Gene Card 基因详情

支持统一新 ID、NCBI Gene ID、GeneID、locus_tag、Transcript ID、Protein ID，以及已人工核对的文献基因名查询。页面会先解析到丹参统一基因，再整合坐标、序列、注释、亚细胞定位、EMS 突变和下载入口。

当前解析结果

`SmilChr07G002393`

染色体: Chr07 坐标: 22304991-22315170 链方向: + 类型: protein_coding

基本信息

统一新 Gene ID	`SmilChr07G002393`
名称	SmilChr07G002393
描述	cleavage and polyadenylation specificity factor subunit 2
染色体 / SeqID	Chr07 / NC_080393.1
坐标与链方向	22304991 - 22315170 / `+`

ID 对照

NCBI Gene ID	`LOC130993477`
GeneID	`130993477`
locus_tag	`-`
NCBI Name	`LOC130993477`
原始查询	`SmilChr07G002393`

查看完整 ID 对照表

功能注释

来源	GFF basic annotation; NCBI GO GAF; KEGG smil; Pfam-A/HMMER; Arabidopsis/Rice homolog
描述	cleavage and polyadenylation specificity factor subunit 2
产物	cleavage and polyadenylation specificity factor subunit 2
Arabidopsis	`AT5G23880` (CPSF100) cleavage and polyadenylation specificity factor 100 [Source:NCBI gene (formerly Entrezgene);Acc:832453] identity=70.3; qcov=1.01; evalue=0; confidence=high
Rice	`Os09g0569400` - identity=70.1; qcov=1; evalue=0; confidence=high
GO	GO:0003723 (RNA binding); GO:0005847 (mRNA cleavage and polyadenylation specificity factor complex); GO:0006378 (GO:0006378); GO:0006398 (mRNA 3'-end processing by stem-loop binding and cleavage)
KEGG	smil03015 (mRNA surveillance pathway - Salvia miltiorrhiza (redroot sage))
Pfam	PF00753 (Lactamase_B); PF07521 (RMMBL); PF10996 (Beta-Casp); PF13299 (CPSF100_C); PF16661 (Lactamase_B_6)
InterPro	-
eggNOG	-
NR	GeneID:130993477

打开注释模块

亚细胞定位 Top 5

Rank	定位位置	中文	Score	Protein ID
1	Nucleus	细胞核	1.00000	`XP_057774360.1`
2	Cytoplasm	细胞质	0.60000	`XP_057774360.1`
3	Cytosol	细胞质基质	0.40000	`XP_057774357.1`
4	Nucleoplasm	核质	0.20000	`XP_057774360.1`
5	Chromosome	染色体	0.00000	`XP_057774357.1`

进入亚细胞定位查询

EMS 诱变突变

下表显示该基因在丹参 EMS 材料中的前 12 个候选突变；完整结果可进入 EMS 突变库继续筛选或下载。

位置	REF	ALT	类型	影响	携带材料数	材料
`Chr7:22307387`	`A`	`AT`	1bp_insertion	frameshift_variant	8	B100,B112,B135,B25,B38,B62,C8,D7
`Chr7:22307392`	`G`	`A`	EMS_canonical_SNV	CDS_variant	3	B135,B25,D7
`Chr7:22307418`	`G`	`A`	EMS_canonical_SNV	CDS_variant	4	A11,B25,B64,B69
`Chr7:22307423`	`C`	`T`	EMS_canonical_SNV	CDS_variant	3	A11,B25,B64
`Chr7:22307433`	`TTA`	`T`	2bp_deletion	frameshift_variant	1	A11
`Chr7:22307433`	`TTA`	`T`	2bp_deletion	CDS_variant	1	A11
`Chr7:22307972`	`TG`	`T`	1bp_deletion	frameshift_variant	15	A11,A15,A21,B2,B28,B40,B64,B99,C11,C27,C54,C69,C75,D4,D9
`Chr7:22307974`	`CA`	`C`	1bp_deletion	frameshift_variant	15	A11,A15,A21,B2,B28,B40,B64,B99,C11,C27,C54,C69,C75,D4,D9
`Chr7:22307979`	`CTT`	`C`	2bp_deletion	frameshift_variant	15	A11,A15,A21,B2,B28,B40,B64,B99,C11,C27,C54,C69,C75,D4,D9
`Chr7:22308186`	`TTA`	`T`	2bp_deletion	frameshift_variant	6	B112,B39,B62,C6,C79,C8
`Chr7:22308210`	`G`	`A`	EMS_canonical_SNV	CDS_variant	1	C51
`Chr7:22308772`	`C`	`CG`	1bp_insertion	frameshift_variant	2	A15,C54

