Gene Card 基因详情

支持统一新 ID、NCBI Gene ID、GeneID、locus_tag、Transcript ID、Protein ID，以及已人工核对的文献基因名查询。页面会先解析到丹参统一基因，再整合坐标、序列、注释、亚细胞定位、EMS 突变和下载入口。

当前解析结果

`SmilChr08G001006`

染色体: Chr08 坐标: 7568982-7571349 链方向: + 类型: protein_coding

基本信息

统一新 Gene ID	`SmilChr08G001006`
名称	SmilChr08G001006
描述	cinnamoyl-CoA reductase CAD2-like
染色体 / SeqID	Chr08 / NC_080394.1
坐标与链方向	7568982 - 7571349 / `+`

ID 对照

NCBI Gene ID	`LOC131000590`
GeneID	`131000590`
locus_tag	`-`
NCBI Name	`LOC131000590`
原始查询	`SmilChr08G001006`

查看完整 ID 对照表

功能注释

来源	GFF basic annotation; NCBI GO GAF; Pfam-A/HMMER; Arabidopsis/Rice homolog
描述	cinnamoyl-CoA reductase CAD2-like
产物	cinnamoyl-CoA reductase CAD2-like
Arabidopsis	`AT5G58490` (AT5G58490) NAD(P)-binding Rossmann-fold superfamily protein [Source:NCBI gene (formerly Entrezgene);Acc:835962] identity=62.8; qcov=0.881; evalue=1.78e-125; confidence=high
Rice	`Os03g0818200` (OsCCR22) - identity=56.9; qcov=0.856; evalue=6.75e-92; confidence=high
GO	GO:0016616 (oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor)
KEGG	-
Pfam	PF01073 (3Beta_HSD); PF01370 (Epimerase); PF02719 (Polysacc_synt_2); PF05368 (NmrA); PF07993 (NAD_binding_4); PF08659 (KR); PF13460 (NAD_binding_10); PF16363 (GDP_Man_Dehyd)
InterPro	-
eggNOG	-
NR	GeneID:131000590

打开注释模块

亚细胞定位 Top 5

Rank	定位位置	中文	Score	Protein ID
1	Cytosol	细胞质基质	1.00000	`XP_057782581.1`
2	Cytoplasm	细胞质	0.80000	`XP_057782581.1`
3	Nucleus	细胞核	0.00000	`XP_057782581.1`
4	Chromosome	染色体	0.00000	`XP_057782581.1`
5	Centromere	着丝粒	0.00000	`XP_057782581.1`

进入亚细胞定位查询

EMS 诱变突变

下表显示该基因在丹参 EMS 材料中的前 12 个候选突变；完整结果可进入 EMS 突变库继续筛选或下载。

位置	REF	ALT	类型	影响	携带材料数	材料
`Chr8:7568999`	`G`	`GA`	1bp_insertion	frameshift_variant	80	A1,A13,A15,A2,B1,B103,B111,B113,B117,B121,B122,B124,B126,B131,B132,B138,B139,B140,B16,B27,B30,B31,B36,B38,B39,B42,B43,B52,B58,B59,B60,B61,B66,B69,B71,B73,B74,B8,B87,B88,B89,C1,C14,C18,C19,C2,C21,C25,C27,C3,C30,C32,C33,C38,C44,C46,C48,C49,C51,C52,C53,C56,C64,C68,C71,C72,C76,C78,C79,C8,C80,C81,C82,C84,C85,C9,D10,D5,D7,D9
`Chr8:7569022`	`GA`	`G`	1bp_deletion	frameshift_variant	18	A1,A22,A24,B103,B107,B131,B32,B33,B47,B5,B55,C3,C30,C49,C5,C53,C64,C83
`Chr8:7569027`	`T`	`TC`	1bp_insertion	frameshift_variant	35	A18,A22,B102,B11,B112,B113,B12,B129,B137,B23,B41,B55,B57,B67,B7,B71,B79,B83,B85,B86,B9,C12,C14,C15,C2,C23,C24,C37,C53,C58,C59,C7,C76,C81,C86
`Chr8:7569029`	`C`	`CCA`	2bp_insertion	frameshift_variant	57	A13,A14,A16,A18,A20,A23,A4,B10,B100,B106,B107,B108,B110,B120,B121,B122,B123,B125,B136,B139,B16,B20,B23,B24,B27,B30,B4,B44,B56,B61,B69,B7,B72,B81,B88,B98,C11,C16,C17,C18,C20,C29,C30,C35,C36,C39,C4,C45,C48,C55,C63,C69,C74,C78,D3,D5,D9
`Chr8:7569031`	`A`	`AC`	1bp_insertion	frameshift_variant	57	A10,A3,A4,A6,A7,A8,B102,B108,B111,B119,B126,B128,B130,B133,B135,B2,B21,B26,B29,B30,B31,B33,B36,B37,B40,B6,B64,B66,B69,B70,B74,B76,B78,B79,B8,B84,B87,B94,B95,B99,C1,C12,C27,C28,C34,C57,C6,C60,C62,C65,C67,C73,C74,C82,C87,D6,D8
`Chr8:7569035`	`G`	`A`	EMS_canonical_SNV	CDS_variant	2	B15,C19
`Chr8:7569293`	`C`	`T`	EMS_canonical_SNV	CDS_variant	2	B117,D10
`Chr8:7569347`	`C`	`T`	EMS_canonical_SNV	CDS_variant	5	B107,B120,B139,B75,B88
`Chr8:7569787`	`G`	`A`	EMS_canonical_SNV	CDS_variant	1	B136
`Chr8:7570785`	`G`	`A`	EMS_canonical_SNV	CDS_variant	1	C78
`Chr8:7571087`	`TG`	`T`	1bp_deletion	frameshift_variant	1	D7
`Chr8:7571087`	`TG`	`T`	1bp_deletion	CDS_variant	1	D7

