Gene Card 基因详情

支持统一新 ID、NCBI Gene ID、GeneID、locus_tag、Transcript ID、Protein ID，以及已人工核对的文献基因名查询。页面会先解析到丹参统一基因，再整合坐标、序列、注释、亚细胞定位、EMS 突变和下载入口。

当前解析结果

`SmilChr08G002263`

染色体: Chr08 坐标: 20879254-20884012 链方向: + 类型: protein_coding

基本信息

统一新 Gene ID	`SmilChr08G002263`
名称	SmilChr08G002263
描述	COMPASS-like H3K4 histone methylase component WDR5A
染色体 / SeqID	Chr08 / NC_080394.1
坐标与链方向	20879254 - 20884012 / `+`

ID 对照

NCBI Gene ID	`LOC131001786`
GeneID	`131001786`
locus_tag	`-`
NCBI Name	`LOC131001786`
原始查询	`SmilChr08G002263`

查看完整 ID 对照表

功能注释

来源	GFF basic annotation; NCBI GO GAF; KEGG smil; Pfam-A/HMMER; Arabidopsis/Rice homolog
描述	COMPASS-like H3K4 histone methylase component WDR5A
产物	COMPASS-like H3K4 histone methylase component WDR5A
Arabidopsis	`AT3G49660` (WDR5a) Transducin/WD40 repeat-like superfamily protein [Source:NCBI gene (formerly Entrezgene);Acc:824128] identity=71.8; qcov=1.01; evalue=4.53e-176; confidence=high
Rice	`Os03g0725400` (OsWDR5a) - identity=70.4; qcov=0.987; evalue=3.65e-168; confidence=high
GO	GO:0042393 (histone binding); GO:0048188 (Set1C/COMPASS complex); GO:0051568 (GO:0051568)
KEGG	smil03083 (Polycomb repressive complex - Salvia miltiorrhiza (redroot sage))
Pfam	PF00400 (WD40); PF12894 (ANAPC4_WD40); PF23342 (WDR90_beta-prop_4th); PF23381 (Beta-prop_IFT122_1st); PF25175 (Beta-prop_WDR5)
InterPro	-
eggNOG	-
NR	GeneID:131001786

打开注释模块

亚细胞定位 Top 5

Rank	定位位置	中文	Score	Protein ID
1	Nucleus	细胞核	1.00000	`XP_057784361.1`
2	Chromosome	染色体	0.20000	`XP_057784361.1`
3	Centromere	着丝粒	0.00000	`XP_057784361.1`
4	Chromatin	染色质	0.00000	`XP_057784361.1`
5	Telomere	端粒	0.00000	`XP_057784361.1`

进入亚细胞定位查询

EMS 诱变突变

下表显示该基因在丹参 EMS 材料中的前 12 个候选突变；完整结果可进入 EMS 突变库继续筛选或下载。

位置	REF	ALT	类型	影响	携带材料数	材料
`Chr8:20879439`	`C`	`T`	EMS_canonical_SNV	CDS_variant	4	B10,B112,B9,C3
`Chr8:20879600`	`AC`	`A`	1bp_deletion	frameshift_variant	1	B117
`Chr8:20879600`	`AC`	`A`	1bp_deletion	CDS_variant	1	B117
`Chr8:20879730`	`C`	`T`	EMS_canonical_SNV	CDS_variant	2	B111,B51
`Chr8:20883781`	`C`	`T`	EMS_canonical_SNV	CDS_variant	2	B36,C83

进入 EMS 突变库

预测功能结构域

结构域结果来自 Pfam-A HMM 数据库和 HMMER hmmscan；位置为对应蛋白序列上的氨基酸坐标。

XP_057784361.1

315 aa

158

315

WD40

Beta-prop_WDR5

WD40

ANAPC4_WD40

WDR90_beta-prop_4th

Beta-prop_IFT122_1st

WD40

ANAPC4_WD40

WD40

PF00400 WD40 16-50 aa PF25175 Beta-prop_WDR5 19-311 aa PF00400 WD40 59-95 aa PF12894 ANAPC4_WD40 66-117 aa PF23342 WDR90_beta-prop_4th 70-198 aa PF23381 Beta-prop_IFT122_1st 70-241 aa PF00400 WD40 99-137 aa PF12894 ANAPC4_WD40 108-160 aa PF00400 WD40 141-179 aa PF00400 WD40 184-222 aa PF00400 WD40 226-266 aa PF00400 WD40 272-311 aa

