Gene Card 基因详情

支持统一新 ID、NCBI Gene ID、GeneID、locus_tag、Transcript ID、Protein ID，以及已人工核对的文献基因名查询。页面会先解析到丹参统一基因，再整合坐标、序列、注释、亚细胞定位、EMS 突变和下载入口。

当前解析结果

`SmilChr07G002659`

染色体: Chr07 坐标: 25781401-25792752 链方向: - 类型: protein_coding

基本信息

统一新 Gene ID	`SmilChr07G002659`
名称	SmilChr07G002659
描述	paired amphipathic helix protein Sin3-like 3
染色体 / SeqID	Chr07 / NC_080393.1
坐标与链方向	25781401 - 25792752 / `-`

ID 对照

NCBI Gene ID	`LOC130993725`
GeneID	`130993725`
locus_tag	`-`
NCBI Name	`LOC130993725`
原始查询	`SmilChr07G002659`

查看完整 ID 对照表

功能注释

来源	GFF basic annotation; NCBI GO GAF; Pfam-A/HMMER; Arabidopsis/Rice homolog
描述	paired amphipathic helix protein Sin3-like 3
产物	paired amphipathic helix protein Sin3-like 3
Arabidopsis	`AT1G24190` (SNL3) SIN3-like 3 [Source:NCBI gene (formerly Entrezgene);Acc:839032] identity=46.4; qcov=1.05; evalue=0; confidence=high
Rice	`Os01g0109700` - identity=45.7; qcov=1.03; evalue=0; confidence=high
GO	GO:0000118 (histone deacetylase complex); GO:0000122 (negative regulation of transcription by RNA polymerase II); GO:0000785 (chromatin); GO:0003714 (transcription corepressor activity); GO:0016575 (GO:0016575)
KEGG	-
Pfam	PF02671 (PAH); PF08295 (Sin3_corepress); PF16879 (Sin3a_C)
InterPro	-
eggNOG	-
NR	GeneID:130993725

打开注释模块

亚细胞定位 Top 5

Rank	定位位置	中文	Score	Protein ID
1	Nucleus	细胞核	1.00000	`XP_057774745.1`
2	Chromosome	染色体	0.00000	`XP_057774745.1`
3	Centromere	着丝粒	0.00000	`XP_057774745.1`
4	Chromatin	染色质	0.00000	`XP_057774745.1`
5	Telomere	端粒	0.00000	`XP_057774745.1`

进入亚细胞定位查询

EMS 诱变突变

下表显示该基因在丹参 EMS 材料中的前 12 个候选突变；完整结果可进入 EMS 突变库继续筛选或下载。

位置	REF	ALT	类型	影响	携带材料数	材料
`Chr7:25782207`	`C`	`T`	EMS_canonical_SNV	CDS_variant	3	B32,C49,C50
`Chr7:25782353`	`G`	`A`	EMS_canonical_SNV	CDS_variant	1	D10
`Chr7:25783133`	`TGG`	`T`	2bp_deletion	frameshift_variant	132	A10,A13,A14,A15,A18,A19,A20,A21,A22,A24,A25,A4,A6,A7,A9,B1,B103,B104,B105,B112,B113,B114,B115,B117,B118,B120,B121,B123,B124,B125,B127,B13,B132,B133,B135,B18,B19,B20,B21,B22,B24,B25,B27,B30,B32,B33,B34,B36,B37,B38,B39,B4,B41,B42,B43,B44,B45,B46,B47,B5,B50,B54,B55,B6,B62,B63,B64,B67,B68,B75,B77,B79,B80,B82,B83,B85,B87,B88,B89,B9,B90,B91,B92,B95,B97,B98,C1,C10,C11,C18,C20,C22,C23,C24,C28,C35,C39,C40,C41,C44,C45,C48,C49,C5,C50,C52,C53,C54,C59,C6,C62,C67,C69,C7,C72,C74,C75,C76,C77,C79,C8,C80,C81,C85,C86,C9,D1,D11,D4,D6,D7,D9
`Chr7:25783137`	`A`	`AAT`	2bp_insertion	frameshift_variant	132	A10,A13,A14,A15,A18,A19,A20,A21,A22,A24,A25,A4,A6,A7,A9,B1,B103,B104,B105,B112,B113,B114,B115,B117,B118,B120,B121,B123,B124,B125,B127,B13,B132,B133,B135,B18,B19,B20,B21,B22,B24,B25,B27,B30,B32,B33,B34,B36,B37,B38,B39,B4,B41,B42,B43,B44,B45,B46,B47,B5,B50,B54,B55,B6,B62,B63,B64,B67,B68,B75,B77,B79,B80,B82,B83,B85,B87,B88,B89,B9,B90,B91,B92,B95,B97,B98,C1,C10,C11,C18,C20,C22,C23,C24,C28,C35,C39,C40,C41,C44,C45,C48,C49,C5,C50,C52,C53,C54,C59,C6,C62,C67,C69,C7,C72,C74,C75,C76,C77,C79,C8,C80,C81,C85,C86,C9,D1,D11,D4,D6,D7,D9
`Chr7:25783363`	`G`	`A`	EMS_canonical_SNV	CDS_variant	4	B103,B21,C70,C71
`Chr7:25784346`	`C`	`T`	EMS_canonical_SNV	CDS_variant	1	D10
`Chr7:25784363`	`C`	`T`	EMS_canonical_SNV	CDS_variant	1	D10
`Chr7:25784543`	`G`	`A`	EMS_canonical_SNV	CDS_variant	1	D10
`Chr7:25784650`	`G`	`A`	EMS_canonical_SNV	CDS_variant	1	D10
`Chr7:25784652`	`G`	`A`	EMS_canonical_SNV	CDS_variant	5	B140,B82,C2,C40,C55
`Chr7:25784902`	`G`	`A`	EMS_canonical_SNV	CDS_variant	5	B2,C28,C32,C46,C68
`Chr7:25787763`	`G`	`A`	EMS_canonical_SNV	CDS_variant	1	B140

