Gene Card 基因详情

支持统一新 ID、NCBI Gene ID、GeneID、locus_tag、Transcript ID、Protein ID，以及已人工核对的文献基因名查询。页面会先解析到丹参统一基因，再整合坐标、序列、注释、亚细胞定位、EMS 突变和下载入口。

当前解析结果

`SmilChr06G001518`

染色体: Chr06 坐标: 16352930-16358941 链方向: + 类型: protein_coding

基本信息

统一新 Gene ID	`SmilChr06G001518`
名称	SmilChr06G001518
描述	nonsense-mediated mRNA decay factor SMG7
染色体 / SeqID	Chr06 / NC_080392.1
坐标与链方向	16352930 - 16358941 / `+`

ID 对照

NCBI Gene ID	`LOC130990199`
GeneID	`130990199`
locus_tag	`-`
NCBI Name	`LOC130990199`
原始查询	`SmilChr06G001518`

查看完整 ID 对照表

功能注释

来源	GFF basic annotation; NCBI GO GAF; KEGG smil; Pfam-A/HMMER; Arabidopsis/Rice homolog
描述	nonsense-mediated mRNA decay factor SMG7
产物	nonsense-mediated mRNA decay factor SMG7
Arabidopsis	`AT5G19400` (SMG7) Telomerase activating protein Est1 [Source:NCBI gene (formerly Entrezgene);Acc:832060] identity=49.6; qcov=0.77; evalue=0; confidence=high
Rice	`Os08g0305300` - identity=43.7; qcov=1.08; evalue=0; confidence=medium
GO	GO:0000184 (nuclear-transcribed mRNA catabolic process, nonsense-mediated decay); GO:0005515 (protein binding); GO:0005697 (telomerase holoenzyme complex); GO:0042162 (telomeric repeat DNA binding); GO:0070034 (telomerase RNA binding)
KEGG	smil03015 (mRNA surveillance pathway - Salvia miltiorrhiza (redroot sage))
Pfam	PF10373 (EST1_DNA_bind); PF10374 (EST1)
InterPro	-
eggNOG	-
NR	GeneID:130990199

打开注释模块

亚细胞定位 Top 5

Rank	定位位置	中文	Score	Protein ID
1	Nucleus	细胞核	1.00000	`XP_057770407.1`
2	Cytoplasm	细胞质	0.40000	`XP_057770407.1`
3	P-body	P-body	0.20000	`XP_057770407.1`
4	Chromosome	染色体	0.00000	`XP_057770407.1`
5	Centromere	着丝粒	0.00000	`XP_057770407.1`

进入亚细胞定位查询

EMS 诱变突变

下表显示该基因在丹参 EMS 材料中的前 12 个候选突变；完整结果可进入 EMS 突变库继续筛选或下载。

位置	REF	ALT	类型	影响	携带材料数	材料
`Chr6:16354352`	`CA`	`C`	1bp_deletion	frameshift_variant	1	C65
`Chr6:16354352`	`CA`	`C`	1bp_deletion	CDS_variant	1	C65
`Chr6:16354851`	`C`	`T`	EMS_canonical_SNV	CDS_variant	2	B46,B52
`Chr6:16354930`	`G`	`A`	EMS_canonical_SNV	CDS_variant	2	B46,B52
`Chr6:16355034`	`C`	`T`	EMS_canonical_SNV	CDS_variant	3	B114,B90,B92
`Chr6:16356002`	`C`	`T`	EMS_canonical_SNV	CDS_variant	1	B113
`Chr6:16356173`	`C`	`T`	EMS_canonical_SNV	CDS_variant	5	B100,B14,B47,C34,C75
`Chr6:16356198`	`G`	`A`	EMS_canonical_SNV	CDS_variant	1	C23
`Chr6:16356539`	`C`	`T`	EMS_canonical_SNV	CDS_variant	5	B125,B139,B82,C14,C87
`Chr6:16357136`	`G`	`A`	EMS_canonical_SNV	CDS_variant	4	A14,B68,B69,B91
`Chr6:16357526`	`C`	`T`	EMS_canonical_SNV	CDS_variant	1	D5

