Gene Card 基因详情

支持统一新 ID、NCBI Gene ID、GeneID、locus_tag、Transcript ID、Protein ID，以及已人工核对的文献基因名查询。页面会先解析到丹参统一基因，再整合坐标、序列、注释、亚细胞定位、EMS 突变和下载入口。

当前解析结果

`SmilChr05G002212`

染色体: Chr05 坐标: 23581192-23589440 链方向: + 类型: protein_coding

基本信息

统一新 Gene ID	`SmilChr05G002212`
名称	SmilChr05G002212
描述	autophagy-related protein 18d-like
染色体 / SeqID	Chr05 / NC_080391.1
坐标与链方向	23581192 - 23589440 / `+`

ID 对照

NCBI Gene ID	`LOC130986773`
GeneID	`130986773`
locus_tag	`-`
NCBI Name	`LOC130986773`
原始查询	`SmilChr05G002212`

查看完整 ID 对照表

功能注释

来源	GFF basic annotation; NCBI GO GAF; Pfam-A/HMMER; Arabidopsis/Rice homolog
描述	autophagy-related protein 18d-like
产物	autophagy-related protein 18d-like
Arabidopsis	`AT3G56440` (ATG18D) autophagy 18 D-like protein [Source:NCBI gene (formerly Entrezgene);Acc:824811] identity=75; qcov=0.914; evalue=0; confidence=high
Rice	`Os01g0168500` (OsATG18b) - identity=67.2; qcov=1; evalue=0; confidence=high
GO	GO:0000422 (autophagy of mitochondrion); GO:0005515 (protein binding); GO:0005829 (cytosol); GO:0006497 (protein lipidation); GO:0019898 (extrinsic component of membrane); GO:0032266 (phosphatidylinositol-3-phosphate binding); GO:0034045 (phagophore assembly site membrane); GO:0034497 (protein localization to phagophore assembly site); GO:0044804 (nucleophagy); GO:0080025 (phosphatidylinositol-3,5-bisphosphate binding)
KEGG	-
Pfam	PF00400 (WD40); PF04419 (SERF-like_N); PF21032 (PROPPIN); PF21034 (BCAS3_WD40)
InterPro	-
eggNOG	-
NR	GeneID:130986773

打开注释模块

亚细胞定位 Top 5

Rank	定位位置	中文	Score	Protein ID
1	Cytoplasm	细胞质	1.00000	`XP_057766273.1`
2	Cytoplasmic vesicle	细胞质囊泡	1.00000	`XP_057766275.1`
3	Autophagosome	Autophagosome	0.80000	`XP_057766275.1`
4	Autophagic vesicle	Autophagic vesicle	0.80000	`XP_057766276.1`
5	Cytosol	细胞质基质	0.20000	`XP_057766273.1`

进入亚细胞定位查询

EMS 诱变突变

下表显示该基因在丹参 EMS 材料中的前 12 个候选突变；完整结果可进入 EMS 突变库继续筛选或下载。

位置	REF	ALT	类型	影响	携带材料数	材料
`Chr5:23581289`	`C`	`CCT`	2bp_insertion	frameshift_variant	2	B125,C12
`Chr5:23581289`	`C`	`CCT`	2bp_insertion	CDS_variant	2	B125,C12
`Chr5:23581542`	`GA`	`G`	1bp_deletion	frameshift_variant	6	B128,B24,C22,C43,C56,C61
`Chr5:23581552`	`G`	`A`	EMS_canonical_SNV	CDS_variant	1	B123
`Chr5:23582247`	`G`	`A`	EMS_canonical_SNV	CDS_variant	1	C45
`Chr5:23582282`	`C`	`T`	EMS_canonical_SNV	CDS_variant	1	B122
`Chr5:23582355`	`C`	`T`	EMS_canonical_SNV	stop_gained	115	A1,A13,A14,A19,A2,A23,A24,A3,A4,A5,A7,A8,A9,B10,B101,B103,B105,B109,B113,B115,B119,B120,B125,B126,B129,B131,B132,B133,B134,B137,B15,B16,B18,B19,B20,B22,B27,B28,B29,B31,B32,B33,B34,B37,B38,B4,B45,B48,B52,B53,B55,B56,B57,B6,B63,B64,B65,B67,B68,B69,B70,B71,B72,B77,B78,B79,B83,B84,B88,B93,B94,B95,B96,B97,B99,C13,C16,C23,C24,C25,C26,C27,C29,C30,C34,C36,C38,C39,C40,C42,C45,C46,C52,C53,C54,C63,C64,C66,C67,C69,C71,C72,C73,C75,C77,C8,C81,C85,C86,C87,C9,D1,D10,D7,D8
`Chr5:23584602`	`TG`	`T`	1bp_deletion	frameshift_variant	1	C8
`Chr5:23584602`	`TG`	`T`	1bp_deletion	CDS_variant	1	C8
`Chr5:23587885`	`C`	`T`	EMS_canonical_SNV	CDS_variant	1	C61

