Gene Card 基因详情

支持统一新 ID、NCBI Gene ID、GeneID、locus_tag、Transcript ID、Protein ID，以及已人工核对的文献基因名查询。页面会先解析到丹参统一基因，再整合坐标、序列、注释、亚细胞定位、EMS 突变和下载入口。

当前解析结果

`SmilChr07G002522`

染色体: Chr07 坐标: 23909002-23912885 链方向: - 类型: protein_coding

基本信息

统一新 Gene ID	`SmilChr07G002522`
名称	SmilChr07G002522
描述	ATP-citrate synthase alpha chain protein 1
染色体 / SeqID	Chr07 / NC_080393.1
坐标与链方向	23909002 - 23912885 / `-`

ID 对照

NCBI Gene ID	`LOC130993598`
GeneID	`130993598`
locus_tag	`-`
NCBI Name	`LOC130993598`
原始查询	`SmilChr07G002522`

查看完整 ID 对照表

功能注释

来源	GFF basic annotation; NCBI GO GAF; KEGG smil; Pfam-A/HMMER; Arabidopsis/Rice homolog
描述	ATP-citrate synthase alpha chain protein 1
产物	ATP-citrate synthase alpha chain protein 1
Arabidopsis	`AT1G10670` (ACLA-1) ATP-citrate lyase A-1 [Source:NCBI gene (formerly Entrezgene);Acc:837610] identity=85.1; qcov=1; evalue=0; confidence=high
Rice	`Os12g0566300` (ACLA-3) - identity=82; qcov=1; evalue=0; confidence=high
GO	GO:0004775 (succinate-CoA ligase (ADP-forming) activity); GO:0006099 (tricarboxylic acid cycle); GO:0006104 (succinyl-CoA metabolic process); GO:0042709 (succinate-CoA ligase complex)
KEGG	smil00020 (Citrate cycle (TCA cycle) - Salvia miltiorrhiza (redroot sage)); smil01100 (Metabolic pathways - Salvia miltiorrhiza (redroot sage)); smil01110 (Biosynthesis of secondary metabolites - Salvia miltiorrhiza (redroot sage))
Pfam	PF08442 (ATP-grasp_2); PF16114 (Citrate_bind); PF24948 (Citrate_synth_N)
InterPro	-
eggNOG	-
NR	GeneID:130993598

打开注释模块

亚细胞定位 Top 5

Rank	定位位置	中文	Score	Protein ID
1	Cytosol	细胞质基质	1.00000	`XP_057774514.1`
2	Cytoplasm	细胞质	0.80000	`XP_057774515.1`
3	Nucleoplasm	核质	0.20000	`XP_057774514.1`
4	Nucleus	细胞核	0.00000	`XP_057774514.1`
5	Chromosome	染色体	0.00000	`XP_057774514.1`

进入亚细胞定位查询

EMS 诱变突变

下表显示该基因在丹参 EMS 材料中的前 12 个候选突变；完整结果可进入 EMS 突变库继续筛选或下载。

位置	REF	ALT	类型	影响	携带材料数	材料
`Chr7:23909383`	`C`	`CT`	1bp_insertion	frameshift_variant	86	A10,A18,A23,A5,A8,B101,B108,B11,B114,B118,B119,B120,B121,B124,B125,B128,B129,B13,B130,B132,B134,B136,B14,B15,B17,B19,B2,B25,B27,B29,B30,B33,B38,B39,B4,B42,B54,B55,B63,B64,B66,B69,B76,B78,B79,B80,B83,B88,B89,B90,B92,B94,B95,B97,C10,C17,C18,C19,C2,C23,C25,C27,C30,C33,C36,C38,C39,C43,C45,C46,C49,C56,C60,C61,C68,C73,C76,C77,C81,C84,C86,C87,D10,D3,D6,D9
`Chr7:23909432`	`GAT`	`G`	2bp_deletion	frameshift_variant	72	A11,A13,A14,A23,A4,B101,B103,B11,B113,B114,B119,B120,B121,B127,B128,B13,B130,B131,B132,B136,B14,B17,B2,B23,B29,B30,B38,B39,B4,B42,B5,B54,B65,B66,B77,B79,B83,B87,B89,B9,B90,B94,B97,C10,C11,C13,C18,C2,C23,C25,C27,C38,C39,C41,C43,C45,C46,C49,C56,C63,C65,C66,C68,C72,C74,C81,C84,C86,C87,D10,D2,D9
`Chr7:23909884`	`G`	`A`	EMS_canonical_SNV	CDS_variant	1	C72
`Chr7:23910128`	`G`	`A`	EMS_canonical_SNV	CDS_variant	2	C46,C82
`Chr7:23910628`	`G`	`A`	EMS_canonical_SNV	CDS_variant	3	B106,C18,D11
`Chr7:23911017`	`G`	`A`	EMS_canonical_SNV	CDS_variant	2	B14,C39
`Chr7:23912450`	`C`	`T`	EMS_canonical_SNV	CDS_variant	3	C70,C72,D1

进入 EMS 突变库

预测功能结构域

结构域结果来自 Pfam-A HMM 数据库和 HMMER hmmscan；位置为对应蛋白序列上的氨基酸坐标。

XP_057774514.1

429 aa

214

429

Citrate_synth_N

ATP-grasp_2

Citrate_bind

PF24948 Citrate_synth_N 2-230 aa PF08442 ATP-grasp_2 6-203 aa PF16114 Citrate_bind 241-402 aa

