Gene Card 基因详情

支持统一新 ID、NCBI Gene ID、GeneID、locus_tag、Transcript ID、Protein ID，以及已人工核对的文献基因名查询。页面会先解析到丹参统一基因，再整合坐标、序列、注释、亚细胞定位、EMS 突变和下载入口。

当前解析结果

`SmilChr07G001001`

染色体: Chr07 坐标: 7277785-7281231 链方向: + 类型: protein_coding

基本信息

统一新 Gene ID	`SmilChr07G001001`
名称	SmilChr07G001001
描述	histidine biosynthesis bifunctional protein hisIE, chloroplastic
染色体 / SeqID	Chr07 / NC_080393.1
坐标与链方向	7277785 - 7281231 / `+`

ID 对照

NCBI Gene ID	`LOC130992162`
GeneID	`130992162`
locus_tag	`-`
NCBI Name	`LOC130992162`
原始查询	`SmilChr07G001001`

查看完整 ID 对照表

功能注释

来源	GFF basic annotation; NCBI GO GAF; KEGG smil; Pfam-A/HMMER; Arabidopsis/Rice homolog
描述	histidine biosynthesis bifunctional protein hisIE, chloroplastic
产物	histidine biosynthesis bifunctional protein hisIE%2C chloroplastic
Arabidopsis	`AT1G31860` (AT-IE) histidine biosynthesis bifunctional protein (HISIE) [Source:NCBI gene (formerly Entrezgene);Acc:840076] identity=74.4; qcov=0.99; evalue=5.16e-110; confidence=high
Rice	`Os01g0276500` - identity=70.3; qcov=0.99; evalue=5.37e-103; confidence=high
GO	GO:0000105 (L-histidine biosynthetic process); GO:0004635 (phosphoribosyl-AMP cyclohydrolase activity); GO:0004636 (phosphoribosyl-ATP diphosphatase activity)
KEGG	smil00340 (Histidine metabolism - Salvia miltiorrhiza (redroot sage)); smil01100 (Metabolic pathways - Salvia miltiorrhiza (redroot sage)); smil01110 (Biosynthesis of secondary metabolites - Salvia miltiorrhiza (redroot sage)); smil01230 (Biosynthesis of amino acids - Salvia miltiorrhiza (redroot sage))
Pfam	PF01502 (PRA-CH); PF01503 (PRA-PH); PF03819 (MazG)
InterPro	-
eggNOG	-
NR	GeneID:130992162

打开注释模块

亚细胞定位 Top 5

Rank	定位位置	中文	Score	Protein ID
1	Chloroplast	叶绿体	1.00000	`XP_057772675.1`
2	Cytoplasm	细胞质	1.00000	`XP_057772677.1`
3	Chloroplast stroma	叶绿体基质	1.00000	`XP_057772675.1`
4	Cytosol	细胞质基质	1.00000	`XP_057772677.1`
5	Nucleus	细胞核	0.00000	`XP_057772675.1`

进入亚细胞定位查询

EMS 诱变突变

下表显示该基因在丹参 EMS 材料中的前 12 个候选突变；完整结果可进入 EMS 突变库继续筛选或下载。

位置	REF	ALT	类型	影响	携带材料数	材料
`Chr7:7278652`	`G`	`A`	EMS_canonical_SNV	CDS_variant	1	C26
`Chr7:7280283`	`G`	`A`	EMS_canonical_SNV	CDS_variant	1	C72
`Chr7:7280616`	`G`	`A`	EMS_canonical_SNV	CDS_variant	5	B14,B41,C10,C42,C71
`Chr7:7280840`	`G`	`A`	EMS_canonical_SNV	CDS_variant	5	B14,B41,C10,C42,C71
`Chr7:7280900`	`C`	`T`	EMS_canonical_SNV	CDS_variant	3	B107,B76,C27
`Chr7:7280906`	`C`	`T`	EMS_canonical_SNV	CDS_variant	5	B123,B128,B136,B32,D11
`Chr7:7280991`	`G`	`A`	EMS_canonical_SNV	CDS_variant	1	B128

