Gene Card 基因详情

支持统一新 ID、NCBI Gene ID、GeneID、locus_tag、Transcript ID、Protein ID，以及已人工核对的文献基因名查询。页面会先解析到丹参统一基因，再整合坐标、序列、注释、亚细胞定位、EMS 突变和下载入口。

当前解析结果

`SmilChr07G002613`

染色体: Chr07 坐标: 25180758-25184749 链方向: - 类型: protein_coding

基本信息

统一新 Gene ID	`SmilChr07G002613`
名称	SmilChr07G002613
描述	cyclin-D1-1
染色体 / SeqID	Chr07 / NC_080393.1
坐标与链方向	25180758 - 25184749 / `-`

ID 对照

NCBI Gene ID	`LOC130993678`
GeneID	`130993678`
locus_tag	`-`
NCBI Name	`LOC130993678`
原始查询	`SmilChr07G002613`

查看完整 ID 对照表

功能注释

来源	GFF basic annotation; NCBI GO GAF; Pfam-A/HMMER; Arabidopsis/Rice homolog
描述	cyclin-D1-1
产物	cyclin-D1-1
Arabidopsis	`AT1G70210` (CYCD1;1) CYCLIN D1;1 [Source:NCBI gene (formerly Entrezgene);Acc:843357] identity=53.9; qcov=1.02; evalue=5.94e-114; confidence=high
Rice	`Os09g0382300` (CycD1) - identity=46.8; qcov=0.82; evalue=3.33e-70; confidence=high
GO	GO:0000079 (regulation of cyclin-dependent protein serine/threonine kinase activity); GO:0000307 (cyclin-dependent protein kinase holoenzyme complex); GO:0005634 (nucleus); GO:0005737 (cytoplasm); GO:0016538 (cyclin-dependent protein serine/threonine kinase regulator activity); GO:0044772 (mitotic cell cycle phase transition)
KEGG	-
Pfam	PF00134 (Cyclin_N); PF02984 (Cyclin_C)
InterPro	-
eggNOG	-
NR	GeneID:130993678

打开注释模块

亚细胞定位 Top 5

Rank	定位位置	中文	Score	Protein ID
1	Nucleus	细胞核	1.00000	`XP_057774664.1`
2	Chromosome	染色体	0.00000	`XP_057774664.1`
3	Centromere	着丝粒	0.00000	`XP_057774664.1`
4	Chromatin	染色质	0.00000	`XP_057774664.1`
5	Telomere	端粒	0.00000	`XP_057774664.1`

进入亚细胞定位查询

EMS 诱变突变

下表显示该基因在丹参 EMS 材料中的前 12 个候选突变；完整结果可进入 EMS 突变库继续筛选或下载。

位置	REF	ALT	类型	影响	携带材料数	材料
`Chr7:25181722`	`C`	`T`	EMS_canonical_SNV	CDS_variant	1	C42
`Chr7:25181734`	`C`	`T`	EMS_canonical_SNV	CDS_variant	1	B122
`Chr7:25181744`	`G`	`A`	EMS_canonical_SNV	CDS_variant	4	B121,B127,B25,D8
`Chr7:25181888`	`GTT`	`G`	2bp_deletion	frameshift_variant	94	A1,A13,A16,A18,A21,A3,A4,B1,B101,B105,B108,B11,B112,B115,B123,B125,B126,B13,B131,B133,B135,B137,B14,B17,B18,B22,B23,B29,B30,B31,B34,B4,B41,B45,B48,B50,B52,B57,B58,B66,B69,B7,B72,B74,B78,B80,B84,B85,B86,B87,B89,B9,B93,B94,B98,C1,C10,C11,C18,C19,C2,C20,C21,C23,C24,C27,C31,C33,C35,C39,C4,C41,C42,C46,C47,C5,C58,C6,C62,C63,C64,C66,C70,C71,C72,C73,C77,C83,C84,C85,C9,D11,D2,D5
`Chr7:25181891`	`T`	`TG`	1bp_insertion	frameshift_variant	118	A11,A13,A15,A16,A18,A21,A22,A23,A24,A25,A3,A4,A7,B1,B102,B105,B106,B108,B110,B112,B114,B115,B119,B12,B120,B121,B123,B124,B126,B128,B13,B130,B131,B135,B137,B138,B15,B18,B19,B2,B20,B22,B23,B26,B27,B28,B29,B31,B32,B38,B39,B4,B40,B41,B46,B47,B56,B58,B59,B6,B61,B63,B66,B69,B7,B78,B79,B80,B87,B9,B94,B95,B96,B98,C10,C14,C17,C2,C20,C21,C22,C24,C27,C28,C29,C31,C32,C33,C35,C39,C4,C40,C46,C47,C49,C50,C51,C52,C57,C63,C64,C66,C68,C72,C74,C77,C78,C8,C80,C81,C85,C86,C9,D11,D2,D3,D5,D8
`Chr7:25182472`	`G`	`GGT`	2bp_insertion	frameshift_variant	6	B55,B60,B87,C24,C73,C8
`Chr7:25182476`	`CTT`	`C`	2bp_deletion	frameshift_variant	6	B55,B60,B87,C24,C73,C8
`Chr7:25182609`	`C`	`T`	EMS_canonical_SNV	CDS_variant	1	B73
`Chr7:25183832`	`G`	`A`	EMS_canonical_SNV	CDS_variant	3	B121,B18,B42
`Chr7:25184316`	`G`	`A`	EMS_canonical_SNV	CDS_variant	1	B93
`Chr7:25184347`	`G`	`A`	EMS_canonical_SNV	CDS_variant	2	B12,B55
`Chr7:25184352`	`G`	`A`	EMS_canonical_SNV	CDS_variant	3	B27,B44,D7

