Gene Card 基因详情

支持统一新 ID、NCBI Gene ID、GeneID、locus_tag、Transcript ID、Protein ID，以及已人工核对的文献基因名查询。页面会先解析到丹参统一基因，再整合坐标、序列、注释、亚细胞定位、EMS 突变和下载入口。

当前解析结果

`SmilChr08G001411`

染色体: Chr08 坐标: 11303430-11308886 链方向: + 类型: protein_coding

基本信息

统一新 Gene ID	`SmilChr08G001411`
名称	SmilChr08G001411
描述	DNA replication licensing factor MCM4
染色体 / SeqID	Chr08 / NC_080394.1
坐标与链方向	11303430 - 11308886 / `+`

ID 对照

NCBI Gene ID	`LOC131000958`
GeneID	`131000958`
locus_tag	`-`
NCBI Name	`LOC131000958`
原始查询	`SmilChr08G001411`

查看完整 ID 对照表

功能注释

来源	GFF basic annotation; NCBI GO GAF; KEGG smil; Pfam-A/HMMER; Arabidopsis/Rice homolog
描述	DNA replication licensing factor MCM4
产物	DNA replication licensing factor MCM4
Arabidopsis	`AT2G16440` (MCM4) Minichromosome maintenance (MCM2/3/5) family protein [Source:NCBI gene (formerly Entrezgene);Acc:816142] identity=72.7; qcov=1.02; evalue=0; confidence=high
Rice	`Os01g0544450` (OsMCM4) - identity=75.2; qcov=0.952; evalue=0; confidence=high
GO	GO:0000727 (double-strand break repair via break-induced replication); GO:0003697 (single-stranded DNA binding); GO:0005524 (ATP binding); GO:0005634 (nucleus); GO:0006260 (DNA replication); GO:0006268 (GO:0006268); GO:0006271 (DNA strand elongation involved in DNA replication); GO:0016887 (ATP hydrolysis activity); GO:0017116 (single-stranded DNA helicase activity); GO:0042555 (MCM complex); GO:1902975 (mitotic DNA replication initiation)
KEGG	smil03030 (DNA replication - Salvia miltiorrhiza (redroot sage))
Pfam	PF00493 (MCM); PF01078 (Mg_chelatase); PF07728 (AAA_5); PF14551 (MCM_N); PF17207 (MCM_OB); PF17855 (MCM_lid); PF21128 (WHD_MCM4)
InterPro	-
eggNOG	-
NR	GeneID:131000958

打开注释模块

亚细胞定位 Top 5

Rank	定位位置	中文	Score	Protein ID
1	Nucleus	细胞核	1.00000	`XP_057783093.1`
2	Chromosome	染色体	0.80000	`XP_057783093.1`
3	Nucleoplasm	核质	0.80000	`XP_057783093.1`
4	Centromere	着丝粒	0.00000	`XP_057783093.1`
5	Chromatin	染色质	0.00000	`XP_057783093.1`

进入亚细胞定位查询

EMS 诱变突变

下表显示该基因在丹参 EMS 材料中的前 12 个候选突变；完整结果可进入 EMS 突变库继续筛选或下载。

位置	REF	ALT	类型	影响	携带材料数	材料
`Chr8:11305980`	`C`	`T`	EMS_canonical_SNV	CDS_variant	1	B112
`Chr8:11307081`	`C`	`T`	EMS_canonical_SNV	CDS_variant	2	A2,B52
`Chr8:11307868`	`G`	`A`	EMS_canonical_SNV	CDS_variant	2	B104,B37
`Chr8:11308032`	`G`	`A`	EMS_canonical_SNV	CDS_variant	1	B83
`Chr8:11308334`	`C`	`T`	EMS_canonical_SNV	CDS_variant	2	B83,C67
`Chr8:11308683`	`C`	`T`	EMS_canonical_SNV	CDS_variant	1	D10

