Gene Card 基因详情

支持统一新 ID、NCBI Gene ID、GeneID、locus_tag、Transcript ID、Protein ID，以及已人工核对的文献基因名查询。页面会先解析到丹参统一基因，再整合坐标、序列、注释、亚细胞定位、EMS 突变和下载入口。

当前解析结果

`SmilChr07G002583`

染色体: Chr07 坐标: 24713350-24715964 链方向: - 类型: protein_coding

基本信息

统一新 Gene ID	`SmilChr07G002583`
名称	SmilChr07G002583
描述	protein-S-isoprenylcysteine O-methyltransferase A-like
染色体 / SeqID	Chr07 / NC_080393.1
坐标与链方向	24713350 - 24715964 / `-`

ID 对照

NCBI Gene ID	`LOC130993651`
GeneID	`130993651`
locus_tag	`-`
NCBI Name	`LOC130993651`
原始查询	`SmilChr07G002583`

查看完整 ID 对照表

功能注释

来源	GFF basic annotation; NCBI GO GAF; KEGG smil; Pfam-A/HMMER; Arabidopsis/Rice homolog
描述	protein-S-isoprenylcysteine O-methyltransferase A-like
产物	protein-S-isoprenylcysteine O-methyltransferase A-like
Arabidopsis	`AT5G08335` (ATSTE14B) Isoprenylcysteine carboxyl methyltransferase (ICMT) family [Source:NCBI gene (formerly Entrezgene);Acc:830731] identity=57.9; qcov=1; evalue=2.77e-87; confidence=high
Rice	`Os04g0602900` - identity=56.3; qcov=0.36; evalue=1.61e-23; confidence=low
GO	GO:0004671 (protein C-terminal S-isoprenylcysteine carboxyl O-methyltransferase activity); GO:0005783 (endoplasmic reticulum); GO:0006481 (C-terminal protein methylation); GO:0016020 (membrane)
KEGG	smil00900 (Terpenoid backbone biosynthesis - Salvia miltiorrhiza (redroot sage)); smil01110 (Biosynthesis of secondary metabolites - Salvia miltiorrhiza (redroot sage))
Pfam	PF04140 (ICMT); PF04191 (PEMT)
InterPro	-
eggNOG	-
NR	GeneID:130993651

打开注释模块

亚细胞定位 Top 5

Rank	定位位置	中文	Score	Protein ID
1	Endoplasmic reticulum	内质网	1.00000	`XP_057774613.1`
2	Endoplasmic reticulum membrane	内质网膜	1.00000	`XP_057774613.1`
3	Nucleus	细胞核	0.00000	`XP_057774613.1`
4	Chromosome	染色体	0.00000	`XP_057774613.1`
5	Centromere	着丝粒	0.00000	`XP_057774613.1`

进入亚细胞定位查询

EMS 诱变突变

下表显示该基因在丹参 EMS 材料中的前 12 个候选突变；完整结果可进入 EMS 突变库继续筛选或下载。

位置	REF	ALT	类型	影响	携带材料数	材料
`Chr7:24713758`	`C`	`T`	EMS_canonical_SNV	CDS_variant	1	C61
`Chr7:24713778`	`C`	`T`	EMS_canonical_SNV	CDS_variant	5	B106,B140,B82,C18,C5
`Chr7:24713782`	`C`	`T`	EMS_canonical_SNV	CDS_variant	1	B69
`Chr7:24713908`	`G`	`A`	EMS_canonical_SNV	CDS_variant	4	B120,B48,B84,C50
`Chr7:24714150`	`G`	`A`	EMS_canonical_SNV	CDS_variant	1	C61
`Chr7:24714284`	`G`	`A`	EMS_canonical_SNV	CDS_variant	1	B132

