Gene Card 基因详情

支持统一新 ID、NCBI Gene ID、GeneID、locus_tag、Transcript ID、Protein ID，以及已人工核对的文献基因名查询。页面会先解析到丹参统一基因，再整合坐标、序列、注释、亚细胞定位、EMS 突变和下载入口。

当前解析结果

`SmilChr07G001448`

染色体: Chr07 坐标: 11256335-11259836 链方向: + 类型: protein_coding

基本信息

统一新 Gene ID	`SmilChr07G001448`
名称	SmilChr07G001448
描述	2-oxoisovalerate dehydrogenase subunit beta 1, mitochondrial
染色体 / SeqID	Chr07 / NC_080393.1
坐标与链方向	11256335 - 11259836 / `+`

ID 对照

NCBI Gene ID	`LOC130992633`
GeneID	`130992633`
locus_tag	`-`
NCBI Name	`LOC130992633`
原始查询	`SmilChr07G001448`

查看完整 ID 对照表

功能注释

来源	GFF basic annotation; NCBI GO GAF; KEGG smil; Pfam-A/HMMER; Arabidopsis/Rice homolog
描述	2-oxoisovalerate dehydrogenase subunit beta 1, mitochondrial
产物	2-oxoisovalerate dehydrogenase subunit beta 1%2C mitochondrial
Arabidopsis	`AT1G55510` (BCDH BETA1) branched-chain alpha-keto acid decarboxylase E1 beta subunit [Source:NCBI gene (formerly Entrezgene);Acc:841998] identity=86.8; qcov=0.978; evalue=0; confidence=high
Rice	`Os07g0170100` - identity=87.8; qcov=0.919; evalue=0; confidence=high
GO	GO:0003824 (catalytic activity); GO:0005947 (GO:0005947); GO:0007584 (response to nutrient); GO:0009083 (branched-chain amino acid catabolic process)
KEGG	smil00280 (Valine, leucine and isoleucine degradation - Salvia miltiorrhiza (redroot sage)); smil00640 (Propanoate metabolism - Salvia miltiorrhiza (redroot sage)); smil00785 (Lipoic acid metabolism - Salvia miltiorrhiza (redroot sage)); smil01100 (Metabolic pathways - Salvia miltiorrhiza (redroot sage)); smil01110 (Biosynthesis of secondary metabolites - Salvia miltiorrhiza (redroot sage)); smil01210 (2-Oxocarboxylic acid metabolism - Salvia miltiorrhiza (redroot sage))
Pfam	PF02779 (Transket_pyr); PF02780 (Transketolase_C)
InterPro	-
eggNOG	-
NR	GeneID:130992633

打开注释模块

亚细胞定位 Top 5

Rank	定位位置	中文	Score	Protein ID
1	Mitochondrion	线粒体	1.00000	`XP_057773332.1`
2	Mitochondrion matrix	线粒体基质	1.00000	`XP_057773332.1`
3	Mitochondrion inner membrane	线粒体内膜	0.60000	`XP_057773334.1`
4	Mitochondrion membrane	线粒体膜	0.20000	`XP_057773334.1`
5	Nucleus	细胞核	0.00000	`XP_057773332.1`

进入亚细胞定位查询

EMS 诱变突变

下表显示该基因在丹参 EMS 材料中的前 12 个候选突变；完整结果可进入 EMS 突变库继续筛选或下载。

位置	REF	ALT	类型	影响	携带材料数	材料
`Chr7:11256643`	`C`	`T`	EMS_canonical_SNV	CDS_variant	1	B44
`Chr7:11257278`	`C`	`T`	EMS_canonical_SNV	CDS_variant	2	C3,D1
`Chr7:11259275`	`C`	`T`	EMS_canonical_SNV	CDS_variant	2	C2,C39
`Chr7:11259455`	`C`	`T`	EMS_canonical_SNV	CDS_variant	1	B44
`Chr7:11259502`	`C`	`CT`	1bp_insertion	stop_gained,frameshift_variant	37	A11,A14,B104,B105,B113,B115,B117,B12,B120,B121,B137,B25,B3,B44,B49,B52,B75,B77,B79,B88,B89,B9,B94,B98,C16,C27,C30,C33,C36,C4,C55,C57,C59,C63,C8,D11,D8
`Chr7:11259518`	`C`	`T`	EMS_canonical_SNV	stop_gained	5	B130,B84,C41,C62,C74
`Chr7:11259518`	`C`	`T`	EMS_canonical_SNV	CDS_variant	5	B130,B84,C41,C62,C74
`Chr7:11259519`	`G`	`GAT`	2bp_insertion	frameshift_variant	46	A15,A21,A5,A6,A8,B101,B124,B133,B134,B137,B16,B17,B18,B19,B21,B23,B27,B28,B66,B67,B76,B79,B87,B91,B95,B97,C1,C13,C16,C19,C20,C28,C29,C31,C33,C46,C48,C5,C50,C53,C54,C57,C76,C78,D2,D8