进入 EMS 突变库

预测功能结构域

结构域结果来自 Pfam-A HMM 数据库和 HMMER hmmscan；位置为对应蛋白序列上的氨基酸坐标。

XP_057766273.1

530 aa

265

530

SERF-like_N

PROPPIN

BCAS3_WD40

WD40

PF04419 SERF-like_N 48-80 aa PF21032 PROPPIN 167-409 aa PF21034 BCAS3_WD40 331-409 aa PF00400 WD40 381-406 aa

XP_057766274.1

527 aa

264

527

SERF-like_N

PROPPIN

BCAS3_WD40

WD40

PF04419 SERF-like_N 48-80 aa PF21032 PROPPIN 164-406 aa PF21034 BCAS3_WD40 328-406 aa PF00400 WD40 378-403 aa

XP_057766275.1

420 aa

210

420

PROPPIN

BCAS3_WD40

WD40

PF21032 PROPPIN 57-299 aa PF21034 BCAS3_WD40 221-299 aa PF00400 WD40 271-296 aa

XP_057766276.1

407 aa

204

407

PROPPIN

BCAS3_WD40

WD40

PF21032 PROPPIN 44-286 aa PF21034 BCAS3_WD40 208-286 aa PF00400 WD40 258-283 aa

Protein ID	来源	结构域编号	结构域名称	类型	起始 aa	终止 aa	E-value	Score	说明
`XP_057766273.1`	Pfam	`PF04419`	SERF-like_N	Disordered	48	80	3.4e-06	28.5	Small EDRK-rich factor 1/2-like, N-terminal
`XP_057766273.1`	Pfam	`PF21032`	PROPPIN	Repeat	167	409	2.2e-34	119.9	PROPPIN
`XP_057766273.1`	Pfam	`PF21034`	BCAS3_WD40	Repeat	331	409	3.4e-11	43.2	BCAS3, WD40 repeat
`XP_057766273.1`	Pfam	`PF00400`	WD40	Repeat	381	406	7.1e-08	33.4	WD domain, G-beta repeat
`XP_057766274.1`	Pfam	`PF04419`	SERF-like_N	Disordered	48	80	3.4e-06	28.6	Small EDRK-rich factor 1/2-like, N-terminal
`XP_057766274.1`	Pfam	`PF21032`	PROPPIN	Repeat	164	406	2.2e-34	119.9	PROPPIN
`XP_057766274.1`	Pfam	`PF21034`	BCAS3_WD40	Repeat	328	406	3.4e-11	43.2	BCAS3, WD40 repeat
`XP_057766274.1`	Pfam	`PF00400`	WD40	Repeat	378	403	6.9e-08	33.4	WD domain, G-beta repeat
`XP_057766275.1`	Pfam	`PF21032`	PROPPIN	Repeat	57	299	1e-34	121.0	PROPPIN
`XP_057766275.1`	Pfam	`PF21034`	BCAS3_WD40	Repeat	221	299	1.4e-11	44.4	BCAS3, WD40 repeat
`XP_057766275.1`	Pfam	`PF00400`	WD40	Repeat	271	296	1e-08	36.0	WD domain, G-beta repeat
`XP_057766276.1`	Pfam	`PF21032`	PROPPIN	Repeat	44	286	9.2e-35	121.1	PROPPIN
`XP_057766276.1`	Pfam	`PF21034`	BCAS3_WD40	Repeat	208	286	1.3e-11	44.6	BCAS3, WD40 repeat
`XP_057766276.1`	Pfam	`PF00400`	WD40	Repeat	258	283	8.8e-09	36.2	WD domain, G-beta repeat