进入 EMS 突变库

预测功能结构域

结构域结果来自 Pfam-A HMM 数据库和 HMMER hmmscan；位置为对应蛋白序列上的氨基酸坐标。

XP_057774357.1

739 aa

370

739

Lactamase_B

Lactamase_B_6

Beta-Casp

RMMBL

CPSF100_C

PF00753 Lactamase_B 19-97 aa PF16661 Lactamase_B_6 22-198 aa PF10996 Beta-Casp 243-365 aa PF07521 RMMBL 536-586 aa PF13299 CPSF100_C 645-736 aa

XP_057774358.1

739 aa

370

739

Lactamase_B

Lactamase_B_6

Beta-Casp

RMMBL

CPSF100_C

PF00753 Lactamase_B 19-97 aa PF16661 Lactamase_B_6 22-198 aa PF10996 Beta-Casp 243-365 aa PF07521 RMMBL 536-586 aa PF13299 CPSF100_C 645-736 aa

XP_057774359.1

739 aa

370

739

Lactamase_B

Lactamase_B_6

Beta-Casp

RMMBL

CPSF100_C

PF00753 Lactamase_B 19-97 aa PF16661 Lactamase_B_6 22-198 aa PF10996 Beta-Casp 243-365 aa PF07521 RMMBL 536-586 aa PF13299 CPSF100_C 645-736 aa

XP_057774360.1

603 aa

302

603

Lactamase_B_6

Beta-Casp

RMMBL

CPSF100_C

PF16661 Lactamase_B_6 2-62 aa PF10996 Beta-Casp 107-229 aa PF07521 RMMBL 400-450 aa PF13299 CPSF100_C 509-600 aa

Protein ID	来源	结构域编号	结构域名称	类型	起始 aa	终止 aa	E-value	Score	说明
`XP_057774357.1`	Pfam	`PF00753`	Lactamase_B	Domain	19	97	6.8e-07	30.1	Metallo-beta-lactamase superfamily
`XP_057774357.1`	Pfam	`PF16661`	Lactamase_B_6	Domain	22	198	1e-54	185.6	Metallo-beta-lactamase superfamily domain
`XP_057774357.1`	Pfam	`PF10996`	Beta-Casp	Domain	243	365	1.8e-22	80.9	Beta-Casp domain
`XP_057774357.1`	Pfam	`PF07521`	RMMBL	Motif	536	586	1.2e-09	38.7	Zn-dependent metallo-hydrolase RNA specificity domain
`XP_057774357.1`	Pfam	`PF13299`	CPSF100_C	Family	645	736	7.4e-23	82.3	Cleavage and polyadenylation factor 2 C-terminal
`XP_057774358.1`	Pfam	`PF00753`	Lactamase_B	Domain	19	97	6.8e-07	30.1	Metallo-beta-lactamase superfamily
`XP_057774358.1`	Pfam	`PF16661`	Lactamase_B_6	Domain	22	198	1e-54	185.6	Metallo-beta-lactamase superfamily domain
`XP_057774358.1`	Pfam	`PF10996`	Beta-Casp	Domain	243	365	1.8e-22	80.9	Beta-Casp domain
`XP_057774358.1`	Pfam	`PF07521`	RMMBL	Motif	536	586	1.2e-09	38.7	Zn-dependent metallo-hydrolase RNA specificity domain
`XP_057774358.1`	Pfam	`PF13299`	CPSF100_C	Family	645	736	7.4e-23	82.3	Cleavage and polyadenylation factor 2 C-terminal
`XP_057774359.1`	Pfam	`PF00753`	Lactamase_B	Domain	19	97	6.8e-07	30.1	Metallo-beta-lactamase superfamily
`XP_057774359.1`	Pfam	`PF16661`	Lactamase_B_6	Domain	22	198	1e-54	185.6	Metallo-beta-lactamase superfamily domain
`XP_057774359.1`	Pfam	`PF10996`	Beta-Casp	Domain	243	365	1.8e-22	80.9	Beta-Casp domain
`XP_057774359.1`	Pfam	`PF07521`	RMMBL	Motif	536	586	1.2e-09	38.7	Zn-dependent metallo-hydrolase RNA specificity domain
`XP_057774359.1`	Pfam	`PF13299`	CPSF100_C	Family	645	736	7.4e-23	82.3	Cleavage and polyadenylation factor 2 C-terminal
`XP_057774360.1`	Pfam	`PF16661`	Lactamase_B_6	Domain	2	62	2.4e-17	63.7	Metallo-beta-lactamase superfamily domain
`XP_057774360.1`	Pfam	`PF10996`	Beta-Casp	Domain	107	229	1.3e-22	81.3	Beta-Casp domain
`XP_057774360.1`	Pfam	`PF07521`	RMMBL	Motif	400	450	9.1e-10	39.1	Zn-dependent metallo-hydrolase RNA specificity domain
`XP_057774360.1`	Pfam	`PF13299`	CPSF100_C	Family	509	600	3.2e-23	83.5	Cleavage and polyadenylation factor 2 C-terminal