进入 EMS 突变库

预测功能结构域

结构域结果来自 Pfam-A HMM 数据库和 HMMER hmmscan；位置为对应蛋白序列上的氨基酸坐标。

XP_057774664.1

355 aa

178

355

Cyclin_N

Cyclin_C

PF00134 Cyclin_N 64-174 aa PF02984 Cyclin_C 177-264 aa

XP_057774665.1

328 aa

164

328

Cyclin_N

Cyclin_C

PF00134 Cyclin_N 64-174 aa PF02984 Cyclin_C 177-284 aa

Protein ID	来源	结构域编号	结构域名称	类型	起始 aa	终止 aa	E-value	Score	说明
`XP_057774664.1`	Pfam	`PF00134`	Cyclin_N	Domain	64	174	2.1e-29	102.6	Cyclin, N-terminal domain
`XP_057774664.1`	Pfam	`PF02984`	Cyclin_C	Domain	177	264	5.9e-10	39.9	Cyclin, C-terminal domain
`XP_057774665.1`	Pfam	`PF00134`	Cyclin_N	Domain	64	174	1.8e-29	102.8	Cyclin, N-terminal domain
`XP_057774665.1`	Pfam	`PF02984`	Cyclin_C	Domain	177	284	5.7e-14	52.9	Cyclin, C-terminal domain

cDNA / CDS / Protein 序列

下载基因组 DNA（仅基因区域）

每个公开基因均提供参考注释对应的转录本序列；蛋白编码基因另提供 CDS 和蛋白序列。非编码 RNA 不适用 CDS 或蛋白下载。真实 accession 的版本后缀予以保留。

cDNA

2 records

下载 cDNA FASTA

XM_057918682.1
GAAATAAAATAAAAAGATGGAAATCGTATCGACAAAAAATAAAAAAATACAAGCCAATTCTATCTATCTATATATCCGACGCAAACAGGAGAGACTCTAAACCCACACACACATTCTAACCTAGCACACACCTCCCGCCGCCTACATTTCCGGCGACTATCCCGATGAATATCCGGCAATAATCGAAGCCAAAAATTTCCAGCTGGAATGATCAGAAGAGATTAACGGCCGATCATCGGTGGTCGCATTCGCCACTCGCT...

XM_057918681.1
GAAATAAAATAAAAAGATGGAAATCGTATCGACAAAAAATAAAAAAATACAAGCCAATTCTATCTATCTATATATCCGACGCAAACAGGAGAGACTCTAAACCCACACACACATTCTAACCTAGCACACACCTCCCGCCGCCTACATTTCCGGCGACTATCCCGATGAATATCCGGCAATAATCGAAGCCAAAAATTTCCAGCTGGAATGATCAGAAGAGATTAACGGCCGATCATCGGTGGTCGCATTCGCCACTCGCT...

CDS

2 records

下载 CDS FASTA

LOC130993678
ATGTCACTGTCGTGCTCCGACTGCTTCTCCGACCTTCTCTGCGGCGAGGACTCCAATATCATCTTCGCCGCCGGCGTAGATGACTTGCCGGAATATTTATCAGACATCGACTCCGGCCCGCCGGACGTCGAGGAATCCATCGCCGGACTTTTAGAAGACGAGAGAGATCTCGCCGGGATTAATTCGCCTCTTTCTCATCAATCCATCGATGAATCTACAAGGGCGGAATCCGTTGCATGGATTCTCAAGGTACAACGGTA...

Protein

2 records

下载 Protein FASTA

XP_057774664.1
MSLSCSDCFSDLLCGEDSNIIFAAGVDDLPEYLSDIDSGPPDVEESIAGLLEDERDLAGINSPLSHQSIDESTRAESVAWILKVQRYYGFQPLTAYLSVNYFDRFLYSHHLPKMNGWPLQLLSVACMSLAAKMEEPLVPSLLDLQVESAKFIFEPKNIQRMELLVLRVLDWRLRSISPFCYLSFFAVKIDPTATYTGFLVSRAKEIILSTMQESSFLEYRPSCVAAAAILCAANDLPKFSLISAQHAESWSDGLDKVRKI...

XP_057774665.1
MSLSCSDCFSDLLCGEDSNIIFAAGVDDLPEYLSDIDSGPPDVEESIAGLLEDERDLAGINSPLSHQSIDESTRAESVAWILKVQRYYGFQPLTAYLSVNYFDRFLYSHHLPKMNGWPLQLLSVACMSLAAKMEEPLVPSLLDLQVESAKFIFEPKNIQRMELLVLRVLDWRLRSISPFCYLSFFAVKIDPTATYTGFLVSRAKEIILSTMQESSFLEYRPSCVAAAAILCAANDLPKFSLISAQHAESWSDGLDKESIT...

上下游序列下载

upstream/downstream 最大各 10000 bp。负链基因会自动反向互补，使最终 FASTA 为转录方向 5′→3′。

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