Gene Card 基因详情

支持统一新 ID、NCBI Gene ID、GeneID、locus_tag、Transcript ID、Protein ID，以及已人工核对的文献基因名查询。页面会先解析到丹参统一基因，再整合坐标、序列、注释、亚细胞定位、EMS 突变和下载入口。

当前解析结果

`SmilChr07G000579`

染色体: Chr07 坐标: 3930935-3935081 链方向: - 类型: protein_coding

基本信息

统一新 Gene ID	`SmilChr07G000579`
名称	SmilChr07G000579
描述	lipoamide acyltransferase component of branched-chain alpha-keto acid dehydrogenase complex, mitochondrial
染色体 / SeqID	Chr07 / NC_080393.1
坐标与链方向	3930935 - 3935081 / `-`

ID 对照

NCBI Gene ID	`LOC130991750`
GeneID	`130991750`
locus_tag	`-`
NCBI Name	`LOC130991750`
原始查询	`SmilChr07G000579`

查看完整 ID 对照表

功能注释

来源	GFF basic annotation; NCBI GO GAF; KEGG smil; Pfam-A/HMMER; Arabidopsis/Rice homolog
描述	lipoamide acyltransferase component of branched-chain alpha-keto acid dehydrogenase complex, mitochondrial
产物	lipoamide acyltransferase component of branched-chain alpha-keto acid dehydrogenase complex%2C mitochondrial
Arabidopsis	`AT3G06850` (BCE2) 2-oxoacid dehydrogenases acyltransferase family protein [Source:NCBI gene (formerly Entrezgene);Acc:819869] identity=53.8; qcov=1.01; evalue=0; confidence=high
Rice	`Os01g0314100` - identity=64.3; qcov=0.82; evalue=0; confidence=high
GO	GO:0005737 (cytoplasm); GO:0005739 (mitochondrion); GO:0016407 (acetyltransferase activity); GO:0031405 (lipoic acid binding)
KEGG	smil00280 (Valine, leucine and isoleucine degradation - Salvia miltiorrhiza (redroot sage)); smil00640 (Propanoate metabolism - Salvia miltiorrhiza (redroot sage)); smil00785 (Lipoic acid metabolism - Salvia miltiorrhiza (redroot sage)); smil01100 (Metabolic pathways - Salvia miltiorrhiza (redroot sage)); smil01110 (Biosynthesis of secondary metabolites - Salvia miltiorrhiza (redroot sage)); smil01210 (2-Oxocarboxylic acid metabolism - Salvia miltiorrhiza (redroot sage))
Pfam	PF00198 (2-oxoacid_dh); PF00364 (Biotin_lipoyl); PF02817 (E3_binding)
InterPro	-
eggNOG	-
NR	GeneID:130991750

打开注释模块

亚细胞定位 Top 5

Rank	定位位置	中文	Score	Protein ID
1	Mitochondrion	线粒体	1.00000	`XP_057772113.1`
2	Mitochondrion matrix	线粒体基质	0.60000	`XP_057772113.1`
3	Nucleus	细胞核	0.00000	`XP_057772113.1`
4	Chromosome	染色体	0.00000	`XP_057772113.1`
5	Centromere	着丝粒	0.00000	`XP_057772113.1`

进入亚细胞定位查询

EMS 诱变突变

下表显示该基因在丹参 EMS 材料中的前 12 个候选突变；完整结果可进入 EMS 突变库继续筛选或下载。

位置	REF	ALT	类型	影响	携带材料数	材料
`Chr7:3931267`	`C`	`T`	EMS_canonical_SNV	CDS_variant	1	C84
`Chr7:3931291`	`C`	`T`	EMS_canonical_SNV	CDS_variant	3	B86,C26,C39
`Chr7:3931296`	`C`	`T`	EMS_canonical_SNV	CDS_variant	1	C46
`Chr7:3931676`	`G`	`A`	EMS_canonical_SNV	CDS_variant	3	B33,B53,D10
`Chr7:3931796`	`C`	`T`	EMS_canonical_SNV	CDS_variant	5	A20,B133,B18,B89,C57
`Chr7:3931811`	`G`	`A`	EMS_canonical_SNV	CDS_variant	1	C17
`Chr7:3931857`	`G`	`A`	EMS_canonical_SNV	CDS_variant	2	B65,D6
`Chr7:3932096`	`G`	`A`	EMS_canonical_SNV	CDS_variant	2	B41,C10
`Chr7:3932318`	`G`	`A`	EMS_canonical_SNV	CDS_variant	1	B2
`Chr7:3932399`	`G`	`A`	EMS_canonical_SNV	CDS_variant	5	B34,B80,C13,C34,C56
`Chr7:3933056`	`G`	`A`	EMS_canonical_SNV	CDS_variant	1	B1
`Chr7:3933079`	`G`	`A`	EMS_canonical_SNV	CDS_variant	3	B60,B77,C6

