Gene Card 基因详情

支持统一新 ID、NCBI Gene ID、GeneID、locus_tag、Transcript ID、Protein ID，以及已人工核对的文献基因名查询。页面会先解析到丹参统一基因，再整合坐标、序列、注释、亚细胞定位、EMS 突变和下载入口。

当前解析结果

`SmilChr06G002885`

染色体: Chr06 坐标: 41677201-41679370 链方向: - 类型: protein_coding

基本信息

统一新 Gene ID	`SmilChr06G002885`
名称	SmilChr06G002885
描述	phosphatidylinositol 3,4,5-trisphosphate 3-phosphatase and protein-tyrosine-phosphatase PTEN1
染色体 / SeqID	Chr06 / NC_080392.1
坐标与链方向	41677201 - 41679370 / `-`

ID 对照

NCBI Gene ID	`LOC130989638`
GeneID	`130989638`
locus_tag	`-`
NCBI Name	`LOC130989638`
原始查询	`SmilChr06G002885`

查看完整 ID 对照表

功能注释

来源	GFF basic annotation; NCBI GO GAF; KEGG smil; Pfam-A/HMMER; Arabidopsis/Rice homolog
描述	phosphatidylinositol 3,4,5-trisphosphate 3-phosphatase and protein-tyrosine-phosphatase PTEN1
产物	phosphatidylinositol 3%2C4%2C5-trisphosphate 3-phosphatase and protein-tyrosine-phosphatase PTEN1
Arabidopsis	`AT5G39400` (PTEN1) Calcium/lipid-binding (CaLB) phosphatase [Source:NCBI gene (formerly Entrezgene);Acc:833936] identity=63.5; qcov=0.985; evalue=0; confidence=high
Rice	`Os12g0407500` (OsPP130) - identity=39.4; qcov=0.586; evalue=2.77e-48; confidence=medium
GO	GO:0004725 (protein tyrosine phosphatase activity); GO:0005829 (cytosol); GO:0016314 (phosphatidylinositol-3,4,5-trisphosphate 3-phosphatase activity); GO:0046856 (phosphatidylinositol dephosphorylation)
KEGG	smil00562 (Inositol phosphate metabolism - Salvia miltiorrhiza (redroot sage)); smil01100 (Metabolic pathways - Salvia miltiorrhiza (redroot sage)); smil04070 (Phosphatidylinositol signaling system - Salvia miltiorrhiza (redroot sage))
Pfam	PF10409 (PTEN_C2); PF13350 (Y_phosphatase3); PF22741 (PTP-NADK); PF22784 (PTP-SAK); PF22785 (Tc-R-P)
InterPro	-
eggNOG	-
NR	GeneID:130989638

打开注释模块

亚细胞定位 Top 5

Rank	定位位置	中文	Score	Protein ID
1	Cytoplasm	细胞质	1.00000	`XP_057769650.1`
2	Cytosol	细胞质基质	1.00000	`XP_057769650.1`
3	Nucleus	细胞核	0.00000	`XP_057769650.1`
4	Chromosome	染色体	0.00000	`XP_057769650.1`
5	Centromere	着丝粒	0.00000	`XP_057769650.1`

进入亚细胞定位查询

EMS 诱变突变

下表显示该基因在丹参 EMS 材料中的前 12 个候选突变；完整结果可进入 EMS 突变库继续筛选或下载。

位置	REF	ALT	类型	影响	携带材料数	材料
`Chr6:41677492`	`C`	`T`	EMS_canonical_SNV	CDS_variant	2	B140,C17
`Chr6:41677522`	`C`	`T`	EMS_canonical_SNV	CDS_variant	1	C73
`Chr6:41677624`	`C`	`T`	EMS_canonical_SNV	CDS_variant	2	B2,C33
`Chr6:41677982`	`C`	`T`	EMS_canonical_SNV	CDS_variant	1	B104
`Chr6:41678011`	`C`	`T`	EMS_canonical_SNV	CDS_variant	3	B50,C47,C7
`Chr6:41678155`	`G`	`A`	EMS_canonical_SNV	CDS_variant	2	B32,C23
`Chr6:41678207`	`C`	`T`	EMS_canonical_SNV	CDS_variant	3	B30,C15,C25
`Chr6:41678273`	`G`	`A`	EMS_canonical_SNV	CDS_variant	1	B78
`Chr6:41678710`	`G`	`A`	EMS_canonical_SNV	CDS_variant	4	B15,B27,B57,D7
`Chr6:41678739`	`C`	`T`	EMS_canonical_SNV	CDS_variant	1	B80
`Chr6:41678887`	`G`	`A`	EMS_canonical_SNV	CDS_variant	1	B91

