Gene Card 基因详情

支持统一新 ID、NCBI Gene ID、GeneID、locus_tag、Transcript ID、Protein ID，以及已人工核对的文献基因名查询。页面会先解析到丹参统一基因，再整合坐标、序列、注释、亚细胞定位、EMS 突变和下载入口。

当前解析结果

`SmilChr08G000493`

染色体: Chr08 坐标: 3556320-3560562 链方向: - 类型: protein_coding

基本信息

统一新 Gene ID	`SmilChr08G000493`
名称	SmilChr08G000493
描述	cell division cycle protein 48 homolog
染色体 / SeqID	Chr08 / NC_080394.1
坐标与链方向	3556320 - 3560562 / `-`

ID 对照

NCBI Gene ID	`LOC131000085`
GeneID	`131000085`
locus_tag	`-`
NCBI Name	`LOC131000085`
原始查询	`SmilChr08G000493`

查看完整 ID 对照表

功能注释

来源	GFF basic annotation; NCBI GO GAF; KEGG smil; Pfam-A/HMMER; Arabidopsis/Rice homolog
描述	cell division cycle protein 48 homolog
产物	cell division cycle protein 48 homolog
Arabidopsis	`AT5G03340` (AtCDC48C) ATPase, AAA-type, CDC48 protein [Source:NCBI gene (formerly Entrezgene);Acc:831870] identity=92; qcov=0.939; evalue=0; confidence=high
Rice	`Os03g0151800` (OsCDC48) - identity=90.9; qcov=0.925; evalue=0; confidence=high
GO	GO:0005524 (ATP binding); GO:0005634 (nucleus); GO:0005829 (cytosol); GO:0016887 (ATP hydrolysis activity); GO:0030433 (GO:0030433); GO:0030970 (retrograde protein transport, ER to cytosol); GO:0031593 (polyubiquitin modification-dependent protein binding); GO:0034098 (VCP-NPL4-UFD1 AAA ATPase complex); GO:0051228 (mitotic spindle disassembly); GO:0071712 (GO:0071712); GO:0097352 (autophagosome maturation)
KEGG	smil04141 (Protein processing in endoplasmic reticulum - Salvia miltiorrhiza (redroot sage))
Pfam	PF00004 (AAA); PF02359 (CDC48_N); PF02933 (CDC48_2); PF07728 (AAA_5); PF17862 (AAA_lid_3)
InterPro	-
eggNOG	-
NR	GeneID:131000085

打开注释模块

亚细胞定位 Top 5

Rank	定位位置	中文	Score	Protein ID
1	Cytoplasm	细胞质	0.80000	`XP_057781836.1`
2	Cytosol	细胞质基质	0.80000	`XP_057781836.1`
3	Nucleus	细胞核	0.40000	`XP_057781836.1`
4	Endoplasmic reticulum	内质网	0.20000	`XP_057781836.1`
5	Chromosome	染色体	0.00000	`XP_057781836.1`

进入亚细胞定位查询

EMS 诱变突变

下表显示该基因在丹参 EMS 材料中的前 12 个候选突变；完整结果可进入 EMS 突变库继续筛选或下载。

位置	REF	ALT	类型	影响	携带材料数	材料
`Chr8:3556543`	`C`	`T`	EMS_canonical_SNV	CDS_variant	2	B29,C44
`Chr8:3556549`	`G`	`A`	EMS_canonical_SNV	CDS_variant	2	C34,C43
`Chr8:3556569`	`C`	`T`	EMS_canonical_SNV	CDS_variant	2	B62,C24
`Chr8:3556573`	`G`	`A`	EMS_canonical_SNV	CDS_variant	4	B122,B80,C62,D11
`Chr8:3556588`	`G`	`A`	EMS_canonical_SNV	CDS_variant	4	B4,B76,C44,D10
`Chr8:3556711`	`G`	`A`	EMS_canonical_SNV	CDS_variant	2	A21,B28
`Chr8:3557039`	`G`	`A`	EMS_canonical_SNV	CDS_variant	4	B120,B138,B90,B92
`Chr8:3557544`	`G`	`A`	EMS_canonical_SNV	CDS_variant	2	A21,B28
`Chr8:3557881`	`C`	`T`	EMS_canonical_SNV	CDS_variant	1	B104
`Chr8:3557918`	`G`	`A`	EMS_canonical_SNV	CDS_variant	4	B32,B6,C48,C67
`Chr8:3557929`	`C`	`T`	EMS_canonical_SNV	CDS_variant	2	B5,C44
`Chr8:3557948`	`G`	`A`	EMS_canonical_SNV	CDS_variant	1	C52

