Gene Card 基因详情

支持统一新 ID、NCBI Gene ID、GeneID、locus_tag、Transcript ID、Protein ID，以及已人工核对的文献基因名查询。页面会先解析到丹参统一基因，再整合坐标、序列、注释、亚细胞定位、EMS 突变和下载入口。

当前解析结果

`SmilChr07G000074`

染色体: Chr07 坐标: 348194-354599 链方向: + 类型: protein_coding

基本信息

统一新 Gene ID	`SmilChr07G000074`
名称	SmilChr07G000074
描述	DNA repair protein RAD5B
染色体 / SeqID	Chr07 / NC_080393.1
坐标与链方向	348194 - 354599 / `+`

ID 对照

NCBI Gene ID	`LOC130991267`
GeneID	`130991267`
locus_tag	`-`
NCBI Name	`LOC130991267`
原始查询	`SmilChr07G000074`

查看完整 ID 对照表

功能注释

来源	GFF basic annotation; NCBI GO GAF; Pfam-A/HMMER; Arabidopsis/Rice homolog
描述	DNA repair protein RAD5B
产物	DNA repair protein RAD5B
Arabidopsis	`AT5G43530` (AT5G43530) Helicase protein with RING/U-box domain-containing protein [Source:NCBI gene (formerly Entrezgene);Acc:834373] identity=70.6; qcov=0.981; evalue=0; confidence=high
Rice	`Os02g0527100` - identity=57.8; qcov=0.879; evalue=0; confidence=high
GO	GO:0003676 (nucleic acid binding); GO:0005524 (ATP binding); GO:0008270 (zinc ion binding); GO:0016818 (hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides); GO:0140658 (ATP-dependent chromatin remodeler activity)
KEGG	-
Pfam	PF00097 (zf-C3HC4); PF00176 (SNF2-rel_dom); PF00270 (DEAD); PF00271 (Helicase_C); PF04851 (ResIII); PF08797 (HIRAN); PF13445 (zf-RING_UBOX); PF13639 (zf-RING_2); PF13920 (zf-C3HC4_3); PF13923 (zf-C3HC4_2)
InterPro	-
eggNOG	-
NR	GeneID:130991267

打开注释模块

亚细胞定位 Top 5

Rank	定位位置	中文	Score	Protein ID
1	Nucleus	细胞核	1.00000	`XP_057771357.1`
2	Chromosome	染色体	0.00000	`XP_057771357.1`
3	Centromere	着丝粒	0.00000	`XP_057771357.1`
4	Chromatin	染色质	0.00000	`XP_057771357.1`
5	Telomere	端粒	0.00000	`XP_057771357.1`

进入亚细胞定位查询

EMS 诱变突变

下表显示该基因在丹参 EMS 材料中的前 12 个候选突变；完整结果可进入 EMS 突变库继续筛选或下载。

位置	REF	ALT	类型	影响	携带材料数	材料
`Chr7:349039`	`C`	`T`	EMS_canonical_SNV	CDS_variant	3	C38,C4,C65
`Chr7:349073`	`C`	`T`	EMS_canonical_SNV	CDS_variant	3	B64,C46,D11
`Chr7:349118`	`C`	`T`	EMS_canonical_SNV	CDS_variant	2	A10,B117
`Chr7:349173`	`G`	`A`	EMS_canonical_SNV	CDS_variant	1	C29
`Chr7:349209`	`G`	`A`	EMS_canonical_SNV	CDS_variant	1	B76
`Chr7:349993`	`C`	`T`	EMS_canonical_SNV	CDS_variant	1	C65
`Chr7:350667`	`G`	`A`	EMS_canonical_SNV	CDS_variant	1	D11
`Chr7:351304`	`AC`	`A`	1bp_deletion	frameshift_variant	127	A1,A10,A15,A16,A19,A22,A25,A3,A4,A5,A6,A9,B1,B100,B104,B107,B11,B110,B111,B112,B114,B119,B120,B122,B123,B125,B126,B127,B128,B132,B133,B137,B139,B14,B15,B16,B17,B21,B23,B25,B27,B30,B32,B37,B4,B40,B41,B42,B43,B45,B48,B49,B5,B50,B53,B55,B60,B64,B67,B69,B70,B73,B75,B76,B77,B79,B8,B85,B86,B87,B88,B89,B9,B90,B91,B92,B94,B95,C1,C10,C11,C14,C16,C18,C19,C21,C22,C23,C24,C26,C27,C29,C3,C30,C31,C33,C34,C37,C38,C4,C42,C43,C44,C45,C51,C52,C53,C54,C56,C57,C58,C6,C61,C65,C69,C70,C72,C73,C75,C76,C77,C81,C9,D2,D5,D8,D9
`Chr7:351331`	`G`	`A`	EMS_canonical_SNV	CDS_variant	1	D11
`Chr7:351438`	`C`	`T`	EMS_canonical_SNV	CDS_variant	3	B39,C48,D4
`Chr7:352197`	`C`	`T`	EMS_canonical_SNV	CDS_variant	4	B38,B39,C48,D4
`Chr7:352483`	`GAA`	`G`	2bp_deletion	frameshift_variant	1	B112