进入 EMS 突变库

预测功能结构域

结构域结果来自 Pfam-A HMM 数据库和 HMMER hmmscan；位置为对应蛋白序列上的氨基酸坐标。

XP_057772675.1

283 aa

142

283

PRA-CH

PRA-PH

MazG

PF01502 PRA-CH 83-156 aa PF01503 PRA-PH 180-267 aa PF03819 MazG 212-264 aa

XP_057772676.1

280 aa

140

280

PRA-CH

PRA-PH

MazG

PF01502 PRA-CH 80-153 aa PF01503 PRA-PH 177-264 aa PF03819 MazG 209-261 aa

XP_057772677.1

201 aa

100

201

PRA-CH

PRA-PH

MazG

PF01502 PRA-CH 1-74 aa PF01503 PRA-PH 98-185 aa PF03819 MazG 130-182 aa

XP_057772678.1

201 aa

100

201

PRA-CH

PRA-PH

MazG

PF01502 PRA-CH 1-74 aa PF01503 PRA-PH 98-185 aa PF03819 MazG 130-182 aa

XP_057772680.1

201 aa

100

201

PRA-CH

PRA-PH

MazG

PF01502 PRA-CH 1-74 aa PF01503 PRA-PH 98-185 aa PF03819 MazG 130-182 aa

Protein ID	来源	结构域编号	结构域名称	类型	起始 aa	终止 aa	E-value	Score	说明
`XP_057772675.1`	Pfam	`PF01502`	PRA-CH	Family	83	156	1.5e-27	95.8	Phosphoribosyl-AMP cyclohydrolase
`XP_057772675.1`	Pfam	`PF01503`	PRA-PH	Family	180	267	7e-15	55.9	Phosphoribosyl-ATP pyrophosphohydrolase
`XP_057772675.1`	Pfam	`PF03819`	MazG	Domain	212	264	3.7e-05	24.6	MazG nucleotide pyrophosphohydrolase domain
`XP_057772676.1`	Pfam	`PF01502`	PRA-CH	Family	80	153	1.5e-27	95.9	Phosphoribosyl-AMP cyclohydrolase
`XP_057772676.1`	Pfam	`PF01503`	PRA-PH	Family	177	264	6.9e-15	55.9	Phosphoribosyl-ATP pyrophosphohydrolase
`XP_057772676.1`	Pfam	`PF03819`	MazG	Domain	209	261	3.7e-05	24.6	MazG nucleotide pyrophosphohydrolase domain
`XP_057772677.1`	Pfam	`PF01502`	PRA-CH	Family	1	74	8.7e-28	96.6	Phosphoribosyl-AMP cyclohydrolase
`XP_057772677.1`	Pfam	`PF01503`	PRA-PH	Family	98	185	3.5e-15	56.9	Phosphoribosyl-ATP pyrophosphohydrolase
`XP_057772677.1`	Pfam	`PF03819`	MazG	Domain	130	182	2e-05	25.5	MazG nucleotide pyrophosphohydrolase domain
`XP_057772678.1`	Pfam	`PF01502`	PRA-CH	Family	1	74	8.7e-28	96.6	Phosphoribosyl-AMP cyclohydrolase
`XP_057772678.1`	Pfam	`PF01503`	PRA-PH	Family	98	185	3.5e-15	56.9	Phosphoribosyl-ATP pyrophosphohydrolase
`XP_057772678.1`	Pfam	`PF03819`	MazG	Domain	130	182	2e-05	25.5	MazG nucleotide pyrophosphohydrolase domain
`XP_057772680.1`	Pfam	`PF01502`	PRA-CH	Family	1	74	8.7e-28	96.6	Phosphoribosyl-AMP cyclohydrolase
`XP_057772680.1`	Pfam	`PF01503`	PRA-PH	Family	98	185	3.5e-15	56.9	Phosphoribosyl-ATP pyrophosphohydrolase
`XP_057772680.1`	Pfam	`PF03819`	MazG	Domain	130	182	2e-05	25.5	MazG nucleotide pyrophosphohydrolase domain

