Gene Card 基因详情

支持统一新 ID、NCBI Gene ID、GeneID、locus_tag、Transcript ID、Protein ID，以及已人工核对的文献基因名查询。页面会先解析到丹参统一基因，再整合坐标、序列、注释、亚细胞定位、EMS 突变和下载入口。

当前解析结果

`SmilChr05G004206`

染色体: Chr05 坐标: 55957434-55960711 链方向: + 类型: protein_coding

基本信息

统一新 Gene ID	`SmilChr05G004206`
名称	SmilChr05G004206
描述	pyruvate dehydrogenase E1 component subunit alpha, mitochondrial-like
染色体 / SeqID	Chr05 / NC_080391.1
坐标与链方向	55957434 - 55960711 / `+`

ID 对照

NCBI Gene ID	`LOC131025258`
GeneID	`131025258`
locus_tag	`-`
NCBI Name	`LOC131025258`
原始查询	`SmilChr05G004206`

查看完整 ID 对照表

功能注释

来源	GFF basic annotation; NCBI GO GAF; KEGG smil; Pfam-A/HMMER; Arabidopsis/Rice homolog
描述	pyruvate dehydrogenase E1 component subunit alpha, mitochondrial-like
产物	pyruvate dehydrogenase E1 component subunit alpha%2C mitochondrial-like
Arabidopsis	`AT1G59900` (E1 ALPHA) pyruvate dehydrogenase complex E1 alpha subunit [Source:NCBI gene (formerly Entrezgene);Acc:842284] identity=80.2; qcov=1; evalue=0; confidence=high
Rice	`Os02g0739600` (OsPDHE1-A) - identity=82.2; qcov=0.946; evalue=0; confidence=high
GO	GO:0004739 (pyruvate dehydrogenase (acetyl-transferring) activity); GO:0006086 (pyruvate decarboxylation to acetyl-CoA); GO:0043231 (intracellular membrane-bounded organelle)
KEGG	smil00010 (Glycolysis / Gluconeogenesis - Salvia miltiorrhiza (redroot sage)); smil00020 (Citrate cycle (TCA cycle) - Salvia miltiorrhiza (redroot sage)); smil00620 (Pyruvate metabolism - Salvia miltiorrhiza (redroot sage)); smil00785 (Lipoic acid metabolism - Salvia miltiorrhiza (redroot sage)); smil01100 (Metabolic pathways - Salvia miltiorrhiza (redroot sage)); smil01110 (Biosynthesis of secondary metabolites - Salvia miltiorrhiza (redroot sage)); smil01200 (Carbon metabolism - Salvia miltiorrhiza (redroot sage)); smil01210 (2-Oxocarboxylic acid metabolism - Salvia miltiorrhiza (redroot sage))
Pfam	PF00676 (E1_dh); PF02775 (TPP_enzyme_C); PF13292 (DXP_synthase_N)
InterPro	-
eggNOG	-
NR	GeneID:131025258

打开注释模块

亚细胞定位 Top 5

Rank	定位位置	中文	Score	Protein ID
1	Mitochondrion	线粒体	1.00000	`XP_057810916.1`
2	Mitochondrion matrix	线粒体基质	1.00000	`XP_057810916.1`
3	Nucleus	细胞核	0.00000	`XP_057810916.1`
4	Chromosome	染色体	0.00000	`XP_057810916.1`
5	Centromere	着丝粒	0.00000	`XP_057810916.1`

进入亚细胞定位查询

EMS 诱变突变

下表显示该基因在丹参 EMS 材料中的前 12 个候选突变；完整结果可进入 EMS 突变库继续筛选或下载。

位置	REF	ALT	类型	影响	携带材料数	材料
`Chr5:55957769`	`G`	`A`	EMS_canonical_SNV	CDS_variant	1	B140
`Chr5:55957796`	`C`	`T`	EMS_canonical_SNV	CDS_variant	1	D3
`Chr5:55957850`	`C`	`T`	EMS_canonical_SNV	CDS_variant	2	B81,D11
`Chr5:55958015`	`C`	`T`	EMS_canonical_SNV	CDS_variant	5	B107,B12,B32,B55,C53
`Chr5:55958043`	`G`	`A`	EMS_canonical_SNV	CDS_variant	1	C76
`Chr5:55958099`	`G`	`A`	EMS_canonical_SNV	CDS_variant	1	D11
`Chr5:55958312`	`G`	`A`	EMS_canonical_SNV	CDS_variant	5	B11,B114,B82,C50,C7
`Chr5:55959515`	`G`	`A`	EMS_canonical_SNV	CDS_variant	2	B56,B96
`Chr5:55959847`	`G`	`A`	EMS_canonical_SNV	CDS_variant	5	A13,A18,B58,B62,C37

