Gene Card 基因详情

支持统一新 ID、NCBI Gene ID、GeneID、locus_tag、Transcript ID、Protein ID，以及已人工核对的文献基因名查询。页面会先解析到丹参统一基因，再整合坐标、序列、注释、亚细胞定位、EMS 突变和下载入口。

当前解析结果

`SmilChr08G000835`

染色体: Chr08 坐标: 6177032-6184935 链方向: - 类型: protein_coding

基本信息

统一新 Gene ID	`SmilChr08G000835`
名称	SmilChr08G000835
描述	poly [ADP-ribose] polymerase 2
染色体 / SeqID	Chr08 / NC_080394.1
坐标与链方向	6177032 - 6184935 / `-`

ID 对照

NCBI Gene ID	`LOC131000418`
GeneID	`131000418`
locus_tag	`-`
NCBI Name	`LOC131000418`
原始查询	`SmilChr08G000835`

查看完整 ID 对照表

功能注释

来源	GFF basic annotation; NCBI GO GAF; KEGG smil; Pfam-A/HMMER; Arabidopsis/Rice homolog
描述	poly [ADP-ribose] polymerase 2
产物	poly [ADP-ribose] polymerase 2
Arabidopsis	`AT4G02390` (PARP2) poly(ADP-ribose) polymerase [Source:NCBI gene (formerly Entrezgene);Acc:828049] identity=60.6; qcov=0.829; evalue=0; confidence=high
Rice	`Os01g0351200` (PARP2A) - identity=58.5; qcov=0.859; evalue=0; confidence=high
GO	GO:0003950 (NAD+ poly-ADP-ribosyltransferase activity); GO:0006353 (DNA-templated transcription termination)
KEGG	smil03410 (Base excision repair - Salvia miltiorrhiza (redroot sage))
Pfam	PF00644 (PARP); PF02037 (SAP); PF02877 (PARP_reg); PF05406 (WGR)
InterPro	-
eggNOG	-
NR	GeneID:131000418

打开注释模块

亚细胞定位 Top 5

Rank	定位位置	中文	Score	Protein ID
1	Nucleus	细胞核	1.00000	`XP_057782299.1`
2	Nucleoplasm	核质	0.80000	`XP_057782299.1`
3	Nucleolus	核仁	0.40000	`XP_057782299.1`
4	Nucleolar fibrillar center	Nucleolar fibrillar center	0.40000	`XP_057782299.1`
5	Chromosome	染色体	0.20000	`XP_057782299.1`

进入亚细胞定位查询

EMS 诱变突变

下表显示该基因在丹参 EMS 材料中的前 12 个候选突变；完整结果可进入 EMS 突变库继续筛选或下载。

位置	REF	ALT	类型	影响	携带材料数	材料
`Chr8:6179021`	`C`	`T`	EMS_canonical_SNV	CDS_variant	1	B101
`Chr8:6179364`	`G`	`A`	EMS_canonical_SNV	CDS_variant	3	B38,B39,C72
`Chr8:6180710`	`C`	`T`	EMS_canonical_SNV	CDS_variant	2	B98,D7
`Chr8:6180911`	`G`	`GT`	1bp_insertion	frameshift_variant	2	B109,B117
`Chr8:6180911`	`G`	`GT`	1bp_insertion	CDS_variant	2	B109,B117
`Chr8:6180939`	`C`	`T`	EMS_canonical_SNV	CDS_variant	2	A1,D10
`Chr8:6181143`	`C`	`T`	EMS_canonical_SNV	CDS_variant	3	B37,C6,C9
`Chr8:6182087`	`C`	`T`	EMS_canonical_SNV	CDS_variant	1	D10
`Chr8:6182565`	`G`	`A`	EMS_canonical_SNV	CDS_variant	5	B113,B55,C21,C36,C77
`Chr8:6182580`	`C`	`T`	EMS_canonical_SNV	CDS_variant	1	B104
`Chr8:6183450`	`AT`	`A`	1bp_deletion	frameshift_variant	6	B42,B43,B46,C15,C16,C61
`Chr8:6183904`	`C`	`T`	EMS_canonical_SNV	CDS_variant	1	C87

进入 EMS 突变库

预测功能结构域

结构域结果来自 Pfam-A HMM 数据库和 HMMER hmmscan；位置为对应蛋白序列上的氨基酸坐标。

XP_057782299.1

761 aa

380

761

SAP

WGR

PARP_reg

PARP

PF02037 SAP 5-38 aa PF02037 SAP 75-105 aa PF02037 SAP 142-172 aa PF02037 SAP 209-242 aa PF05406 WGR 295-374 aa PF02877 PARP_reg 412-542 aa PF00644 PARP 556-757 aa

XP_057782300.1

760 aa

380

760

SAP

WGR

PARP_reg

PARP

PF02037 SAP 5-38 aa PF02037 SAP 75-105 aa PF02037 SAP 141-171 aa PF02037 SAP 208-241 aa PF05406 WGR 294-373 aa PF02877 PARP_reg 411-541 aa PF00644 PARP 555-756 aa

