Gene Card 基因详情

支持统一新 ID、NCBI Gene ID、GeneID、locus_tag、Transcript ID、Protein ID，以及已人工核对的文献基因名查询。页面会先解析到丹参统一基因，再整合坐标、序列、注释、亚细胞定位、EMS 突变和下载入口。

当前解析结果

`SmilChr08G002585`

染色体: Chr08 坐标: 25183708-25187363 链方向: + 类型: protein_coding

基本信息

统一新 Gene ID	`SmilChr08G002585`
名称	SmilChr08G002585
描述	transcription elongation factor TFIIS
染色体 / SeqID	Chr08 / NC_080394.1
坐标与链方向	25183708 - 25187363 / `+`

ID 对照

NCBI Gene ID	`LOC130997221`
GeneID	`130997221`
locus_tag	`-`
NCBI Name	`LOC130997221`
原始查询	`SmilChr08G002585`

查看完整 ID 对照表

功能注释

来源	GFF basic annotation; NCBI GO GAF; Pfam-A/HMMER; Arabidopsis/Rice homolog
描述	transcription elongation factor TFIIS
产物	transcription elongation factor TFIIS
Arabidopsis	`AT2G38560` (TFIIS) transcript elongation factor IIS [Source:NCBI gene (formerly Entrezgene);Acc:818438] identity=48.2; qcov=1.08; evalue=2.06e-113; confidence=high
Rice	`Os03g0815900` - identity=49.1; qcov=1.05; evalue=9.11e-124; confidence=high
GO	GO:0003676 (nucleic acid binding); GO:0005634 (nucleus); GO:0006351 (DNA-templated transcription); GO:0006368 (transcription elongation by RNA polymerase II); GO:0008270 (zinc ion binding)
KEGG	-
Pfam	PF01096 (Zn_ribbon_TFIIS); PF07500 (TFIIS_M); PF08711 (Med26)
InterPro	-
eggNOG	-
NR	GeneID:130997221

打开注释模块

亚细胞定位 Top 5

Rank	定位位置	中文	Score	Protein ID
1	Nucleus	细胞核	1.00000	`XP_057778456.1`
2	Nucleoplasm	核质	1.00000	`XP_057778456.1`
3	Nuclear body	核内小体	0.40000	`XP_057778456.1`
4	Nucleolar fibrillar center	Nucleolar fibrillar center	0.40000	`XP_057778456.1`
5	Chromosome	染色体	0.20000	`XP_057778456.1`

进入亚细胞定位查询

EMS 诱变突变

下表显示该基因在丹参 EMS 材料中的前 12 个候选突变；完整结果可进入 EMS 突变库继续筛选或下载。

位置	REF	ALT	类型	影响	携带材料数	材料
`Chr8:25184444`	`G`	`A`	EMS_canonical_SNV	CDS_variant	2	B104,B135
`Chr8:25184503`	`G`	`A`	EMS_canonical_SNV	CDS_variant	1	B1
`Chr8:25186209`	`TC`	`T`	1bp_deletion	frameshift_variant	1	B28
`Chr8:25186209`	`TC`	`T`	1bp_deletion	CDS_variant	1	B28
`Chr8:25186212`	`G`	`A`	EMS_canonical_SNV	CDS_variant	1	B28
`Chr8:25186572`	`C`	`T`	EMS_canonical_SNV	CDS_variant	1	C14
`Chr8:25186696`	`C`	`T`	EMS_canonical_SNV	CDS_variant	3	B130,B136,C87
`Chr8:25186786`	`C`	`T`	EMS_canonical_SNV	CDS_variant	1	D11
`Chr8:25186945`	`C`	`T`	EMS_canonical_SNV	CDS_variant	2	C32,C68
`Chr8:25187023`	`C`	`T`	EMS_canonical_SNV	CDS_variant	3	C13,C39,C83

进入 EMS 突变库

预测功能结构域

结构域结果来自 Pfam-A HMM 数据库和 HMMER hmmscan；位置为对应蛋白序列上的氨基酸坐标。

XP_057778456.1

364 aa

182

364

Med26

TFIIS_M

Zn_ribbon_TFIIS

PF08711 Med26 33-81 aa PF07500 TFIIS_M 193-310 aa PF01096 Zn_ribbon_TFIIS 324-362 aa

XP_057778457.1

364 aa

182

364

Med26

TFIIS_M

Zn_ribbon_TFIIS

PF08711 Med26 33-81 aa PF07500 TFIIS_M 193-310 aa PF01096 Zn_ribbon_TFIIS 324-362 aa

XP_057778458.1

364 aa

182

364

Med26

TFIIS_M

Zn_ribbon_TFIIS

PF08711 Med26 33-81 aa PF07500 TFIIS_M 193-310 aa PF01096 Zn_ribbon_TFIIS 324-362 aa

