Gene Card 基因详情

支持统一新 ID、NCBI Gene ID、GeneID、locus_tag、Transcript ID、Protein ID，以及已人工核对的文献基因名查询。页面会先解析到丹参统一基因，再整合坐标、序列、注释、亚细胞定位、EMS 突变和下载入口。

当前解析结果

`SmilChr08G001147`

染色体: Chr08 坐标: 9044125-9053091 链方向: - 类型: protein_coding

基本信息

统一新 Gene ID	`SmilChr08G001147`
名称	SmilChr08G001147
描述	E3 UFM1-protein ligase 1 homolog
染色体 / SeqID	Chr08 / NC_080394.1
坐标与链方向	9044125 - 9053091 / `-`

ID 对照

NCBI Gene ID	`LOC131000731`
GeneID	`131000731`
locus_tag	`-`
NCBI Name	`LOC131000731`
原始查询	`SmilChr08G001147`

查看完整 ID 对照表

功能注释

来源	GFF basic annotation; NCBI GO GAF; Pfam-A/HMMER; Arabidopsis/Rice homolog
描述	E3 UFM1-protein ligase 1 homolog
产物	E3 UFM1-protein ligase 1 homolog
Arabidopsis	`AT3G46220` (AT3G46220) E3 UFM1-protein ligase-like protein [Source:NCBI gene (formerly Entrezgene);Acc:823767] identity=59.6; qcov=1; evalue=0; confidence=high
Rice	`Os05g0117600` - identity=56.9; qcov=1; evalue=0; confidence=high
GO	GO:0005789 (endoplasmic reticulum membrane); GO:0032434 (regulation of proteasomal ubiquitin-dependent protein catabolic process); GO:0034976 (response to endoplasmic reticulum stress); GO:0061666 (UFM1 ligase activity); GO:1990592 (protein K69-linked ufmylation)
KEGG	-
Pfam	PF09743 (E3_UFM1_ligase); PF23659 (UFL1); PF25041 (UFL1_C); PF25870 (WHD_UFL1_5th)
InterPro	-
eggNOG	-
NR	GeneID:131000731

打开注释模块

亚细胞定位 Top 5

Rank	定位位置	中文	Score	Protein ID
1	Nucleus	细胞核	1.00000	`XP_057782761.1`
2	Cytoplasm	细胞质	0.40000	`XP_057782761.1`
3	Chromosome	染色体	0.00000	`XP_057782761.1`
4	Centromere	着丝粒	0.00000	`XP_057782761.1`
5	Chromatin	染色质	0.00000	`XP_057782761.1`

进入亚细胞定位查询

EMS 诱变突变

下表显示该基因在丹参 EMS 材料中的前 12 个候选突变；完整结果可进入 EMS 突变库继续筛选或下载。

位置	REF	ALT	类型	影响	携带材料数	材料
`Chr8:9044329`	`TCG`	`T`	2bp_deletion	frameshift_variant	1	C26
`Chr8:9044329`	`TCG`	`T`	2bp_deletion	CDS_variant	1	C26
`Chr8:9044966`	`G`	`A`	EMS_canonical_SNV	CDS_variant	3	B55,B62,C2
`Chr8:9045157`	`G`	`A`	EMS_canonical_SNV	CDS_variant	1	B118
`Chr8:9045817`	`G`	`A`	EMS_canonical_SNV	CDS_variant	3	B15,C19,C78
`Chr8:9047054`	`C`	`T`	EMS_canonical_SNV	CDS_variant	1	D11
`Chr8:9047167`	`C`	`T`	EMS_canonical_SNV	CDS_variant	1	D8
`Chr8:9049145`	`G`	`A`	EMS_canonical_SNV	CDS_variant	2	B66,B8
`Chr8:9051686`	`C`	`T`	EMS_canonical_SNV	CDS_variant	1	B86
`Chr8:9051998`	`G`	`A`	EMS_canonical_SNV	CDS_variant	2	B15,C78
`Chr8:9052040`	`C`	`T`	EMS_canonical_SNV	CDS_variant	3	B100,B56,B96
`Chr8:9052393`	`C`	`T`	EMS_canonical_SNV	CDS_variant	3	B15,C19,C78

进入 EMS 突变库

预测功能结构域

结构域结果来自 Pfam-A HMM 数据库和 HMMER hmmscan；位置为对应蛋白序列上的氨基酸坐标。

XP_057782761.1

813 aa

406

813

E3_UFM1_ligase

WHD_UFL1_5th

UFL1

UFL1_C

PF09743 E3_UFM1_ligase 4-288 aa PF25870 WHD_UFL1_5th 305-364 aa PF23659 UFL1 561-691 aa PF25041 UFL1_C 696-809 aa

XP_057782762.1

813 aa

406

813

E3_UFM1_ligase

WHD_UFL1_5th

UFL1

UFL1_C

PF09743 E3_UFM1_ligase 4-288 aa PF25870 WHD_UFL1_5th 305-364 aa PF23659 UFL1 561-691 aa PF25041 UFL1_C 696-809 aa