Protein ID	来源	结构域编号	结构域名称	类型	起始 aa	终止 aa	E-value	Score	说明
`XP_057782299.1`	Pfam	`PF02037`	SAP	Domain	5	38	4.5e-39	132.0	SAP domain
`XP_057782299.1`	Pfam	`PF02037`	SAP	Domain	75	105	4.5e-39	132.0	SAP domain
`XP_057782299.1`	Pfam	`PF02037`	SAP	Domain	142	172	4.5e-39	132.0	SAP domain
`XP_057782299.1`	Pfam	`PF02037`	SAP	Domain	209	242	4.5e-39	132.0	SAP domain
`XP_057782299.1`	Pfam	`PF05406`	WGR	Domain	295	374	5e-24	84.9	WGR domain
`XP_057782299.1`	Pfam	`PF02877`	PARP_reg	Domain	412	542	4.4e-40	137.6	Poly(ADP-ribose) polymerase, regulatory domain
`XP_057782299.1`	Pfam	`PF00644`	PARP	Domain	556	757	4.5e-82	275.1	Poly(ADP-ribose) polymerase catalytic domain
`XP_057782300.1`	Pfam	`PF02037`	SAP	Domain	5	38	4.5e-39	132.1	SAP domain
`XP_057782300.1`	Pfam	`PF02037`	SAP	Domain	75	105	4.5e-39	132.1	SAP domain
`XP_057782300.1`	Pfam	`PF02037`	SAP	Domain	141	171	4.5e-39	132.1	SAP domain
`XP_057782300.1`	Pfam	`PF02037`	SAP	Domain	208	241	4.5e-39	132.1	SAP domain
`XP_057782300.1`	Pfam	`PF05406`	WGR	Domain	294	373	4.7e-24	85.0	WGR domain
`XP_057782300.1`	Pfam	`PF02877`	PARP_reg	Domain	411	541	4.1e-40	137.7	Poly(ADP-ribose) polymerase, regulatory domain
`XP_057782300.1`	Pfam	`PF00644`	PARP	Domain	555	756	4.5e-82	275.1	Poly(ADP-ribose) polymerase catalytic domain

cDNA / CDS / Protein 序列

下载基因组 DNA（仅基因区域）

每个公开基因均提供参考注释对应的转录本序列；蛋白编码基因另提供 CDS 和蛋白序列。非编码 RNA 不适用 CDS 或蛋白下载。真实 accession 的版本后缀予以保留。

cDNA

2 records

下载 cDNA FASTA

XM_057926317.1
GATTTTAATTATTTTTAAATCGTAGAAGACGCGCCAACAAGTCGTGCAGTGAGGATTTCGGGGCAAGCTGCTTCTCTAGTAAGCTTCTCATTTTCTCAAGTCCCAGACTCACTTATATACCTCCAATTTAAAAAACCCTCAACTTCTCACTCAAATTCTCTCTCCAACCTAAACAATGGCGACCAAGGATCTCAATGTGGACCAACTCCGGGACAAGCTGGCCAAGCGCGGCCTCAGCACTGCCGGACTAAAATCTACTC...

XM_057926316.1
GATTTTAATTATTTTTAAATCGTAGAAGACGCGCCAACAAGTCGTGCAGTGAGGATTTCGGGGCAAGCTGCTTCTCTAGTAAGCTTCTCATTTTCTCAAGTCCCAGACTCACTTATATACCTCCAATTTAAAAAACCCTCAACTTCTCACTCAAATTCTCTCTCCAACCTAAACAATGGCGACCAAGGATCTCAATGTGGACCAACTCCGGGACAAGCTGGCCAAGCGCGGCCTCAGCACTGCCGGACTAAAATCTACTC...

CDS

2 records

下载 CDS FASTA

LOC131000418
ATGGCGACCAAGGATCTCAATGTGGACCAACTCCGGGACAAGCTGGCCAAGCGCGGCCTCAGCACTGCCGGACTAAAATCTACTCTGGTTCGAAGACTTGAAGCTGCTATTAGAGACGAGAGCGATAAGCCGAAGGACTCAAAAGGTCGCAAAAGGCAGAGGGACGGTGAAGCCAAGGATGCCGATTCAGATGCGCCGGGGAAGCGGAAGGCCGTTGATGAGCTACATAGTATGACTGTAAAGCAGCTTCGCGAAGAGGC...

Protein

2 records

下载 Protein FASTA

XP_057782299.1
MATKDLNVDQLRDKLAKRGLSTAGLKSTLVRRLEAAIRDESDKPKDSKGRKRQRDGEAKDADSDAPGKRKAVDELHSMTVKQLREEASTRGVSAAGTKQELLERLSMADDKNASDNGQVEEENEEENEDASASQKVKAIDELRSMTVKQLRGEASIRGISAAGTKQELLERLSATDDKNASDNDQVEEKNGEENVDSSGPQKVKAIDELQKMTMKQLREEAAKRGVSASGTKKDLLDRLCTHNDNVSRDNNLVKEEAKEE...

XP_057782300.1
MATKDLNVDQLRDKLAKRGLSTAGLKSTLVRRLEAAIRDESDKPKDSKGRKRQRDGEAKDADSDAPGKRKAVDELHSMTVKQLREEASTRGVSAAGTKQELLERLSMADDKNASDNGQEEENEEENEDASASQKVKAIDELRSMTVKQLRGEASIRGISAAGTKQELLERLSATDDKNASDNDQVEEKNGEENVDSSGPQKVKAIDELQKMTMKQLREEAAKRGVSASGTKKDLLDRLCTHNDNVSRDNNLVKEEAKEEK...

上下游序列下载

upstream/downstream 最大各 10000 bp。负链基因会自动反向互补，使最终 FASTA 为转录方向 5′→3′。

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