATCCGACAAGGCCGACATGGATGTCGAGACCTT...

Protein

1 records

下载 Protein FASTA

XP_057765720.1
MASLSFSSAVSSSTPFLRPSAFLLRPRSTRLPLVRAKIREIFMPALSSTMTEGKIVSWVKSEGDVLSKGEAVVVVESDKADMDVETFYDGILAAIVVNEGETAPVGAAIGILAETEGEIAEAKAKAAAQSSSAPAAPPPEVEKPAPVAPKAEAPAPVAAASPATPGKVVATPFAKKLAKQHKVDISELVGTGPFGRVTPEDVEKAAGITPAPKANVVVAAAPAALAASPPKAPASYPDIPGSKIVPFTTMQAAVSRNMLE...

上下游序列下载

upstream/downstream 最大各 10000 bp。负链基因会自动反向互补，使最终 FASTA 为转录方向 5′→3′。

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JBrowse

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