Gene Card 基因详情

支持统一新 ID、NCBI Gene ID、GeneID、locus_tag、Transcript ID、Protein ID，以及已人工核对的文献基因名查询。页面会先解析到丹参统一基因，再整合坐标、序列、注释、亚细胞定位、EMS 突变和下载入口。

当前解析结果

`SmilChr08G000555`

染色体: Chr08 坐标: 4025825-4033658 链方向: + 类型: protein_coding

基本信息

统一新 Gene ID	`SmilChr08G000555`
名称	SmilChr08G000555
描述	DNA repair protein RAD5A
染色体 / SeqID	Chr08 / NC_080394.1
坐标与链方向	4025825 - 4033658 / `+`

ID 对照

NCBI Gene ID	`LOC131000144`
GeneID	`131000144`
locus_tag	`-`
NCBI Name	`LOC131000144`
原始查询	`SmilChr08G000555`

查看完整 ID 对照表

功能注释

来源	GFF basic annotation; NCBI GO GAF; Pfam-A/HMMER; Arabidopsis/Rice homolog
描述	DNA repair protein RAD5A
产物	DNA repair protein RAD5A
Arabidopsis	`AT5G22750` (RAD5) DNA/RNA helicase protein [Source:NCBI gene (formerly Entrezgene);Acc:832338] identity=65.5; qcov=1.01; evalue=0; confidence=high
Rice	`Os02g0527100` - identity=66.8; qcov=0.736; evalue=0; confidence=high
GO	GO:0003676 (nucleic acid binding); GO:0005524 (ATP binding); GO:0008270 (zinc ion binding); GO:0016818 (hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides); GO:0140658 (ATP-dependent chromatin remodeler activity)
KEGG	-
Pfam	PF00097 (zf-C3HC4); PF00176 (SNF2-rel_dom); PF00270 (DEAD); PF00271 (Helicase_C); PF08797 (HIRAN); PF13445 (zf-RING_UBOX); PF13639 (zf-RING_2); PF13920 (zf-C3HC4_3); PF13923 (zf-C3HC4_2); PF14447 (Prok-RING_4); PF24559 (UBA_RAD5A)
InterPro	-
eggNOG	-
NR	GeneID:131000144

打开注释模块

亚细胞定位 Top 5

Rank	定位位置	中文	Score	Protein ID
1	Nucleus	细胞核	1.00000	`XP_057781904.1`
2	Chromosome	染色体	0.00000	`XP_057781904.1`
3	Centromere	着丝粒	0.00000	`XP_057781904.1`
4	Chromatin	染色质	0.00000	`XP_057781904.1`
5	Telomere	端粒	0.00000	`XP_057781904.1`

进入亚细胞定位查询

EMS 诱变突变

下表显示该基因在丹参 EMS 材料中的前 12 个候选突变；完整结果可进入 EMS 突变库继续筛选或下载。

位置	REF	ALT	类型	影响	携带材料数	材料
`Chr8:4026344`	`G`	`A`	EMS_canonical_SNV	CDS_variant	1	C78
`Chr8:4027036`	`C`	`T`	EMS_canonical_SNV	CDS_variant	2	C64,C66
`Chr8:4027240`	`C`	`T`	EMS_canonical_SNV	CDS_variant	5	B124,B2,B97,C28,C38
`Chr8:4027252`	`C`	`T`	EMS_canonical_SNV	CDS_variant	1	B104
`Chr8:4027312`	`G`	`A`	EMS_canonical_SNV	CDS_variant	1	C25
`Chr8:4027801`	`G`	`A`	EMS_canonical_SNV	CDS_variant	5	B124,B2,B97,C28,C38
`Chr8:4027806`	`C`	`T`	EMS_canonical_SNV	CDS_variant	3	B5,B86,B88
`Chr8:4028511`	`G`	`A`	EMS_canonical_SNV	CDS_variant	1	B104
`Chr8:4030652`	`G`	`A`	EMS_canonical_SNV	CDS_variant	1	B104
`Chr8:4031509`	`G`	`A`	EMS_canonical_SNV	CDS_variant	3	A11,B19,B98
`Chr8:4031611`	`G`	`A`	EMS_canonical_SNV	CDS_variant	1	D11
`Chr8:4032083`	`G`	`A`	EMS_canonical_SNV	CDS_variant	2	B5,B88

进入 EMS 突变库

预测功能结构域

结构域结果来自 Pfam-A HMM 数据库和 HMMER hmmscan；位置为对应蛋白序列上的氨基酸坐标。

XP_057781904.1

1044 aa

522

1044

UBA_RAD5A

HIRAN

SNF2-rel_dom

DEAD

zf-C3HC4_3

zf-C3HC4_2

zf-RING_2

zf-RING_UBOX

zf-C3HC4

Prok-RING_4

Helicase_C

PF24559 UBA_RAD5A 6-49 aa PF08797 HIRAN 129-236 aa PF00176 SNF2-rel_dom 365-752 aa PF00270 DEAD 493-625 aa PF13920 zf-C3HC4_3 806-854 aa PF13923 zf-C3HC4_2 808-848 aa PF13639 zf-RING_2 808-849 aa PF13445 zf-RING_UBOX 809-846 aa PF00097 zf-C3HC4 809-848 aa PF14447 Prok-RING_4 809-855 aa PF00271 Helicase_C 879-991 aa