进入 EMS 突变库

预测功能结构域

结构域结果来自 Pfam-A HMM 数据库和 HMMER hmmscan；位置为对应蛋白序列上的氨基酸坐标。

XP_057782581.1

334 aa

167

334

NmrA

Polysacc_synt_2

Epimerase

GDP_Man_Dehyd

NAD_binding_4

3Beta_HSD

NAD_binding_10

PF05368 NmrA 21-116 aa PF02719 Polysacc_synt_2 22-149 aa PF08659 KR 22-150 aa PF01370 Epimerase 22-256 aa PF16363 GDP_Man_Dehyd 24-209 aa PF07993 NAD_binding_4 24-219 aa PF01073 3Beta_HSD 24-251 aa PF13460 NAD_binding_10 26-153 aa

XP_057782582.1

320 aa

160

320

NmrA

Polysacc_synt_2

Epimerase

GDP_Man_Dehyd

NAD_binding_4

3Beta_HSD

NAD_binding_10

Protein ID	来源	结构域编号	结构域名称	类型	起始 aa	终止 aa	E-value	Score	说明
`XP_057782581.1`	Pfam	`PF05368`	NmrA	Family	21	116	1.7e-11	45.0	NmrA-like family
`XP_057782581.1`	Pfam	`PF02719`	Polysacc_synt_2	Family	22	149	2.5e-08	34.2	Polysaccharide biosynthesis protein
`XP_057782581.1`	Pfam	`PF08659`	KR	Family	22	150	1.8e-07	32.0	KR domain
`XP_057782581.1`	Pfam	`PF01370`	Epimerase	Family	22	256	3.9e-29	102.5	NAD dependent epimerase/dehydratase family
`XP_057782581.1`	Pfam	`PF16363`	GDP_Man_Dehyd	Domain	24	209	3.1e-18	67.0	GDP-mannose 4,6 dehydratase
`XP_057782581.1`	Pfam	`PF07993`	NAD_binding_4	Family	24	219	1.4e-11	44.8	Male sterility protein
`XP_057782581.1`	Pfam	`PF01073`	3Beta_HSD	Family	24	251	7e-21	75.2	3-beta hydroxysteroid dehydrogenase/isomerase family
`XP_057782581.1`	Pfam	`PF13460`	NAD_binding_10	Domain	26	153	3.6e-14	53.8	NAD(P)H-binding
`XP_057782582.1`	Pfam	`PF05368`	NmrA	Family	21	116	1.6e-11	45.1	NmrA-like family
`XP_057782582.1`	Pfam	`PF02719`	Polysacc_synt_2	Family	22	149	2.3e-08	34.3	Polysaccharide biosynthesis protein
`XP_057782582.1`	Pfam	`PF08659`	KR	Family	22	150	1.7e-07	32.1	KR domain
`XP_057782582.1`	Pfam	`PF01370`	Epimerase	Family	22	256	3.5e-29	102.6	NAD dependent epimerase/dehydratase family
`XP_057782582.1`	Pfam	`PF16363`	GDP_Man_Dehyd	Domain	24	209	2.8e-18	67.2	GDP-mannose 4,6 dehydratase
`XP_057782582.1`	Pfam	`PF07993`	NAD_binding_4	Family	24	219	1.3e-11	44.9	Male sterility protein
`XP_057782582.1`	Pfam	`PF01073`	3Beta_HSD	Family	24	251	6e-21	75.4	3-beta hydroxysteroid dehydrogenase/isomerase family
`XP_057782582.1`	Pfam	`PF13460`	NAD_binding_10	Domain	26	153	3.3e-14	53.9	NAD(P)H-binding

