Gene Card 基因详情

支持统一新 ID、NCBI Gene ID、GeneID、locus_tag、Transcript ID、Protein ID，以及已人工核对的文献基因名查询。页面会先解析到丹参统一基因，再整合坐标、序列、注释、亚细胞定位、EMS 突变和下载入口。

当前解析结果

`SmilChr05G002763`

染色体: Chr05 坐标: 31979718-31982895 链方向: + 类型: protein_coding

基本信息

统一新 Gene ID	`SmilChr05G002763`
名称	SmilChr05G002763
描述	trifunctional UDP-glucose 4,6-dehydratase/UDP-4-keto-6-deoxy-D-glucose 3,5-epimerase/UDP-4-keto-L-rhamnose-reductase RHM1
染色体 / SeqID	Chr05 / NC_080391.1
坐标与链方向	31979718 - 31982895 / `+`

ID 对照

NCBI Gene ID	`LOC130986850`
GeneID	`130986850`
locus_tag	`-`
NCBI Name	`LOC130986850`
原始查询	`SmilChr05G002763`

查看完整 ID 对照表

功能注释

来源	GFF basic annotation; NCBI GO GAF; KEGG smil; Pfam-A/HMMER; Arabidopsis/Rice homolog
描述	trifunctional UDP-glucose 4,6-dehydratase/UDP-4-keto-6-deoxy-D-glucose 3,5-epimerase/UDP-4-keto-L-rhamnose-reductase RHM1
产物	trifunctional UDP-glucose 4%2C6-dehydratase/UDP-4-keto-6-deoxy-D-glucose 3%2C5-epimerase/UDP-4-keto-L-rhamnose-reductase RHM1
Arabidopsis	`AT1G78570` (RHM1) rhamnose biosynthesis 1 [Source:NCBI gene (formerly Entrezgene);Acc:844193] identity=86.1; qcov=1; evalue=0; confidence=high
Rice	`Os03g0278200` - identity=84.3; qcov=1.01; evalue=0; confidence=high
GO	GO:0008460 (dTDP-glucose 4,6-dehydratase activity); GO:0010253 (UDP-rhamnose biosynthetic process); GO:0010280 (UDP-L-rhamnose synthase activity); GO:0010315 (auxin export across the plasma membrane); GO:0050377 (UDP-glucose 4,6-dehydratase activity); GO:0051555 (flavonol biosynthetic process)
KEGG	smil00541 (Biosynthesis of various nucleotide sugars - Salvia miltiorrhiza (redroot sage)); smil01100 (Metabolic pathways - Salvia miltiorrhiza (redroot sage)); smil01250 (Biosynthesis of nucleotide sugars - Salvia miltiorrhiza (redroot sage))
Pfam	PF01073 (3Beta_HSD); PF01370 (Epimerase); PF02719 (Polysacc_synt_2); PF04321 (RmlD_sub_bind); PF07993 (NAD_binding_4); PF16363 (GDP_Man_Dehyd)
InterPro	-
eggNOG	-
NR	GeneID:130986850

打开注释模块

亚细胞定位 Top 5

Rank	定位位置	中文	Score	Protein ID
1	Cytoplasm	细胞质	1.00000	`XP_057766368.1`
2	Cytosol	细胞质基质	0.40000	`XP_057766368.1`
3	Nucleus	细胞核	0.00000	`XP_057766368.1`
4	Chromosome	染色体	0.00000	`XP_057766368.1`
5	Centromere	着丝粒	0.00000	`XP_057766368.1`

进入亚细胞定位查询

EMS 诱变突变

下表显示该基因在丹参 EMS 材料中的前 12 个候选突变；完整结果可进入 EMS 突变库继续筛选或下载。

位置	REF	ALT	类型	影响	携带材料数	材料
`Chr5:31980826`	`C`	`T`	EMS_canonical_SNV	CDS_variant	2	B102,C77
`Chr5:31980928`	`G`	`A`	EMS_canonical_SNV	CDS_variant	1	C6
`Chr5:31981027`	`C`	`T`	EMS_canonical_SNV	CDS_variant	3	A3,C55,C78
`Chr5:31981063`	`C`	`T`	EMS_canonical_SNV	CDS_variant	3	C4,C45,C55
`Chr5:31981078`	`C`	`T`	EMS_canonical_SNV	CDS_variant	5	A15,A9,B11,C4,C52
`Chr5:31981102`	`C`	`T`	EMS_canonical_SNV	CDS_variant	4	A15,A9,B30,C4
`Chr5:31981334`	`GCT`	`G`	2bp_deletion	frameshift_variant	71	A14,A20,A23,A6,A8,B105,B11,B121,B122,B124,B132,B134,B14,B15,B19,B20,B25,B28,B30,B32,B33,B35,B37,B40,B46,B47,B51,B54,B55,B61,B64,B67,B69,B7,B82,B87,B90,B91,B92,B95,B98,C12,C14,C20,C23,C24,C29,C31,C33,C36,C4,C41,C46,C5,C50,C52,C54,C6,C67,C7,C71,C72,C74,C77,C79,C8,C82,C85,C86,D10,D6
`Chr5:31981396`	`C`	`T`	EMS_canonical_SNV	CDS_variant	1	C47
`Chr5:31981399`	`C`	`T`	EMS_canonical_SNV	CDS_variant	2	B10,B17
`Chr5:31981435`	`C`	`T`	EMS_canonical_SNV	CDS_variant	1	C12
`Chr5:31981630`	`CA`	`C`	1bp_deletion	frameshift_variant	1	B87
`Chr5:31981630`	`CA`	`C`	1bp_deletion	CDS_variant	1	B87

