Gene Card 基因详情

支持统一新 ID、NCBI Gene ID、GeneID、locus_tag、Transcript ID、Protein ID，以及已人工核对的文献基因名查询。页面会先解析到丹参统一基因，再整合坐标、序列、注释、亚细胞定位、EMS 突变和下载入口。

当前解析结果

`SmilChr06G002347`

染色体: Chr06 坐标: 34156404-34159992 链方向: - 类型: protein_coding

基本信息

统一新 Gene ID	`SmilChr06G002347`
名称	SmilChr06G002347
描述	E3 ubiquitin-protein ligase BIG BROTHER-like
染色体 / SeqID	Chr06 / NC_080392.1
坐标与链方向	34156404 - 34159992 / `-`

ID 对照

NCBI Gene ID	`LOC130989168`
GeneID	`130989168`
locus_tag	`-`
NCBI Name	`LOC130989168`
原始查询	`SmilChr06G002347`

查看完整 ID 对照表

功能注释

来源	GFF basic annotation; NCBI GO GAF; Pfam-A/HMMER; Arabidopsis/Rice homolog
描述	E3 ubiquitin-protein ligase BIG BROTHER-like
产物	E3 ubiquitin-protein ligase BIG BROTHER-like
Arabidopsis	`AT3G47180` (AT3G47180) RING/U-box superfamily protein [Source:NCBI gene (formerly Entrezgene);Acc:823871] identity=53.3; qcov=0.517; evalue=1.02e-23; confidence=medium
Rice	`Os08g0548300` - identity=51.7; qcov=0.5; evalue=7.07e-25; confidence=medium
GO	GO:0004842 (ubiquitin-protein transferase activity); GO:0016567 (protein ubiquitination); GO:0031624 (ubiquitin conjugating enzyme binding); GO:0046621 (negative regulation of organ growth)
KEGG	-
Pfam	PF00097 (zf-C3HC4); PF12678 (zf-rbx1); PF13639 (zf-RING_2); PF13923 (zf-C3HC4_2); PF17123 (zf-RING_11)
InterPro	-
eggNOG	-
NR	GeneID:130989168

打开注释模块

亚细胞定位 Top 5

Rank	定位位置	中文	Score	Protein ID
1	Nucleus	细胞核	1.00000	`XP_057769089.1`
2	Cytosol	细胞质基质	1.00000	`XP_057769089.1`
3	Cytoplasm	细胞质	0.80000	`XP_057769089.1`
4	Chromosome	染色体	0.00000	`XP_057769089.1`
5	Centromere	着丝粒	0.00000	`XP_057769089.1`

进入亚细胞定位查询

EMS 诱变突变

下表显示该基因在丹参 EMS 材料中的前 12 个候选突变；完整结果可进入 EMS 突变库继续筛选或下载。

位置	REF	ALT	类型	影响	携带材料数	材料
`Chr6:34156572`	`T`	`TGG`	2bp_insertion	frameshift_variant	23	A20,A21,B110,B128,B132,B15,B4,B47,B48,B57,B60,B63,B68,B83,B86,B91,C20,C3,C34,C39,C43,C48,C77
`Chr6:34156911`	`G`	`A`	EMS_canonical_SNV	CDS_variant	2	C18,C37
`Chr6:34156912`	`G`	`A`	EMS_canonical_SNV	CDS_variant	4	B22,B30,C15,C25
`Chr6:34158601`	`G`	`A`	EMS_canonical_SNV	CDS_variant	1	A1

进入 EMS 突变库

预测功能结构域

结构域结果来自 Pfam-A HMM 数据库和 HMMER hmmscan；位置为对应蛋白序列上的氨基酸坐标。

XP_057769089.1

187 aa

187

zf-rbx1

zf-C3HC4_2

zf-RING_2

zf-RING_11

zf-C3HC4

PF12678 zf-rbx1 123-175 aa PF13923 zf-C3HC4_2 133-174 aa PF13639 zf-RING_2 133-175 aa PF17123 zf-RING_11 134-161 aa PF00097 zf-C3HC4 134-174 aa

XP_057769091.1

178 aa

178

zf-RING_2

zf-RING_11

zf-C3HC4

PF13639 zf-RING_2 133-169 aa PF17123 zf-RING_11 134-161 aa PF00097 zf-C3HC4 134-168 aa

