Gene Card 基因详情

支持统一新 ID、NCBI Gene ID、GeneID、locus_tag、Transcript ID、Protein ID，以及已人工核对的文献基因名查询。页面会先解析到丹参统一基因，再整合坐标、序列、注释、亚细胞定位、EMS 突变和下载入口。

当前解析结果

`SmilChr07G002620`

染色体: Chr07 坐标: 25274403-25278771 链方向: - 类型: protein_coding

基本信息

统一新 Gene ID	`SmilChr07G002620`
名称	SmilChr07G002620
描述	DNA polymerase lambda
染色体 / SeqID	Chr07 / NC_080393.1
坐标与链方向	25274403 - 25278771 / `-`

ID 对照

NCBI Gene ID	`LOC130993682`
GeneID	`130993682`
locus_tag	`-`
NCBI Name	`LOC130993682`
原始查询	`SmilChr07G002620`

查看完整 ID 对照表

功能注释

来源	GFF basic annotation; NCBI GO GAF; KEGG smil; Pfam-A/HMMER; Arabidopsis/Rice homolog
描述	DNA polymerase lambda
产物	DNA polymerase lambda
Arabidopsis	`AT1G10520` (Pol{lambda}) DNA polymerase lambda (POLL) [Source:NCBI gene (formerly Entrezgene);Acc:837592] identity=65.2; qcov=1.01; evalue=0; confidence=high
Rice	`Os06g0237200` (OsPol) - identity=59.1; qcov=0.991; evalue=0; confidence=high
GO	GO:0003677 (DNA binding); GO:0003887 (DNA-directed DNA polymerase activity); GO:0005634 (nucleus); GO:0006303 (double-strand break repair via nonhomologous end joining)
KEGG	smil03410 (Base excision repair - Salvia miltiorrhiza (redroot sage)); smil03450 (Non-homologous end-joining - Salvia miltiorrhiza (redroot sage))
Pfam	PF00533 (BRCT); PF10391 (DNA_pol_lambd_f); PF14716 (HHH_8); PF14791 (DNA_pol_B_thumb); PF14792 (DNA_pol_B_palm)
InterPro	-
eggNOG	-
NR	GeneID:130993682

打开注释模块

亚细胞定位 Top 5

Rank	定位位置	中文	Score	Protein ID
1	Nucleus	细胞核	1.00000	`XP_057774669.1`
2	Nucleoplasm	核质	1.00000	`XP_057774669.1`
3	Nuclear body	核内小体	0.40000	`XP_057774669.1`
4	Nucleolus	核仁	0.20000	`XP_057774669.1`
5	Chromosome	染色体	0.00000	`XP_057774669.1`

进入亚细胞定位查询

EMS 诱变突变

下表显示该基因在丹参 EMS 材料中的前 12 个候选突变；完整结果可进入 EMS 突变库继续筛选或下载。

位置	REF	ALT	类型	影响	携带材料数	材料
`Chr7:25275508`	`C`	`T`	EMS_canonical_SNV	CDS_variant	1	B37
`Chr7:25277455`	`G`	`A`	EMS_canonical_SNV	CDS_variant	1	B93
`Chr7:25277515`	`C`	`T`	EMS_canonical_SNV	CDS_variant	4	B2,B22,C32,C68
`Chr7:25277530`	`C`	`T`	EMS_canonical_SNV	CDS_variant	3	B27,B44,D7
`Chr7:25277750`	`G`	`A`	EMS_canonical_SNV	CDS_variant	3	B27,B44,D7
`Chr7:25277783`	`C`	`T`	EMS_canonical_SNV	CDS_variant	4	B100,B136,B99,D4
`Chr7:25277858`	`T`	`TG`	1bp_insertion	frameshift_variant	100	A14,A20,A21,A9,B100,B101,B104,B106,B108,B11,B111,B113,B118,B125,B130,B131,B134,B136,B137,B139,B140,B16,B17,B2,B22,B24,B29,B30,B31,B33,B34,B36,B37,B45,B48,B49,B50,B59,B64,B66,B67,B68,B69,B72,B73,B8,B80,B81,B88,B89,B91,B94,B98,C1,C11,C12,C14,C15,C16,C18,C19,C2,C21,C23,C25,C27,C30,C31,C32,C34,C36,C37,C39,C41,C42,C44,C46,C48,C49,C5,C53,C54,C58,C6,C60,C61,C62,C65,C67,C68,C69,C73,C75,C82,C83,C85,D11,D2,D5,D6
`Chr7:25277862`	`GA`	`G`	1bp_deletion	frameshift_variant	100	A14,A20,A21,A9,B100,B101,B104,B106,B108,B11,B111,B113,B118,B125,B130,B131,B134,B136,B137,B139,B140,B16,B17,B2,B22,B24,B29,B30,B31,B33,B34,B36,B37,B45,B48,B49,B50,B59,B64,B66,B67,B68,B69,B72,B73,B8,B80,B81,B88,B89,B91,B94,B98,C1,C11,C12,C14,C15,C16,C18,C19,C2,C21,C23,C25,C27,C30,C31,C32,C34,C36,C37,C39,C41,C42,C44,C46,C48,C49,C5,C53,C54,C58,C6,C60,C61,C62,C65,C67,C68,C69,C73,C75,C82,C83,C85,D11,D2,D5,D6
`Chr7:25277893`	`G`	`A`	EMS_canonical_SNV	CDS_variant	1	D11
`Chr7:25277965`	`C`	`T`	EMS_canonical_SNV	CDS_variant	1	B132
`Chr7:25278011`	`GC`	`G`	1bp_deletion	frameshift_variant	61	A10,A11,A16,A18,A23,A24,A7,B110,B118,B12,B122,B126,B128,B130,B131,B132,B137,B15,B23,B28,B3,B40,B46,B47,B55,B56,B6,B63,B65,B66,B70,B71,B73,B83,B93,B94,B96,C12,C13,C16,C28,C3,C34,C37,C40,C44,C55,C56,C57,C64,C66,C67,C7,C76,C78,C80,C81,C83,C84,C86,D2
`Chr7:25278450`	`G`	`GC`	1bp_insertion	frameshift_variant	89	A14,A20,A21,A24,B101,B106,B108,B11,B111,B113,B118,B125,B129,B130,B131,B134,B136,B137,B139,B140,B16,B17,B2,B22,B24,B29,B30,B31,B33,B34,B36,B37,B45,B48,B49,B59,B6,B66,B67,B68,B69,B72,B73,B8,B80,B81,B88,B91,B94,B98,C11,C12,C14,C18,C2,C23,C25,C30,C32,C35,C36,C39,C40,C41,C42,C46,C49,C5,C53,C54,C60,C61,C62,C65,C67,C68,C69,C70,C71,C73,C75,C77,C81,C82,C85,D10,D5,D6,D9