XP_057781905.1

857 aa

428

857

UBA_RAD5A

HIRAN

SNF2-rel_dom

DEAD

zf-C3HC4_3

zf-RING_2

zf-C3HC4_2

zf-RING_UBOX

zf-C3HC4

PF24559 UBA_RAD5A 6-49 aa PF08797 HIRAN 129-236 aa PF00176 SNF2-rel_dom 365-752 aa PF00270 DEAD 491-625 aa PF13920 zf-C3HC4_3 806-849 aa PF13639 zf-RING_2 808-848 aa PF13923 zf-C3HC4_2 808-848 aa PF13445 zf-RING_UBOX 809-846 aa PF00097 zf-C3HC4 809-848 aa

XP_057781906.1

847 aa

424

847

UBA_RAD5A

HIRAN

SNF2-rel_dom

DEAD

zf-C3HC4_3

zf-RING_2

zf-C3HC4_2

zf-C3HC4

zf-RING_UBOX

PF24559 UBA_RAD5A 6-49 aa PF08797 HIRAN 129-236 aa PF00176 SNF2-rel_dom 365-752 aa PF00270 DEAD 491-625 aa PF13920 zf-C3HC4_3 806-847 aa PF13639 zf-RING_2 808-847 aa PF13923 zf-C3HC4_2 808-847 aa PF00097 zf-C3HC4 809-846 aa PF13445 zf-RING_UBOX 809-846 aa

Protein ID	来源	结构域编号	结构域名称	类型	起始 aa	终止 aa	E-value	Score	说明
`XP_057781904.1`	Pfam	`PF24559`	UBA_RAD5A	Domain	6	49	7e-26	90.2	DNA repair protein RAD5A UBA domain
`XP_057781904.1`	Pfam	`PF08797`	HIRAN	Domain	129	236	1.5e-14	54.3	HIRAN domain
`XP_057781904.1`	Pfam	`PF00176`	SNF2-rel_dom	Domain	365	752	5.7e-75	252.8	SNF2-related domain
`XP_057781904.1`	Pfam	`PF00270`	DEAD	Domain	493	625	5.9e-06	26.8	DEAD/DEAH box helicase
`XP_057781904.1`	Pfam	`PF13920`	zf-C3HC4_3	Domain	806	854	3.5e-10	40.2	Zinc finger, C3HC4 type (RING finger)
`XP_057781904.1`	Pfam	`PF13923`	zf-C3HC4_2	Domain	808	848	6.1e-09	36.2	Zinc finger, C3HC4 type (RING finger)
`XP_057781904.1`	Pfam	`PF13639`	zf-RING_2	Domain	808	849	6.7e-08	33.4	Ring finger domain
`XP_057781904.1`	Pfam	`PF13445`	zf-RING_UBOX	Domain	809	846	2.6e-09	37.6	RING-type zinc-finger
`XP_057781904.1`	Pfam	`PF00097`	zf-C3HC4	Domain	809	848	1.8e-09	38.0	Zinc finger, C3HC4 type (RING finger)
`XP_057781904.1`	Pfam	`PF14447`	Prok-RING_4	Family	809	855	1.2e-06	29.1	Prokaryotic RING finger family 4
`XP_057781904.1`	Pfam	`PF00271`	Helicase_C	Domain	879	991	5.7e-22	78.8	Helicase conserved C-terminal domain
`XP_057781905.1`	Pfam	`PF24559`	UBA_RAD5A	Domain	6	49	5.6e-26	90.5	DNA repair protein RAD5A UBA domain
`XP_057781905.1`	Pfam	`PF08797`	HIRAN	Domain	129	236	1.1e-14	54.7	HIRAN domain
`XP_057781905.1`	Pfam	`PF00176`	SNF2-rel_dom	Domain	365	752	4.3e-75	253.2	SNF2-related domain
`XP_057781905.1`	Pfam	`PF00270`	DEAD	Domain	491	625	5.2e-06	27.0	DEAD/DEAH box helicase
`XP_057781905.1`	Pfam	`PF13920`	zf-C3HC4_3	Domain	806	849	2.5e-08	34.3	Zinc finger, C3HC4 type (RING finger)
`XP_057781905.1`	Pfam	`PF13639`	zf-RING_2	Domain	808	848	2.3e-07	31.7	Ring finger domain
`XP_057781905.1`	Pfam	`PF13923`	zf-C3HC4_2	Domain	808	848	4.3e-09	36.7	Zinc finger, C3HC4 type (RING finger)
`XP_057781905.1`	Pfam	`PF13445`	zf-RING_UBOX	Domain	809	846	4e-08	33.9	RING-type zinc-finger
`XP_057781905.1`	Pfam	`PF00097`	zf-C3HC4	Domain	809	848	1.3e-09	38.5	Zinc finger, C3HC4 type (RING finger)
`XP_057781906.1`	Pfam	`PF24559`	UBA_RAD5A	Domain	6	49	5.6e-26	90.5	DNA repair protein RAD5A UBA domain
`XP_057781906.1`	Pfam	`PF08797`	HIRAN	Domain	129	236	1.1e-14	54.7	HIRAN domain
`XP_057781906.1`	Pfam	`PF00176`	SNF2-rel_dom	Domain	365	752	4.2e-75	253.2	SNF2-related domain
`XP_057781906.1`	Pfam	`PF00270`	DEAD	Domain	491	625	5.1e-06	27.0	DEAD/DEAH box helicase
`XP_057781906.1`	Pfam	`PF13920`	zf-C3HC4_3	Domain	806	847	8.2e-07	29.4	Zinc finger, C3HC4 type (RING finger)
`XP_057781906.1`	Pfam	`PF13639`	zf-RING_2	Domain	808	847	2.2e-06	28.5	Ring finger domain
`XP_057781906.1`	Pfam	`PF13923`	zf-C3HC4_2	Domain	808	847	1.4e-08	35.1	Zinc finger, C3HC4 type (RING finger)
`XP_057781906.1`	Pfam	`PF00097`	zf-C3HC4	Domain	809	846	4.4e-09	36.8	Zinc finger, C3HC4 type (RING finger)
`XP_057781906.1`	Pfam	`PF13445`	zf-RING_UBOX	Domain	809	846	6.6e-09	36.3	RING-type zinc-finger