进入 EMS 突变库

预测功能结构域

结构域结果来自 Pfam-A HMM 数据库和 HMMER hmmscan；位置为对应蛋白序列上的氨基酸坐标。

XP_057771357.1

927 aa

464

927

HIRAN

ResIII

SNF2-rel_dom

DEAD

zf-C3HC4_3

zf-C3HC4_2

zf-RING_2

zf-RING_UBOX

zf-C3HC4

Helicase_C

PF08797 HIRAN 40-144 aa PF04851 ResIII 267-503 aa PF00176 SNF2-rel_dom 271-636 aa PF00270 DEAD 340-480 aa PF13920 zf-C3HC4_3 687-735 aa PF13923 zf-C3HC4_2 689-729 aa PF13639 zf-RING_2 689-730 aa PF13445 zf-RING_UBOX 690-727 aa PF00097 zf-C3HC4 690-729 aa PF00271 Helicase_C 760-874 aa

Protein ID	来源	结构域编号	结构域名称	类型	起始 aa	终止 aa	E-value	Score	说明
`XP_057771357.1`	Pfam	`PF08797`	HIRAN	Domain	40	144	2.2e-12	47.4	HIRAN domain
`XP_057771357.1`	Pfam	`PF04851`	ResIII	Family	267	503	8.5e-07	29.7	Type III restriction enzyme, res subunit
`XP_057771357.1`	Pfam	`PF00176`	SNF2-rel_dom	Domain	271	636	2e-73	247.7	SNF2-related domain
`XP_057771357.1`	Pfam	`PF00270`	DEAD	Domain	340	480	2.4e-07	31.3	DEAD/DEAH box helicase
`XP_057771357.1`	Pfam	`PF13920`	zf-C3HC4_3	Domain	687	735	5.6e-10	39.6	Zinc finger, C3HC4 type (RING finger)
`XP_057771357.1`	Pfam	`PF13923`	zf-C3HC4_2	Domain	689	729	1.1e-06	29.0	Zinc finger, C3HC4 type (RING finger)
`XP_057771357.1`	Pfam	`PF13639`	zf-RING_2	Domain	689	730	1e-07	32.8	Ring finger domain
`XP_057771357.1`	Pfam	`PF13445`	zf-RING_UBOX	Domain	690	727	5.5e-07	30.2	RING-type zinc-finger
`XP_057771357.1`	Pfam	`PF00097`	zf-C3HC4	Domain	690	729	4.7e-09	36.7	Zinc finger, C3HC4 type (RING finger)
`XP_057771357.1`	Pfam	`PF00271`	Helicase_C	Domain	760	874	4.4e-22	79.1	Helicase conserved C-terminal domain

cDNA / CDS / Protein 序列

下载基因组 DNA（仅基因区域）

每个公开基因均提供参考注释对应的转录本序列；蛋白编码基因另提供 CDS 和蛋白序列。非编码 RNA 不适用 CDS 或蛋白下载。真实 accession 的版本后缀予以保留。

cDNA

1 records

下载 cDNA FASTA

XM_057915374.1
ATTGAGCCGATGGGGACTGTGAGGGTGAAAGAGGAAATTGATGTGGGTTTTGTAGAGGCTGAGTTTTCAGCAGAGGAAAAGAGAGATTTGAGTGGTGAAAAAAGAGAAGAGGAAAAGCAAGAGATCGTTAATGGAGCTGAGGCTGAAACTACGGTGGAAGCTGTGAGGGTGAAAGAGGAAATTGATGTAGATTTTGCGGAGGCTGAGTTTTCAGCAGAGGAAAAGAGAGATTTGAGTGGTGAAAAAAGAGAAGAGGAAAA...

CDS

1 records

下载 CDS FASTA

LOC130991267
ATGCAATTGGCGCGTAATGGACGTAATGCTAAAAGAGCGAGGCCTGCGGAGAATGCCTTAAGTGCGGTGGTGATTGAGGATGGTGATTTTCCGGAGGAGCCGGGCTGGATGTTGGTGGGGAGGACAGTGGTTACGGGGATCTCAACGACAAAGGGCAGGAAATTGGAGAATAATGAGATTGTGCATTTTGCCTTTCCAGGTCCTAACACAAGAACTAAGATTAGCACCCATTTTATGAGTTCAAAGGCTGCTAATGCTGC...

Protein

1 records

下载 Protein FASTA

XP_057771357.1
MQLARNGRNAKRARPAENALSAVVIEDGDFPEEPGWMLVGRTVVTGISTTKGRKLENNEIVHFAFPGPNTRTKISTHFMSSKAANAASSIVRFSTKRYGEIGRLPMEWAKCLIPLVNSSKVKVLGRCVAAPVNLCMMQEIMLYVSFYIHETVFSEVDKSWKLEATNIDATIYPLLKLFELLKVRPFQKAQFTPEELDSRKRLLQLDDDSDNTASLLPSLKIRRASQDHKIHENHEQVISESSLNRLVGAVDTYNLEEMEP...

上下游序列下载

upstream/downstream 最大各 10000 bp。负链基因会自动反向互补，使最终 FASTA 为转录方向 5′→3′。

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