Gene Card 基因详情

支持统一新 ID、NCBI Gene ID、GeneID、locus_tag、Transcript ID、Protein ID，以及已人工核对的文献基因名查询。页面会先解析到丹参统一基因，再整合坐标、序列、注释、亚细胞定位、EMS 突变和下载入口。

当前解析结果

`SmilChr08G001142`

染色体: Chr08 坐标: 9006989-9012934 链方向: + 类型: protein_coding

基本信息

统一新 Gene ID	`SmilChr08G001142`
名称	SmilChr08G001142
描述	calcium-transporting ATPase 4, endoplasmic reticulum-type-like
染色体 / SeqID	Chr08 / NC_080394.1
坐标与链方向	9006989 - 9012934 / `+`

ID 对照

NCBI Gene ID	`LOC131000727`
GeneID	`131000727`
locus_tag	`-`
NCBI Name	`LOC131000727`
原始查询	`SmilChr08G001142`

查看完整 ID 对照表

功能注释

来源	GFF basic annotation; NCBI GO GAF; Pfam-A/HMMER; Arabidopsis/Rice homolog
描述	calcium-transporting ATPase 4, endoplasmic reticulum-type-like
产物	calcium-transporting ATPase 4%2C endoplasmic reticulum-type-like
Arabidopsis	`AT1G07670` (ECA4) endomembrane-type CA-ATPase 4 [Source:NCBI gene (formerly Entrezgene);Acc:837280] identity=79.7; qcov=1; evalue=0; confidence=high
Rice	`Os03g0281600` (OsECA1) - identity=74.4; qcov=1; evalue=0; confidence=high
GO	GO:0005388 (P-type calcium transporter activity); GO:0005524 (ATP binding); GO:0006874 (intracellular calcium ion homeostasis); GO:0016020 (membrane); GO:0016887 (ATP hydrolysis activity); GO:0070588 (calcium ion transmembrane transport)
KEGG	-
Pfam	PF00122 (E1-E2_ATPase); PF00689 (Cation_ATPase_C); PF00690 (Cation_ATPase_N); PF00702 (Hydrolase); PF13246 (Cation_ATPase)
InterPro	-
eggNOG	-
NR	GeneID:131000727

打开注释模块

亚细胞定位 Top 5

Rank	定位位置	中文	Score	Protein ID
1	Endoplasmic reticulum	内质网	0.60000	`XP_057782751.1`
2	Endoplasmic reticulum membrane	内质网膜	0.40000	`XP_057782751.1`
3	Vacuole membrane	液泡膜	0.40000	`XP_057782751.1`
4	Cell membrane	细胞膜	0.20000	`XP_057782751.1`
5	Vacuole	液泡	0.20000	`XP_057782751.1`

进入亚细胞定位查询

EMS 诱变突变

下表显示该基因在丹参 EMS 材料中的前 12 个候选突变；完整结果可进入 EMS 突变库继续筛选或下载。

位置	REF	ALT	类型	影响	携带材料数	材料
`Chr8:9008001`	`G`	`A`	EMS_canonical_SNV	CDS_variant	2	D10,D11
`Chr8:9008111`	`C`	`T`	EMS_canonical_SNV	CDS_variant	1	C19
`Chr8:9008483`	`C`	`T`	EMS_canonical_SNV	CDS_variant	3	B136,C16,C62
`Chr8:9008603`	`G`	`A`	EMS_canonical_SNV	CDS_variant	4	B136,B70,C16,C62
`Chr8:9008663`	`C`	`T`	EMS_canonical_SNV	CDS_variant	3	A18,B108,C28
`Chr8:9008782`	`C`	`T`	EMS_canonical_SNV	CDS_variant	1	D11
`Chr8:9008787`	`G`	`A`	EMS_canonical_SNV	CDS_variant	3	A18,B108,C28
`Chr8:9009459`	`TCC`	`T`	2bp_deletion	frameshift_variant	20	A21,A23,A5,A7,B109,B12,B124,B135,B16,B24,B32,B35,B5,B57,B67,B97,C11,C53,C79,C8
`Chr8:9009488`	`G`	`A`	EMS_canonical_SNV	CDS_variant	3	B28,B30,D3
`Chr8:9009494`	`T`	`TA`	1bp_insertion	frameshift_variant	51	A10,A13,A2,A21,A23,A7,B107,B114,B124,B138,B16,B17,B19,B20,B28,B29,B30,B32,B38,B39,B49,B5,B52,B54,B57,B61,B62,B65,B70,B78,B82,B86,B87,B89,B96,B97,B98,B99,C27,C30,C33,C4,C54,C61,C65,C7,C71,C72,C8,D3,D4
`Chr8:9009513`	`G`	`GAT`	2bp_insertion	frameshift_variant	1	C45
`Chr8:9009513`	`G`	`GAT`	2bp_insertion	CDS_variant	1	C45