XP_057774515.1

423 aa

212

423

Citrate_synth_N

ATP-grasp_2

Citrate_bind

PF24948 Citrate_synth_N 2-230 aa PF08442 ATP-grasp_2 6-203 aa PF16114 Citrate_bind 241-417 aa

Protein ID	来源	结构域编号	结构域名称	类型	起始 aa	终止 aa	E-value	Score	说明
`XP_057774514.1`	Pfam	`PF24948`	Citrate_synth_N	Domain	2	230	1.5e-74	251.0	ATP-citrate synthase ATP-grasp domain
`XP_057774514.1`	Pfam	`PF08442`	ATP-grasp_2	Domain	6	203	1.4e-15	58.2	ATP-grasp domain
`XP_057774514.1`	Pfam	`PF16114`	Citrate_bind	Domain	241	402	4.7e-76	255.0	ATP citrate lyase citrate-binding
`XP_057774515.1`	Pfam	`PF24948`	Citrate_synth_N	Domain	2	230	1.4e-74	251.1	ATP-citrate synthase ATP-grasp domain
`XP_057774515.1`	Pfam	`PF08442`	ATP-grasp_2	Domain	6	203	1.4e-15	58.2	ATP-grasp domain
`XP_057774515.1`	Pfam	`PF16114`	Citrate_bind	Domain	241	417	2.4e-83	278.7	ATP citrate lyase citrate-binding

cDNA / CDS / Protein 序列

下载基因组 DNA（仅基因区域）

每个公开基因均提供参考注释对应的转录本序列；蛋白编码基因另提供 CDS 和蛋白序列。非编码 RNA 不适用 CDS 或蛋白下载。真实 accession 的版本后缀予以保留。

cDNA

2 records

下载 cDNA FASTA

XM_057918532.1
TTTTCTTTTTTGGAAGGAAACTAAAAATAAGTTAAAATAAATAAGTAATTTAGTATTGCATTTCATGGAATCATGTTTGTCTAACTATAAATATTGGTAGGTGGATTACAAGATTACAAGCTTTGAGTGTTGAGTCATACTAGTCTGCCAGTGTGTGCGCACCAGAAAATTCTTGCAACCTCCTCTGCGCATTCCTTCAATCAGTTAAAAAGGAAAAATGGCGAGGAAGAAGATCAGAGAGTATGACTCCAAGAGACTGT...

XM_057918531.1
TTAGTATTGCATTTCATGGAATCATGTTTGTCTAACTATAAATATTGGTAGGTGGATTACAAGATTACAAGCTTTGAGTGTTGAGTCATACTAGTCTGCCAGTGTGTGCGCACCAGAAAATTCTTGCAACCTCCTCTGCGCATTCCTTCAATCAGTTAAAAAGGAAAAATGGCGAGGAAGAAGATCAGAGAGTATGACTCCAAGAGACTGTTGAAGGAGCATTTCAAGAGGATTTCTGGATCCGATTTGGAAATCAAATC...

CDS

2 records

下载 CDS FASTA

LOC130993598
ATGGCGAGGAAGAAGATCAGAGAGTATGACTCCAAGAGACTGTTGAAGGAGCATTTCAAGAGGATTTCTGGATCCGATTTGGAAATCAAATCTGCCCAGGTGACCGAGTCTACTGACTTTAATCAACTAGTGGACAAGGAGCCCTGGCTTTCATCTACAAGATTGGTTGTTAAACCAGATATGCTGTTTGGGAAACGTGGTAAAAGTGGTCTTGTTGCTTTGAACCTGGATTTGGCTGGAGTTGCTGCTTTTGTGAAAGA...

Protein

2 records

下载 Protein FASTA

XP_057774514.1
MARKKIREYDSKRLLKEHFKRISGSDLEIKSAQVTESTDFNQLVDKEPWLSSTRLVVKPDMLFGKRGKSGLVALNLDLAGVAAFVKERLGKEVEMGGCKGPITTFIVEPFIPHNEEFYLNIVSDRLGCSISFSECGGIDIEENWDKVKTIFVPTGVSFTSELCAPLVATLPLEVKPVIEEFITFIYALFLDLDFTFLEMNPFTLVNGKPYPLDMRGELDDTAAFKNFKKWGNIEFPMPFGRVMSPTESFIHGLDEKTSAS...

XP_057774515.1
MARKKIREYDSKRLLKEHFKRISGSDLEIKSAQVTESTDFNQLVDKEPWLSSTRLVVKPDMLFGKRGKSGLVALNLDLAGVAAFVKERLGKEVEMGGCKGPITTFIVEPFIPHNEEFYLNIVSDRLGCSISFSECGGIDIEENWDKVKTIFVPTGVSFTSELCAPLVATLPLEVKPVIEEFITFIYALFLDLDFTFLEMNPFTLVNGKPYPLDMRGELDDTAAFKNFKKWGNIEFPMPFGRVMSPTESFIHGLDEKTSAS...

上下游序列下载

upstream/downstream 最大各 10000 bp。负链基因会自动反向互补，使最终 FASTA 为转录方向 5′→3′。

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