Gene Card 基因详情

支持统一新 ID、NCBI Gene ID、GeneID、locus_tag、Transcript ID、Protein ID，以及已人工核对的文献基因名查询。页面会先解析到丹参统一基因，再整合坐标、序列、注释、亚细胞定位、EMS 突变和下载入口。

当前解析结果

`SmilChr08G002171`

染色体: Chr08 坐标: 19630388-19634746 链方向: - 类型: protein_coding

基本信息

统一新 Gene ID	`SmilChr08G002171`
名称	SmilChr08G002171
描述	mannose-6-phosphate isomerase 1-like
染色体 / SeqID	Chr08 / NC_080394.1
坐标与链方向	19630388 - 19634746 / `-`

ID 对照

NCBI Gene ID	`LOC131001590`
GeneID	`131001590`
locus_tag	`-`
NCBI Name	`LOC131001590`
原始查询	`SmilChr08G002171`

查看完整 ID 对照表

功能注释

来源	GFF basic annotation; NCBI GO GAF; KEGG smil; Pfam-A/HMMER; Arabidopsis/Rice homolog
描述	mannose-6-phosphate isomerase 1-like
产物	mannose-6-phosphate isomerase 1-like
Arabidopsis	`AT1G67070` (DIN9) Mannose-6-phosphate isomerase, type I [Source:NCBI gene (formerly Entrezgene);Acc:843027] identity=58.6; qcov=0.96; evalue=7.36e-180; confidence=high
Rice	`Os01g0127900` - identity=55.3; qcov=0.969; evalue=1.78e-167; confidence=high
GO	GO:0004476 (mannose-6-phosphate isomerase activity); GO:0005829 (cytosol); GO:0005975 (carbohydrate metabolic process); GO:0008270 (zinc ion binding); GO:0009298 (GDP-mannose biosynthetic process)
KEGG	smil00051 (Fructose and mannose metabolism - Salvia miltiorrhiza (redroot sage)); smil00520 (Amino sugar and nucleotide sugar metabolism - Salvia miltiorrhiza (redroot sage)); smil01100 (Metabolic pathways - Salvia miltiorrhiza (redroot sage)); smil01110 (Biosynthesis of secondary metabolites - Salvia miltiorrhiza (redroot sage)); smil01240 (Biosynthesis of cofactors - Salvia miltiorrhiza (redroot sage)); smil01250 (Biosynthesis of nucleotide sugars - Salvia miltiorrhiza (redroot sage))
Pfam	PF20511 (PMI_typeI_cat); PF20512 (PMI_typeI_hel)
InterPro	-
eggNOG	-
NR	GeneID:131001590

打开注释模块

亚细胞定位 Top 5

Rank	定位位置	中文	Score	Protein ID
1	Cytosol	细胞质基质	1.00000	`XP_057784070.1`
2	Cytoplasm	细胞质	0.80000	`XP_057784070.1`
3	Nucleus	细胞核	0.00000	`XP_057784070.1`
4	Chromosome	染色体	0.00000	`XP_057784070.1`
5	Centromere	着丝粒	0.00000	`XP_057784070.1`

进入亚细胞定位查询

EMS 诱变突变

下表显示该基因在丹参 EMS 材料中的前 12 个候选突变；完整结果可进入 EMS 突变库继续筛选或下载。

位置	REF	ALT	类型	影响	携带材料数	材料
`Chr8:19630756`	`C`	`T`	EMS_canonical_SNV	CDS_variant	1	B35
`Chr8:19630929`	`C`	`T`	EMS_canonical_SNV	CDS_variant	4	B1,B91,C82,D10
`Chr8:19630930`	`G`	`A`	EMS_canonical_SNV	CDS_variant	4	B38,B39,B60,B76
`Chr8:19630936`	`G`	`A`	EMS_canonical_SNV	CDS_variant	1	A18
`Chr8:19632144`	`TTG`	`T`	2bp_deletion	frameshift_variant	1	C72
`Chr8:19632144`	`TTG`	`T`	2bp_deletion	CDS_variant	1	C72
`Chr8:19632205`	`G`	`A`	EMS_canonical_SNV	CDS_variant	4	B38,B39,B60,B76
`Chr8:19632221`	`C`	`T`	EMS_canonical_SNV	CDS_variant	1	A3
`Chr8:19632234`	`C`	`T`	EMS_canonical_SNV	CDS_variant	2	B104,D11
`Chr8:19632251`	`C`	`T`	EMS_canonical_SNV	CDS_variant	3	B104,B66,B8

