Gene Card 基因详情

支持统一新 ID、NCBI Gene ID、GeneID、locus_tag、Transcript ID、Protein ID，以及已人工核对的文献基因名查询。页面会先解析到丹参统一基因，再整合坐标、序列、注释、亚细胞定位、EMS 突变和下载入口。

当前解析结果

`SmilChr05G003212`

染色体: Chr05 坐标: 41197219-41201463 链方向: + 类型: protein_coding

基本信息

统一新 Gene ID	`SmilChr05G003212`
名称	SmilChr05G003212
描述	probable isoprenylcysteine alpha-carbonyl methylesterase ICMEL1
染色体 / SeqID	Chr05 / NC_080391.1
坐标与链方向	41197219 - 41201463 / `+`

ID 对照

NCBI Gene ID	`LOC131024456`
GeneID	`131024456`
locus_tag	`-`
NCBI Name	`LOC131024456`
原始查询	`SmilChr05G003212`

查看完整 ID 对照表

功能注释

来源	GFF basic annotation; KEGG smil; Pfam-A/HMMER; Arabidopsis/Rice homolog
描述	probable isoprenylcysteine alpha-carbonyl methylesterase ICMEL1
产物	probable isoprenylcysteine alpha-carbonyl methylesterase ICMEL1
Arabidopsis	`AT1G26120` (ICME-LIKE1) alpha/beta-Hydrolases superfamily protein [Source:NCBI gene (formerly Entrezgene);Acc:839153] identity=74.3; qcov=0.941; evalue=0; confidence=high
Rice	`Os06g0708100` (IMCEL1) - identity=66.9; qcov=0.941; evalue=8.71e-171; confidence=high
GO	-
KEGG	smil00900 (Terpenoid backbone biosynthesis - Salvia miltiorrhiza (redroot sage)); smil01100 (Metabolic pathways - Salvia miltiorrhiza (redroot sage)); smil01110 (Biosynthesis of secondary metabolites - Salvia miltiorrhiza (redroot sage))
Pfam	PF00135 (COesterase); PF07859 (Abhydrolase_3); PF20434 (BD-FAE)
InterPro	-
eggNOG	-
NR	GeneID:131024456

打开注释模块

亚细胞定位 Top 5

Rank	定位位置	中文	Score	Protein ID
1	Endoplasmic reticulum	内质网	1.00000	`XP_057809950.1`
2	Endoplasmic reticulum membrane	内质网膜	1.00000	`XP_057809950.1`
3	Golgi apparatus	高尔基体	0.40000	`XP_057809949.1`
4	Nucleus	细胞核	0.00000	`XP_057809949.1`
5	Chromosome	染色体	0.00000	`XP_057809949.1`

进入亚细胞定位查询

EMS 诱变突变

下表显示该基因在丹参 EMS 材料中的前 12 个候选突变；完整结果可进入 EMS 突变库继续筛选或下载。

位置	REF	ALT	类型	影响	携带材料数	材料
`Chr5:41197545`	`C`	`T`	EMS_canonical_SNV	CDS_variant	3	B131,B46,B53
`Chr5:41198228`	`C`	`T`	EMS_canonical_SNV	CDS_variant	5	A13,B127,B139,C4,D2
`Chr5:41198404`	`G`	`A`	EMS_canonical_SNV	CDS_variant	1	B97
`Chr5:41200752`	`C`	`T`	EMS_canonical_SNV	CDS_variant	1	C20
`Chr5:41200753`	`C`	`T`	EMS_canonical_SNV	stop_gained	1	C20
`Chr5:41200753`	`C`	`T`	EMS_canonical_SNV	CDS_variant	1	C20

进入 EMS 突变库

预测功能结构域

结构域结果来自 Pfam-A HMM 数据库和 HMMER hmmscan；位置为对应蛋白序列上的氨基酸坐标。

XP_057809949.1

469 aa

234

469

COesterase

BD-FAE

Abhydrolase_3

PF00135 COesterase 185-291 aa PF20434 BD-FAE 185-393 aa PF07859 Abhydrolase_3 202-410 aa

XP_057809950.1

356 aa

178

356

COesterase

BD-FAE

Abhydrolase_3

PF00135 COesterase 72-177 aa PF20434 BD-FAE 72-280 aa PF07859 Abhydrolase_3 89-298 aa

