Gene Card 基因详情

支持统一新 ID、NCBI Gene ID、GeneID、locus_tag、Transcript ID、Protein ID，以及已人工核对的文献基因名查询。页面会先解析到丹参统一基因，再整合坐标、序列、注释、亚细胞定位、EMS 突变和下载入口。

当前解析结果

`SmilChr08G002610`

染色体: Chr08 坐标: 25465970-25468839 链方向: - 类型: protein_coding

基本信息

统一新 Gene ID	`SmilChr08G002610`
名称	SmilChr08G002610
描述	cell division cycle 20.3, cofactor of APC complex-like
染色体 / SeqID	Chr08 / NC_080394.1
坐标与链方向	25465970 - 25468839 / `-`

ID 对照

NCBI Gene ID	`LOC130997246`
GeneID	`130997246`
locus_tag	`-`
NCBI Name	`LOC130997246`
原始查询	`SmilChr08G002610`

查看完整 ID 对照表

功能注释

来源	GFF basic annotation; NCBI GO GAF; KEGG smil; Pfam-A/HMMER; Arabidopsis/Rice homolog
描述	cell division cycle 20.3, cofactor of APC complex-like
产物	cell division cycle 20.3%2C cofactor of APC complex-like
Arabidopsis	`AT5G27080` (CDC20.3) cell division cycle 20.2, cofactor of APC complex-like protein [Source:NCBI gene (formerly Entrezgene);Acc:832766] identity=43.6; qcov=0.936; evalue=1.23e-111; confidence=medium
Rice	`Os04g0599800` (OsWD40-109) - identity=45.3; qcov=0.92; evalue=3.81e-112; confidence=high
GO	GO:0005515 (protein binding); GO:0005680 (anaphase-promoting complex); GO:0010997 (anaphase-promoting complex binding); GO:0031145 (anaphase-promoting complex-dependent catabolic process); GO:1904668 (positive regulation of ubiquitin protein ligase activity); GO:1905786 (positive regulation of anaphase-promoting complex-dependent catabolic process); GO:1990757 (ubiquitin ligase activator activity)
KEGG	smil04120 (Ubiquitin mediated proteolysis - Salvia miltiorrhiza (redroot sage))
Pfam	PF00400 (WD40); PF08662 (eIF2A); PF12894 (ANAPC4_WD40); PF24807 (WD40_CDC20-Fz)
InterPro	-
eggNOG	-
NR	GeneID:130997246

打开注释模块

亚细胞定位 Top 5

Rank	定位位置	中文	Score	Protein ID
1	Nucleus	细胞核	1.00000	`XP_057778495.1`
2	Cytoplasm	细胞质	0.40000	`XP_057778495.1`
3	Chromosome	染色体	0.00000	`XP_057778495.1`
4	Centromere	着丝粒	0.00000	`XP_057778495.1`
5	Chromatin	染色质	0.00000	`XP_057778495.1`

进入亚细胞定位查询

EMS 诱变突变

下表显示该基因在丹参 EMS 材料中的前 12 个候选突变；完整结果可进入 EMS 突变库继续筛选或下载。

位置	REF	ALT	类型	影响	携带材料数	材料
`Chr8:25466611`	`G`	`A`	EMS_canonical_SNV	CDS_variant	1	B130
`Chr8:25467016`	`G`	`A`	EMS_canonical_SNV	CDS_variant	3	B23,B55,C60
`Chr8:25467066`	`C`	`T`	EMS_canonical_SNV	CDS_variant	1	A18
`Chr8:25467067`	`G`	`A`	EMS_canonical_SNV	CDS_variant	4	A2,A5,B7,B80
`Chr8:25467088`	`C`	`T`	EMS_canonical_SNV	CDS_variant	1	C41
`Chr8:25467110`	`C`	`T`	EMS_canonical_SNV	CDS_variant	1	C82
`Chr8:25467169`	`G`	`A`	EMS_canonical_SNV	CDS_variant	1	C84
`Chr8:25467226`	`C`	`T`	EMS_canonical_SNV	CDS_variant	1	B130
`Chr8:25467575`	`GGA`	`G`	2bp_deletion	frameshift_variant	3	B134,B22,C79
`Chr8:25467575`	`GGA`	`G`	2bp_deletion	CDS_variant	3	B134,B22,C79
`Chr8:25467618`	`C`	`T`	EMS_canonical_SNV	CDS_variant	2	B118,B44
`Chr8:25467817`	`TC`	`T`	1bp_deletion	frameshift_variant	1	C41