进入 EMS 突变库

预测功能结构域

结构域结果来自 Pfam-A HMM 数据库和 HMMER hmmscan；位置为对应蛋白序列上的氨基酸坐标。

XP_057784070.1

450 aa

225

450

PMI_typeI_cat

PMI_typeI_hel

PF20511 PMI_typeI_cat 8-173 aa PF20512 PMI_typeI_hel 204-277 aa

Protein ID	来源	结构域编号	结构域名称	类型	起始 aa	终止 aa	E-value	Score	说明
`XP_057784070.1`	Pfam	`PF20511`	PMI_typeI_cat	Domain	8	173	4.5e-44	150.8	Phosphomannose isomerase type I, catalytic domain
`XP_057784070.1`	Pfam	`PF20512`	PMI_typeI_hel	Domain	204	277	2.3e-12	47.9	Phosphomannose isomerase type I, helical insertion domain

cDNA / CDS / Protein 序列

下载基因组 DNA（仅基因区域）

每个公开基因均提供参考注释对应的转录本序列；蛋白编码基因另提供 CDS 和蛋白序列。非编码 RNA 不适用 CDS 或蛋白下载。真实 accession 的版本后缀予以保留。

cDNA

1 records

下载 cDNA FASTA

XM_057928087.1
CATAAAACCTCTATATTATTAGCTAAAGAGTTTCTATATATATGAAGAAAAAAAAACATGAAAAAGACCTTATCCTATAAATTAATTTAAAAATATTGACTCAAGCAAGTTGGGTTGGCATGCAAGTAACCAGATGGGTCCCAAGAATTCTGACGTAGCCTTGGTTTGTGGAAACTGTCAAACGCCGTTACTGCTAAAACTTTGTCAACTCGCTGACGCTTTGCGCCACCGACCCACCGAGTCATCACCCGCCGTTTCCA...

CDS

1 records

下载 CDS FASTA

LOC131001590
ATGGGGGCGGAAATTCCTGGAATTGTCAGGCTCAAGTGCTCTGTTAAGAACTATGACTGGGGAAAGCTCGGGGAAGAATCGGCGGTGGCGCGGCTGTATGCGAAGAACAGTGGGGAGGAGGTGGACGGAGGAGAGCCCTATGCTGAGTTCTGGATAGGAACTCACGAGTCAGGGCCGTCCTACGTCGTTGCAGCGGCGGAGGCGACTGGCGGAGTGAGGAATAGTGGTGTGGAGGGGAGGGACGGCTGTGATCGTAAGCA...

Protein

1 records

下载 Protein FASTA

XP_057784070.1
MGAEIPGIVRLKCSVKNYDWGKLGEESAVARLYAKNSGEEVDGGEPYAEFWIGTHESGPSYVVAAAEATGGVRNSGVEGRDGCDRKQGDFVSLKDWIERNPSVLGDKVLQKWGPTLPFLFKVLSVEKALSIQAHPDKDLAPILHKQQPGVYKDGNHKPEMALALTEFEALCGFVGLEELKTVVRSVPEMTEVVGNSCAVQVLNTSEDDGEKKLKEVLQSLFTGLMLASKTVISEIIPKLIRRLNLKGQVMELTDKEELVL...

上下游序列下载

upstream/downstream 最大各 10000 bp。负链基因会自动反向互补，使最终 FASTA 为转录方向 5′→3′。

下载 upstream 下载 downstream 下载 upstream + gene + downstream

JBrowse

跳转到基因组浏览器