Gene Card 基因详情

支持统一新 ID、NCBI Gene ID、GeneID、locus_tag、Transcript ID、Protein ID，以及已人工核对的文献基因名查询。页面会先解析到丹参统一基因，再整合坐标、序列、注释、亚细胞定位、EMS 突变和下载入口。

当前解析结果

`SmilChr07G004184`

染色体: Chr07 坐标: 53820587-53828179 链方向: + 类型: protein_coding

基本信息

统一新 Gene ID	`SmilChr07G004184`
名称	SmilChr07G004184
描述	general transcription and DNA repair factor IIH helicase subunit XPB1
染色体 / SeqID	Chr07 / NC_080393.1
坐标与链方向	53820587 - 53828179 / `+`

ID 对照

NCBI Gene ID	`LOC130994818`
GeneID	`130994818`
locus_tag	`-`
NCBI Name	`LOC130994818`
原始查询	`SmilChr07G004184`

查看完整 ID 对照表

功能注释

来源	GFF basic annotation; NCBI GO GAF; KEGG smil; Pfam-A/HMMER; Arabidopsis/Rice homolog
描述	general transcription and DNA repair factor IIH helicase subunit XPB1
产物	general transcription and DNA repair factor IIH helicase subunit XPB1
Arabidopsis	`AT5G41370` (XPB1) DNA repair helicase XPB1-like protein [Source:NCBI gene (formerly Entrezgene);Acc:834139] identity=85.5; qcov=1; evalue=0; confidence=high
Rice	`Os01g0691600` (OsXPB2) - identity=83.8; qcov=0.753; evalue=0; confidence=high
GO	GO:0000112 (nucleotide-excision repair factor 3 complex); GO:0003677 (DNA binding); GO:0005524 (ATP binding); GO:0005675 (transcription factor TFIIH holo complex); GO:0006289 (nucleotide-excision repair); GO:0006367 (transcription initiation at RNA polymerase II promoter); GO:0016787 (hydrolase activity); GO:0043138 (3'-5' DNA helicase activity); GO:0097550 (transcription preinitiation complex)
KEGG	smil03022 (Basal transcription factors - Salvia miltiorrhiza (redroot sage)); smil03420 (Nucleotide excision repair - Salvia miltiorrhiza (redroot sage))
Pfam	PF00271 (Helicase_C); PF04851 (ResIII); PF13625 (Helicase_C_3); PF16203 (ERCC3_RAD25_C)
InterPro	-
eggNOG	-
NR	GeneID:130994818

打开注释模块

亚细胞定位 Top 5

Rank	定位位置	中文	Score	Protein ID
1	Nucleus	细胞核	1.00000	`XP_057775871.1`
2	Nucleolus	核仁	0.60000	`XP_057775871.1`
3	Nucleoplasm	核质	0.60000	`XP_057775871.1`
4	Chromosome	染色体	0.40000	`XP_057775871.1`
5	Nucleolar fibrillar center	Nucleolar fibrillar center	0.40000	`XP_057775871.1`

进入亚细胞定位查询

EMS 诱变突变

下表显示该基因在丹参 EMS 材料中的前 12 个候选突变；完整结果可进入 EMS 突变库继续筛选或下载。

位置	REF	ALT	类型	影响	携带材料数	材料
`Chr7:53820840`	`G`	`A`	EMS_canonical_SNV	CDS_variant	2	B109,C36
`Chr7:53820842`	`C`	`CG`	1bp_insertion	frameshift_variant	2	B109,C36
`Chr7:53820842`	`C`	`CG`	1bp_insertion	CDS_variant	2	B109,C36
`Chr7:53820843`	`C`	`T`	EMS_canonical_SNV	CDS_variant	3	C47,C73,C86
`Chr7:53820856`	`CAA`	`C`	2bp_deletion	frameshift_variant	2	B109,C36
`Chr7:53820856`	`CAA`	`C`	2bp_deletion	CDS_variant	2	B109,C36
`Chr7:53821261`	`G`	`A`	EMS_canonical_SNV	CDS_variant	1	B136
`Chr7:53821839`	`C`	`T`	EMS_canonical_SNV	CDS_variant	2	B12,B55
`Chr7:53821881`	`G`	`A`	EMS_canonical_SNV	CDS_variant	2	B12,B55
`Chr7:53822034`	`C`	`T`	EMS_canonical_SNV	CDS_variant	2	B132,C6
`Chr7:53822143`	`C`	`T`	EMS_canonical_SNV	CDS_variant	2	B12,B55
`Chr7:53822144`	`G`	`A`	EMS_canonical_SNV	CDS_variant	2	B82,C31

进入 EMS 突变库

预测功能结构域

结构域结果来自 Pfam-A HMM 数据库和 HMMER hmmscan；位置为对应蛋白序列上的氨基酸坐标。

XP_057775871.1

765 aa

382

765

Helicase_C_3

ResIII

ERCC3_RAD25_C

Helicase_C

PF13625 Helicase_C_3 64-187 aa PF04851 ResIII 279-436 aa PF16203 ERCC3_RAD25_C 461-707 aa PF00271 Helicase_C 511-613 aa