进入 EMS 突变库

预测功能结构域

结构域结果来自 Pfam-A HMM 数据库和 HMMER hmmscan；位置为对应蛋白序列上的氨基酸坐标。

XP_057782751.1

1069 aa

534

1069

Cation_ATPase_N

E1-E2_ATPase

Cation_ATPase

Hydrolase

Cation_ATPase_C

PF00690 Cation_ATPase_N 28-95 aa PF00122 E1-E2_ATPase 148-262 aa PF13246 Cation_ATPase 438-641 aa PF00702 Hydrolase 630-752 aa PF00689 Cation_ATPase_C 824-1048 aa

Protein ID	来源	结构域编号	结构域名称	类型	起始 aa	终止 aa	E-value	Score	说明
`XP_057782751.1`	Pfam	`PF00690`	Cation_ATPase_N	Domain	28	95	9.5e-19	67.5	Cation transporter/ATPase, N-terminus
`XP_057782751.1`	Pfam	`PF00122`	E1-E2_ATPase	Domain	148	262	6.9e-25	87.5	P-type ATPase actuator domain
`XP_057782751.1`	Pfam	`PF13246`	Cation_ATPase	Family	438	641	3.5e-37	128.7	P-type ATPase, cytoplasmic domain N
`XP_057782751.1`	Pfam	`PF00702`	Hydrolase	Domain	630	752	6.8e-18	66.5	haloacid dehalogenase-like hydrolase
`XP_057782751.1`	Pfam	`PF00689`	Cation_ATPase_C	Family	824	1048	6.1e-49	166.9	Cation transporting ATPase, C-terminus

cDNA / CDS / Protein 序列

下载基因组 DNA（仅基因区域）

每个公开基因均提供参考注释对应的转录本序列；蛋白编码基因另提供 CDS 和蛋白序列。非编码 RNA 不适用 CDS 或蛋白下载。真实 accession 的版本后缀予以保留。

cDNA

1 records

下载 cDNA FASTA

XM_057926768.1
AAATAAGATTAGAAAAAAGAAATACTATAAAAAATAGGCGATGTTGTTGGGGGAGAAGGTGCGAAGAAGCTAATGAGGGCTATTGAAAGCTTCAGTGTTTGTACCTTGTTGTAAAACAAGGGTAGCACGCATCTCTGCCTTTCTCTTTCCTCCCCTTCTCTCCCTCTCTCTCACACACACTTGAGTAAAATCGCTCCCCATAAATACCAAACGCATCCCACCATTTCCAGAGTTTCTCGATACGCAGAAACTTCAAACCC...

CDS

1 records

下载 CDS FASTA

LOC131000727
ATGGGGAAAGGAGGGCAAAATTACGGTAAGAGTGAGAAGTTGGGTGATGATAAGGAGCGGAAAGGGGATTATTACGCGGCGTGGTCTAAAGATGTAAGAGAGTGTGAGGAGAAGTTTCAAGTAAGGAAGGGGCATGGATTGTCGGGTGATGATGTCGAAAAGAGGAGGCAGATCTACGGTCTTAATGAGCTGGAGAAACACGAGGGGCCTTCAATTATTAGGTTGATTCTGGATCAGTTCAATGACACGTTAGTTAGAAT...

Protein

1 records

下载 Protein FASTA

XP_057782751.1
MGKGGQNYGKSEKLGDDKERKGDYYAAWSKDVRECEEKFQVRKGHGLSGDDVEKRRQIYGLNELEKHEGPSIIRLILDQFNDTLVRILLVAAVVSFVLAWYDGDEGGEMEITAFVEPLVIFLILIVNAIVGVWQENNAEKALDALKEIQSEHATVIREGKKISSLPAKELVPGDIVELRVGDKVPADMRVLSLISSTLRVEQGSLTGESEAVSKTTKAVAEDVDIQGKKCMVFAGTTVVNGNCICLVTQIGMNTEIGKVH...

上下游序列下载

upstream/downstream 最大各 10000 bp。负链基因会自动反向互补，使最终 FASTA 为转录方向 5′→3′。

下载 upstream 下载 downstream 下载 upstream + gene + downstream

JBrowse

跳转到基因组浏览器