进入 EMS 突变库

预测功能结构域

结构域结果来自 Pfam-A HMM 数据库和 HMMER hmmscan；位置为对应蛋白序列上的氨基酸坐标。

XP_057769650.1

411 aa

206

411

Tc-R-P

PTP-NADK

PTP-SAK

Y_phosphatase3

PTEN_C2

PF22785 Tc-R-P 104-173 aa PF22741 PTP-NADK 115-198 aa PF22784 PTP-SAK 117-181 aa PF13350 Y_phosphatase3 140-191 aa PF10409 PTEN_C2 321-398 aa

XP_057769651.1

411 aa

206

411

Tc-R-P

PTP-NADK

PTP-SAK

Y_phosphatase3

PTEN_C2

PF22785 Tc-R-P 104-173 aa PF22741 PTP-NADK 115-198 aa PF22784 PTP-SAK 117-181 aa PF13350 Y_phosphatase3 140-191 aa PF10409 PTEN_C2 321-398 aa

XP_057769652.1

411 aa

206

411

Tc-R-P

PTP-NADK

PTP-SAK

Y_phosphatase3

PTEN_C2

PF22785 Tc-R-P 104-173 aa PF22741 PTP-NADK 115-198 aa PF22784 PTP-SAK 117-181 aa PF13350 Y_phosphatase3 140-191 aa PF10409 PTEN_C2 321-398 aa

Protein ID	来源	结构域编号	结构域名称	类型	起始 aa	终止 aa	E-value	Score	说明
`XP_057769650.1`	Pfam	`PF22785`	Tc-R-P	Domain	104	173	6e-10	40.3	Polymorphic toxin system, DSP-PTPase phosphatase
`XP_057769650.1`	Pfam	`PF22741`	PTP-NADK	Domain	115	198	2.2e-07	31.2	DSP-PTPase phosphatase fused to NAD+ Kinase
`XP_057769650.1`	Pfam	`PF22784`	PTP-SAK	Domain	117	181	5.5e-10	40.2	Swiss Army Knife protein, DSP-PTPase phosphatase domain
`XP_057769650.1`	Pfam	`PF13350`	Y_phosphatase3	Domain	140	191	2.7e-05	25.0	Tyrosine phosphatase family
`XP_057769650.1`	Pfam	`PF10409`	PTEN_C2	Domain	321	398	9.6e-10	39.0	C2 domain of PTEN tumour-suppressor protein
`XP_057769651.1`	Pfam	`PF22785`	Tc-R-P	Domain	104	173	6e-10	40.3	Polymorphic toxin system, DSP-PTPase phosphatase
`XP_057769651.1`	Pfam	`PF22741`	PTP-NADK	Domain	115	198	2.2e-07	31.2	DSP-PTPase phosphatase fused to NAD+ Kinase
`XP_057769651.1`	Pfam	`PF22784`	PTP-SAK	Domain	117	181	5.5e-10	40.2	Swiss Army Knife protein, DSP-PTPase phosphatase domain
`XP_057769651.1`	Pfam	`PF13350`	Y_phosphatase3	Domain	140	191	2.7e-05	25.0	Tyrosine phosphatase family
`XP_057769651.1`	Pfam	`PF10409`	PTEN_C2	Domain	321	398	9.6e-10	39.0	C2 domain of PTEN tumour-suppressor protein
`XP_057769652.1`	Pfam	`PF22785`	Tc-R-P	Domain	104	173	6e-10	40.3	Polymorphic toxin system, DSP-PTPase phosphatase
`XP_057769652.1`	Pfam	`PF22741`	PTP-NADK	Domain	115	198	2.2e-07	31.2	DSP-PTPase phosphatase fused to NAD+ Kinase
`XP_057769652.1`	Pfam	`PF22784`	PTP-SAK	Domain	117	181	5.5e-10	40.2	Swiss Army Knife protein, DSP-PTPase phosphatase domain
`XP_057769652.1`	Pfam	`PF13350`	Y_phosphatase3	Domain	140	191	2.7e-05	25.0	Tyrosine phosphatase family
`XP_057769652.1`	Pfam	`PF10409`	PTEN_C2	Domain	321	398	9.6e-10	39.0	C2 domain of PTEN tumour-suppressor protein

