Gene Card 基因详情

支持统一新 ID、NCBI Gene ID、GeneID、locus_tag、Transcript ID、Protein ID，以及已人工核对的文献基因名查询。页面会先解析到丹参统一基因，再整合坐标、序列、注释、亚细胞定位、EMS 突变和下载入口。

当前解析结果

`SmilChr07G000826`

染色体: Chr07 坐标: 5830719-5836791 链方向: + 类型: protein_coding

基本信息

统一新 Gene ID	`SmilChr07G000826`
名称	SmilChr07G000826
描述	neutral ceramidase 2-like
染色体 / SeqID	Chr07 / NC_080393.1
坐标与链方向	5830719 - 5836791 / `+`

ID 对照

NCBI Gene ID	`LOC130991995`
GeneID	`130991995`
locus_tag	`-`
NCBI Name	`LOC130991995`
原始查询	`SmilChr07G000826`

查看完整 ID 对照表

功能注释

来源	GFF basic annotation; NCBI GO GAF; KEGG smil; Pfam-A/HMMER; Arabidopsis/Rice homolog
描述	neutral ceramidase 2-like
产物	neutral ceramidase 2-like
Arabidopsis	`AT1G07380` (AT1G07380) Neutral/alkaline non-lysosomal ceramidase [Source:NCBI gene (formerly Entrezgene);Acc:837250] identity=73.3; qcov=0.999; evalue=0; confidence=high
Rice	`Os01g0624000` - identity=71.6; qcov=0.982; evalue=0; confidence=high
GO	GO:0005576 (extracellular region); GO:0017040 (N-acylsphingosine amidohydrolase activity); GO:0042759 (long-chain fatty acid biosynthetic process); GO:0046512 (sphingosine biosynthetic process); GO:0046514 (ceramide catabolic process)
KEGG	smil00600 (Sphingolipid metabolism - Salvia miltiorrhiza (redroot sage)); smil01100 (Metabolic pathways - Salvia miltiorrhiza (redroot sage))
Pfam	PF04734 (Ceramidase_alk); PF17048 (Ceramidse_alk_C)
InterPro	-
eggNOG	-
NR	GeneID:130991995

打开注释模块

亚细胞定位 Top 5

Rank	定位位置	中文	Score	Protein ID
1	Lysosome	溶酶体	0.40000	`XP_057772425.1`
2	Vacuole	液泡	0.40000	`XP_057772425.1`
3	Endoplasmic reticulum	内质网	0.20000	`XP_057772425.1`
4	Nucleus	细胞核	0.00000	`XP_057772425.1`
5	Chromosome	染色体	0.00000	`XP_057772425.1`

进入亚细胞定位查询

EMS 诱变突变

下表显示该基因在丹参 EMS 材料中的前 12 个候选突变；完整结果可进入 EMS 突变库继续筛选或下载。

位置	REF	ALT	类型	影响	携带材料数	材料
`Chr7:5832196`	`C`	`T`	EMS_canonical_SNV	CDS_variant	1	B104
`Chr7:5832942`	`C`	`T`	EMS_canonical_SNV	CDS_variant	1	B82
`Chr7:5832943`	`G`	`A`	EMS_canonical_SNV	CDS_variant	3	B123,B75,C26
`Chr7:5834050`	`GGT`	`G`	2bp_deletion	frameshift_variant	2	A9,C48
`Chr7:5834050`	`GGT`	`G`	2bp_deletion	CDS_variant	2	A9,C48
`Chr7:5834127`	`C`	`T`	EMS_canonical_SNV	stop_gained	53	A1,A14,A20,A21,A24,A3,B105,B106,B108,B118,B12,B127,B138,B17,B21,B25,B27,B35,B39,B4,B45,B47,B55,B56,B62,B68,B7,B71,B73,B94,B96,C23,C24,C25,C33,C40,C46,C47,C48,C49,C5,C56,C58,C60,C66,C67,C7,C73,C75,C76,C78,C86,D3
`Chr7:5834237`	`C`	`T`	EMS_canonical_SNV	CDS_variant	3	B3,C15,D6
`Chr7:5834422`	`C`	`T`	EMS_canonical_SNV	CDS_variant	1	B133
`Chr7:5834504`	`C`	`T`	EMS_canonical_SNV	CDS_variant	3	B3,C15,D6
`Chr7:5835504`	`C`	`T`	EMS_canonical_SNV	CDS_variant	2	B111,C48
`Chr7:5835559`	`G`	`A`	EMS_canonical_SNV	CDS_variant	3	B41,C10,C42
`Chr7:5836160`	`C`	`T`	EMS_canonical_SNV	CDS_variant	1	D7

