Gene Card 基因详情

支持统一新 ID、NCBI Gene ID、GeneID、locus_tag、Transcript ID、Protein ID，以及已人工核对的文献基因名查询。页面会先解析到丹参统一基因，再整合坐标、序列、注释、亚细胞定位、EMS 突变和下载入口。

当前解析结果

`SmilChr06G001014`

染色体: Chr06 坐标: 10023876-10033683 链方向: + 类型: protein_coding

基本信息

统一新 Gene ID	`SmilChr06G001014`
名称	SmilChr06G001014
描述	serine/threonine-protein kinase VPS15
染色体 / SeqID	Chr06 / NC_080392.1
坐标与链方向	10023876 - 10033683 / `+`

ID 对照

NCBI Gene ID	`LOC130988548`
GeneID	`130988548`
locus_tag	`-`
NCBI Name	`LOC130988548`
原始查询	`SmilChr06G001014`

查看完整 ID 对照表

功能注释

来源	GFF basic annotation; NCBI GO GAF; KEGG smil; Pfam-A/HMMER; Arabidopsis/Rice homolog
描述	serine/threonine-protein kinase VPS15
产物	serine/threonine-protein kinase VPS15
Arabidopsis	`AT4G29380` (VPS15) protein kinase family protein / WD-40 repeat family protein [Source:NCBI gene (formerly Entrezgene);Acc:829059] identity=65; qcov=1; evalue=0; confidence=high
Rice	`Os02g0796700` (OsWD40-57) - identity=60.6; qcov=0.28; evalue=4.63e-167; confidence=weak
GO	GO:0004674 (protein serine/threonine kinase activity); GO:0005515 (protein binding); GO:0005524 (ATP binding); GO:0005770 (late endosome); GO:0006468 (protein phosphorylation); GO:0006623 (protein targeting to vacuole); GO:0016236 (macroautophagy); GO:0030242 (autophagy of peroxisome); GO:0034271 (phosphatidylinositol 3-kinase complex, class III, type I); GO:0034272 (phosphatidylinositol 3-kinase complex, class III, type II); GO:0045324 (late endosome to vacuole transport); GO:0071561 (nucleus-vacuole junction)
KEGG	smil04136 (Autophagy - other - Salvia miltiorrhiza (redroot sage)); smil04145 (Phagocytosis - Salvia miltiorrhiza (redroot sage))
Pfam	PF00069 (Pkinase); PF00400 (WD40); PF02985 (HEAT); PF07714 (PK_Tyr_Ser-Thr); PF22956 (PIK3R4-like_middle)
InterPro	-
eggNOG	-
NR	GeneID:130988548

打开注释模块

亚细胞定位 Top 5

Rank	定位位置	中文	Score	Protein ID
1	Cytosol	细胞质基质	0.60000	`XP_057768413.1`
2	Golgi apparatus	高尔基体	0.60000	`XP_057768413.1`
3	Cytoplasm	细胞质	0.40000	`XP_057768413.1`
4	Trans-golgi network	Trans-golgi network	0.40000	`XP_057768413.1`
5	Endosome	内体	0.20000	`XP_057768413.1`

进入亚细胞定位查询

EMS 诱变突变

下表显示该基因在丹参 EMS 材料中的前 12 个候选突变；完整结果可进入 EMS 突变库继续筛选或下载。

位置	REF	ALT	类型	影响	携带材料数	材料
`Chr6:10024153`	`C`	`T`	EMS_canonical_SNV	CDS_variant	1	D10
`Chr6:10024195`	`C`	`T`	EMS_canonical_SNV	CDS_variant	2	A23,C84
`Chr6:10025050`	`G`	`A`	EMS_canonical_SNV	CDS_variant	2	B24,C8
`Chr6:10025272`	`C`	`T`	EMS_canonical_SNV	CDS_variant	3	B13,B53,B98
`Chr6:10026414`	`G`	`A`	EMS_canonical_SNV	CDS_variant	1	C37
`Chr6:10026415`	`G`	`A`	EMS_canonical_SNV	CDS_variant	1	C37
`Chr6:10028465`	`C`	`T`	EMS_canonical_SNV	CDS_variant	2	B100,B40
`Chr6:10028501`	`C`	`T`	EMS_canonical_SNV	CDS_variant	2	C64,C66
`Chr6:10029166`	`C`	`T`	EMS_canonical_SNV	CDS_variant	1	C87
`Chr6:10029509`	`G`	`A`	EMS_canonical_SNV	CDS_variant	2	A23,C84
`Chr6:10029514`	`C`	`T`	EMS_canonical_SNV	CDS_variant	2	A23,C84
`Chr6:10029545`	`C`	`T`	EMS_canonical_SNV	CDS_variant	1	B54