进入 EMS 突变库

预测功能结构域

结构域结果来自 Pfam-A HMM 数据库和 HMMER hmmscan；位置为对应蛋白序列上的氨基酸坐标。

XP_057773332.1

361 aa

180

361

Transket_pyr

Transketolase_C

PF02779 Transket_pyr 36-211 aa PF02780 Transketolase_C 228-347 aa

XP_057773334.1

357 aa

178

357

Transket_pyr

Transketolase_C

PF02779 Transket_pyr 36-211 aa PF02780 Transketolase_C 228-347 aa

Protein ID	来源	结构域编号	结构域名称	类型	起始 aa	终止 aa	E-value	Score	说明
`XP_057773332.1`	Pfam	`PF02779`	Transket_pyr	Domain	36	211	6.7e-39	134.0	Transketolase, pyrimidine binding domain
`XP_057773332.1`	Pfam	`PF02780`	Transketolase_C	Domain	228	347	4.5e-35	121.0	Transketolase, C-terminal domain
`XP_057773334.1`	Pfam	`PF02779`	Transket_pyr	Domain	36	211	6.6e-39	134.1	Transketolase, pyrimidine binding domain
`XP_057773334.1`	Pfam	`PF02780`	Transketolase_C	Domain	228	347	2.9e-35	121.6	Transketolase, C-terminal domain

cDNA / CDS / Protein 序列

下载基因组 DNA（仅基因区域）

每个公开基因均提供参考注释对应的转录本序列；蛋白编码基因另提供 CDS 和蛋白序列。非编码 RNA 不适用 CDS 或蛋白下载。真实 accession 的版本后缀予以保留。

cDNA

2 records

下载 cDNA FASTA

XM_057917351.1
AGGGAAGTCCGATCTCATCTCACGGCTCTATTAATTAGTTTTCTGTCCACATTAATTAATAGTGTTGGTTTAGAAAGTCCGTTTGGCAGACACGGAGATATGGATTAGATCCATTTCTACACTGTGGCTCTGTGGGGTTATCTACTTAATTAAATTAAACACCAATTTTCTCCAAAAAAGATGATGTTAGTAAGGATAGCTTTAACCAACCTACCAACCTCACTCATTTATGATTTATTCATGAATCCCATCTCCCTCCC...

XM_057917349.1
TGTTGGTTTAGAAAGTCCGTTTGGCAGACACGGAGATATGGATTAGATCCATTTCTACACTGTGGCTCTGTGGGGTTATCTACTTAATTAAATTAAACACCAATTTTCTCCAAAAAAGATGATGTTAGTAAGGATAGCTTTAACCAACCTACCAACCTCACTCATTTATGATTTATTCATGAATCCCATCTCCCTCCCTACCCAAGGAAACAACACTTTGATTTCATTTGGAACCGCATAAGATGGCTTGCACCGCCGCC...

CDS

2 records

下载 CDS FASTA

LOC130992633
ATGGCTTGCACCGCCGCCCGCAGCCTCGGAAAATTCTGTGGGATTTGGTCTTCGGCTTCGAGGGGTCTGGGGACGGCCGCCGTCGACGGCGAAGGCGGCACCAAGAGCATCAATTTGTTCTCCGCCATAAACCAGGCCCTTCATATAGCCCTGGATACCGACCCTCGTGCTTATGTATTCGGGGAAGATGTGGGATTTGGTGGTGTTTTCCGCTGCACTACTGGTCTAGCTGATCAATTTGGCAAACGTCGAGTTTTCAA...

Protein

2 records

下载 Protein FASTA

XP_057773332.1
MACTAARSLGKFCGIWSSASRGLGTAAVDGEGGTKSINLFSAINQALHIALDTDPRAYVFGEDVGFGGVFRCTTGLADQFGKRRVFNTPLCEQGIVGFAIGLAAMGNRAIAEIQFADYIFPAFDQIVNEAAKFRYRSGNQFNCGGLTIRAPYGAVGHGGHYHSQSPEAFFCHVPGIKVVIPRSPLQAKGLLLSSIRDPNPVVFFEPKWLYRLAVEEVPEQDYMLPLSEAEVIREGSDITLVGWGAQLSIMEQACMDAEKE...

XP_057773334.1
MACTAARSLGKFCGIWSSASRGLGTAAVDGEGGTKSINLFSAINQALHIALDTDPRAYVFGEDVGFGGVFRCTTGLADQFGKRRVFNTPLCEQGIVGFAIGLAAMGNRAIAEIQFADYIFPAFDQIVNEAAKFRYRSGNQFNCGGLTIRAPYGAVGHGGHYHSQSPEAFFCHVPGIKVVIPRSPLQAKGLLLSSIRDPNPVVFFEPKWLYRLAVEEVPEQDYMLPLSEAEVIREGSDITLVGWGAQLSIMEQACMDAEKE...

上下游序列下载

upstream/downstream 最大各 10000 bp。负链基因会自动反向互补，使最终 FASTA 为转录方向 5′→3′。

下载 upstream 下载 downstream 下载 upstream + gene + downstream

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