Gene Card 基因详情

支持统一新 ID、NCBI Gene ID、GeneID、locus_tag、Transcript ID、Protein ID，以及已人工核对的文献基因名查询。页面会先解析到丹参统一基因，再整合坐标、序列、注释、亚细胞定位、EMS 突变和下载入口。

当前解析结果

`SmilChr05G003541`

染色体: Chr05 坐标: 47282273-47293491 链方向: + 类型: protein_coding

基本信息

统一新 Gene ID	`SmilChr05G003541`
名称	SmilChr05G003541
描述	protein TOPLESS-RELATED PROTEIN 2-like
染色体 / SeqID	Chr05 / NC_080391.1
坐标与链方向	47282273 - 47293491 / `+`

ID 对照

NCBI Gene ID	`LOC131024822`
GeneID	`131024822`
locus_tag	`-`
NCBI Name	`LOC131024822`
原始查询	`SmilChr05G003541`

查看完整 ID 对照表

功能注释

来源	GFF basic annotation; NCBI GO GAF; Pfam-A/HMMER; Arabidopsis/Rice homolog
描述	protein TOPLESS-RELATED PROTEIN 2-like
产物	protein TOPLESS-RELATED PROTEIN 2-like
Arabidopsis	`AT1G15750` (TPL) Transducin family protein / WD-40 repeat family protein [Source:NCBI gene (formerly Entrezgene);Acc:838144] identity=66; qcov=1.01; evalue=0; confidence=high
Rice	`Os08g0162100` (OsLIS-L1) - identity=76.9; qcov=1; evalue=0; confidence=high
GO	GO:0005515 (protein binding); GO:0006355 (regulation of DNA-templated transcription)
KEGG	-
Pfam	PF00400 (WD40); PF17814 (LisH_TPL); PF21359 (zf_topless); PF21889 (TPR1-like_2nd); PF23383 (Beta-prop_IFT140_1st)
InterPro	-
eggNOG	-
NR	GeneID:131024822

打开注释模块

亚细胞定位 Top 5

Rank	定位位置	中文	Score	Protein ID
1	Nucleus	细胞核	1.00000	`XP_057810344.1`
2	Cytoplasm	细胞质	0.60000	`XP_057810344.1`
3	Chromosome	染色体	0.00000	`XP_057810344.1`
4	Centromere	着丝粒	0.00000	`XP_057810344.1`
5	Chromatin	染色质	0.00000	`XP_057810344.1`

进入亚细胞定位查询

EMS 诱变突变

下表显示该基因在丹参 EMS 材料中的前 12 个候选突变；完整结果可进入 EMS 突变库继续筛选或下载。

位置	REF	ALT	类型	影响	携带材料数	材料
`Chr5:47283135`	`AGG`	`A`	2bp_deletion	frameshift_variant	40	A22,A25,A4,B1,B101,B102,B11,B110,B113,B115,B118,B128,B140,B21,B27,B41,B52,B56,B57,B63,B66,B68,B70,B83,B90,B92,B93,B96,C15,C16,C17,C25,C30,C40,C47,C50,C6,C85,D7,D9
`Chr5:47283622`	`G`	`A`	EMS_canonical_SNV	CDS_variant	2	B17,C77
`Chr5:47283733`	`C`	`T`	EMS_canonical_SNV	CDS_variant	1	D11
`Chr5:47283902`	`TC`	`T`	1bp_deletion	frameshift_variant	33	A1,A10,A3,A7,B109,B11,B114,B122,B123,B131,B132,B137,B14,B19,B3,B34,B44,B46,B6,B61,B69,B73,B91,B97,C12,C26,C4,C41,C55,C61,C67,C77,C82
`Chr5:47283959`	`C`	`T`	EMS_canonical_SNV	CDS_variant	5	A23,B108,B112,B122,B94
`Chr5:47284165`	`G`	`A`	EMS_canonical_SNV	CDS_variant	1	C68
`Chr5:47284171`	`G`	`A`	EMS_canonical_SNV	CDS_variant	5	A23,B28,B37,B93,C38
`Chr5:47284184`	`G`	`A`	EMS_canonical_SNV	CDS_variant	3	B22,B69,B9
`Chr5:47284493`	`C`	`T`	EMS_canonical_SNV	CDS_variant	1	B28
`Chr5:47284529`	`A`	`ATG`	2bp_insertion	frameshift_variant	64	A13,A15,A16,A9,B104,B110,B115,B118,B12,B128,B133,B135,B18,B19,B2,B20,B24,B28,B30,B37,B39,B4,B40,B49,B50,B56,B6,B64,B7,B79,B89,B9,B90,B94,B97,C10,C15,C17,C19,C21,C31,C34,C38,C41,C43,C51,C54,C55,C60,C61,C62,C63,C66,C70,C71,C74,C75,C8,C81,C82,C87,D11,D8,D9
`Chr5:47284530`	`C`	`CT`	1bp_insertion	frameshift_variant	63	A13,A15,A16,A9,B104,B110,B115,B118,B12,B128,B133,B135,B18,B19,B2,B20,B24,B28,B30,B37,B39,B4,B40,B49,B50,B56,B6,B64,B7,B79,B89,B9,B90,B94,B97,C10,C15,C17,C19,C21,C31,C34,C38,C41,C43,C51,C54,C60,C61,C62,C63,C66,C70,C71,C74,C75,C8,C81,C82,C87,D11,D8,D9
`Chr5:47284753`	`C`	`T`	EMS_canonical_SNV	CDS_variant	1	A3

