Gene Card 基因详情

支持统一新 ID、NCBI Gene ID、GeneID、locus_tag、Transcript ID、Protein ID，以及已人工核对的文献基因名查询。页面会先解析到丹参统一基因，再整合坐标、序列、注释、亚细胞定位、EMS 突变和下载入口。

当前解析结果

`SmilChr07G002864`

染色体: Chr07 坐标: 28797091-28801672 链方向: + 类型: protein_coding

基本信息

统一新 Gene ID	`SmilChr07G002864`
名称	SmilChr07G002864
描述	ERAD-associated E3 ubiquitin-protein ligase HRD1B-like
染色体 / SeqID	Chr07 / NC_080393.1
坐标与链方向	28797091 - 28801672 / `+`

ID 对照

NCBI Gene ID	`LOC130995862`
GeneID	`130995862`
locus_tag	`-`
NCBI Name	`LOC130995862`
原始查询	`SmilChr07G002864`

查看完整 ID 对照表

功能注释

来源	GFF basic annotation; KEGG smil; Pfam-A/HMMER; Arabidopsis/Rice homolog
描述	ERAD-associated E3 ubiquitin-protein ligase HRD1B-like
产物	ERAD-associated E3 ubiquitin-protein ligase HRD1B-like
Arabidopsis	`AT3G16090` (Hrd1A) RING/U-box superfamily protein [Source:NCBI gene (formerly Entrezgene);Acc:820854] identity=63; qcov=0.992; evalue=0; confidence=high
Rice	`Os06g0301000` (OsHrd1) - identity=62.4; qcov=0.956; evalue=0; confidence=high
GO	-
KEGG	smil04120 (Ubiquitin mediated proteolysis - Salvia miltiorrhiza (redroot sage)); smil04141 (Protein processing in endoplasmic reticulum - Salvia miltiorrhiza (redroot sage))
Pfam	PF00097 (zf-C3HC4); PF12678 (zf-rbx1); PF13445 (zf-RING_UBOX); PF13639 (zf-RING_2); PF13923 (zf-C3HC4_2); PF25563 (TPR_SYVN1_N)
InterPro	-
eggNOG	-
NR	GeneID:130995862

打开注释模块

亚细胞定位 Top 5

Rank	定位位置	中文	Score	Protein ID
1	Endoplasmic reticulum	内质网	1.00000	`XP_057777299.1`
2	Endoplasmic reticulum membrane	内质网膜	1.00000	`XP_057777299.1`
3	Nucleus	细胞核	0.20000	`XP_057777299.1`
4	Nucleus membrane	核膜	0.20000	`XP_057777299.1`
5	Chromosome	染色体	0.00000	`XP_057777299.1`

进入亚细胞定位查询

EMS 诱变突变

下表显示该基因在丹参 EMS 材料中的前 12 个候选突变；完整结果可进入 EMS 突变库继续筛选或下载。

位置	REF	ALT	类型	影响	携带材料数	材料
`Chr7:28798341`	`G`	`A`	EMS_canonical_SNV	CDS_variant	1	B99
`Chr7:28798351`	`C`	`T`	EMS_canonical_SNV	CDS_variant	1	D11
`Chr7:28798511`	`C`	`T`	EMS_canonical_SNV	CDS_variant	2	B136,D6
`Chr7:28798513`	`C`	`T`	EMS_canonical_SNV	CDS_variant	1	C46
`Chr7:28798715`	`C`	`T`	EMS_canonical_SNV	CDS_variant	2	B131,C2
`Chr7:28798754`	`C`	`T`	EMS_canonical_SNV	CDS_variant	2	B136,D6
`Chr7:28799386`	`G`	`A`	EMS_canonical_SNV	CDS_variant	2	C44,C71
`Chr7:28799956`	`C`	`T`	EMS_canonical_SNV	CDS_variant	3	B34,C38,C65
`Chr7:28800286`	`G`	`A`	EMS_canonical_SNV	CDS_variant	1	C71
`Chr7:28800333`	`C`	`T`	EMS_canonical_SNV	stop_gained	1	B49
`Chr7:28800333`	`C`	`T`	EMS_canonical_SNV	CDS_variant	1	B49
`Chr7:28800393`	`G`	`A`	EMS_canonical_SNV	CDS_variant	1	B125

进入 EMS 突变库

预测功能结构域

结构域结果来自 Pfam-A HMM 数据库和 HMMER hmmscan；位置为对应蛋白序列上的氨基酸坐标。

XP_057777299.1

526 aa

263

526

TPR_SYVN1_N

zf-rbx1

zf-RING_2

zf-RING_UBOX

zf-C3HC4

zf-C3HC4_2

PF25563 TPR_SYVN1_N 3-272 aa PF12678 zf-rbx1 290-330 aa PF13639 zf-RING_2 291-330 aa PF13445 zf-RING_UBOX 292-327 aa PF00097 zf-C3HC4 292-329 aa PF13923 zf-C3HC4_2 292-329 aa