进入 EMS 突变库

预测功能结构域

结构域结果来自 Pfam-A HMM 数据库和 HMMER hmmscan；位置为对应蛋白序列上的氨基酸坐标。

XP_057774613.1

197 aa

197

PEMT

ICMT

PF04191 PEMT 81-180 aa PF04140 ICMT 83-174 aa

XP_057774614.1

197 aa

197

PEMT

ICMT

PF04191 PEMT 81-180 aa PF04140 ICMT 83-174 aa

XP_057774615.1

197 aa

197

PEMT

ICMT

PF04191 PEMT 81-180 aa PF04140 ICMT 83-174 aa

Protein ID	来源	结构域编号	结构域名称	类型	起始 aa	终止 aa	E-value	Score	说明
`XP_057774613.1`	Pfam	`PF04191`	PEMT	Family	81	180	4.8e-12	47.0	Phospholipid methyltransferase
`XP_057774613.1`	Pfam	`PF04140`	ICMT	Family	83	174	6.6e-30	104.1	Isoprenylcysteine carboxyl methyltransferase (ICMT) family
`XP_057774614.1`	Pfam	`PF04191`	PEMT	Family	81	180	4.8e-12	47.0	Phospholipid methyltransferase
`XP_057774614.1`	Pfam	`PF04140`	ICMT	Family	83	174	6.6e-30	104.1	Isoprenylcysteine carboxyl methyltransferase (ICMT) family
`XP_057774615.1`	Pfam	`PF04191`	PEMT	Family	81	180	4.8e-12	47.0	Phospholipid methyltransferase
`XP_057774615.1`	Pfam	`PF04140`	ICMT	Family	83	174	6.6e-30	104.1	Isoprenylcysteine carboxyl methyltransferase (ICMT) family

cDNA / CDS / Protein 序列

下载基因组 DNA（仅基因区域）

每个公开基因均提供参考注释对应的转录本序列；蛋白编码基因另提供 CDS 和蛋白序列。非编码 RNA 不适用 CDS 或蛋白下载。真实 accession 的版本后缀予以保留。

cDNA

3 records

下载 cDNA FASTA

XM_057918630.1
CTATTTGCCACTTCCCCCTTATTACTATTACTTTCATATTTTCATCGAGACACATCATTTTTATTTATAGTTCATATATTTAGCAGGTATTTAACTCAATATTTACTTATTTGTGCAATTTTCACATGACTTTCAACTATTACAACTTTTTTGAGTTAGAAAAGAAAGGGTCCATGATGATTGAACCAATAACCTTTCTTGTTAGTACTTTTTTGTTATTCTAAAATTATTATCAACTTATCTTAGTGATAGCCATATTT...

XM_057918631.1
CATTTAAAATATGGGGAAGCTAAAAACACAAACGGAAAATAAATATTTTTGTTTCAACAAATATGTGATCATACAGAATCTCTGGATCACCGCCTTTTGATGAAATCCGGAAGAAATTTTTAGACCAAAAAACAAACAAACTATCCTTTCCTCGCCATTGAGTTTTTTCAAACCTCCACGATTCAAAATACGAAGGAAATTCAACCTTTATCATGGGTGTCATTGATTGCACATAGATCGACTGGCTGAAATGTTTGCCG...

CDS

3 records

下载 CDS FASTA

LOC130993651
ATGTCGGAGATCTTCAGCTTCACGGCTTTCAGACATATATCGCAAATGCTCTTTGCGACATTCTTCTTTCACAGTTCTGAGTTTCTTCTAGCAGTTTACTTCCACGGGATTCACAAAGTAACTCTGAATTCCCTTTTACTCAGCATAGACTATGTTATGGCAATGATCTGCTCCCTGATAGAGTACTTGATTGAAGTTCATTTCTTCCCGGAGATGAAGGAACAGTGGGAAGTAAGCAACATGGGTCTTGCCTTGGTAGT...

Protein

3 records

下载 Protein FASTA

XP_057774613.1
MSEIFSFTAFRHISQMLFATFFFHSSEFLLAVYFHGIHKVTLNSLLLSIDYVMAMICSLIEYLIEVHFFPEMKEQWEVSNMGLALVVVGEVIRKLAIITAGRSFTHLIKKYIDDDHVLITHGLYKYVRHPSYCGFFIWSVGTQIMLCNPVCTLGFALVVWRFFQIRIPYEEFFLRQYFGSQYEAYARRTASGIPFVK

XP_057774614.1
MSEIFSFTAFRHISQMLFATFFFHSSEFLLAVYFHGIHKVTLNSLLLSIDYVMAMICSLIEYLIEVHFFPEMKEQWEVSNMGLALVVVGEVIRKLAIITAGRSFTHLIKKYIDDDHVLITHGLYKYVRHPSYCGFFIWSVGTQIMLCNPVCTLGFALVVWRFFQIRIPYEEFFLRQYFGSQYEAYARRTASGIPFVK

上下游序列下载

upstream/downstream 最大各 10000 bp。负链基因会自动反向互补，使最终 FASTA 为转录方向 5′→3′。

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