进入 EMS 突变库

预测功能结构域

结构域结果来自 Pfam-A HMM 数据库和 HMMER hmmscan；位置为对应蛋白序列上的氨基酸坐标。

XP_057810344.1

1131 aa

566

1131

LisH_TPL

TPR1-like_2nd

zf_topless

WD40

Beta-prop_IFT140_1st

WD40

PF17814 LisH_TPL 5-34 aa PF21889 TPR1-like_2nd 37-161 aa PF21359 zf_topless 164-204 aa PF00400 WD40 447-482 aa PF00400 WD40 487-525 aa PF23383 Beta-prop_IFT140_1st 852-1041 aa PF00400 WD40 913-948 aa

Protein ID	来源	结构域编号	结构域名称	类型	起始 aa	终止 aa	E-value	Score	说明
`XP_057810344.1`	Pfam	`PF17814`	LisH_TPL	Domain	5	34	3.6e-13	49.6	LisH-like dimerisation domain
`XP_057810344.1`	Pfam	`PF21889`	TPR1-like_2nd	Domain	37	161	1.1e-62	210.6	TPR1-like, CTLH-containing domain
`XP_057810344.1`	Pfam	`PF21359`	zf_topless	Domain	164	204	1e-25	89.7	TOPLESS, zinc finger domain
`XP_057810344.1`	Pfam	`PF00400`	WD40	Repeat	447	482	4.4e-32	109.9	WD domain, G-beta repeat
`XP_057810344.1`	Pfam	`PF00400`	WD40	Repeat	487	525	4.4e-32	109.9	WD domain, G-beta repeat
`XP_057810344.1`	Pfam	`PF23383`	Beta-prop_IFT140_1st	Repeat	852	1041	5.4e-16	59.0	IFT140 first beta-propeller
`XP_057810344.1`	Pfam	`PF00400`	WD40	Repeat	913	948	4.4e-32	109.9	WD domain, G-beta repeat

cDNA / CDS / Protein 序列

下载基因组 DNA（仅基因区域）

每个公开基因均提供参考注释对应的转录本序列；蛋白编码基因另提供 CDS 和蛋白序列。非编码 RNA 不适用 CDS 或蛋白下载。真实 accession 的版本后缀予以保留。

cDNA

1 records

下载 cDNA FASTA

XM_057954361.1
ATATATTAGAAGCGGTTACTGTTTTAGAGAGAGAAACAAAGTGAGACTTTTACGTACCAAAGAAAAACCATAATAGATTAGAAAGAGAAGAGAGAGTGAAAAACAGTGGGGATGGTGCAAGTGTAACTGAGAGAATTAAGGAAAGAAATTGAGTGAAAAGGAAAGAAGAAACTGCTTCTTTCAAGTAAAACCCTAGCTCTCTGCATTGTTGACTTCTGGGCTGTGCAGACGAGCTCTTCTTTACGCTTTAATAGGATGTG...

CDS

1 records

下载 CDS FASTA

LOC131024822
ATGTCGTCCTTGAGTCGAGAACTGGTTTTCTTAATATTGCAGTTCTTAGATGAGGAGAAATTCAAGGAGACTGTCCATAAGTTGGAGCAAGAATCTGGATTTTTCTTCAATATGAAGTACTTCGAGGATCAAGTCCAAGCTGGTGAATGGGAGGAAGTTGAGCGTTATTTAAGTGGATTCACCAAAGTTGAGGACAACCGTTATTCGATGAAAATCTTCTTTGAAATAAGAAAGCAGAAATATCTTGAAGCTCTTGATAG...

Protein

1 records

下载 Protein FASTA

XP_057810344.1
MSSLSRELVFLILQFLDEEKFKETVHKLEQESGFFFNMKYFEDQVQAGEWEEVERYLSGFTKVEDNRYSMKIFFEIRKQKYLEALDRQDRAKAVEILVKDLKVFASFNEDLFKEITQLLTLDNFRQNEQLSKYGDTKSARNIMLVELKKLIEANPLFRDKLTFPAFKASRLRTLINQSLNWQHQLCKNPRPNPDIKTLFTDHTCSSSNGTRAPPPGNNPLAGPVPKPGVFPPLGAHGPFQPVVSPPPSAIAGWMSTANQS...

上下游序列下载

upstream/downstream 最大各 10000 bp。负链基因会自动反向互补，使最终 FASTA 为转录方向 5′→3′。

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JBrowse

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