进入 EMS 突变库

预测功能结构域

结构域结果来自 Pfam-A HMM 数据库和 HMMER hmmscan；位置为对应蛋白序列上的氨基酸坐标。

XP_057768413.1

1548 aa

774

1548

Pkinase

PK_Tyr_Ser-Thr

PIK3R4-like_middle

HEAT

WD40

PF00069 Pkinase 31-292 aa PF07714 PK_Tyr_Ser-Thr 50-288 aa PF22956 PIK3R4-like_middle 497-860 aa PF02985 HEAT 537-565 aa PF00400 WD40 1124-1161 aa PF00400 WD40 1286-1313 aa PF00400 WD40 1518-1547 aa

Protein ID	来源	结构域编号	结构域名称	类型	起始 aa	终止 aa	E-value	Score	说明
`XP_057768413.1`	Pfam	`PF00069`	Pkinase	Domain	31	292	9.5e-22	78.4	Protein kinase domain
`XP_057768413.1`	Pfam	`PF07714`	PK_Tyr_Ser-Thr	Domain	50	288	1.4e-06	28.6	Protein tyrosine and serine/threonine kinase
`XP_057768413.1`	Pfam	`PF22956`	PIK3R4-like_middle	Repeat	497	860	8.4e-121	403.7	PIK3R4-like, middle domain
`XP_057768413.1`	Pfam	`PF02985`	HEAT	Repeat	537	565	3.6e-07	30.5	HEAT repeat
`XP_057768413.1`	Pfam	`PF00400`	WD40	Repeat	1124	1161	2e-18	66.7	WD domain, G-beta repeat
`XP_057768413.1`	Pfam	`PF00400`	WD40	Repeat	1286	1313	2e-18	66.7	WD domain, G-beta repeat
`XP_057768413.1`	Pfam	`PF00400`	WD40	Repeat	1518	1547	2e-18	66.7	WD domain, G-beta repeat

cDNA / CDS / Protein 序列

下载基因组 DNA（仅基因区域）

每个公开基因均提供参考注释对应的转录本序列；蛋白编码基因另提供 CDS 和蛋白序列。非编码 RNA 不适用 CDS 或蛋白下载。真实 accession 的版本后缀予以保留。

cDNA

1 records

下载 cDNA FASTA

XM_057912430.1
ATTGGTGGTGTCGTGTTAATATGAAAAAATAGGTCTGGAATCGGAACTCAATAATCCAAAGAAAGCCCTCTCTGAATCTTGAACGAAAAAACAGATTTTGGCACAGCTCCAAATCCTACTCCCCCATCACAACCATGGCAATCCCTTCATTAATCTTCATCCACAACTTCTAAACCCCTACCTAGATGCACTCAAATTCTCCCTAAACCAAGAATTCTTCAAAATTACCAAGTTCGATAAAATTGGGTCGAATTTGAGGG...

CDS

1 records

下载 CDS FASTA

LOC130988548
ATGGGGAACAAGATCGCGCGGACGACGCAGGCGTCGGCGACGGAATACTACCTGCATGATTTGCCGTCGTCCTACAACTTGGTGCTCAAGGAAGTTCTGGGCAGGGACCGATTCCTCAAGTCCATACTCTGCAAGCACGATGAGGGTTTGGTGCTCGTCAAGGTCTACTTCAAGCGCGGCGACTCAATTGATTTGCGAGACAATGAGCGCCGTCTCTCCCGCATTCGCGACATATTCTCCAAGCTCGATCACCCCCATGT...

Protein

1 records

下载 Protein FASTA

XP_057768413.1
MGNKIARTTQASATEYYLHDLPSSYNLVLKEVLGRDRFLKSILCKHDEGLVLVKVYFKRGDSIDLRDNERRLSRIRDIFSKLDHPHVWPFQFWLETDKAAYLLRQYFFNNLHDRLSTRPFLSLVEKKWLAFQLLYAVKQSHEHGVCHGDIKCENVLVTSWNWLYLADFASFKPTYIPYDDPSDFSFFFDTGGRRRCYVAPERFYEHGGEAQVSQDANLKPSMDIFAVGCVIAELFLEGQPLFELSQLLAYRRGQYDPTQH...

上下游序列下载

upstream/downstream 最大各 10000 bp。负链基因会自动反向互补，使最终 FASTA 为转录方向 5′→3′。

下载 upstream 下载 downstream 下载 upstream + gene + downstream

JBrowse

跳转到基因组浏览器