Gene Card 基因详情

支持统一新 ID、NCBI Gene ID、GeneID、locus_tag、Transcript ID、Protein ID，以及已人工核对的文献基因名查询。页面会先解析到丹参统一基因，再整合坐标、序列、注释、亚细胞定位、EMS 突变和下载入口。

当前解析结果

`SmilChr06G003057`

染色体: Chr06 坐标: 43459414-43462631 链方向: + 类型: protein_coding

基本信息

统一新 Gene ID	`SmilChr06G003057`
名称	SmilChr06G003057
描述	6-phosphogluconate dehydrogenase, decarboxylating 1
染色体 / SeqID	Chr06 / NC_080392.1
坐标与链方向	43459414 - 43462631 / `+`

ID 对照

NCBI Gene ID	`LOC130989779`
GeneID	`130989779`
locus_tag	`-`
NCBI Name	`LOC130989779`
原始查询	`SmilChr06G003057`

查看完整 ID 对照表

功能注释

来源	GFF basic annotation; NCBI GO GAF; KEGG smil; Pfam-A/HMMER; Arabidopsis/Rice homolog
描述	6-phosphogluconate dehydrogenase, decarboxylating 1
产物	6-phosphogluconate dehydrogenase%2C decarboxylating 1
Arabidopsis	`AT3G02360` (AT3G02360) 6-phosphogluconate dehydrogenase family protein [Source:NCBI gene (formerly Entrezgene);Acc:821163] identity=86.6; qcov=0.984; evalue=0; confidence=high
Rice	`Os06g0111500` (Os6PGDH1) - identity=86.3; qcov=0.977; evalue=0; confidence=high
GO	GO:0004616 (phosphogluconate dehydrogenase (decarboxylating) activity); GO:0005829 (cytosol); GO:0006098 (pentose-phosphate shunt); GO:0009051 (pentose-phosphate shunt, oxidative branch); GO:0046177 (GO:0046177); GO:0050661 (NADP binding)
KEGG	smil00030 (Pentose phosphate pathway - Salvia miltiorrhiza (redroot sage)); smil00480 (Glutathione metabolism - Salvia miltiorrhiza (redroot sage)); smil01100 (Metabolic pathways - Salvia miltiorrhiza (redroot sage)); smil01110 (Biosynthesis of secondary metabolites - Salvia miltiorrhiza (redroot sage)); smil01200 (Carbon metabolism - Salvia miltiorrhiza (redroot sage))
Pfam	PF00393 (6PGD); PF03446 (NAD_binding_2)
InterPro	-
eggNOG	-
NR	GeneID:130989779

打开注释模块

亚细胞定位 Top 5

Rank	定位位置	中文	Score	Protein ID
1	Cytoplasm	细胞质	1.00000	`XP_057769862.1`
2	Cytosol	细胞质基质	1.00000	`XP_057769862.1`
3	Nucleus	细胞核	0.00000	`XP_057769862.1`
4	Chromosome	染色体	0.00000	`XP_057769862.1`
5	Centromere	着丝粒	0.00000	`XP_057769862.1`

进入亚细胞定位查询

EMS 诱变突变

下表显示该基因在丹参 EMS 材料中的前 12 个候选突变；完整结果可进入 EMS 突变库继续筛选或下载。

位置	REF	ALT	类型	影响	携带材料数	材料
`Chr6:43460973`	`G`	`A`	EMS_canonical_SNV	CDS_variant	1	D10
`Chr6:43461210`	`G`	`A`	EMS_canonical_SNV	CDS_variant	3	B125,B23,C87
`Chr6:43461289`	`G`	`A`	EMS_canonical_SNV	CDS_variant	3	B125,B23,C87
`Chr6:43461412`	`G`	`A`	EMS_canonical_SNV	CDS_variant	2	B97,C83
`Chr6:43461438`	`C`	`T`	EMS_canonical_SNV	CDS_variant	1	A18
`Chr6:43461480`	`C`	`T`	EMS_canonical_SNV	CDS_variant	2	B77,B8
`Chr6:43461519`	`C`	`T`	EMS_canonical_SNV	CDS_variant	1	B28
`Chr6:43461726`	`C`	`T`	EMS_canonical_SNV	CDS_variant	4	B13,B49,B71,C31
`Chr6:43462359`	`C`	`T`	EMS_canonical_SNV	CDS_variant	1	D10
`Chr6:43462374`	`C`	`T`	EMS_canonical_SNV	CDS_variant	2	B49,C24