cDNA / CDS / Protein 序列

下载基因组 DNA（仅基因区域）

每个公开基因均提供参考注释对应的转录本序列；蛋白编码基因另提供 CDS 和蛋白序列。非编码 RNA 不适用 CDS 或蛋白下载。真实 accession 的版本后缀予以保留。

cDNA

4 records

下载 cDNA FASTA

XM_057910290.1
TTTTATAAGATAAGTATGGCTTGTATAATATCAGCTTCGAAACTCATAAACTATTACGAAACTCATAAACTGTGTCCATCCAGTTGTTTTCAATACACCTCTCTCTCTCTAAACGCGGACTTTCTTCTCCGACTGCTCCGGCGCCGTTTCACCACGACTCGAGGAAATCAAAGGGAAAAAGATCGAGAAAGTGCTCAAGCTCGTAATGCCAAAGGCAAAATTAAAGATGATGGGTTGACCCCTGAGCAGCGTCGTGAAAG...

XM_057910291.1
TTTTATAAGATAAGTATGGCTTGTATAATATCAGCTTCGAAACTCATAAACTATTACGAAACTCATAAACTGTGTCCATCCAGTTGTTTTCAATACACCTCTCTCTCTCTAAACGCGGACTTTCTTCTCCGACTGCTCCGGCGCCGTTTCACCACGACTCGAGGAAATCAAAGGGAAAAAGATCGAGAAAGTGCTCAAGCTCGTAATGCCAAAGGCAAAATTAAAGATGATGGGTTGACCCCTGAGCAGCGTCGTGAAAG...

CDS

4 records

下载 CDS FASTA

LOC130986773
ATGGCTTGTATAATATCAGCTTCGAAACTCATAAACTATTACGAAACTCATAAACTGTGTCCATCCAGTTGTTTTCAATACACCTCTCTCTCTCTAAACGCGGACTTTCTTCTCCGACTGCTCCGGCGCCGTTTCACCACGACTCGAGGAAATCAAAGGGAAAAAGATCGAGAAAGTGCTCAAGCTCGTAATGCCAAAGGCAAAATTAAAGATGATGGGTTGACCCCTGAGCAGCGTCGTGAAAGAGACGCTAAGGCGCT...

Protein

4 records

下载 Protein FASTA

XP_057766273.1
MACIISASKLINYYETHKLCPSSCFQYTSLSLNADFLLRLLRRRFTTTRGNQREKDRESAQARNAKGKIKDDGLTPEQRRERDAKALQEKTAKKAAQAAGVVMLEQSQIILFLVAPANDSSQPMTSTDSASLAINPLEGCGVYEAPMDPLLQPEPQFSDNDETELYSVSWNQDYGCFAAGTSHGFRIYNCNPFKETFRRDLKTGGFKIIEMLFRCNILALVGTKLNTQYPPNNVIIWDDFQSRCIGEFSFRSEVRAVKLR...

XP_057766274.1
MACIISASKLINYYETHKLCPSSCFQYTSLSLNADFLLRLLRRRFTTTRGNQREKDRESAQARNAKGKIKDDGLTPEQRRERDAKALQEKTAKKAAQAAGVVMLEIILFLVAPANDSSQPMTSTDSASLAINPLEGCGVYEAPMDPLLQPEPQFSDNDETELYSVSWNQDYGCFAAGTSHGFRIYNCNPFKETFRRDLKTGGFKIIEMLFRCNILALVGTKLNTQYPPNNVIIWDDFQSRCIGEFSFRSEVRAVKLRRDR...

上下游序列下载

upstream/downstream 最大各 10000 bp。负链基因会自动反向互补，使最终 FASTA 为转录方向 5′→3′。

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