Protein ID	来源	结构域编号	结构域名称	类型	起始 aa	终止 aa	E-value	Score	说明
`XP_057782761.1`	Pfam	`PF09743`	E3_UFM1_ligase	Family	4	288	5.9e-95	318.7	E3 UFM1-protein ligase 1
`XP_057782761.1`	Pfam	`PF25870`	WHD_UFL1_5th	Domain	305	364	7.4e-08	32.9	Winged helix-turn-helix domain 5 in UFL1 protein
`XP_057782761.1`	Pfam	`PF23659`	UFL1	Domain	561	691	1.1e-33	116.9	E3 UFM1-protein ligase 1-like domain
`XP_057782761.1`	Pfam	`PF25041`	UFL1_C	Domain	696	809	1.3e-30	106.2	E3 UFM1-protein ligase 1 C-terminal domain
`XP_057782762.1`	Pfam	`PF09743`	E3_UFM1_ligase	Family	4	288	5.9e-95	318.7	E3 UFM1-protein ligase 1
`XP_057782762.1`	Pfam	`PF25870`	WHD_UFL1_5th	Domain	305	364	7.4e-08	32.9	Winged helix-turn-helix domain 5 in UFL1 protein
`XP_057782762.1`	Pfam	`PF23659`	UFL1	Domain	561	691	1.1e-33	116.9	E3 UFM1-protein ligase 1-like domain
`XP_057782762.1`	Pfam	`PF25041`	UFL1_C	Domain	696	809	1.3e-30	106.2	E3 UFM1-protein ligase 1 C-terminal domain

cDNA / CDS / Protein 序列

下载基因组 DNA（仅基因区域）

每个公开基因均提供参考注释对应的转录本序列；蛋白编码基因另提供 CDS 和蛋白序列。非编码 RNA 不适用 CDS 或蛋白下载。真实 accession 的版本后缀予以保留。

cDNA

2 records

下载 cDNA FASTA

XM_057926778.1
ATTTGTTATTCGTAAAAGAAGAAAAGCAAAAAAAATACACTCCATTTAGTTGCCACTAAATCTAATTAAGAAAAAGGGCCTACAGTAAAACTGAACTGAACAGCACATTTCCTCCGTTATACCCCAACGATCACCACCGGAAGTCAAGACTCACACACCTCCGCCGCCGCTGCCATGGATGAGGAACTTCTGGAACTGCAGAGGCAATTCGAGTTCGCACAGCAGGCGAAATCCAGCATCCGTTTATCCGAACGAAACGT...

XM_057926779.1
AAGAAAAGCAAAAAAAATACACTCCATTTAGTTGCCACTAAATCTAATTAAGAAAAAGGGCCTACAGTAAAACTGAACTGAACAGCACATTTCCTCCGTTATACCCCAACGATCACCACCGGAAGTCAAGACTCACACACCTCCGCCGCCGCTGCCATGGATGAGGAACTTCTGGAACTGCAGAGGCAATTCGAGTTCGCACAGCAGGCGAAATCCAGCATCCGTTTATCCGAACGAAACGTCGTCGAATTGGTTCAGAA...

CDS

2 records

下载 CDS FASTA

LOC131000731
ATGGATGAGGAACTTCTGGAACTGCAGAGGCAATTCGAGTTCGCACAGCAGGCGAAATCCAGCATCCGTTTATCCGAACGAAACGTCGTCGAATTGGTTCAGAAACTCCAGGAACTCGAAATCATCGACTTCGAACTTCTCCACACCTCCTCCGGCAAAGAATACATCACTCAGGAGCAATTGATTAGTGAAATTGTTTCTGAAATAAATAAGAGAGGTCGAGTATCCTTGATTGATTTGGCGGATACCATAGGGGTAGA...

Protein

2 records

下载 Protein FASTA

XP_057782761.1
MDEELLELQRQFEFAQQAKSSIRLSERNVVELVQKLQELEIIDFELLHTSSGKEYITQEQLISEIVSEINKRGRVSLIDLADTIGVDLYHVEKQSQHVVSNDSSLMLINGEIVSSSYWDTVSEEINERLQECSQISLAEIAAQLQVGSELIVSVLEPRIGTLIKGRLEGGQLYTPAYVARVNAMVRGAARGIAVPRNMSAWWSSLQVLLQDMDGFSGVAVESGFFQSLFNGLVKGGEILGSLRAGVHWTPSVFAMAQKEC...

XP_057782762.1
MDEELLELQRQFEFAQQAKSSIRLSERNVVELVQKLQELEIIDFELLHTSSGKEYITQEQLISEIVSEINKRGRVSLIDLADTIGVDLYHVEKQSQHVVSNDSSLMLINGEIVSSSYWDTVSEEINERLQECSQISLAEIAAQLQVGSELIVSVLEPRIGTLIKGRLEGGQLYTPAYVARVNAMVRGAARGIAVPRNMSAWWSSLQVLLQDMDGFSGVAVESGFFQSLFNGLVKGGEILGSLRAGVHWTPSVFAMAQKEC...

上下游序列下载

upstream/downstream 最大各 10000 bp。负链基因会自动反向互补，使最终 FASTA 为转录方向 5′→3′。

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