XP_057775872.1

765 aa

382

765

Helicase_C_3

ResIII

ERCC3_RAD25_C

Helicase_C

PF13625 Helicase_C_3 64-187 aa PF04851 ResIII 279-436 aa PF16203 ERCC3_RAD25_C 461-707 aa PF00271 Helicase_C 511-613 aa

Protein ID	来源	结构域编号	结构域名称	类型	起始 aa	终止 aa	E-value	Score	说明
`XP_057775871.1`	Pfam	`PF13625`	Helicase_C_3	Domain	64	187	1.4e-33	116.3	Helicase conserved C-terminal domain
`XP_057775871.1`	Pfam	`PF04851`	ResIII	Family	279	436	3.3e-18	66.8	Type III restriction enzyme, res subunit
`XP_057775871.1`	Pfam	`PF16203`	ERCC3_RAD25_C	Domain	461	707	1.2e-116	389.1	ERCC3/RAD25/XPB C-terminal helicase
`XP_057775871.1`	Pfam	`PF00271`	Helicase_C	Domain	511	613	1.5e-13	51.6	Helicase conserved C-terminal domain
`XP_057775872.1`	Pfam	`PF13625`	Helicase_C_3	Domain	64	187	1.4e-33	116.3	Helicase conserved C-terminal domain
`XP_057775872.1`	Pfam	`PF04851`	ResIII	Family	279	436	3.3e-18	66.8	Type III restriction enzyme, res subunit
`XP_057775872.1`	Pfam	`PF16203`	ERCC3_RAD25_C	Domain	461	707	1.2e-116	389.1	ERCC3/RAD25/XPB C-terminal helicase
`XP_057775872.1`	Pfam	`PF00271`	Helicase_C	Domain	511	613	1.5e-13	51.6	Helicase conserved C-terminal domain

cDNA / CDS / Protein 序列

下载基因组 DNA（仅基因区域）

每个公开基因均提供参考注释对应的转录本序列；蛋白编码基因另提供 CDS 和蛋白序列。非编码 RNA 不适用 CDS 或蛋白下载。真实 accession 的版本后缀予以保留。

cDNA

2 records

下载 cDNA FASTA

XM_057919889.1
CGCCGCCTCGCCCCCGCCTTATATTAAAACACACAACACATAATTTTCGCTAAGTTAGCTACGAAGGAAGTTTGTGGAATCCACACAATGGGAAACGGTGACAAAAATCGGCCCAGCAAAAGGATCAAGTTCTCAAAGGATGAACATAGGGCTTCGACTGCAGAAGACTATAGTTCTCACTTCGGAGAAGATTTGGAGGATGATCCTCGTGATGGTGAGGGGAAAAAGAGGGATTTCTCGAAATTGGAACTCAAACCTGA...

XM_057919888.1
CACATAATTTTCGCTAAGTTAGCTACGAAGGAAGTTTGTGGAATCCACACAATGGGAAACGGTGACAAAAATCGGCCCAGCAAAAGGATCAAGTTCTCAAAGGATGAACATAGGGCTTCGACTGCAGAAGACTATAGTTCTCACTTCGGAGAAGATTTGGAGGATGATCCTCGTGATGGTGAGGGGAAAAAGAGGGATTTCTCGAAATTGGAACTCAAACCTGATCACATGAATCGGCCCTTATGGGCTTGTGCCGATGG...

CDS

2 records

下载 CDS FASTA

LOC130994818
ATGGGAAACGGTGACAAAAATCGGCCCAGCAAAAGGATCAAGTTCTCAAAGGATGAACATAGGGCTTCGACTGCAGAAGACTATAGTTCTCACTTCGGAGAAGATTTGGAGGATGATCCTCGTGATGGTGAGGGGAAAAAGAGGGATTTCTCGAAATTGGAACTCAAACCTGATCACATGAATCGGCCCTTATGGGCTTGTGCCGATGGTCGGATTTTCCTTGAAACTTTCTCCTCATTATACAAACAGGCGTATGATTT...

Protein

2 records

下载 Protein FASTA

XP_057775871.1
MGNGDKNRPSKRIKFSKDEHRASTAEDYSSHFGEDLEDDPRDGEGKKRDFSKLELKPDHMNRPLWACADGRIFLETFSSLYKQAYDFLIAIAEPVCRPESMHEYNLTPHSLYAAVSVGLETETIISVLNKLSKTKLPKEMIDFIHNSTANYGKVKLVLKKNKYFVESPFPEVLKTLLKDDVIGRARISSEGSRGADGFTVGKSAGEIEGTHEELLNEAELAAAAEEKETHAFEIDPTQVENVKQRCLPNALNYPMLEEYD...

XP_057775872.1
MGNGDKNRPSKRIKFSKDEHRASTAEDYSSHFGEDLEDDPRDGEGKKRDFSKLELKPDHMNRPLWACADGRIFLETFSSLYKQAYDFLIAIAEPVCRPESMHEYNLTPHSLYAAVSVGLETETIISVLNKLSKTKLPKEMIDFIHNSTANYGKVKLVLKKNKYFVESPFPEVLKTLLKDDVIGRARISSEGSRGADGFTVGKSAGEIEGTHEELLNEAELAAAAEEKETHAFEIDPTQVENVKQRCLPNALNYPMLEEYD...

上下游序列下载

upstream/downstream 最大各 10000 bp。负链基因会自动反向互补，使最终 FASTA 为转录方向 5′→3′。

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