进入 EMS 突变库

预测功能结构域

结构域结果来自 Pfam-A HMM 数据库和 HMMER hmmscan；位置为对应蛋白序列上的氨基酸坐标。

XP_057774745.1

1317 aa

658

1317

PAH

Sin3_corepress

Sin3a_C

PF02671 PAH 61-105 aa PF02671 PAH 147-191 aa PF08295 Sin3_corepress 441-532 aa PF16879 Sin3a_C 1043-1290 aa

XP_057774746.1

1301 aa

650

1301

PAH

Sin3_corepress

Sin3a_C

PF02671 PAH 61-105 aa PF02671 PAH 147-191 aa PF08295 Sin3_corepress 425-516 aa PF16879 Sin3a_C 1027-1274 aa

XP_057774747.1

1289 aa

644

1289

PAH

Sin3_corepress

Sin3a_C

PF02671 PAH 61-105 aa PF02671 PAH 147-191 aa PF08295 Sin3_corepress 441-532 aa PF16879 Sin3a_C 1015-1262 aa

XP_057774748.1

1276 aa

638

1276

PAH

Sin3_corepress

Sin3a_C

PF02671 PAH 20-64 aa PF02671 PAH 106-150 aa PF08295 Sin3_corepress 400-491 aa PF16879 Sin3a_C 1002-1249 aa

XP_057774749.1

1273 aa

636

1273

PAH

Sin3_corepress

Sin3a_C

PF02671 PAH 61-105 aa PF02671 PAH 147-191 aa PF08295 Sin3_corepress 425-516 aa PF16879 Sin3a_C 999-1246 aa

Protein ID	来源	结构域编号	结构域名称	类型	起始 aa	终止 aa	E-value	Score	说明
`XP_057774745.1`	Pfam	`PF02671`	PAH	Repeat	61	105	8.5e-36	122.1	Paired amphipathic helix repeat
`XP_057774745.1`	Pfam	`PF02671`	PAH	Repeat	147	191	8.5e-36	122.1	Paired amphipathic helix repeat
`XP_057774745.1`	Pfam	`PF08295`	Sin3_corepress	Domain	441	532	8.3e-33	113.1	Sin3 family co-repressor
`XP_057774745.1`	Pfam	`PF16879`	Sin3a_C	Family	1043	1290	1.3e-43	150.3	C-terminal domain of Sin3a protein
`XP_057774746.1`	Pfam	`PF02671`	PAH	Repeat	61	105	8.2e-36	122.2	Paired amphipathic helix repeat
`XP_057774746.1`	Pfam	`PF02671`	PAH	Repeat	147	191	8.2e-36	122.2	Paired amphipathic helix repeat
`XP_057774746.1`	Pfam	`PF08295`	Sin3_corepress	Domain	425	516	8.6e-33	113.0	Sin3 family co-repressor
`XP_057774746.1`	Pfam	`PF16879`	Sin3a_C	Family	1027	1274	1.3e-43	150.3	C-terminal domain of Sin3a protein
`XP_057774747.1`	Pfam	`PF02671`	PAH	Repeat	61	105	7.8e-36	122.3	Paired amphipathic helix repeat
`XP_057774747.1`	Pfam	`PF02671`	PAH	Repeat	147	191	7.8e-36	122.3	Paired amphipathic helix repeat
`XP_057774747.1`	Pfam	`PF08295`	Sin3_corepress	Domain	441	532	8.3e-33	113.1	Sin3 family co-repressor
`XP_057774747.1`	Pfam	`PF16879`	Sin3a_C	Family	1015	1262	1.1e-43	150.5	C-terminal domain of Sin3a protein
`XP_057774748.1`	Pfam	`PF02671`	PAH	Repeat	20	64	7.6e-36	122.3	Paired amphipathic helix repeat
`XP_057774748.1`	Pfam	`PF02671`	PAH	Repeat	106	150	7.6e-36	122.3	Paired amphipathic helix repeat
`XP_057774748.1`	Pfam	`PF08295`	Sin3_corepress	Domain	400	491	8.2e-33	113.1	Sin3 family co-repressor
`XP_057774748.1`	Pfam	`PF16879`	Sin3a_C	Family	1002	1249	2.1e-44	152.9	C-terminal domain of Sin3a protein
`XP_057774749.1`	Pfam	`PF02671`	PAH	Repeat	61	105	7.5e-36	122.3	Paired amphipathic helix repeat
`XP_057774749.1`	Pfam	`PF02671`	PAH	Repeat	147	191	7.5e-36	122.3	Paired amphipathic helix repeat
`XP_057774749.1`	Pfam	`PF08295`	Sin3_corepress	Domain	425	516	8.1e-33	113.1	Sin3 family co-repressor
`XP_057774749.1`	Pfam	`PF16879`	Sin3a_C	Family	999	1246	1.2e-43	150.4	C-terminal domain of Sin3a protein

