Gene Card 基因详情

支持统一新 ID、NCBI Gene ID、GeneID、locus_tag、Transcript ID、Protein ID，以及已人工核对的文献基因名查询。页面会先解析到丹参统一基因，再整合坐标、序列、注释、亚细胞定位、EMS 突变和下载入口。

当前解析结果

`SmilChr06G000330`

染色体: Chr06 坐标: 2466095-2471143 链方向: + 类型: protein_coding

基本信息

统一新 Gene ID	`SmilChr06G000330`
名称	SmilChr06G000330
描述	pyruvate dehydrogenase E1 component subunit beta-1, mitochondrial
染色体 / SeqID	Chr06 / NC_080392.1
坐标与链方向	2466095 - 2471143 / `+`

ID 对照

NCBI Gene ID	`LOC130987878`
GeneID	`130987878`
locus_tag	`-`
NCBI Name	`LOC130987878`
原始查询	`SmilChr06G000330`

查看完整 ID 对照表

功能注释

来源	GFF basic annotation; NCBI GO GAF; KEGG smil; Pfam-A/HMMER; Arabidopsis/Rice homolog
描述	pyruvate dehydrogenase E1 component subunit beta-1, mitochondrial
产物	pyruvate dehydrogenase E1 component subunit beta-1%2C mitochondrial
Arabidopsis	`AT5G50850` (MAB1) Transketolase family protein [Source:NCBI gene (formerly Entrezgene);Acc:835157] identity=82.8; qcov=1; evalue=0; confidence=high
Rice	`Os08g0536000` - identity=89.4; qcov=0.901; evalue=0; confidence=high
GO	GO:0004739 (pyruvate dehydrogenase (acetyl-transferring) activity); GO:0005967 (GO:0005967); GO:0006086 (pyruvate decarboxylation to acetyl-CoA)
KEGG	smil00010 (Glycolysis / Gluconeogenesis - Salvia miltiorrhiza (redroot sage)); smil00020 (Citrate cycle (TCA cycle) - Salvia miltiorrhiza (redroot sage)); smil00620 (Pyruvate metabolism - Salvia miltiorrhiza (redroot sage)); smil00785 (Lipoic acid metabolism - Salvia miltiorrhiza (redroot sage)); smil01100 (Metabolic pathways - Salvia miltiorrhiza (redroot sage)); smil01110 (Biosynthesis of secondary metabolites - Salvia miltiorrhiza (redroot sage)); smil01200 (Carbon metabolism - Salvia miltiorrhiza (redroot sage)); smil01210 (2-Oxocarboxylic acid metabolism - Salvia miltiorrhiza (redroot sage))
Pfam	PF02779 (Transket_pyr); PF02780 (Transketolase_C)
InterPro	-
eggNOG	-
NR	GeneID:130987878

打开注释模块

亚细胞定位 Top 5

Rank	定位位置	中文	Score	Protein ID
1	Mitochondrion	线粒体	1.00000	`XP_057767560.1`
2	Mitochondrion matrix	线粒体基质	1.00000	`XP_057767560.1`
3	Nucleus	细胞核	0.00000	`XP_057767560.1`
4	Chromosome	染色体	0.00000	`XP_057767560.1`
5	Centromere	着丝粒	0.00000	`XP_057767560.1`

进入亚细胞定位查询

EMS 诱变突变

下表显示该基因在丹参 EMS 材料中的前 12 个候选突变；完整结果可进入 EMS 突变库继续筛选或下载。

位置	REF	ALT	类型	影响	携带材料数	材料
`Chr6:2467623`	`G`	`A`	EMS_canonical_SNV	CDS_variant	2	B13,B82
`Chr6:2468231`	`C`	`T`	EMS_canonical_SNV	CDS_variant	1	D10
`Chr6:2469091`	`G`	`A`	EMS_canonical_SNV	CDS_variant	1	B86
`Chr6:2469339`	`C`	`T`	EMS_canonical_SNV	CDS_variant	1	C61
`Chr6:2470035`	`G`	`A`	EMS_canonical_SNV	CDS_variant	2	B65,C79
`Chr6:2470157`	`C`	`T`	EMS_canonical_SNV	CDS_variant	1	B136
`Chr6:2470233`	`C`	`T`	EMS_canonical_SNV	CDS_variant	2	B65,C79
`Chr6:2470791`	`G`	`A`	EMS_canonical_SNV	CDS_variant	3	A15,B9,C43