进入 EMS 突变库

预测功能结构域

结构域结果来自 Pfam-A HMM 数据库和 HMMER hmmscan；位置为对应蛋白序列上的氨基酸坐标。

XP_057774669.1

543 aa

272

543

BRCT

HHH_8

DNA_pol_lambd_f

DNA_pol_B_palm

DNA_pol_B_thumb

PF00533 BRCT 16-94 aa PF14716 HHH_8 215-284 aa PF10391 DNA_pol_lambd_f 301-347 aa PF14792 DNA_pol_B_palm 350-464 aa PF14791 DNA_pol_B_thumb 471-542 aa

Protein ID	来源	结构域编号	结构域名称	类型	起始 aa	终止 aa	E-value	Score	说明
`XP_057774669.1`	Pfam	`PF00533`	BRCT	Domain	16	94	1.8e-09	38.3	BRCA1 C Terminus (BRCT) domain
`XP_057774669.1`	Pfam	`PF14716`	HHH_8	Domain	215	284	3.2e-17	63.4	Helix-hairpin-helix domain
`XP_057774669.1`	Pfam	`PF10391`	DNA_pol_lambd_f	Domain	301	347	4e-19	68.9	Fingers domain of DNA polymerase lambda
`XP_057774669.1`	Pfam	`PF14792`	DNA_pol_B_palm	Domain	350	464	1.1e-27	97.3	DNA polymerase beta palm
`XP_057774669.1`	Pfam	`PF14791`	DNA_pol_B_thumb	Family	471	542	1.3e-18	67.3	DNA polymerase beta thumb

cDNA / CDS / Protein 序列

下载基因组 DNA（仅基因区域）

每个公开基因均提供参考注释对应的转录本序列；蛋白编码基因另提供 CDS 和蛋白序列。非编码 RNA 不适用 CDS 或蛋白下载。真实 accession 的版本后缀予以保留。

cDNA

1 records

下载 cDNA FASTA

XM_057918686.1
GGAACACACATAAAAATGGCGCCAAAGCCTAAGAAGAAATCTCCACCGTCTGATCCTAACGGAGTATTTTCCGGAATCACCGTCTTCCTTATTGAAGCCGGCGTTCAACAGCGTCGCCTTCAGATTTGGAAGCAAAAACTGGTGCAATTGGGGGCTAAGATTGAGGAGAGTTTCTCCAAAAGGGTTACCCACATTTTTGCCGGCGGACGCGGATTCGCTTCTCAGAAAAGTAGGCAGCAGAACTTGAAGCGATTCAAAGG...

CDS

1 records

下载 CDS FASTA

LOC130993682
ATGGCGCCAAAGCCTAAGAAGAAATCTCCACCGTCTGATCCTAACGGAGTATTTTCCGGAATCACCGTCTTCCTTATTGAAGCCGGCGTTCAACAGCGTCGCCTTCAGATTTGGAAGCAAAAACTGGTGCAATTGGGGGCTAAGATTGAGGAGAGTTTCTCCAAAAGGGTTACCCACATTTTTGCCGGCGGACGCGGATTCGCTTCTCAGAAAAGTAGGCAGCAGAACTTGAAGCGATTCAAAGGGAAAATTTTGAACTA...

Protein

1 records

下载 Protein FASTA

XP_057774669.1
MAPKPKKKSPPSDPNGVFSGITVFLIEAGVQQRRLQIWKQKLVQLGAKIEESFSKRVTHIFAGGRGFASQKSRQQNLKRFKGKILNYQWIEDSLRAGEKVSEDPYVFSEDASKNCSSKVSEENLKHVDANLSYEDQLPSKKLKTCPQESETVESEERPRHPVDSAKCSPKSDNASGSSQSAGPISPEVTSLSLDGLNKDVSSSDTSSLYSPPDMNRNITEIFGKLIDIYRALGEDRRSFSYYKAIPVIEKLPFKIESADQ...

上下游序列下载

upstream/downstream 最大各 10000 bp。负链基因会自动反向互补，使最终 FASTA 为转录方向 5′→3′。

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JBrowse

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