cDNA / CDS / Protein 序列

下载基因组 DNA（仅基因区域）

每个公开基因均提供参考注释对应的转录本序列；蛋白编码基因另提供 CDS 和蛋白序列。非编码 RNA 不适用 CDS 或蛋白下载。真实 accession 的版本后缀予以保留。

cDNA

2 records

下载 cDNA FASTA

XM_057926599.1
GAAACACTCGACTACATGAAAAAAAACACGTTCTCCACTAGACACTCCCACATGGTGATGAGCAAGGAAGGAGAAGTTGTCTGCGTCACCGGCGCCAGCGGCTTCATCGGCTCTTGGCTCGTCCACTTTCTCCTCCACCGCGGCTACGCCGTCCGCGCCACCGTCAAAAATCTAGGAGATGAGAGAGAAACGAAGCACTTGGAAGCCATGGAAGGAGCTGATTCCCGCCTTCGCCTCTTCCAGATTGATCTGCTTGATTA...

XM_057926598.1
ACACTCGACTACATGAAAAAAAACACGTTCTCCACTAGACACTCCCACATGGTGATGAGCAAGGAAGGAGAAGTTGTCTGCGTCACCGGCGCCAGCGGCTTCATCGGCTCTTGGCTCGTCCACTTTCTCCTCCACCGCGGCTACGCCGTCCGCGCCACCGTCAAAAATCTAGGAGATGAGAGAGAAACGAAGCACTTGGAAGCCATGGAAGGAGCTGATTCCCGCCTTCGCCTCTTCCAGATTGATCTGCTTGATTATGA...

CDS

2 records

下载 CDS FASTA

LOC131000590
ATGAAAAAAAACACGTTCTCCACTAGACACTCCCACATGGTGATGAGCAAGGAAGGAGAAGTTGTCTGCGTCACCGGCGCCAGCGGCTTCATCGGCTCTTGGCTCGTCCACTTTCTCCTCCACCGCGGCTACGCCGTCCGCGCCACCGTCAAAAATCTAGGAGATGAGAGAGAAACGAAGCACTTGGAAGCCATGGAAGGAGCTGATTCCCGCCTTCGCCTCTTCCAGATTGATCTGCTTGATTATGACTCCATTGTTGC...

Protein

2 records

下载 Protein FASTA

XP_057782581.1
MKKNTFSTRHSHMVMSKEGEVVCVTGASGFIGSWLVHFLLHRGYAVRATVKNLGDERETKHLEAMEGADSRLRLFQIDLLDYDSIVAAVSGAAGVFHLASPCIIDQIEDPQAELLDPAIKGTINVLKAAKNHNVRRVVVTSSISAMIPSSNSLADAGEGCWIDEDYCRQNGFLYSVSKALAEKAAWQFAEENGVDVVVLNPGVVAGPILTPAINTSMTLILHVLQGKDFPEELFEALVHVKDVALAHILLYENTSAAGRH...

XP_057782582.1
MKKNTFSTRHSHMVMSKEGEVVCVTGASGFIGSWLVHFLLHRGYAVRATVKNLGDERETKHLEAMEGADSRLRLFQIDLLDYDSIVAAVSGAAGVFHLASPCIIDQIEDPQAELLDPAIKGTINVLKAAKNHNVRRVVVTSSISAMIPSSNSLADAGEGCWIDEDYCRQNGFLYSVSKALAEKAAWQFAEENGVDVVVLNPGVVAGPILTPAINTSMTLILHVLQGKDFPEELFEALVHVKDVALAHILLYENTSAAGRH...

上下游序列下载

upstream/downstream 最大各 10000 bp。负链基因会自动反向互补，使最终 FASTA 为转录方向 5′→3′。

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