Gene Card 基因详情

支持统一新 ID、NCBI Gene ID、GeneID、locus_tag、Transcript ID、Protein ID，以及已人工核对的文献基因名查询。页面会先解析到丹参统一基因，再整合坐标、序列、注释、亚细胞定位、EMS 突变和下载入口。

当前解析结果

`SmilChr06G003284`

染色体: Chr06 坐标: 45379598-45392987 链方向: - 类型: protein_coding

基本信息

统一新 Gene ID	`SmilChr06G003284`
名称	SmilChr06G003284
描述	DNA polymerase delta catalytic subunit
染色体 / SeqID	Chr06 / NC_080392.1
坐标与链方向	45379598 - 45392987 / `-`

ID 对照

NCBI Gene ID	`LOC130989997`
GeneID	`130989997`
locus_tag	`-`
NCBI Name	`LOC130989997`
原始查询	`SmilChr06G003284`

查看完整 ID 对照表

功能注释

来源	GFF basic annotation; NCBI GO GAF; KEGG smil; Pfam-A/HMMER; Arabidopsis/Rice homolog
描述	DNA polymerase delta catalytic subunit
产物	DNA polymerase delta catalytic subunit
Arabidopsis	`AT5G63960` (AT5G63960) DNA polymerase delta subunit 1 [Source:NCBI gene (formerly Entrezgene);Acc:836517] identity=82.4; qcov=0.992; evalue=0; confidence=high
Rice	`Os11g0186400` (OsPoldelta1) - identity=84.9; qcov=0.978; evalue=0; confidence=high
GO	GO:0000166 (nucleotide binding); GO:0003677 (DNA binding); GO:0003887 (DNA-directed DNA polymerase activity); GO:0006261 (DNA-templated DNA replication); GO:0006287 (base-excision repair, gap-filling); GO:0006297 (nucleotide-excision repair, DNA gap filling); GO:0008296 (3'-5'-DNA exonuclease activity); GO:0043625 (delta DNA polymerase complex); GO:0045004 (DNA replication proofreading)
KEGG	smil03030 (DNA replication - Salvia miltiorrhiza (redroot sage)); smil03410 (Base excision repair - Salvia miltiorrhiza (redroot sage)); smil03420 (Nucleotide excision repair - Salvia miltiorrhiza (redroot sage)); smil03430 (Mismatch repair - Salvia miltiorrhiza (redroot sage)); smil03440 (Homologous recombination - Salvia miltiorrhiza (redroot sage))
Pfam	PF00136 (DNA_pol_B); PF03104 (DNA_pol_B_exo1); PF14260 (zf-C4pol); PF24055 (POL3_N)
InterPro	-
eggNOG	-
NR	GeneID:130989997

打开注释模块

亚细胞定位 Top 5

Rank	定位位置	中文	Score	Protein ID
1	Nucleus	细胞核	1.00000	`XP_057770162.1`
2	Nucleoplasm	核质	0.80000	`XP_057770162.1`
3	Cytoplasm	细胞质	0.60000	`XP_057770162.1`
4	Cytosol	细胞质基质	0.60000	`XP_057770162.1`
5	Chromosome	染色体	0.00000	`XP_057770162.1`

进入亚细胞定位查询

EMS 诱变突变

下表显示该基因在丹参 EMS 材料中的前 12 个候选突变；完整结果可进入 EMS 突变库继续筛选或下载。

位置	REF	ALT	类型	影响	携带材料数	材料
`Chr6:45380338`	`C`	`T`	EMS_canonical_SNV	CDS_variant	2	B80,C29
`Chr6:45380344`	`C`	`T`	EMS_canonical_SNV	CDS_variant	1	C11
`Chr6:45381566`	`G`	`A`	EMS_canonical_SNV	CDS_variant	1	C83
`Chr6:45382490`	`C`	`T`	EMS_canonical_SNV	CDS_variant	2	B10,B114
`Chr6:45382493`	`G`	`A`	EMS_canonical_SNV	CDS_variant	2	B10,B114
`Chr6:45382559`	`G`	`A`	EMS_canonical_SNV	CDS_variant	1	C15
`Chr6:45382562`	`C`	`T`	EMS_canonical_SNV	CDS_variant	2	C78,C9
`Chr6:45383418`	`C`	`T`	EMS_canonical_SNV	CDS_variant	1	C44
`Chr6:45383442`	`C`	`T`	EMS_canonical_SNV	CDS_variant	1	B80
`Chr6:45384560`	`G`	`A`	EMS_canonical_SNV	CDS_variant	2	A6,B45
`Chr6:45384572`	`C`	`T`	EMS_canonical_SNV	CDS_variant	2	A6,B45
`Chr6:45384574`	`AGC`	`A`	2bp_deletion	frameshift_variant	2	A6,B45