cDNA / CDS / Protein 序列

下载基因组 DNA（仅基因区域）

每个公开基因均提供参考注释对应的转录本序列；蛋白编码基因另提供 CDS 和蛋白序列。非编码 RNA 不适用 CDS 或蛋白下载。真实 accession 的版本后缀予以保留。

cDNA

5 records

下载 cDNA FASTA

XM_057918763.1
ACTTCATATATAAACCAACCGCCACTGCATATATCCGACCTCTCTCTCTCCCTCTCAGAAACACACGCACAATAAAACTCGTGTTTTTCTCTCTCGGTTCAGGAGAGACGAAGAAAACACTCGGAAATATTTCTAATCAACATACAATATATTTGTATATACGTACATATACGCGTGCATACGTGCAAATTGTGCATACACACACTGCCACATTGTTTCGCACGAAGCTGGGATAAACTGTCTTCTGCTTCTTCATTGAT...

XM_057918762.1
ACTTCATATATAAACCAACCGCCACTGCATATATCCGACCTCTCTCTCTCCCTCTCAGAAACACACGCACAATAAAACTCGTGTTTTTCTCTCTCGGTTCAGGAGAGACGAAGAAAACACTCGGAAATATTTCTAATCAACATACAATATATTTGTATATACGTACATATACGCGTGCATACGTGCAAATTGTGCATACACACACTGCCACATTGTTTCGCACGAAGCTGGGATAAACTGTCTTCTGCTTCTTCATTGAT...

CDS

5 records

下载 CDS FASTA

LOC130993725
ATGAAGAGGTCTAGAGATGATGTGTTTGTAACTTCTCAAATTAAGCGGCCCGCCGTTTCACCTCGCGTCGAACAGTCTGGGCAAGTCCAATTATCAACTGCAAGCAGCGCCCAGAGGCTGACAATGACTGATGCCTTGTCATATCTCAAAAACATGAAGGAGATGTTCCAAGACAGAATGGATAAATATGGAGATTTTCTTGATGTCATGAAAGATTTTAAAGCTCAAAGAATTGATACATCCGGTGTCATATTGAGAGT...

Protein

5 records

下载 Protein FASTA

XP_057774745.1
MKRSRDDVFVTSQIKRPAVSPRVEQSGQVQLSTASSAQRLTMTDALSYLKNMKEMFQDRMDKYGDFLDVMKDFKAQRIDTSGVILRVKELFKGNRDLILGFNTFLPKGHEITLPLEDEPLLKKKPVEFDEAISFVTRIKTRFKGDDHVYRTFLDILNMCRKDNKSLTEVYKEVSLLFQGHPDLLVDFTHFLPDTSSAPSVHYAHSGRNHILLGDDRGSPMTLTRPTHVEKKPALCDGLVNHFDFEQFEKDKEKGEDGQKN...

XP_057774746.1
MKRSRDDVFVTSQIKRPAVSPRVEQSGQVQLSTASSAQRLTMTDALSYLKNMKEMFQDRMDKYGDFLDVMKDFKAQRIDTSGVILRVKELFKGNRDLILGFNTFLPKGHEITLPLEDEPLLKKKPVEFDEAISFVTRIKTRFKGDDHVYRTFLDILNMCRKDNKSLTEVYKEVSLLFQGHPDLLVDFTHFLPDTSSAPSVHYAHSGRNHILLGDDRGSPMTLTRPTHVEKFEKDKEKGEDGQKNEWEHDENLSHRRKSSL...

上下游序列下载

upstream/downstream 最大各 10000 bp。负链基因会自动反向互补，使最终 FASTA 为转录方向 5′→3′。

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