进入 EMS 突变库

预测功能结构域

结构域结果来自 Pfam-A HMM 数据库和 HMMER hmmscan；位置为对应蛋白序列上的氨基酸坐标。

XP_057783093.1

834 aa

417

834

MCM_N

MCM_OB

MCM

AAA_5

Mg_chelatase

MCM_lid

WHD_MCM4

PF14551 MCM_N 128-216 aa PF17207 MCM_OB 223-352 aa PF00493 MCM 411-633 aa PF07728 AAA_5 468-584 aa PF01078 Mg_chelatase 518-583 aa PF17855 MCM_lid 649-735 aa PF21128 WHD_MCM4 759-834 aa

Protein ID	来源	结构域编号	结构域名称	类型	起始 aa	终止 aa	E-value	Score	说明
`XP_057783093.1`	Pfam	`PF14551`	MCM_N	Domain	128	216	2.7e-15	57.3	MCM N-terminal domain
`XP_057783093.1`	Pfam	`PF17207`	MCM_OB	Domain	223	352	1.4e-39	135.5	MCM OB domain
`XP_057783093.1`	Pfam	`PF00493`	MCM	Domain	411	633	7.4e-101	336.7	MCM P-loop domain
`XP_057783093.1`	Pfam	`PF07728`	AAA_5	Domain	468	584	4.2e-07	30.8	AAA domain (dynein-related subfamily)
`XP_057783093.1`	Pfam	`PF01078`	Mg_chelatase	Domain	518	583	1.6e-07	31.7	Magnesium chelatase, subunit ChlI
`XP_057783093.1`	Pfam	`PF17855`	MCM_lid	Domain	649	735	1.7e-27	96.4	MCM AAA-lid domain
`XP_057783093.1`	Pfam	`PF21128`	WHD_MCM4	Domain	759	834	6.3e-11	42.9	MCM4, winged helix domain

cDNA / CDS / Protein 序列

下载基因组 DNA（仅基因区域）

每个公开基因均提供参考注释对应的转录本序列；蛋白编码基因另提供 CDS 和蛋白序列。非编码 RNA 不适用 CDS 或蛋白下载。真实 accession 的版本后缀予以保留。

cDNA

1 records

下载 cDNA FASTA

XM_057927110.1
TTCCCGCCAATTTGCTGCAGACAATTAGGCACTTTCCCTCGCTTCCCCTTTCGCCCTAACCGCTCTGCTCTCTCTCTCACCCAGTATCACCATTCCAGACACTCGTTCGCACGCTGAAGATCATGGCTTCCGATTCTTCTCCTGTCAACACGCACGACGGTCCGTCGTCTCCGGATGCGTGGCCGACGAGCCCAGTCAGCAACACAGTATCATCTCCTGGAGAGCGCTCGCGCCGGAAACGTGGCCGTCATTCCAGCTAC...

CDS

1 records

下载 CDS FASTA

LOC131000958
ATGGCTTCCGATTCTTCTCCTGTCAACACGCACGACGGTCCGTCGTCTCCGGATGCGTGGCCGACGAGCCCAGTCAGCAACACAGTATCATCTCCTGGAGAGCGCTCGCGCCGGAAACGTGGCCGTCATTCCAGCTACGCTACGCCGTCACCGATGCCGTCAGGTTCGCGTGTCAGAACACCCGAGGCAACTCCAACGCCCTCTAGTAACGCTCGACGTCGTGGCCGAGGTAGGAGGCAGTCGACCACCCCTACTGCTGG...

Protein

1 records

下载 Protein FASTA

XP_057783093.1
MASDSSPVNTHDGPSSPDAWPTSPVSNTVSSPGERSRRKRGRHSSYATPSPMPSGSRVRTPEATPTPSSNARRRGRGRRQSTTPTAGATPTSNDDVPPSSDAGEGNEDEPPVVYVWGTNISVQDVNAAILRFLRHFREDPQQIEGKYMRMINHVIEMEGDSLDVDAQDVYDYDSDLYTKMVRYPLEVLAIFDMVLMDMVGRINPLFEKHIQARIFNLRSSTSMRNLNPSDVEKMVSLKGMIIRCSSIIPEIREAVFRCLV...

上下游序列下载

upstream/downstream 最大各 10000 bp。负链基因会自动反向互补，使最终 FASTA 为转录方向 5′→3′。

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