进入 EMS 突变库

预测功能结构域

结构域结果来自 Pfam-A HMM 数据库和 HMMER hmmscan；位置为对应蛋白序列上的氨基酸坐标。

XP_057770407.1

977 aa

488

977

EST1

EST1_DNA_bind

PF10374 EST1 69-195 aa PF10373 EST1_DNA_bind 208-542 aa

Protein ID	来源	结构域编号	结构域名称	类型	起始 aa	终止 aa	E-value	Score	说明
`XP_057770407.1`	Pfam	`PF10374`	EST1	Repeat	69	195	6.5e-19	69.4	Telomerase activating protein Est1
`XP_057770407.1`	Pfam	`PF10373`	EST1_DNA_bind	Repeat	208	542	4.5e-56	191.1	Est1 DNA/RNA binding domain

cDNA / CDS / Protein 序列

下载基因组 DNA（仅基因区域）

每个公开基因均提供参考注释对应的转录本序列；蛋白编码基因另提供 CDS 和蛋白序列。非编码 RNA 不适用 CDS 或蛋白下载。真实 accession 的版本后缀予以保留。

cDNA

3 records

下载 cDNA FASTA

XR_009090866.1
TTTTCATGTTTTGCCCAAAATGAAATAAAAATTCAAAACTAGAAAAATCCAAAATCAAAAAGTCATCCCCTCTTCTTCCTCTTTCTTTCCACCAATTCACCTCTTTTTCTTCTTCCCACAATTCTGTGTCATCAGAAAATCCTTTAGATTTTTATTGAATTTTAAGAATACAGAAAACCCACATAAAATCGATGCCCGTAAATAGAAACCCTAGCTTCGGTGCGCGTGTGAATGTATAGGAAATTTGAATTGGGGTAATC...

XR_009090867.1
TTTTCATGTTTTGCCCAAAATGAAATAAAAATTCAAAACTAGAAAAATCCAAAATCAAAAAGTCATCCCCTCTTCTTCCTCTTTCTTTCCACCAATTCACCTCTTTTTCTTCTTCCCACAATTCTGTGTCATCAGAAAATCCTTTAGATTTTTATTGAATTTTAAGAATACAGAAAACCCACATAAAATCGATGCCCGTAAATAGAAACCCTAGCTTCGGTGCGCGTGTGAATGTATAGGAAATTTGAATTGGGGTAATC...

CDS

1 records

下载 CDS FASTA

LOC130990199
ATGACCTTGCTGATGGATAACAACAAAGATAATCCTTCCAGAGAGCGTGTTCAACAACTATTCAACAAGAATGTTGAGTTGGAGAACAAGCGAAGGAAAGCGGCGCAGGCAAGAATCCCTTCAGATCCTAACACATGGCAGAATATGCGTGAAAATTATGAAGCAATTCTCCTTGAAGACCATGCTTTTTCTGAACAACACGATATAGAATATGCTCTATGGCAATTGCATTATAGGAGGATTGAGGAGCTAAGGGCCCT...

Protein

1 records

下载 Protein FASTA

XP_057770407.1
MTLLMDNNKDNPSRERVQQLFNKNVELENKRRKAAQARIPSDPNTWQNMRENYEAILLEDHAFSEQHDIEYALWQLHYRRIEELRALFNAAALASAGSPASQNGKGTVRAGPDRLTKIRSQFKTFLSEATGFYHDLMLKIRSKYGLPLGYSSDDPENQIPMSKDGNKSSEGKKGLMSCHRCLIYLGDLARYKSLYGEGDSKARDFAAASSYYLQASSIWPSSGNPHHQLAILAGYSNDELLSIYRYFRSLAVDIPFVTAR...

上下游序列下载

upstream/downstream 最大各 10000 bp。负链基因会自动反向互补，使最终 FASTA 为转录方向 5′→3′。

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JBrowse

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