cDNA / CDS / Protein 序列

下载基因组 DNA（仅基因区域）

每个公开基因均提供参考注释对应的转录本序列；蛋白编码基因另提供 CDS 和蛋白序列。非编码 RNA 不适用 CDS 或蛋白下载。真实 accession 的版本后缀予以保留。

cDNA

3 records

下载 cDNA FASTA

XM_057913668.1
TCTGAAGAAAAAAAAAACAGAGAGAATAGAGTAAATTAATTAGAGAAAAAATTCGTGGGACCCAAAACTGGACATGGGCTTCTTCATCATCTGTTTGATTTGGCCATCTTAAAGAAGAAGCATCATCAACACAGGACTGAATTTTTTCTCCTTACTTTCTCCATTCTTGGACCAATCTTGGTGATCTTCTTCGATTCACTTTGATTGTTCCAAGCTTATCCATCGCTTTCATAATTAACATGGTTGGTGCAGGCAAGTTT...

XM_057913669.1
TCTGAAGAAAAAAAAAACAGAGAGAATAGAGTAAATTAATTAGAGAAAAAATTCGTGGGACCCAAAACTGGACATGGGCTTCTTCATCATCTGTTTGATTTGGCCATCTTAAAGAAGAAGCATCATCAACACAGGACTGAATTTTTTCTCCTTACTTTCTCCATTCTTGGACCAATCTTGGTGATCTTCTTCGATTCACTTTGATTGTTCCAAGCTTATCCATCGCTTTCATAATTAACATGTACGAAATCCCACAATAT...

CDS

3 records

下载 CDS FASTA

LOC130989638
ATGGGGTTGAAGATGTCAAAGAAGGGGCAGAAAAGCCCCGAGAGCAGCATGAATGTCCGTTTTGTTCGGAGCCAGCTGGTGAGCTGCCTCTGGAAGAACTACATACGCAACCTCGTGTCGAAGAAGAGGCGGCGGCTGCTGGTGGACGGATACGATCTCGACATGACGTACATCACCGATCGCATCCTCGCGATGTCGTTCCCAGCGGAGCGCATGCGCGCCATGTACCGCAACCCTCTCTGGCAGGTGAAATCCGTGCT...

Protein

3 records

下载 Protein FASTA

XP_057769650.1
MGLKMSKKGQKSPESSMNVRFVRSQLVSCLWKNYIRNLVSKKRRRLLVDGYDLDMTYITDRILAMSFPAERMRAMYRNPLWQVKSVLEMKHRGHYKVYNLCIEEDYDPLHFNGCVERFPFDDNHVPPLSMVKDFCQDVHSWLATDPKNIAVVHCMAGKGRTGLMVSCYLVYTGMPAEKALHLYAERRTTNNEGVSIASQRRYVAYWEKTLSHSNTLDLASSPYVNLPQPCTRELQHIRLYDAANISQVFVVVSELQEIAE...

XP_057769651.1
MGLKMSKKGQKSPESSMNVRFVRSQLVSCLWKNYIRNLVSKKRRRLLVDGYDLDMTYITDRILAMSFPAERMRAMYRNPLWQVKSVLEMKHRGHYKVYNLCIEEDYDPLHFNGCVERFPFDDNHVPPLSMVKDFCQDVHSWLATDPKNIAVVHCMAGKGRTGLMVSCYLVYTGMPAEKALHLYAERRTTNNEGVSIASQRRYVAYWEKTLSHSNTLDLASSPYVNLPQPCTRELQHIRLYDAANISQVFVVVSELQEIAE...

上下游序列下载

upstream/downstream 最大各 10000 bp。负链基因会自动反向互补，使最终 FASTA 为转录方向 5′→3′。

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