进入 EMS 突变库

预测功能结构域

结构域结果来自 Pfam-A HMM 数据库和 HMMER hmmscan；位置为对应蛋白序列上的氨基酸坐标。

XP_057767560.1

365 aa

182

365

Transket_pyr

Transketolase_C

PF02779 Transket_pyr 37-211 aa PF02780 Transketolase_C 231-353 aa

XP_057767561.1

365 aa

182

365

Transket_pyr

Transketolase_C

PF02779 Transket_pyr 37-211 aa PF02780 Transketolase_C 231-353 aa

Protein ID	来源	结构域编号	结构域名称	类型	起始 aa	终止 aa	E-value	Score	说明
`XP_057767560.1`	Pfam	`PF02779`	Transket_pyr	Domain	37	211	4.1e-45	154.3	Transketolase, pyrimidine binding domain
`XP_057767560.1`	Pfam	`PF02780`	Transketolase_C	Domain	231	353	2.1e-43	147.9	Transketolase, C-terminal domain
`XP_057767561.1`	Pfam	`PF02779`	Transket_pyr	Domain	37	211	4.1e-45	154.3	Transketolase, pyrimidine binding domain
`XP_057767561.1`	Pfam	`PF02780`	Transketolase_C	Domain	231	353	2.1e-43	147.9	Transketolase, C-terminal domain

cDNA / CDS / Protein 序列

下载基因组 DNA（仅基因区域）

每个公开基因均提供参考注释对应的转录本序列；蛋白编码基因另提供 CDS 和蛋白序列。非编码 RNA 不适用 CDS 或蛋白下载。真实 accession 的版本后缀予以保留。

cDNA

2 records

下载 cDNA FASTA

XM_057911577.1
AGTTGTACTTCCACGTAATAATCCGAGGTACAACCCTTTAAAGCAGCCTGGACCGCCAAACGAAAAACACGAAGTTTCTGTTCTAACAGTTTGCATCACCAAGAAAAGTATAGAAGAACGGAATACACTAAAATATTTGCCGTGCATCCAATTCTCTCTGTGCGATACGGAAAATTTCAAATCAGCTTCGCTTTCAGACACCCAATTCCCCGCATTCAATCGGGTCTTCTTGCTTTCTACTGGGACATCTTCAGCACTGG...

XM_057911578.1
AACACGAAGTTTCTGTTCTAACAGTTTGCATCACCAAGAAAAGTATAGAAGAACGGAATACACTAAAATATTTGCCGTGCATCCAATTCTCTCTGTGCGATACGGAAAATTTCAAATCAGCTTCGCTTTCAGACACCCAATTCCCCGCATTCAATCGGGTCTTCTTGCTTTCTACTGGGACATCTTCAGCACTGGGTAGGTTTTTTGTAGTGAAGAGTTTTAAAAATGTTGGGAATCATAAGGCAAAAGGTGGCCGGCAA...

CDS

2 records

下载 CDS FASTA

LOC130987878
ATGTTGGGAATCATAAGGCAAAAGGTGGCCGGCAAGCTCAATCATGCTCTGAATTTTGAGCAAGGAGTTGGGGCAGTTGCGTTGAGGGCATTTTCTTCCTCCGCCAAGCAGATGACAGTGCGTGATGCTTTAAACTCTGCACTTGAGGAAGAAATGTCTGCTGATCCCAAAGTGTTTATAATGGGTGAAGAGGTTGGTGAATATCAGGGTGCATATAAGATCACCAAAGGTCTTCTGGATAAATTCGGTCCCGAGAGGGT...

Protein

2 records

下载 Protein FASTA

XP_057767560.1
MLGIIRQKVAGKLNHALNFEQGVGAVALRAFSSSAKQMTVRDALNSALEEEMSADPKVFIMGEEVGEYQGAYKITKGLLDKFGPERVVDTPITEAGFTGIGVGAAYHGLRPVIEFMTFNFSMQAIDHIINSAAKSNYMSSGQISVPIVFRGPNGAAAGVGAQHSQCYAAWYGSCPGLKVLAPYSAEDARGLLKAAIRDPDPVVFLENELLYGESFPVSAETLDSSFCLPIGKAKIEREGKDVTITAYSKMVGFSLQAADI...

XP_057767561.1
MLGIIRQKVAGKLNHALNFEQGVGAVALRAFSSSAKQMTVRDALNSALEEEMSADPKVFIMGEEVGEYQGAYKITKGLLDKFGPERVVDTPITEAGFTGIGVGAAYHGLRPVIEFMTFNFSMQAIDHIINSAAKSNYMSSGQISVPIVFRGPNGAAAGVGAQHSQCYAAWYGSCPGLKVLAPYSAEDARGLLKAAIRDPDPVVFLENELLYGESFPVSAETLDSSFCLPIGKAKIEREGKDVTITAYSKMVGFSLQAADI...

上下游序列下载

upstream/downstream 最大各 10000 bp。负链基因会自动反向互补，使最终 FASTA 为转录方向 5′→3′。

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JBrowse

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