XP_057777300.1

526 aa

263

526

TPR_SYVN1_N

zf-rbx1

zf-RING_2

zf-RING_UBOX

zf-C3HC4

zf-C3HC4_2

PF25563 TPR_SYVN1_N 3-272 aa PF12678 zf-rbx1 290-330 aa PF13639 zf-RING_2 291-330 aa PF13445 zf-RING_UBOX 292-327 aa PF00097 zf-C3HC4 292-329 aa PF13923 zf-C3HC4_2 292-329 aa

XP_057777302.1

526 aa

263

526

TPR_SYVN1_N

zf-rbx1

zf-RING_2

zf-RING_UBOX

zf-C3HC4

zf-C3HC4_2

PF25563 TPR_SYVN1_N 3-272 aa PF12678 zf-rbx1 290-330 aa PF13639 zf-RING_2 291-330 aa PF13445 zf-RING_UBOX 292-327 aa PF00097 zf-C3HC4 292-329 aa PF13923 zf-C3HC4_2 292-329 aa

XP_057777303.1

526 aa

263

526

TPR_SYVN1_N

zf-rbx1

zf-RING_2

zf-RING_UBOX

zf-C3HC4

zf-C3HC4_2

PF25563 TPR_SYVN1_N 3-272 aa PF12678 zf-rbx1 290-330 aa PF13639 zf-RING_2 291-330 aa PF13445 zf-RING_UBOX 292-327 aa PF00097 zf-C3HC4 292-329 aa PF13923 zf-C3HC4_2 292-329 aa

Protein ID	来源	结构域编号	结构域名称	类型	起始 aa	终止 aa	E-value	Score	说明
`XP_057777299.1`	Pfam	`PF25563`	TPR_SYVN1_N	Repeat	3	272	5.3e-106	354.7	E3 ubiquitin-protein ligase synoviolin-like, TPR repeats
`XP_057777299.1`	Pfam	`PF12678`	zf-rbx1	Domain	290	330	2.1e-08	35.0	RING-H2 zinc finger domain
`XP_057777299.1`	Pfam	`PF13639`	zf-RING_2	Domain	291	330	1.4e-11	45.1	Ring finger domain
`XP_057777299.1`	Pfam	`PF13445`	zf-RING_UBOX	Domain	292	327	2.5e-06	28.1	RING-type zinc-finger
`XP_057777299.1`	Pfam	`PF00097`	zf-C3HC4	Domain	292	329	8.2e-09	35.9	Zinc finger, C3HC4 type (RING finger)
`XP_057777299.1`	Pfam	`PF13923`	zf-C3HC4_2	Domain	292	329	5.6e-07	30.0	Zinc finger, C3HC4 type (RING finger)
`XP_057777300.1`	Pfam	`PF25563`	TPR_SYVN1_N	Repeat	3	272	5.3e-106	354.7	E3 ubiquitin-protein ligase synoviolin-like, TPR repeats
`XP_057777300.1`	Pfam	`PF12678`	zf-rbx1	Domain	290	330	2.1e-08	35.0	RING-H2 zinc finger domain
`XP_057777300.1`	Pfam	`PF13639`	zf-RING_2	Domain	291	330	1.4e-11	45.1	Ring finger domain
`XP_057777300.1`	Pfam	`PF13445`	zf-RING_UBOX	Domain	292	327	2.5e-06	28.1	RING-type zinc-finger
`XP_057777300.1`	Pfam	`PF00097`	zf-C3HC4	Domain	292	329	8.2e-09	35.9	Zinc finger, C3HC4 type (RING finger)
`XP_057777300.1`	Pfam	`PF13923`	zf-C3HC4_2	Domain	292	329	5.6e-07	30.0	Zinc finger, C3HC4 type (RING finger)
`XP_057777302.1`	Pfam	`PF25563`	TPR_SYVN1_N	Repeat	3	272	5.3e-106	354.7	E3 ubiquitin-protein ligase synoviolin-like, TPR repeats
`XP_057777302.1`	Pfam	`PF12678`	zf-rbx1	Domain	290	330	2.1e-08	35.0	RING-H2 zinc finger domain
`XP_057777302.1`	Pfam	`PF13639`	zf-RING_2	Domain	291	330	1.4e-11	45.1	Ring finger domain
`XP_057777302.1`	Pfam	`PF13445`	zf-RING_UBOX	Domain	292	327	2.5e-06	28.1	RING-type zinc-finger
`XP_057777302.1`	Pfam	`PF00097`	zf-C3HC4	Domain	292	329	8.2e-09	35.9	Zinc finger, C3HC4 type (RING finger)
`XP_057777302.1`	Pfam	`PF13923`	zf-C3HC4_2	Domain	292	329	5.6e-07	30.0	Zinc finger, C3HC4 type (RING finger)
`XP_057777303.1`	Pfam	`PF25563`	TPR_SYVN1_N	Repeat	3	272	5.3e-106	354.7	E3 ubiquitin-protein ligase synoviolin-like, TPR repeats
`XP_057777303.1`	Pfam	`PF12678`	zf-rbx1	Domain	290	330	2.1e-08	35.0	RING-H2 zinc finger domain
`XP_057777303.1`	Pfam	`PF13639`	zf-RING_2	Domain	291	330	1.4e-11	45.1	Ring finger domain
`XP_057777303.1`	Pfam	`PF13445`	zf-RING_UBOX	Domain	292	327	2.5e-06	28.1	RING-type zinc-finger
`XP_057777303.1`	Pfam	`PF00097`	zf-C3HC4	Domain	292	329	8.2e-09	35.9	Zinc finger, C3HC4 type (RING finger)
`XP_057777303.1`	Pfam	`PF13923`	zf-C3HC4_2	Domain	292	329	5.6e-07	30.0	Zinc finger, C3HC4 type (RING finger)

