Gene Card 基因详情

支持统一新 ID、NCBI Gene ID、GeneID、locus_tag、Transcript ID、Protein ID，以及已人工核对的文献基因名查询。页面会先解析到丹参统一基因，再整合坐标、序列、注释、亚细胞定位、EMS 突变和下载入口。

当前解析结果

`SmilChr08G000218`

染色体: Chr08 坐标: 1485566-1491782 链方向: + 类型: protein_coding

基本信息

统一新 Gene ID	`SmilChr08G000218`
名称	SmilChr08G000218
描述	pre-mRNA-processing factor 19 homolog 1-like
染色体 / SeqID	Chr08 / NC_080394.1
坐标与链方向	1485566 - 1491782 / `+`

ID 对照

NCBI Gene ID	`LOC130999824`
GeneID	`130999824`
locus_tag	`-`
NCBI Name	`LOC130999824`
原始查询	`SmilChr08G000218`

查看完整 ID 对照表

功能注释

来源	GFF basic annotation; NCBI GO GAF; KEGG smil; Pfam-A/HMMER; Arabidopsis/Rice homolog
描述	pre-mRNA-processing factor 19 homolog 1-like
产物	pre-mRNA-processing factor 19 homolog 1-like
Arabidopsis	`AT1G04510` (MAC3A) MOS4-associated complex 3A [Source:NCBI gene (formerly Entrezgene);Acc:839503] identity=72.2; qcov=0.998; evalue=0; confidence=high
Rice	`Os10g0466300` (OsWD40-178) - identity=73.5; qcov=0.991; evalue=0; confidence=high
GO	GO:0000398 (mRNA splicing, via spliceosome); GO:0000974 (Prp19 complex); GO:0005515 (protein binding); GO:0005737 (cytoplasm); GO:0006281 (DNA repair); GO:0016567 (protein ubiquitination); GO:0061630 (ubiquitin protein ligase activity); GO:0071006 (U2-type catalytic step 1 spliceosome)
KEGG	smil03040 (Spliceosome - Salvia miltiorrhiza (redroot sage)); smil04120 (Ubiquitin mediated proteolysis - Salvia miltiorrhiza (redroot sage))
Pfam	PF00400 (WD40); PF08606 (Prp19); PF12894 (ANAPC4_WD40); PF23098 (Beta-prop_NOL10_N); PF23381 (Beta-prop_IFT122_1st); PF24814 (WD40_Prp19)
InterPro	-
eggNOG	-
NR	GeneID:130999824

打开注释模块

亚细胞定位 Top 5

Rank	定位位置	中文	Score	Protein ID
1	Nucleus	细胞核	1.00000	`XP_057781469.1`
2	Nucleoplasm	核质	0.60000	`XP_057781469.1`
3	Cytoplasm	细胞质	0.60000	`XP_057781469.1`
4	Chromosome	染色体	0.20000	`XP_057781469.1`
5	Centromere	着丝粒	0.00000	`XP_057781469.1`

进入亚细胞定位查询

EMS 诱变突变

下表显示该基因在丹参 EMS 材料中的前 12 个候选突变；完整结果可进入 EMS 突变库继续筛选或下载。

位置	REF	ALT	类型	影响	携带材料数	材料
`Chr8:1485859`	`C`	`T`	EMS_canonical_SNV	CDS_variant	2	B1,B7
`Chr8:1485871`	`G`	`A`	EMS_canonical_SNV	CDS_variant	1	B140
`Chr8:1486696`	`G`	`A`	EMS_canonical_SNV	CDS_variant	5	A18,B135,B35,C19,C58
`Chr8:1487459`	`G`	`A`	EMS_canonical_SNV	CDS_variant	3	B130,C11,C69
`Chr8:1487510`	`G`	`A`	EMS_canonical_SNV	CDS_variant	1	D6
`Chr8:1487735`	`C`	`T`	EMS_canonical_SNV	CDS_variant	4	B134,B3,B63,C79
`Chr8:1487848`	`C`	`T`	EMS_canonical_SNV	CDS_variant	1	B85
`Chr8:1487881`	`G`	`A`	EMS_canonical_SNV	CDS_variant	3	B125,B132,C31
`Chr8:1487924`	`G`	`A`	EMS_canonical_SNV	CDS_variant	1	C21
`Chr8:1487936`	`G`	`A`	EMS_canonical_SNV	CDS_variant	5	A8,B120,B131,C46,D11
`Chr8:1488140`	`G`	`A`	EMS_canonical_SNV	CDS_variant	3	B140,B20,C31
`Chr8:1489100`	`C`	`T`	EMS_canonical_SNV	CDS_variant	5	A5,B34,B46,B50,B55