cDNA / CDS / Protein 序列

下载基因组 DNA（仅基因区域）

每个公开基因均提供参考注释对应的转录本序列；蛋白编码基因另提供 CDS 和蛋白序列。非编码 RNA 不适用 CDS 或蛋白下载。真实 accession 的版本后缀予以保留。

cDNA

3 records

下载 cDNA FASTA

XM_057925922.1
AGAGGGAGAGCAGTAAATAAAGATGGCGGGAAGTGTTTCGTACCTCGCACACTTCCCTCTTCATTATATCGAACCGACCACCCGCCACTTCCACTCTTTTTCTTTTTTTTGAAAAAAAGCAAAGCAGCAAATGTAAAGAAATTCTAGGGTTTATAAATACCTAAATTAAAAACCCCAAATCTAAAGAAAGCGTTTCGATTACATGTTTGATATCTCCATTTTCTATTCCAATTGCCGGCGGTCGTGATGGGAAACAAGGC...

XM_057925923.1
GAGGGAGAGCAGTAAATAAAGATGGCGGGAAGTGTTTCGTACCTCGCACACTTCCCTCTTCATTATATCGAACCGACCACCCGCCACTTCCACTCTTTTTCTTTTTTTTGAAAAAAAGCAAAGCAGCAAATGTAAAGAAATTCTAGGGTTTATAAATACCTAAATTAAAAACCCCAAATCTAAAGAAAGCGTTTCGATTACATGTTTGATATCTCCATTTTCTATTCCAATTGCCGGCGGTCGTGATGGGAAACAAGGCC...

CDS

3 records

下载 CDS FASTA

LOC131000144
ATGGGAAACAAGGCCACCGAAGAAATCATCTCCACTGTTCGGTCGATCGTCGGCGGTGAATTTGCCGACATGGACATAATTCGAGCGCTTCACTTGGCCAACAATGACCCAACCGCCGCGATTAACATCATCTTCGACACGCCAAGGAGCTTCAGGAAGCCTGATTTTCCCAAGAAGTCCGAGCCCTCTAAGAGCAGTCTCAATGCGGAGCCTCCGGTTGTCGAGTCTACTGTAAAGCAGAACGTTGGTCGGCTAGAGGA...

Protein

3 records

下载 Protein FASTA

XP_057781904.1
MGNKATEEIISTVRSIVGGEFADMDIIRALHLANNDPTAAINIIFDTPRSFRKPDFPKKSEPSKSSLNAEPPVVESTVKQNVGRLEDSDSAARSNVNLKSRSGSNQCGGNGCADSGKSEEMGSEWWFVGSGEVTGLSTCKGRTLKPGDEVNFTFPAQKKLTTPSPGKIGGGRGRQVATCSEIIRFSTSACGEIGRIPNEWGRCLLPLVRDKKVCVKGCCKSAPPVLGIMDSVVLSISIYANSSMFQKSQQMSLKAASNSA...

XP_057781905.1
MGNKATEEIISTVRSIVGGEFADMDIIRALHLANNDPTAAINIIFDTPRSFRKPDFPKKSEPSKSSLNAEPPVVESTVKQNVGRLEDSDSAARSNVNLKSRSGSNQCGGNGCADSGKSEEMGSEWWFVGSGEVTGLSTCKGRTLKPGDEVNFTFPAQKKLTTPSPGKIGGGRGRQVATCSEIIRFSTSACGEIGRIPNEWGRCLLPLVRDKKVCVKGCCKSAPPVLGIMDSVVLSISIYANSSMFQKSQQMSLKAASNSA...

上下游序列下载

upstream/downstream 最大各 10000 bp。负链基因会自动反向互补，使最终 FASTA 为转录方向 5′→3′。

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