cDNA / CDS / Protein 序列

下载基因组 DNA（仅基因区域）

每个公开基因均提供参考注释对应的转录本序列；蛋白编码基因另提供 CDS 和蛋白序列。非编码 RNA 不适用 CDS 或蛋白下载。真实 accession 的版本后缀予以保留。

cDNA

5 records

下载 cDNA FASTA

XM_057916692.1
GAGTTGGTAGGATTTCATCATTCTGATGCAAAATTGCACAGGACAGGAGATTCCCTTATACCTCAGTTATTATTTTTTGTTTATATGTTTTTTAATTTATTTTTAACAATCGCAATTCGTAACCCTAATTTTTGTTTGACCTTTGACCATTGAAGCCAACGATCTGCCATTTTCCAACCCTAATTTTTCTCTATAAATACACACCACACACACTCACGCAGACAGCATCAGCGTCACTGCACTCTCTGCTCGTTCACAAT...

XM_057916693.1
TTTCATCATTCTGATGCAAAATTGCACAGGACAGGAGATTCCCTTATACCTCAGTTATTATTTTTTGTTTATATGTTTTTTAATTTATTTTTAACAATCGCAATTCGTAACCCTAATTTTTGTTTGACCTTTGACCATTGAAGCCAACGATCTGCCATTTTCCAACCCTAATTTTTCTCTATAAATACACACCACACACACTCACGCAGACAGCATCAGCGTCACTGCACTCTCTGCTCGTTCACAATAACCTCAATTTG...

CDS

5 records

下载 CDS FASTA

LOC130992162
ATGGCTGTTCCATACACCAATTGCTTTCAACTCCCAAAAGTAAACCCAAAATGTCACATTTTTAGCTCGTCTGGTGGGCTCTCCACCGGGGTCTCTCCCGCACATTGTTGCCTTAAAACTTCCCCCCCGGTTATGCATTTAGAAGCCAAAGTAAGTCAGGTTGATCCCTTGTTGGATAGTGTCAAGTGGGACGACAGAGGTTTGGCAGTGGCAATAGCTCAGAATGTGGATACCGGAGCGGTTTTAATGCAAGGGTTTGT...

LOC130992162
ATGGCTGTTCCATACACCAATTGCTTTCAACTCCCAAAAGTAAACCCAAAATGTCACATTTTTAGCTCGTCTGGTGGGCTCTCCACCGGGGTCTCTCCCGCACATTGTTGCCTTAAAACTTCCCCCCCGGTTATGCATTTAGAAGCCAAAGTTGATCCCTTGTTGGATAGTGTCAAGTGGGACGACAGAGGTTTGGCAGTGGCAATAGCTCAGAATGTGGATACCGGAGCGGTTTTAATGCAAGGGTTTGTCAACAAAGA...

Protein

5 records

下载 Protein FASTA

XP_057772675.1
MAVPYTNCFQLPKVNPKCHIFSSSGGLSTGVSPAHCCLKTSPPVMHLEAKVSQVDPLLDSVKWDDRGLAVAIAQNVDTGAVLMQGFVNKEALLKTITSKQATFYSRSRSTLWTKGETSMNFINVSDVFLDCDRDSIIYLGKPDGPTCHTGAETCYYTSVDDIINDSPVDGSKLALTTLYALESTISKRKEELSENPDSKPSWTKRLLLDEKLLCSKIREEADELCRTLEENEDQTRTASEMADVLYHAMVLLALKGVKVE...

XP_057772676.1
MAVPYTNCFQLPKVNPKCHIFSSSGGLSTGVSPAHCCLKTSPPVMHLEAKVDPLLDSVKWDDRGLAVAIAQNVDTGAVLMQGFVNKEALLKTITSKQATFYSRSRSTLWTKGETSMNFINVSDVFLDCDRDSIIYLGKPDGPTCHTGAETCYYTSVDDIINDSPVDGSKLALTTLYALESTISKRKEELSENPDSKPSWTKRLLLDEKLLCSKIREEADELCRTLEENEDQTRTASEMADVLYHAMVLLALKGVKVEDVL...

上下游序列下载

upstream/downstream 最大各 10000 bp。负链基因会自动反向互补，使最终 FASTA 为转录方向 5′→3′。

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