进入 EMS 突变库

预测功能结构域

结构域结果来自 Pfam-A HMM 数据库和 HMMER hmmscan；位置为对应蛋白序列上的氨基酸坐标。

XP_057781836.1

852 aa

426

852

CDC48_N

CDC48_2

AAA_5

AAA

AAA_lid_3

AAA

AAA_lid_3

PF02359 CDC48_N 75-156 aa PF02933 CDC48_2 176-239 aa PF07728 AAA_5 290-408 aa PF00004 AAA 290-419 aa PF17862 AAA_lid_3 442-483 aa PF00004 AAA 563-696 aa PF17862 AAA_lid_3 718-757 aa

Protein ID	来源	结构域编号	结构域名称	类型	起始 aa	终止 aa	E-value	Score	说明
`XP_057781836.1`	Pfam	`PF02359`	CDC48_N	Domain	75	156	2.9e-23	82.6	Cell division protein 48 (CDC48), N-terminal domain
`XP_057781836.1`	Pfam	`PF02933`	CDC48_2	Domain	176	239	8.6e-12	45.2	Cell division protein 48 (CDC48), domain 2
`XP_057781836.1`	Pfam	`PF07728`	AAA_5	Domain	290	408	1.5e-10	42.0	AAA domain (dynein-related subfamily)
`XP_057781836.1`	Pfam	`PF00004`	AAA	Domain	290	419	1.3e-97	323.9	ATPase family associated with various cellular activities (AAA)
`XP_057781836.1`	Pfam	`PF17862`	AAA_lid_3	Domain	442	483	5.3e-31	106.5	AAA+ lid domain
`XP_057781836.1`	Pfam	`PF00004`	AAA	Domain	563	696	1.3e-97	323.9	ATPase family associated with various cellular activities (AAA)
`XP_057781836.1`	Pfam	`PF17862`	AAA_lid_3	Domain	718	757	5.3e-31	106.5	AAA+ lid domain

cDNA / CDS / Protein 序列

下载基因组 DNA（仅基因区域）

每个公开基因均提供参考注释对应的转录本序列；蛋白编码基因另提供 CDS 和蛋白序列。非编码 RNA 不适用 CDS 或蛋白下载。真实 accession 的版本后缀予以保留。

cDNA

1 records

下载 cDNA FASTA

XM_057925853.1
CAACTAGTATATGAATTTTAATCTAAATAAGGTGAAGGAAAAGAAAGTCAGTTGAATTATAGAAGAAGTGCCTATATATATGCACCGATTATACACACATCTACTATCTCTATTTCTCTACATTTGCAACTCACAGCTCCCTTTCTTCTCCCAAGCGAAACTACCAAGTACCAACGCGCATCTCCAGATTCTCCAACACCGCAATTCTCAGATCATGAGCAACCAAGCCGAGTCCTCCGATTCGAAAGGTGGGAAGAAGG...

CDS

1 records

下载 CDS FASTA

LOC131000085
ATGCACCGATTATACACACATCTACTATCTCTATTTCTCTACATTTGCAACTCACAGCTCCCTTTCTTCTCCCAAGCGAAACTACCAAGTACCAACGCGCATCTCCAGATTCTCCAACACCGCAATTCTCAGATCATGAGCAACCAAGCCGAGTCCTCCGATTCGAAAGGTGGGAAGAAGGACTTCTCAACCGCGATTTTAGAGAGGAAAAAGGCGGCCAACCGCCTCGTCGTCGATGAGGCGGTCAACGACGACAACTC...

Protein

1 records

下载 Protein FASTA

XP_057781836.1
MHRLYTHLLSLFLYICNSQLPFFSQAKLPSTNAHLQILQHRNSQIMSNQAESSDSKGGKKDFSTAILERKKAANRLVVDEAVNDDNSVVSLHPATMEKLQIFRGDTILIKGKKRKDTVCIALADDACEEPKIRMNKVVRSNLRVRLGDVVSVHQCPDVKYGKRVHILPMDDTIEGLTGDLFDAYLKPYFLEAYRPVRKGDHLLVRGGMRSVEFKVVETDPGEYCVVAPDTEIFCEGEPIRREDEDRLDEVGYDDVGGVRK...

上下游序列下载

upstream/downstream 最大各 10000 bp。负链基因会自动反向互补，使最终 FASTA 为转录方向 5′→3′。

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