Gene Card 基因详情

支持统一新 ID、NCBI Gene ID、GeneID、locus_tag、Transcript ID、Protein ID，以及已人工核对的文献基因名查询。页面会先解析到丹参统一基因，再整合坐标、序列、注释、亚细胞定位、EMS 突变和下载入口。

当前解析结果

`SmilChr08G000401`

染色体: Chr08 坐标: 2814778-2819120 链方向: - 类型: protein_coding

基本信息

统一新 Gene ID	`SmilChr08G000401`
名称	SmilChr08G000401
描述	disease resistance protein RGA2-like
染色体 / SeqID	Chr08 / NC_080394.1
坐标与链方向	2814778 - 2819120 / `-`

ID 对照

NCBI Gene ID	`LOC130999989`
GeneID	`130999989`
locus_tag	`-`
NCBI Name	`LOC130999989`
原始查询	`SmilChr08G000401`

查看完整 ID 对照表

功能注释

来源	GFF basic annotation; NCBI GO GAF; Pfam-A/HMMER; Arabidopsis/Rice homolog
描述	disease resistance protein RGA2-like
产物	disease resistance protein RGA2-like
Arabidopsis	`AT3G14470` (AT3G14470) NB-ARC domain-containing disease resistance protein [Source:NCBI gene (formerly Entrezgene);Acc:820670] identity=31.5; qcov=0.899; evalue=7.55e-118; confidence=low
Rice	`Os05g0492200` (YR1) - identity=32.8; qcov=1.04; evalue=7.38e-145; confidence=low
GO	GO:0043531 (ADP binding); GO:0098542 (defense response to other organism)
KEGG	-
Pfam	PF00931 (NB-ARC); PF18052 (Rx_N); PF23247 (LRR_RPS2); PF23559 (WHD_DRP); PF23598 (LRR_14); PF25019 (LRR_R13L1-DRL21)
InterPro	-
eggNOG	-
NR	GeneID:130999989

打开注释模块

亚细胞定位 Top 5

Rank	定位位置	中文	Score	Protein ID
1	Cell membrane	细胞膜	0.80000	`XP_057781685.1`
2	Cytosol	细胞质基质	0.40000	`XP_057781685.1`
3	Nucleus	细胞核	0.00000	`XP_057781685.1`
4	Chromosome	染色体	0.00000	`XP_057781685.1`
5	Centromere	着丝粒	0.00000	`XP_057781685.1`

进入亚细胞定位查询

EMS 诱变突变

下表显示该基因在丹参 EMS 材料中的前 12 个候选突变；完整结果可进入 EMS 突变库继续筛选或下载。

位置	REF	ALT	类型	影响	携带材料数	材料
`Chr8:2815459`	`A`	`ATG`	2bp_insertion	frameshift_variant	57	A1,A15,A2,B1,B10,B100,B106,B110,B114,B125,B131,B136,B139,B14,B140,B2,B21,B23,B24,B26,B27,B29,B3,B31,B32,B34,B41,B45,B47,B48,B55,B62,B66,B72,B8,B84,C1,C14,C21,C24,C3,C31,C35,C36,C37,C38,C41,C48,C57,C63,C67,C79,C82,C83,C86,D10,D2
`Chr8:2815506`	`C`	`T`	EMS_canonical_SNV	CDS_variant	2	A9,D2
`Chr8:2815508`	`G`	`A`	EMS_canonical_SNV	CDS_variant	5	B36,B80,B81,C47,D8
`Chr8:2815535`	`G`	`A`	EMS_canonical_SNV	CDS_variant	4	C26,C43,C58,C84
`Chr8:2815537`	`G`	`A`	EMS_canonical_SNV	CDS_variant	3	A11,A13,C47
`Chr8:2815540`	`ATC`	`A`	2bp_deletion	frameshift_variant	43	A5,B104,B11,B112,B117,B125,B126,B133,B135,B138,B140,B25,B38,B48,B49,B5,B52,B56,B60,B7,B71,B78,B91,B95,C11,C15,C23,C31,C32,C36,C39,C4,C43,C46,C48,C52,C56,C69,C7,C71,C73,C8,D9
`Chr8:2815553`	`A`	`ACT`	2bp_insertion	frameshift_variant	9	A18,B124,B128,B132,B134,B31,B64,B65,C30
`Chr8:2815554`	`GT`	`G`	1bp_deletion	frameshift_variant	3	B113,B54,B86
`Chr8:2815554`	`GT`	`G`	1bp_deletion	CDS_variant	3	B113,B54,B86
`Chr8:2815568`	`G`	`A`	EMS_canonical_SNV	CDS_variant	1	C48
`Chr8:2815573`	`G`	`A`	EMS_canonical_SNV	CDS_variant	1	B107
`Chr8:2815574`	`C`	`T`	EMS_canonical_SNV	CDS_variant	2	B53,C65