进入 EMS 突变库

预测功能结构域

结构域结果来自 Pfam-A HMM 数据库和 HMMER hmmscan；位置为对应蛋白序列上的氨基酸坐标。

XP_057769862.1

486 aa

243

486

NAD_binding_2

6PGD

PF03446 NAD_binding_2 10-182 aa PF00393 6PGD 187-477 aa

XP_057769863.1

486 aa

243

486

NAD_binding_2

6PGD

PF03446 NAD_binding_2 10-182 aa PF00393 6PGD 187-477 aa

Protein ID	来源	结构域编号	结构域名称	类型	起始 aa	终止 aa	E-value	Score	说明
`XP_057769862.1`	Pfam	`PF03446`	NAD_binding_2	Domain	10	182	4.6e-46	157.5	NAD binding domain of 6-phosphogluconate dehydrogenase
`XP_057769862.1`	Pfam	`PF00393`	6PGD	Domain	187	477	2.6e-126	421.6	6-phosphogluconate dehydrogenase, C-terminal domain
`XP_057769863.1`	Pfam	`PF03446`	NAD_binding_2	Domain	10	182	4.6e-46	157.5	NAD binding domain of 6-phosphogluconate dehydrogenase
`XP_057769863.1`	Pfam	`PF00393`	6PGD	Domain	187	477	2.6e-126	421.6	6-phosphogluconate dehydrogenase, C-terminal domain

cDNA / CDS / Protein 序列

下载基因组 DNA（仅基因区域）

每个公开基因均提供参考注释对应的转录本序列；蛋白编码基因另提供 CDS 和蛋白序列。非编码 RNA 不适用 CDS 或蛋白下载。真实 accession 的版本后缀予以保留。

cDNA

2 records

下载 cDNA FASTA

XM_057913880.1
ACATTGCTAGAGTTTCCCAAAATAACCCCCGCCCACCACAAAATAATTACTACCAGAAAAAGTAAACAAAACCAAACATAAAAAAAAATCAAATTTTTGCAGTAAATCGACTGTCTGAATCAAAATTCACCTCCATCCCAGTTGTTAATTTATAAAAAGATGAGCTCTTGTCTTAGCTATTGTTCCAAAAATAAAAGGATTTGTAGAATTTTAATGGAATAATAAACTTAATAAAAAATAAAAAAAGAAGATCTCCCACC...

XM_057913879.1
AGGTAGTTGGCCGAATTTGACCCGCATCAGTTCACAGGCGTTCAACATTTTTATCTTTGTTGTGCAGCTACACCCATTGGTTTCGCTCTTGCCTAGTCAAATTCAGTTGTAGCAGAAAAGCAAAAGGAGAAAGGATGGCTGAGAAATCTTCAAAACTGACCAGAATAGGCCTTGCTGGCCTTGCTGTTATGGGACAAAACTTGGCCCTCAACATTGCGGAGAAAGGCTTTCCGATTTCTGTCTACAATCGGACTACATCT...

CDS

2 records

下载 CDS FASTA

LOC130989779
ATGGCTGAGAAATCTTCAAAACTGACCAGAATAGGCCTTGCTGGCCTTGCTGTTATGGGACAAAACTTGGCCCTCAACATTGCGGAGAAAGGCTTTCCGATTTCTGTCTACAATCGGACTACATCTAAAGTTGATGAGACTATTGAAAGAGCAAAAGTGGAAGGAAATCTTCCGGTGTTTGGCTTCCATGATCCCGAATCATTTGTCAACTCGATCCAAAAACCTCGTGTGATCATCATGCTTGTCAAGGCTGGGGCTCC...

Protein

2 records

下载 Protein FASTA

XP_057769862.1
MAEKSSKLTRIGLAGLAVMGQNLALNIAEKGFPISVYNRTTSKVDETIERAKVEGNLPVFGFHDPESFVNSIQKPRVIIMLVKAGAPVDQTIKTLSAYMEKGDCIIDGGNEWYENTERREKAMAELGLLYLGMGVSGGEEGARNGPSMMPGGSIEAYKYIEDIVLKVAAQVPDSGPCVTYIGKGGSGNFVKMIHNGIEYGDMQLISEAYDVLKSVGKLSNEELKKVFTEWNNGELQSFLIEITADIFGIKDDKGDGYLVD...

XP_057769863.1
MAEKSSKLTRIGLAGLAVMGQNLALNIAEKGFPISVYNRTTSKVDETIERAKVEGNLPVFGFHDPESFVNSIQKPRVIIMLVKAGAPVDQTIKTLSAYMEKGDCIIDGGNEWYENTERREKAMAELGLLYLGMGVSGGEEGARNGPSMMPGGSIEAYKYIEDIVLKVAAQVPDSGPCVTYIGKGGSGNFVKMIHNGIEYGDMQLISEAYDVLKSVGKLSNEELKKVFTEWNNGELQSFLIEITADIFGIKDDKGDGYLVD...

上下游序列下载

upstream/downstream 最大各 10000 bp。负链基因会自动反向互补，使最终 FASTA 为转录方向 5′→3′。

下载 upstream 下载 downstream 下载 upstream + gene + downstream

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