进入 EMS 突变库

预测功能结构域

结构域结果来自 Pfam-A HMM 数据库和 HMMER hmmscan；位置为对应蛋白序列上的氨基酸坐标。

XP_057772425.1

765 aa

382

765

Ceramidase_alk

Ceramidse_alk_C

PF04734 Ceramidase_alk 27-599 aa PF17048 Ceramidse_alk_C 601-764 aa

XP_057772426.1

765 aa

382

765

Ceramidase_alk

Ceramidse_alk_C

PF04734 Ceramidase_alk 27-599 aa PF17048 Ceramidse_alk_C 601-764 aa

XP_057772427.1

765 aa

382

765

Ceramidase_alk

Ceramidse_alk_C

PF04734 Ceramidase_alk 27-599 aa PF17048 Ceramidse_alk_C 601-764 aa

Protein ID	来源	结构域编号	结构域名称	类型	起始 aa	终止 aa	E-value	Score	说明
`XP_057772425.1`	Pfam	`PF04734`	Ceramidase_alk	Domain	27	599	1.8e-227	756.8	Neutral/alkaline non-lysosomal ceramidase, N-terminal
`XP_057772425.1`	Pfam	`PF17048`	Ceramidse_alk_C	Domain	601	764	7.1e-56	189.4	Neutral/alkaline non-lysosomal ceramidase, C-terminal
`XP_057772426.1`	Pfam	`PF04734`	Ceramidase_alk	Domain	27	599	1.8e-227	756.8	Neutral/alkaline non-lysosomal ceramidase, N-terminal
`XP_057772426.1`	Pfam	`PF17048`	Ceramidse_alk_C	Domain	601	764	7.1e-56	189.4	Neutral/alkaline non-lysosomal ceramidase, C-terminal
`XP_057772427.1`	Pfam	`PF04734`	Ceramidase_alk	Domain	27	599	1.8e-227	756.8	Neutral/alkaline non-lysosomal ceramidase, N-terminal
`XP_057772427.1`	Pfam	`PF17048`	Ceramidse_alk_C	Domain	601	764	7.1e-56	189.4	Neutral/alkaline non-lysosomal ceramidase, C-terminal

cDNA / CDS / Protein 序列

下载基因组 DNA（仅基因区域）

每个公开基因均提供参考注释对应的转录本序列；蛋白编码基因另提供 CDS 和蛋白序列。非编码 RNA 不适用 CDS 或蛋白下载。真实 accession 的版本后缀予以保留。

cDNA

3 records

下载 cDNA FASTA

XM_057916444.1
GTGAACAATGTGATAATGTCGATGTTACATTAAAAACAATGTAACATAAAATCTTTGCACCACGTCATAAATTCACCGAGCTAAACTGCCGCCGTGCCCCACCTCCAACCACCGCGCGCTACCGCCGCTCCACGGCTGAAGCAAAATGAAAAAGGAACGAGCACTACTGTAGCAGCAGCAGATTATATATAAGCACGTGGAGACTACTCAACCGAACCTAGCAACCCACTCACAAACTTCACTTCCACGCCAAGCCACCA...

XM_057916443.1
CAATGTAACATAAAATCTTTGCACCACGTCATAAATTCACCGAGCTAAACTGCCGCCGTGCCCCACCTCCAACCACCGCGCGCTACCGCCGCTCCACGGCTGAAGCAAAATGAAAAAGGAACGAGCACTACTGTAGCAGCAGCAGATTATATATAAGCACGTGGAGACTACTCAACCGAACCTAGCAACCCACTCACAAACTTCACTTCCACGCCAAGCCACCATTCTTTTTTCTCCCTTGCCCATTTTGTTCAGTTTCA...

CDS

3 records

下载 CDS FASTA

LOC130991995
ATGGGGAGATCAATTAGTATGATTTGGTTACCGATATTGTTATTGCTCTTTTTGGAGAGTGGGAGGGCTTCCAACCACCTAATTGGGCTCGGAAGCTATGACATCACCGGGCCGGCTGCTGATGTCAACATGATGGGATATGCAAACATGGAGCAGGTGGCATCAGGTGTTCACTTCAGGTTGCGAGCTCGGGCCTTCATTGTTGCACAGCCACAAGGGAAACGAGTCCTGTTTGTGAATCTAGATGCTTGTATGGCATC...

Protein

3 records

下载 Protein FASTA

XP_057772425.1
MGRSISMIWLPILLLLFLESGRASNHLIGLGSYDITGPAADVNMMGYANMEQVASGVHFRLRARAFIVAQPQGKRVLFVNLDACMASQLVTIKVLERLKARYGDLYTEKNVAISGIHTHSGPGGYLQYIVYIVTSLGFVRQSFDALVDGIEQTIIQAHDNIRPGSVYVNKGELLDAGINRSPSAYLNNPAAERSKYKYDVDKEMTLLKFADDEWGPVGSFNWFATHGTSMGRTNSLISGDNKGTAARIMEDWFDQNNGRS...

XP_057772426.1
MGRSISMIWLPILLLLFLESGRASNHLIGLGSYDITGPAADVNMMGYANMEQVASGVHFRLRARAFIVAQPQGKRVLFVNLDACMASQLVTIKVLERLKARYGDLYTEKNVAISGIHTHSGPGGYLQYIVYIVTSLGFVRQSFDALVDGIEQTIIQAHDNIRPGSVYVNKGELLDAGINRSPSAYLNNPAAERSKYKYDVDKEMTLLKFADDEWGPVGSFNWFATHGTSMGRTNSLISGDNKGTAARIMEDWFDQNNGRS...

上下游序列下载

upstream/downstream 最大各 10000 bp。负链基因会自动反向互补，使最终 FASTA 为转录方向 5′→3′。

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