进入 EMS 突变库

预测功能结构域

结构域结果来自 Pfam-A HMM 数据库和 HMMER hmmscan；位置为对应蛋白序列上的氨基酸坐标。

XP_057781469.1

529 aa

264

529

Prp19

WD40_Prp19

ANAPC4_WD40

Beta-prop_IFT122_1st

WD40

Beta-prop_NOL10_N

WD40

PF08606 Prp19 66-131 aa PF24814 WD40_Prp19 219-511 aa PF12894 ANAPC4_WD40 235-297 aa PF23381 Beta-prop_IFT122_1st 236-516 aa PF00400 WD40 256-293 aa PF00400 WD40 302-338 aa PF23098 Beta-prop_NOL10_N 325-502 aa PF00400 WD40 357-384 aa PF00400 WD40 390-428 aa PF00400 WD40 479-517 aa

XP_057781470.1

529 aa

264

529

Prp19

WD40_Prp19

ANAPC4_WD40

Beta-prop_IFT122_1st

WD40

Beta-prop_NOL10_N

WD40

Protein ID	来源	结构域编号	结构域名称	类型	起始 aa	终止 aa	E-value	Score	说明
`XP_057781469.1`	Pfam	`PF08606`	Prp19	Domain	66	131	1.9e-29	102.1	Prp19/Pso4-like
`XP_057781469.1`	Pfam	`PF24814`	WD40_Prp19	Repeat	219	511	6.6e-106	354.2	Prp19 WD40 domain
`XP_057781469.1`	Pfam	`PF12894`	ANAPC4_WD40	Repeat	235	297	8.1e-14	52.4	Anaphase-promoting complex subunit 4 WD40 domain
`XP_057781469.1`	Pfam	`PF23381`	Beta-prop_IFT122_1st	Repeat	236	516	1.9e-40	139.7	IFT122 first beta-propeller
`XP_057781469.1`	Pfam	`PF00400`	WD40	Repeat	256	293	5e-39	131.8	WD domain, G-beta repeat
`XP_057781469.1`	Pfam	`PF00400`	WD40	Repeat	302	338	5e-39	131.8	WD domain, G-beta repeat
`XP_057781469.1`	Pfam	`PF23098`	Beta-prop_NOL10_N	Repeat	325	502	2.9e-11	43.9	Nucleolar protein 10-like, N-terminal domain
`XP_057781469.1`	Pfam	`PF00400`	WD40	Repeat	357	384	5e-39	131.8	WD domain, G-beta repeat
`XP_057781469.1`	Pfam	`PF00400`	WD40	Repeat	390	428	5e-39	131.8	WD domain, G-beta repeat
`XP_057781469.1`	Pfam	`PF00400`	WD40	Repeat	479	517	5e-39	131.8	WD domain, G-beta repeat
`XP_057781470.1`	Pfam	`PF08606`	Prp19	Domain	66	131	1.9e-29	102.1	Prp19/Pso4-like
`XP_057781470.1`	Pfam	`PF24814`	WD40_Prp19	Repeat	219	511	6.6e-106	354.2	Prp19 WD40 domain
`XP_057781470.1`	Pfam	`PF12894`	ANAPC4_WD40	Repeat	235	297	8.1e-14	52.4	Anaphase-promoting complex subunit 4 WD40 domain
`XP_057781470.1`	Pfam	`PF23381`	Beta-prop_IFT122_1st	Repeat	236	516	1.9e-40	139.7	IFT122 first beta-propeller
`XP_057781470.1`	Pfam	`PF00400`	WD40	Repeat	256	293	5e-39	131.8	WD domain, G-beta repeat
`XP_057781470.1`	Pfam	`PF00400`	WD40	Repeat	302	338	5e-39	131.8	WD domain, G-beta repeat
`XP_057781470.1`	Pfam	`PF23098`	Beta-prop_NOL10_N	Repeat	325	502	2.9e-11	43.9	Nucleolar protein 10-like, N-terminal domain
`XP_057781470.1`	Pfam	`PF00400`	WD40	Repeat	357	384	5e-39	131.8	WD domain, G-beta repeat
`XP_057781470.1`	Pfam	`PF00400`	WD40	Repeat	390	428	5e-39	131.8	WD domain, G-beta repeat
`XP_057781470.1`	Pfam	`PF00400`	WD40	Repeat	479	517	5e-39	131.8	WD domain, G-beta repeat