Protein ID	来源	结构域编号	结构域名称	类型	起始 aa	终止 aa	E-value	Score	说明
`XP_057778456.1`	Pfam	`PF08711`	Med26	Domain	33	81	1.5e-12	47.8	TFIIS helical bundle-like domain
`XP_057778456.1`	Pfam	`PF07500`	TFIIS_M	Domain	193	310	4e-32	111.7	Transcription factor S-II (TFIIS), central domain
`XP_057778456.1`	Pfam	`PF01096`	Zn_ribbon_TFIIS	Domain	324	362	3.3e-18	65.9	Transcription factor S-II (TFIIS)
`XP_057778457.1`	Pfam	`PF08711`	Med26	Domain	33	81	1.5e-12	47.8	TFIIS helical bundle-like domain
`XP_057778457.1`	Pfam	`PF07500`	TFIIS_M	Domain	193	310	4e-32	111.7	Transcription factor S-II (TFIIS), central domain
`XP_057778457.1`	Pfam	`PF01096`	Zn_ribbon_TFIIS	Domain	324	362	3.3e-18	65.9	Transcription factor S-II (TFIIS)
`XP_057778458.1`	Pfam	`PF08711`	Med26	Domain	33	81	1.5e-12	47.8	TFIIS helical bundle-like domain
`XP_057778458.1`	Pfam	`PF07500`	TFIIS_M	Domain	193	310	4e-32	111.7	Transcription factor S-II (TFIIS), central domain
`XP_057778458.1`	Pfam	`PF01096`	Zn_ribbon_TFIIS	Domain	324	362	3.3e-18	65.9	Transcription factor S-II (TFIIS)

cDNA / CDS / Protein 序列

下载基因组 DNA（仅基因区域）

每个公开基因均提供参考注释对应的转录本序列；蛋白编码基因另提供 CDS 和蛋白序列。非编码 RNA 不适用 CDS 或蛋白下载。真实 accession 的版本后缀予以保留。

cDNA

3 records

下载 cDNA FASTA

XM_057922473.1
TGGGCATCAATGCATTGCACGCACACAAGGAAGGATTCTTAGCCGTTAGATCGTTGGACCAAACACAGCCGTCTATATATGTATCTTAAAACACAACTCAACGACCTTGTTTTATCTCTCCCCGAAATCCACAAAATAGCGCGCACACAAACACAATACATTATAAGACTTCAGTCGCCAATTACCCAAACTAGGGTTTCGGCTTCGTCGGAAGCCATAGCTGAATGCTGCATTCCTTTGAATAAAGAGAGGAATAATGG...

XM_057922475.1
AAACACAACTCAACGACCTTGTTTTATCTCTCCCCGAAATCCACAAAATAGCGCGCACACAAACACAATACATTATAAGACTTCAGTCGCCAATTACCCAAACTAGGGTTTCGGCTTCGTCGGAAGCCATAGCTGAATGCTGCATTCCTTTGAATAAAGATTTATGGTTTTGAAGATTTCGGAGTATGTAATCAATTGCAAGAATGGATTTTTGTTCGGTCAAATGCTTGTTTATATATTTGTGGAAGCTCTATTTAGGG...

CDS

3 records

下载 CDS FASTA

LOC130997221
ATGGAGAAGGAGCTAAGTGAGCTATTTGAGTCGGTGAAGAGAGCTGCAGATGAGGCTGAGAACTCACCTGGGGAAGAGGATCGATGTCTTGATGAATTAAAGAAGCTCAAGAAGTTCCCTGTTAATTATCAAGTCCTTGTGTCCACACAGGTGGGGAAACGTCTCCGCCAATTGACTAAACATAGAAGTGATAAGATCAAAGCACTGGCTTCTGATGTGGTTGATATTTGGAAAAGCATAATTGTCAAAGAAACAATGAA...

Protein

3 records

下载 Protein FASTA

XP_057778456.1
MEKELSELFESVKRAADEAENSPGEEDRCLDELKKLKKFPVNYQVLVSTQVGKRLRQLTKHRSDKIKALASDVVDIWKSIIVKETMKNKKNGNSENSDSVKTESPRSEANGAKNFQRTNSMKSDQNSPAPKKLKVDNSDKSMKSGSSSSAKIEKVEVQKTKNGAEEVKASPAVRKPQSTPTAPPKLSSLVSCKDPLRDKVREILAEALCKVSGEADADLKDRVDQHDPNRVAVQVESAMFEKWGKSNGPHKFKYRSVMFN...

XP_057778457.1
MEKELSELFESVKRAADEAENSPGEEDRCLDELKKLKKFPVNYQVLVSTQVGKRLRQLTKHRSDKIKALASDVVDIWKSIIVKETMKNKKNGNSENSDSVKTESPRSEANGAKNFQRTNSMKSDQNSPAPKKLKVDNSDKSMKSGSSSSAKIEKVEVQKTKNGAEEVKASPAVRKPQSTPTAPPKLSSLVSCKDPLRDKVREILAEALCKVSGEADADLKDRVDQHDPNRVAVQVESAMFEKWGKSNGPHKFKYRSVMFN...

上下游序列下载

upstream/downstream 最大各 10000 bp。负链基因会自动反向互补，使最终 FASTA 为转录方向 5′→3′。

下载 upstream 下载 downstream 下载 upstream + gene + downstream

JBrowse

跳转到基因组浏览器