cDNA / CDS / Protein 序列

下载基因组 DNA（仅基因区域）

每个公开基因均提供参考注释对应的转录本序列；蛋白编码基因另提供 CDS 和蛋白序列。非编码 RNA 不适用 CDS 或蛋白下载。真实 accession 的版本后缀予以保留。

cDNA

4 records

下载 cDNA FASTA

XM_057921320.1
GTTGACATGGCAGACCAAATTGTAGCGAATGGAAACGTGACACGTCATATATTACACCTCACCTTAATTGCCTCCCAACCCCCGCGAAACCGGGCGAATGATCCTTCCGCTTTAAATTTCCCGTAAATTTCAACATAATCCTTTTTTCTGAGGAGTAAATTTCAACATAATCAATTTTTCTGTAAATTTGGGATTTCTTCTTCAAAATATTTGGCTATTGATTTGGTATTTTGGATGAATAGAGGCTAACTGAAATGATG...

XM_057921317.1
TATATTACACCTCACCTTAATTGCCTCCCAACCCCCGCGAAACCGGGCGAATGATCCTTCCGCTTTAAATTTCCCGTAAATTTCAACATAATCCTTTTTTCTGAGGAGTAAATTTCAACATAATCAATTTTTCTGTAAATTTGGGATTTCTTCTTCAAAATATTTGGCTATTGATTTGGTATTTTGGATGAATAGAGGCTAACTGAAATGATGAAGTTGCAAACTTACGCTGGGTTCAGTTTGATAGCTGCATTGGCTAT...

CDS

4 records

下载 CDS FASTA

LOC130995862
ATGATGAAGTTGCAAACTTACGCTGGGTTCAGTTTGATAGCTGCATTGGCTATTATTTATCATGCCTTTGATAGTAGAGGCCAATTTTACCCTGCAATGGTTTATTTGTCGACCTCAAAGATCAGTCTAGTGCTTCTTCTGAATATGGGTTTGGTTTTTATGTGCATCCTGTGGCAATTGACCAAGAAAATCTTCCTTGGTTCGCTCCGAGAAGCAGAGGTCGAGAGGCTGAATGAGCAGTCATGGCGGGAGGTCATGGA...

Protein

4 records

下载 Protein FASTA

XP_057777299.1
MMKLQTYAGFSLIAALAIIYHAFDSRGQFYPAMVYLSTSKISLVLLLNMGLVFMCILWQLTKKIFLGSLREAEVERLNEQSWREVMEILFAITIFRQDFSVTFLAMVTALLLIKSLHWLAQKRVEYIETTPTVPKLSHVRIVSFMVFLLLIDSIFLYDSVEHLIETRQASVALFFSFEYIILATTTLSTFVKYMFHVSDMLMEGQWEKKAVCTFYLELIRDLLHLTLCMCFFLVIFLNYGVPLHLIRELYETFRNFRIRV...

XP_057777300.1
MMKLQTYAGFSLIAALAIIYHAFDSRGQFYPAMVYLSTSKISLVLLLNMGLVFMCILWQLTKKIFLGSLREAEVERLNEQSWREVMEILFAITIFRQDFSVTFLAMVTALLLIKSLHWLAQKRVEYIETTPTVPKLSHVRIVSFMVFLLLIDSIFLYDSVEHLIETRQASVALFFSFEYIILATTTLSTFVKYMFHVSDMLMEGQWEKKAVCTFYLELIRDLLHLTLCMCFFLVIFLNYGVPLHLIRELYETFRNFRIRV...

上下游序列下载

upstream/downstream 最大各 10000 bp。负链基因会自动反向互补，使最终 FASTA 为转录方向 5′→3′。

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