进入 EMS 突变库

预测功能结构域

结构域结果来自 Pfam-A HMM 数据库和 HMMER hmmscan；位置为对应蛋白序列上的氨基酸坐标。

XP_057766368.1

669 aa

334

669

RmlD_sub_bind

Epimerase

Polysacc_synt_2

3Beta_HSD

GDP_Man_Dehyd

NAD_binding_4

RmlD_sub_bind

Epimerase

PF04321 RmlD_sub_bind 8-317 aa PF01370 Epimerase 9-251 aa PF02719 Polysacc_synt_2 9-283 aa PF01073 3Beta_HSD 10-235 aa PF16363 GDP_Man_Dehyd 10-315 aa PF07993 NAD_binding_4 11-191 aa PF04321 RmlD_sub_bind 383-554 aa PF01370 Epimerase 412-548 aa

Protein ID	来源	结构域编号	结构域名称	类型	起始 aa	终止 aa	E-value	Score	说明
`XP_057766368.1`	Pfam	`PF04321`	RmlD_sub_bind	Domain	8	317	4.1e-29	102.3	RmlD substrate binding domain
`XP_057766368.1`	Pfam	`PF01370`	Epimerase	Family	9	251	1.8e-68	231.2	NAD dependent epimerase/dehydratase family
`XP_057766368.1`	Pfam	`PF02719`	Polysacc_synt_2	Family	9	283	2.3e-26	93.4	Polysaccharide biosynthesis protein
`XP_057766368.1`	Pfam	`PF01073`	3Beta_HSD	Family	10	235	1e-26	94.4	3-beta hydroxysteroid dehydrogenase/isomerase family
`XP_057766368.1`	Pfam	`PF16363`	GDP_Man_Dehyd	Domain	10	315	1.1e-73	249.3	GDP-mannose 4,6 dehydratase
`XP_057766368.1`	Pfam	`PF07993`	NAD_binding_4	Family	11	191	6.3e-23	82.0	Male sterility protein
`XP_057766368.1`	Pfam	`PF04321`	RmlD_sub_bind	Domain	383	554	4.1e-29	102.3	RmlD substrate binding domain
`XP_057766368.1`	Pfam	`PF01370`	Epimerase	Family	412	548	1.8e-68	231.2	NAD dependent epimerase/dehydratase family

cDNA / CDS / Protein 序列

下载基因组 DNA（仅基因区域）

每个公开基因均提供参考注释对应的转录本序列；蛋白编码基因另提供 CDS 和蛋白序列。非编码 RNA 不适用 CDS 或蛋白下载。真实 accession 的版本后缀予以保留。

cDNA

2 records

下载 cDNA FASTA

XR_009089441.1
AATAAAACTCAATTTTGAAAAAAAAAAAAAAAAAAACGAAAAAAGAGAAAAGTAAAAAATGTAATTTGCATGATCCGCCGAGATCCTGGGCGTGTGTATATATAGGGGTGGGAAGTTGATCGACACTCCTCGCTTCTCGCTACTCAATCCCATTTCTTGGTCTAAATCATTTCCTCTCTCTTTCATTCATTACAGTTTCCTCTTGTTTTCAAGAGGGAATATTTTGTTTTTTGAATTCTTTTTCCTTTTTTATCCTCTGG...

XM_057910385.1
ATTGTTTCTATATAATAAAACTCAATTTTGAAAAAAAAAAAAAAAAAAACGAAAAAAGAGAAAAGTAAAAAATGTAATTTGCATGATCCGCCGAGATCCTGGGCGTGTGTATATATAGGGGTGGGAAGTTGATCGACACTCCTCGCTTCTCGCTACTCAATCCCATTTCTTGGTCTAAATCATTTCCTCTCTCTTTCATTCATTACAGTTTCCTCTTGTTTTCAAGAGGGAATATTTTGTTTTTTGAATTCTTTTTCCTT...

CDS

1 records

下载 CDS FASTA

LOC130986850
ATGTCGACGTTCACGCCCAAGAATATCCTAATTACCGGGGCTGCCGGATTCATTGCATCACATGTTGCGAATAGGCTAGTTCGAAACTACCCTGAGTATAAGATCATTGTTCTTGACAAACTCGATTACTGTTCCAGTCTCAAAAATCTGAATCCATCCAGCTCTTCTCCCAACTTCAAGTTTGTTAAGGGAGACATTGGTAGTGCTGACCTCGTGAACTACCTTCTCATCACTGAGAATATCGATACTATTATGCATTT...

Protein

1 records

下载 Protein FASTA

XP_057766368.1
MSTFTPKNILITGAAGFIASHVANRLVRNYPEYKIIVLDKLDYCSSLKNLNPSSSSPNFKFVKGDIGSADLVNYLLITENIDTIMHFAAQTHVDNSFGNSFEFTKNNIYGTHVLLEACKVTGQIRRFIHVSTDEVYGETDEDAVVGNHEASQLLPTNPYSATKAGAEMLVMAYGRSYGLPVITTRGNNVYGPNQFPEKLIPKFILLALRGQTLPIHGDGCNVRSYLYCEDVAEAFEVVLHKGEVGHVYNIGTKKERRVID...

上下游序列下载

upstream/downstream 最大各 10000 bp。负链基因会自动反向互补，使最终 FASTA 为转录方向 5′→3′。

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