进入 EMS 突变库

预测功能结构域

结构域结果来自 Pfam-A HMM 数据库和 HMMER hmmscan；位置为对应蛋白序列上的氨基酸坐标。

XP_057781685.1

1126 aa

563

1126

Rx_N

NB-ARC

WHD_DRP

LRR_14

LRR_R13L1-DRL21

LRR_RPS2

PF18052 Rx_N 10-97 aa PF00931 NB-ARC 171-340 aa PF23559 WHD_DRP 424-495 aa PF23598 LRR_14 533-816 aa PF25019 LRR_R13L1-DRL21 660-784 aa PF23247 LRR_RPS2 750-867 aa

Protein ID	来源	结构域编号	结构域名称	类型	起始 aa	终止 aa	E-value	Score	说明
`XP_057781685.1`	Pfam	`PF18052`	Rx_N	Domain	10	97	1.1e-20	74.3	Rx N-terminal domain
`XP_057781685.1`	Pfam	`PF00931`	NB-ARC	Domain	171	340	2.7e-34	119.0	NB-ARC domain
`XP_057781685.1`	Pfam	`PF23559`	WHD_DRP	Domain	424	495	2.3e-25	89.1	Disease resistance protein Winged helix domain
`XP_057781685.1`	Pfam	`PF23598`	LRR_14	Repeat	533	816	1.2e-47	163.1	Leucine-rich repeat region
`XP_057781685.1`	Pfam	`PF25019`	LRR_R13L1-DRL21	Repeat	660	784	6.9e-50	168.9	R13L1/DRL21 LRRs
`XP_057781685.1`	Pfam	`PF23247`	LRR_RPS2	Repeat	750	867	7.4e-15	56.0	Plant disease resistance protein RPS2-like, leucine-rich repeats

cDNA / CDS / Protein 序列

下载基因组 DNA（仅基因区域）

每个公开基因均提供参考注释对应的转录本序列；蛋白编码基因另提供 CDS 和蛋白序列。非编码 RNA 不适用 CDS 或蛋白下载。真实 accession 的版本后缀予以保留。

cDNA

3 records

下载 cDNA FASTA

XR_009093625.1
AATGCATAGAAGTTTCTATGTAACCGATTTATAAAGGTATCATATTTATATATTTTAATACATTTACCACATAGTCAAAGTCATAGTTTTAAAAAAGTGTCGGCAAAGATTAAATATATAAAATGAAAAAAGAAAACCTTATCTTCGAATGAAAGGCTGTAAACTCTTCTGCTTGAACACTCATCCAATTCTATTCCATAGCTTTCTCTCTCTCACTCAATTTCTCTCTCTCTCTCTCCTCAAAAAAATTCTCTCTTTCT...

XR_009093624.1
AATGCATAGAAGTTTCTATGTAACCGATTTATAAAGGTATCATATTTATATATTTTAATACATTTACCACATAGTCAAAGTCATAGTTTTAAAAAAGTGTCGGCAAAGATTAAATATATAAAATGAAAAAAGAAAACCTTATCTTCGAATGAAAGGCTGTAAACTCTTCTGCTTGAACACTCATCCAATTCTATTCCATAGCTTTCTCTCTCTCACTCAATTTCTCTCTCTCTCTCTCCTCAAAAAAATTCTCTCTTTCT...

CDS

1 records

下载 CDS FASTA

LOC130999989
ATGGAAGAACCTCTTGCTGCCGCCGTCCTTCAAGCTCCAATTGAAAACCTCATCGACTTTCTGAAGAATGAGATCTCTCAAATCCAAGGTGTCGACGAAGAAGCAGCAAAGCTAGCTGGGACTCTCGAAATCATCCAGAAATTCTTGAACCACGCGGAGTCGGGCACCATCACCGGCGAAGATGTCAAGAGCTGGCTGAGGAAGCTTGAAGACGTGGCGTTCGATGCTGACAATGTTTTGGATAAGTTCAACTATCATCG...

Protein

1 records

下载 Protein FASTA

XP_057781685.1
MEEPLAAAVLQAPIENLIDFLKNEISQIQGVDEEAAKLAGTLEIIQKFLNHAESGTITGEDVKSWLRKLEDVAFDADNVLDKFNYHRLSEQIKPKKAKVLSFFKHIPRSRKMALKIKKIRENLECINKDAAVLGLKERLAAAVPTLHDADASETDSYALDPIFIGRDDVVSEIVEMLTNSITTDERRVSISIVGMGGLGKTALTRKVFNHEMVKTRFASHIWVHVSPNFEPITLLKKILNNLASHHQVENASRQVVLTKL...

上下游序列下载

upstream/downstream 最大各 10000 bp。负链基因会自动反向互补，使最终 FASTA 为转录方向 5′→3′。

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JBrowse

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