Protein ID	来源	结构域编号	结构域名称	类型	起始 aa	终止 aa	E-value	Score	说明
`XP_057809949.1`	Pfam	`PF00135`	COesterase	Domain	185	291	9.8e-12	45.3	Carboxylesterase family
`XP_057809949.1`	Pfam	`PF20434`	BD-FAE	Domain	185	393	1.1e-28	100.9	BD-FAE
`XP_057809949.1`	Pfam	`PF07859`	Abhydrolase_3	Domain	202	410	9.5e-18	65.4	alpha/beta hydrolase fold
`XP_057809950.1`	Pfam	`PF00135`	COesterase	Domain	72	177	5.5e-12	46.1	Carboxylesterase family
`XP_057809950.1`	Pfam	`PF20434`	BD-FAE	Domain	72	280	5.5e-29	101.9	BD-FAE
`XP_057809950.1`	Pfam	`PF07859`	Abhydrolase_3	Domain	89	298	5.4e-18	66.2	alpha/beta hydrolase fold

cDNA / CDS / Protein 序列

下载基因组 DNA（仅基因区域）

每个公开基因均提供参考注释对应的转录本序列；蛋白编码基因另提供 CDS 和蛋白序列。非编码 RNA 不适用 CDS 或蛋白下载。真实 accession 的版本后缀予以保留。

cDNA

2 records

下载 cDNA FASTA

XM_057953966.1
GCTCCCCACAAATTCAAACTTATTAGAACTCAAAAACATTATACAATCCAAACTGTTTCATGATTTCCCTTAAATAACTACTAGAAATCTTGTCTAACAACCGTAACCTCTGCAACTCATCTCCCAATCAGAAAATTACTACACAAACCTTAAACAGTCGGTTGGGAATTGAGATTCGCATCCCAACTGTAATAATCGTATACGTATACATACTTCCCGTATACGTACAAACATGAAGCCACATATGCTTCCCGTATCCA...

XM_057953967.1
ATACAATCCAAACTGTTTCATGATTTCCCTTAAATAACTACTAGAAATCTTGTCTAACAACCGTAACCTCTGCAACTCATCTCCCAATCAGAAAATTACTACACAAACCTTAAACAGTCGGTTGGGAATTGAGATTCGCATCCCAACTGTAATAATCGTATACGTATACATACTTCCCGTATACGTACAAACATGAAGCCACATATGCTTCCCGTATCCATACCCAACGGCTCGCCATCATATTCTCCGATGATCAAAGC...

CDS

2 records

下载 CDS FASTA

LOC131024456
ATGAAGCCACATATGCTTCCCGTATCCATACCCAACGGCTCGCCATCATATTCTCCGATGATCAAAGCTGCGCCGGATACGGCGTCGTCTTTGGCGGCCTCCGCCGCAATGTTGATCGGATCGGAACTCGATTTGGGCGCGGCGGTGACGAGGATCTTGATACCGGAGGAGGAGAAGAAGAACGAAGGGAGACCCTTGATTCCCAGGACTTCTAGCTACACGGAGACGGCGACTTCGAATTCATATCAGCAGCAGAAGAG...

LOC131024456
ATGCGGGGAGAGATGCCTCTGATACTTATATGCTTACTCGGCTTGGATTTAAGTTGCTGCGATACATTGGGCTTCAAATGGATCACCAGATTTCTTGCCCTTGGCTGTTATTCTTTCCTTCTTTTTCCTGGATTTCTTCAAGTGGGATATTATTACTTCACCTCTGATAGAGTACGTAGAGGTATAGTCTATGGCGACCTTCGCAGAAATAGGCTTGATCTGTATTTGCCTAAAAATAGTGATGGACCAAAGCCAGTCAT...

Protein

2 records

下载 Protein FASTA

XP_057809949.1
MKPHMLPVSIPNGSPSYSPMIKAAPDTASSLAASAAMLIGSELDLGAAVTRILIPEEEKKNEGRPLIPRTSSYTETATSNSYQQQKRRRRAASDNSLLTLEDGGGRRSLRQDAGRDASDTYMLTRLGFKLLRYIGVGFKWITRFLALGCYSFLLFPGFLQVGYYYFTSDRVRRGIVYGDLRRNRLDLYLPKNSDGPKPVIAFVTGGAWIIGYKAWGSLLGQQLSDRDIMVACIDYRNFPQATIGDMVKDASQGISYICNN...

XP_057809950.1
MRGEMPLILICLLGLDLSCCDTLGFKWITRFLALGCYSFLLFPGFLQVGYYYFTSDRVRRGIVYGDLRRNRLDLYLPKNSDGPKPVIAFVTGGAWIIGYKAWGSLLGQQLSDRDIMVACIDYRNFPQATIGDMVKDASQGISYICNNIAEYGGDPNRVYVMGQSAGAHIAACTLLEQAIKEASGEKTSWSVSQIKAYFGLSGGYNLLNLVDHFHNRGLYRSIFLSIMEGEESLRKYSPEVVAQDPNNRNAVSLLPPIILF...

上下游序列下载

upstream/downstream 最大各 10000 bp。负链基因会自动反向互补，使最终 FASTA 为转录方向 5′→3′。

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