Protein ID	来源	结构域编号	结构域名称	类型	起始 aa	终止 aa	E-value	Score	说明
`XP_057784361.1`	Pfam	`PF00400`	WD40	Repeat	16	50	3.4e-77	252.4	WD domain, G-beta repeat
`XP_057784361.1`	Pfam	`PF25175`	Beta-prop_WDR5	Repeat	19	311	3.3e-142	473.7	WDR5 beta-propeller domain
`XP_057784361.1`	Pfam	`PF00400`	WD40	Repeat	59	95	3.4e-77	252.4	WD domain, G-beta repeat
`XP_057784361.1`	Pfam	`PF12894`	ANAPC4_WD40	Repeat	66	117	4.8e-29	101.1	Anaphase-promoting complex subunit 4 WD40 domain
`XP_057784361.1`	Pfam	`PF23342`	WDR90_beta-prop_4th	Repeat	70	198	6.1e-21	75.5	WDR90, 4th beta-propeller
`XP_057784361.1`	Pfam	`PF23381`	Beta-prop_IFT122_1st	Repeat	70	241	9.3e-82	275.2	IFT122 first beta-propeller
`XP_057784361.1`	Pfam	`PF00400`	WD40	Repeat	99	137	3.4e-77	252.4	WD domain, G-beta repeat
`XP_057784361.1`	Pfam	`PF12894`	ANAPC4_WD40	Repeat	108	160	4.8e-29	101.1	Anaphase-promoting complex subunit 4 WD40 domain
`XP_057784361.1`	Pfam	`PF00400`	WD40	Repeat	141	179	3.4e-77	252.4	WD domain, G-beta repeat
`XP_057784361.1`	Pfam	`PF00400`	WD40	Repeat	184	222	3.4e-77	252.4	WD domain, G-beta repeat
`XP_057784361.1`	Pfam	`PF00400`	WD40	Repeat	226	266	3.4e-77	252.4	WD domain, G-beta repeat
`XP_057784361.1`	Pfam	`PF00400`	WD40	Repeat	272	311	3.4e-77	252.4	WD domain, G-beta repeat

cDNA / CDS / Protein 序列

下载基因组 DNA（仅基因区域）

每个公开基因均提供参考注释对应的转录本序列；蛋白编码基因另提供 CDS 和蛋白序列。非编码 RNA 不适用 CDS 或蛋白下载。真实 accession 的版本后缀予以保留。

cDNA

1 records

下载 cDNA FASTA

XM_057928378.1
TGGAAAGAGGTTAATTTTTAATATTAATACCTGTCTGCAAAAACCCCAACAAAACCCCAAATCCGAAGAAAGAGAAATAGAACAAGAATGGCTTCCACGACGGAGCCAACGGACTCCTATAAACCCTACCGCCTCAAGCACACTCTCTCCGGCCACAAACGCGCCGTCTCCAGCGTCAAATTCTCCGAGGACGGCCGTTTCCTGGCCTCCTGCGCGGCCGACAAGACCGCTCGCACGTACTCCCTCTCCTCCCCCGACAC...

CDS

1 records

下载 CDS FASTA

LOC131001786
ATGGCTTCCACGACGGAGCCAACGGACTCCTATAAACCCTACCGCCTCAAGCACACTCTCTCCGGCCACAAACGCGCCGTCTCCAGCGTCAAATTCTCCGAGGACGGCCGTTTCCTGGCCTCCTGCGCGGCCGACAAGACCGCTCGCACGTACTCCCTCTCCTCCCCCGACACCCCCCACAACGAGTTCCATGGCCACGAAGCCGGCATCTCCGACCTGGCCTTCTCCTCCGACGGCCGCTTCCTCGCCACCGCCTCCGA...

Protein

1 records

下载 Protein FASTA

XP_057784361.1
MASTTEPTDSYKPYRLKHTLSGHKRAVSSVKFSEDGRFLASCAADKTARTYSLSSPDTPHNEFHGHEAGISDLAFSSDGRFLATASDDRTVRLWDVATGSLVKTLTGHTNYVFCLNFNPQSNMLASGSFDETVRIWDVKSGKCLKVLPAHSDPVTAVNFNLDGSMIVSSSYDGLCRIWDASTGHCMKTLIDDEHPPVSFAKFSPNGKFILVGTLDNTLRLWNFSTGKFLKTYTGHVNSKFCISSTFSITNGKYIVSGSED...

上下游序列下载

upstream/downstream 最大各 10000 bp。负链基因会自动反向互补，使最终 FASTA 为转录方向 5′→3′。

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JBrowse

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