进入 EMS 突变库

预测功能结构域

结构域结果来自 Pfam-A HMM 数据库和 HMMER hmmscan；位置为对应蛋白序列上的氨基酸坐标。

XP_057772113.1

523 aa

262

523

Biotin_lipoyl

E3_binding

2-oxoacid_dh

PF00364 Biotin_lipoyl 99-170 aa PF02817 E3_binding 213-248 aa PF00198 2-oxoacid_dh 291-520 aa

Protein ID	来源	结构域编号	结构域名称	类型	起始 aa	终止 aa	E-value	Score	说明
`XP_057772113.1`	Pfam	`PF00364`	Biotin_lipoyl	Domain	99	170	1.2e-17	64.2	Biotin-requiring enzyme
`XP_057772113.1`	Pfam	`PF02817`	E3_binding	Family	213	248	6.7e-14	52.5	e3 binding domain
`XP_057772113.1`	Pfam	`PF00198`	2-oxoacid_dh	Domain	291	520	7.9e-78	261.8	2-oxoacid dehydrogenases acyltransferase (catalytic domain)

cDNA / CDS / Protein 序列

下载基因组 DNA（仅基因区域）

每个公开基因均提供参考注释对应的转录本序列；蛋白编码基因另提供 CDS 和蛋白序列。非编码 RNA 不适用 CDS 或蛋白下载。真实 accession 的版本后缀予以保留。

cDNA

1 records

下载 cDNA FASTA

XM_057916130.1
TTTTGAGAGCAACTTTTATTTTGAGATGTGATTTCATGTATTATCAAAAAAAAATTCTTTTTTTTGTACAATCAGAAATCAAATTGACGGACGGAACTAAATTGCTCGTTAAATTCGCCACCTGTAAACTCGACCGGTTGAATTAAAACAAAAACAAAGAGAGAGAGAGAGAGAAAGAGAAGAAAACTTATGGAATTGTATAATTAATCAGTTGCAAAATTGTTTGCAAACTTTCCAAAAATTCATCAAGCAAATCAGAC...

CDS

1 records

下载 CDS FASTA

LOC130991750
ATGATTTCTCGAAAATTTTATCAGAAAAACCCGCGGAGTTTCAGCCAGTTGTGGCGTTTTGTTTCCTCCGCCGCCTCTCCGCCGTCGAAGGCCTCCAGCGCCGCCGCTCGAAGAGCTAATTCGGAGCAGGGTTCTGTCTCCCGAGCTCAAGATGACATATTTTTGAAGCCCAGAACGTTGTTTTCCTCGAAGAATCGTTGCCAAGAAAGCTCTTGGAGCATTCTGATTGGGGGTAGAAGGTGTAGATTTACAACTCAATC...

Protein

1 records

下载 Protein FASTA

XP_057772113.1
MISRKFYQKNPRSFSQLWRFVSSAASPPSKASSAAARRANSEQGSVSRAQDDIFLKPRTLFSSKNRCQESSWSILIGGRRCRFTTQSMADVPFNGEVDVPLAQTGEGIAECELLQWFVQEGDQIEEFQPLCEVQSDKATIEITSRYKGRVSKVLHVPGNIVKVGETLLKMVVDEDTFFNQPSEISEVIKAQVSDTSKLEDVDSGLSKPKIGGVRSTPAVRNLAKQYGVNIENVRGTGEDGRVLKEDILNYAARGGVMKET...

上下游序列下载

upstream/downstream 最大各 10000 bp。负链基因会自动反向互补，使最终 FASTA 为转录方向 5′→3′。

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