进入 EMS 突变库

预测功能结构域

结构域结果来自 Pfam-A HMM 数据库和 HMMER hmmscan；位置为对应蛋白序列上的氨基酸坐标。

XP_057770162.1

1084 aa

542

1084

POL3_N

DNA_pol_B_exo1

DNA_pol_B

zf-C4pol

PF24055 POL3_N 127-202 aa PF03104 DNA_pol_B_exo1 225-458 aa PF00136 DNA_pol_B 522-957 aa PF14260 zf-C4pol 994-1065 aa

Protein ID	来源	结构域编号	结构域名称	类型	起始 aa	终止 aa	E-value	Score	说明
`XP_057770162.1`	Pfam	`PF24055`	POL3_N	Domain	127	202	3.7e-08	34.5	DNA polymerase delta catalytic subunit-like, N-terminal domain
`XP_057770162.1`	Pfam	`PF03104`	DNA_pol_B_exo1	Family	225	458	1.4e-71	241.5	DNA polymerase family B, exonuclease domain
`XP_057770162.1`	Pfam	`PF00136`	DNA_pol_B	Family	522	957	2.3e-161	538.3	DNA polymerase family B
`XP_057770162.1`	Pfam	`PF14260`	zf-C4pol	Domain	994	1065	6.5e-19	68.7	C4-type zinc-finger of DNA polymerase delta

cDNA / CDS / Protein 序列

下载基因组 DNA（仅基因区域）

每个公开基因均提供参考注释对应的转录本序列；蛋白编码基因另提供 CDS 和蛋白序列。非编码 RNA 不适用 CDS 或蛋白下载。真实 accession 的版本后缀予以保留。

cDNA

1 records

下载 cDNA FASTA

XM_057914179.1
ATGAGCGCCACCGGCAACACTAGGAAGCGGGGGCCGCCGCCGCCATCAGCAACTCCATCTCCTCAACTGAAGCACCGGGCAATAGTGGAGGATGAGGAGTTGGACGAGGACGTATTCCTCGAGGAAACCCTACTACAGTACGAGGAGGAGGACTCGCAGCGCCGTGCGCTCGCCGACCGTCTCGTCAAGTGGAAGCGTCCGCTGCTTTCCCACGCCTACCAGTCTCAGTCTCAAAACATCGTTTTTCAACAATTGGAGAT...

CDS

1 records

下载 CDS FASTA

LOC130989997
ATGAGCGCCACCGGCAACACTAGGAAGCGGGGGCCGCCGCCGCCATCAGCAACTCCATCTCCTCAACTGAAGCACCGGGCAATAGTGGAGGATGAGGAGTTGGACGAGGACGTATTCCTCGAGGAAACCCTACTACAGTACGAGGAGGAGGACTCGCAGCGCCGTGCGCTCGCCGACCGTCTCGTCAAGTGGAAGCGTCCGCTGCTTTCCCACGCCTACCAGTCTCAGTCTCAAAACATCGTTTTTCAACAATTGGAGAT...

Protein

1 records

下载 Protein FASTA

XP_057770162.1
MSATGNTRKRGPPPPSATPSPQLKHRAIVEDEELDEDVFLEETLLQYEEEDSQRRALADRLVKWKRPLLSHAYQSQSQNIVFQQLEIDYIIGDSNRELLPSSTGPAAIIRIFGVTKEGHSVCCNVHGFEPYFYISCPPGMGPDDISRFHQVLEGRMREANRNSKVPKFVRRIELVQRRSIMYYQQQNAHPFLKIVVALPTMVASCRGILDRGVQIDGLGMKSFMTYESNVLFALRFMIDCNIVGGNWIEVPHGKYKKAGK...

上下游序列下载

upstream/downstream 最大各 10000 bp。负链基因会自动反向互补，使最终 FASTA 为转录方向 5′→3′。

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JBrowse

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