cDNA / CDS / Protein 序列

下载基因组 DNA（仅基因区域）

每个公开基因均提供参考注释对应的转录本序列；蛋白编码基因另提供 CDS 和蛋白序列。非编码 RNA 不适用 CDS 或蛋白下载。真实 accession 的版本后缀予以保留。

cDNA

4 records

下载 cDNA FASTA

XM_057918375.1
AAAATACTTAGAACGGGCAAAGAATAGTTTATTTTTAAGTTTCCAGGAAGAAGAAAGAGATACCGAAAGTTTCCAAGAAGAAAGAATGACGCTCTTCTCCAACAAGTTCACTCGTGGAAAAAAAAGCCCTAAATTACCCGTTTCTGTGGCGCTGCGTTTTCCCGCGTAAAATCCTCAAGCACCGGAGCTACGACGGTGAAGCGCCGAAAAAATCTGAGGCTGTAGAAGATAAATAACCCACATTGAAATGGGGACGTCAG...

XM_057918376.1
CTTAGAACGGGCAAAGAATAGTTTATTTTTAAGTTTCCAGGAAGAAGAAAGAGATACCGAAAGTTTCCAAGAAGAAAGAATGGTTGGAAATACTACGCTCTTCTCCAACAAGTTCACTCGTGGAAAAAAAAGCCCTAAATTACCCGTTTCTGTGGCGCTGCGTTTTCCCGCGTAAAATCCTCAAGCACCGGAGCTACGACGGTGAAGCGCCGAAAAAATCTGAGGCTGTAGAAGATAAATAACCCACATTGAAATGGGGA...

CDS

4 records

下载 CDS FASTA

LOC130993477
ATGGGGACGTCAGTGCAGGTGAAGCCGCTGTGTGGAGTGTACAACGAGAATCCGCTGTCGTACTTAGTCTCAATCGACGGTTTCAATTTCCTCGTCGACTGCGGTTGGAACGACCAGTTCGACACCTCTCTTCTAGAACCCCTATCCAGGGTTGCTTCAACTGTGGATGCTGTCTTACTATCACACTCAGACACACTTCATCTTGGTGCTTTACCTTATGCTATGAAGCAATTTGGAATTTCTGCTCCAGTGTTTGCAAC...

Protein

4 records

下载 Protein FASTA

XP_057774357.1
MGTSVQVKPLCGVYNENPLSYLVSIDGFNFLVDCGWNDQFDTSLLEPLSRVASTVDAVLLSHSDTLHLGALPYAMKQFGISAPVFATEPVYRLGLLTMYDHYLSRKQVSEFDLFTLDDIDSAFQNIIRLTYSQNYYMSGKGEGIVIAPLAAGHLLGGTFWKITKDGEDVIYAVDFNHRKEKLLNGTVLESFVRPAVLITDAYNALLSNQPPRRQKDQQLLDAILKTLRADGNILVPVDTAGRVLELLLILEQYWEHQHLT...

XP_057774358.1
MGTSVQVKPLCGVYNENPLSYLVSIDGFNFLVDCGWNDQFDTSLLEPLSRVASTVDAVLLSHSDTLHLGALPYAMKQFGISAPVFATEPVYRLGLLTMYDHYLSRKQVSEFDLFTLDDIDSAFQNIIRLTYSQNYYMSGKGEGIVIAPLAAGHLLGGTFWKITKDGEDVIYAVDFNHRKEKLLNGTVLESFVRPAVLITDAYNALLSNQPPRRQKDQQLLDAILKTLRADGNILVPVDTAGRVLELLLILEQYWEHQHLT...

上下游序列下载

upstream/downstream 最大各 10000 bp。负链基因会自动反向互补，使最终 FASTA 为转录方向 5′→3′。

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