进入 EMS 突变库

预测功能结构域

结构域结果来自 Pfam-A HMM 数据库和 HMMER hmmscan；位置为对应蛋白序列上的氨基酸坐标。

XP_057810916.1

387 aa

194

387

E1_dh

TPP_enzyme_C

DXP_synthase_N

PF00676 E1_dh 62-357 aa PF02775 TPP_enzyme_C 147-263 aa PF13292 DXP_synthase_N 162-225 aa

Protein ID	来源	结构域编号	结构域名称	类型	起始 aa	终止 aa	E-value	Score	说明
`XP_057810916.1`	Pfam	`PF00676`	E1_dh	Domain	62	357	3.1e-120	401.4	Dehydrogenase E1 component
`XP_057810916.1`	Pfam	`PF02775`	TPP_enzyme_C	Domain	147	263	1.6e-05	25.5	Thiamine pyrophosphate enzyme, C-terminal TPP binding domain
`XP_057810916.1`	Pfam	`PF13292`	DXP_synthase_N	Family	162	225	4.9e-05	23.5	1-deoxy-D-xylulose-5-phosphate synthase

cDNA / CDS / Protein 序列

下载基因组 DNA（仅基因区域）

每个公开基因均提供参考注释对应的转录本序列；蛋白编码基因另提供 CDS 和蛋白序列。非编码 RNA 不适用 CDS 或蛋白下载。真实 accession 的版本后缀予以保留。

cDNA

1 records

下载 cDNA FASTA

XM_057954933.1
ATGATTTCAAGTACGAGAAAAACATATGTCGACATAGAAAAATATATAAAGTCCAAATATATCTATATGTAGTACTATATTATAGAAAAAGAAATTAAATACCTTATTATTATTATTAATGTAACTTTTTCCCTTTTTTTTGTTTTAATAACTTATCTTCTTCTTCTTCTACTGCTTCTACTACCTAACTAACTAAAATTCGCGCTTCCGATTCAACTCAGTGAGCAGAGAGAATCCATGGCTCAGTTAACTCGCCGCTC...

CDS

1 records

下载 CDS FASTA

LOC131025258
ATGGCTCAGTTAACTCGCCGCTCCCTGCGCCTCCTCCGGCCAACATCCGCCGCGCGCCTCCTCACCACCACCGCCTCCACGGCGCCGATCTCGATCGAGACCTCGCTCCCCTTCACCGGCCACAACATCGACCCGCCCTCCCGCACCGTGGAGACCTCCCCGCACGAGCTCCTCACCTTCTACCGCGACATGGCTCTGATGCGGCGGATGGAGATCGCCGCCGACTCTCTCTACAAGGCGAAGCTGATCCGCGGCTTCTG...

Protein

1 records

下载 Protein FASTA

XP_057810916.1
MAQLTRRSLRLLRPTSAARLLTTTASTAPISIETSLPFTGHNIDPPSRTVETSPHELLTFYRDMALMRRMEIAADSLYKAKLIRGFCHLYDGQEAVAIGMEAAITRKDCIITAYRDHCLYLGRGGTLLEAFAELMGRSGGCSKGKGGSMHFYKKENGFYGGHGIVGAQIPLGCGLAFAQKYSKDENVTFTMYGDGAANQGQLFEALNMAALWNLPAILVCENNHYGMGTAEWRAAKSPSYFKRGDYVPGLKVDGMDALAV...

上下游序列下载

upstream/downstream 最大各 10000 bp。负链基因会自动反向互补，使最终 FASTA 为转录方向 5′→3′。

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JBrowse

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