cDNA / CDS / Protein 序列

下载基因组 DNA（仅基因区域）

每个公开基因均提供参考注释对应的转录本序列；蛋白编码基因另提供 CDS 和蛋白序列。非编码 RNA 不适用 CDS 或蛋白下载。真实 accession 的版本后缀予以保留。

cDNA

2 records

下载 cDNA FASTA

XM_057925486.1
GCAATTTCGCGACTCCAAATTTATACAACTTTGAATCGACGATTTTGTGGTATTTGCCTTCTCACCCTCCCTCACTGTATCCCTCTTGCTAGACCATAAACCCTAGCGCATATACAGAGCAAAGCAGCAAACGCCATGAATTGTTCAATTTCTGGCGAGGTGCCGGAGGAGCCTGTGGTCTCGAAGAGTTCCGGTCTCCTCTTCGAGAAGCGCTTAATCGAGCGTCACATCTCGGACTTTGGTAAATGTCCCATTACTGG...

XM_057925487.1
TCGCGACTCCAAATTTATACAACTTTGAATCGACGATTTTGTGGTATTTGCCTTCTCACCCTCCCTCACTGTATCCCTCTTGCTAGACCATAAACCCTAGCGCATATACAGAGCAAAGCAGCAAACGCCATGAATTGTTCAATTTCTGGCGAGGTGCCGGAGGAGCCTGTGGTCTCGAAGAGTTCCGGTCTCCTCTTCGAGAAGCGCTTAATCGAGCGTCACATCTCGGACTTTGGTAAATGTCCCATTACTGGAGAGCC...

CDS

2 records

下载 CDS FASTA

LOC130999824
ATGAATTGTTCAATTTCTGGCGAGGTGCCGGAGGAGCCTGTGGTCTCGAAGAGTTCCGGTCTCCTCTTCGAGAAGCGCTTAATCGAGCGTCACATCTCGGACTTTGGTAAATGTCCCATTACTGGAGAGCCTATGACAATGGATGATATTGTTCCTGTCAAGGCTGGGAAGATTGTGAAGCCCCGACCAATGCAGACTGCTAGTATCCCTGGGATGCTGGGAATGTTTCAGATAGAATGGGATGGTTTGATGCTATCAAA...

Protein

2 records

下载 Protein FASTA

XP_057781469.1
MNCSISGEVPEEPVVSKSSGLLFEKRLIERHISDFGKCPITGEPMTMDDIVPVKAGKIVKPRPMQTASIPGMLGMFQIEWDGLMLSNFALEQQLHTARQELSHALYQHDAACRVIARLKKERDEARELLAQAERQIPMSVAAQDTVNAAALSNGKRAIEDGEMGPDGKRVRLGISNSIISELTDCNAVLSQQRKKRQIPSTLAPIEAVERYTQLTVNPLHKTSKPGILSMDILYSKDLIATAGADSNAVVFDRSSGQVVS...

XP_057781470.1
MNCSISGEVPEEPVVSKSSGLLFEKRLIERHISDFGKCPITGEPMTMDDIVPVKAGKIVKPRPMQTASIPGMLGMFQIEWDGLMLSNFALEQQLHTARQELSHALYQHDAACRVIARLKKERDEARELLAQAERQIPMSVAAQDTVNAAALSNGKRAIEDGEMGPDGKRVRLGISNSIISELTDCNAVLSQQRKKRQIPSTLAPIEAVERYTQLTVNPLHKTSKPGILSMDILYSKDLIATAGADSNAVVFDRSSGQVVS...

上下游序列下载

upstream/downstream 最大各 10000 bp。负链基因会自动反向互补，使最终 FASTA 为转录方向 5′→3′。

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