Protein ID	来源	结构域编号	结构域名称	类型	起始 aa	终止 aa	E-value	Score	说明
`XP_057769089.1`	Pfam	`PF12678`	zf-rbx1	Domain	123	175	1.2e-09	39.0	RING-H2 zinc finger domain
`XP_057769089.1`	Pfam	`PF13923`	zf-C3HC4_2	Domain	133	174	3.3e-07	30.7	Zinc finger, C3HC4 type (RING finger)
`XP_057769089.1`	Pfam	`PF13639`	zf-RING_2	Domain	133	175	7.1e-14	52.5	Ring finger domain
`XP_057769089.1`	Pfam	`PF17123`	zf-RING_11	Domain	134	161	6.4e-07	29.7	RING-like zinc finger
`XP_057769089.1`	Pfam	`PF00097`	zf-C3HC4	Domain	134	174	1.1e-06	29.0	Zinc finger, C3HC4 type (RING finger)
`XP_057769091.1`	Pfam	`PF13639`	zf-RING_2	Domain	133	169	2.1e-10	41.4	Ring finger domain
`XP_057769091.1`	Pfam	`PF17123`	zf-RING_11	Domain	134	161	1e-06	29.1	RING-like zinc finger
`XP_057769091.1`	Pfam	`PF00097`	zf-C3HC4	Domain	134	168	3.3e-05	24.4	Zinc finger, C3HC4 type (RING finger)

cDNA / CDS / Protein 序列

下载基因组 DNA（仅基因区域）

每个公开基因均提供参考注释对应的转录本序列；蛋白编码基因另提供 CDS 和蛋白序列。非编码 RNA 不适用 CDS 或蛋白下载。真实 accession 的版本后缀予以保留。

cDNA

2 records

下载 cDNA FASTA

XM_057913106.1
TATATATAGTGTTGTGTATATGTATTACAGCAGAATAATTGCAGCTTTGATTTGAAGGGTGCCATGGACGAGGAACGAAGGAAAAGAACGAAAAGAACTACGTTGGATCAACTTGAAGAGGGAAGAGTTTTCCCGGTAGTGGTGGAAACTATAGAAAGCGCAGGCGACGAAGAGGGTGCTGAGACAAGTTCTTCTTCTGCTGCTGATGAAGATTTTGAATATAGCGATGATGAATTTTTATATGGTTCCATGAATTCTGG...

XM_057913108.1
TATATATAGTGTTGTGTATATGTATTACAGCAGAATAATTGCAGCTTTGATTTGAAGGGTGCCATGGACGAGGAACGAAGGAAAAGAACGAAAAGAACTACGTTGGATCAACTTGAAGAGGGAAGAGTTTTCCCGGTAGTGGTGGAAACTATAGAAAGCGCAGGCGACGAAGAGGGTGCTGAGACAAGTTCTTCTTCTGCTGCTGATGAAGATTTTGAATATAGCGATGATGAATTTTTATATGGTTCCATGAATTCTGG...

CDS

2 records

下载 CDS FASTA

LOC130989168
ATGGACGAGGAACGAAGGAAAAGAACGAAAAGAACTACGTTGGATCAACTTGAAGAGGGAAGAGTTTTCCCGGTAGTGGTGGAAACTATAGAAAGCGCAGGCGACGAAGAGGGTGCTGAGACAAGTTCTTCTTCTGCTGCTGATGAAGATTTTGAATATAGCGATGATGAATTTTTATATGGTTCCATGAATTCTGGAATAGATTTCTGGGAGGATGATAGCTATTCTGACGGGGGAATTGAAGAGGATGATGTTGATCC...

Protein

2 records

下载 Protein FASTA

XP_057769089.1
MDEERRKRTKRTTLDQLEEGRVFPVVVETIESAGDEEGAETSSSSAADEDFEYSDDEFLYGSMNSGIDFWEDDSYSDGGIEEDDVDPDQLSYEELIALGEMVGVENKGLSEDEISKYLRPLTCNSTSTLLIDRCVICQVEYEVGENLVSLQCHHLYHTDCISKWLQINKICPICNNEVRTETSPKDA

XP_057769091.1
MDEERRKRTKRTTLDQLEEGRVFPVVVETIESAGDEEGAETSSSSAADEDFEYSDDEFLYGSMNSGIDFWEDDSYSDGGIEEDDVDPDQLSYEELIALGEMVGVENKGLSEDEISKYLRPLTCNSTSTLLIDRCVICQVEYEVGENLVSLQCHHLYHTDCISKWLQINKFVFADLPDL

上下游序列下载

upstream/downstream 最大各 10000 bp。负链基因会自动反向互补，使最终 FASTA 为转录方向 5′→3′。

下载 upstream 下载 downstream 下载 upstream + gene + downstream

JBrowse

跳转到基因组浏览器