进入 EMS 突变库

预测功能结构域

结构域结果来自 Pfam-A HMM 数据库和 HMMER hmmscan；位置为对应蛋白序列上的氨基酸坐标。

XP_057778495.1

451 aa

226

451

WD40_CDC20-Fz

ANAPC4_WD40

eIF2A

WD40

ANAPC4_WD40

WD40

PF24807 WD40_CDC20-Fz 128-423 aa PF12894 ANAPC4_WD40 158-228 aa PF08662 eIF2A 243-362 aa PF00400 WD40 253-288 aa PF12894 ANAPC4_WD40 295-359 aa PF00400 WD40 298-336 aa PF00400 WD40 397-424 aa

Protein ID	来源	结构域编号	结构域名称	类型	起始 aa	终止 aa	E-value	Score	说明
`XP_057778495.1`	Pfam	`PF24807`	WD40_CDC20-Fz	Repeat	128	423	4.9e-110	368.1	CDC20/Fizzy WD40 domain
`XP_057778495.1`	Pfam	`PF12894`	ANAPC4_WD40	Repeat	158	228	3.2e-17	63.3	Anaphase-promoting complex subunit 4 WD40 domain
`XP_057778495.1`	Pfam	`PF08662`	eIF2A	Repeat	243	362	6.9e-08	33.3	Eukaryotic translation initiation factor eIF2A
`XP_057778495.1`	Pfam	`PF00400`	WD40	Repeat	253	288	3.8e-23	81.6	WD domain, G-beta repeat
`XP_057778495.1`	Pfam	`PF12894`	ANAPC4_WD40	Repeat	295	359	3.2e-17	63.3	Anaphase-promoting complex subunit 4 WD40 domain
`XP_057778495.1`	Pfam	`PF00400`	WD40	Repeat	298	336	3.8e-23	81.6	WD domain, G-beta repeat
`XP_057778495.1`	Pfam	`PF00400`	WD40	Repeat	397	424	3.8e-23	81.6	WD domain, G-beta repeat

cDNA / CDS / Protein 序列

下载基因组 DNA（仅基因区域）

每个公开基因均提供参考注释对应的转录本序列；蛋白编码基因另提供 CDS 和蛋白序列。非编码 RNA 不适用 CDS 或蛋白下载。真实 accession 的版本后缀予以保留。

cDNA

1 records

下载 cDNA FASTA

XM_057922512.1
ACAGAAAAATGAAAAAGAAAAGAAAAGGAAGGCTTTAACCAGAAAATCCAACCCAAAACACAAAATGTCTTTTGGCGCGAAATAGCAGTAGACGTTAGTTAGTTACATCACAATTCCCCCTTCTTAATCTGGAAATGAATCTCTGTAATTGATCAATATTCCGTAAAACTTTCGGAACAGTAAAGAGGAGCAACAATGGAGGATGAGAGGGATTGGAGACTCGCCTCCGATTGGTACTCTCCAACTCGCCTCCACGACAG...

CDS

1 records

下载 CDS FASTA

LOC130997246
ATGGAGGATGAGAGGGATTGGAGACTCGCCTCCGATTGGTACTCTCCAACTCGCCTCCACGACAGTCCCGTCAAATATGATTTTCCGGGCGATAGGTTTATTCCAAATCGGAGCCTGATGGATCTCGATCAAGCCCACGGTGCGCTGACCAACAGGGTCGTCCAACGCCCCACACATACCAAATCCAGTATTGAATATAGGAAGTCTTTGAGCAATCTGACCTTGAATGCTGATGGTAGGCCATTTCAGATGCTTGTTTT...

Protein

1 records

下载 Protein FASTA

XP_057778495.1
MEDERDWRLASDWYSPTRLHDSPVKYDFPGDRFIPNRSLMDLDQAHGALTNRVVQRPTHTKSSIEYRKSLSNLTLNADGRPFQMLVFRGSPKSSRKPNPMVDETRRSNSEYPTCIPLRRFPKGESKILDAPGISHDYYLNIVDWGKENILAAALDRRLYLWDANTGKVDLLSEVKEDDYLASVSWSENGRVVAAGNSCSTVHLYDVETLHLVRLLEGHRGRVGSIAWNGHTVACGTSSGDITNHDVRVRNSQVCRVKVHK...

上下游序列下载

upstream/downstream 最大各 10000 bp。负链基因会自动反向互补，使最终 FASTA 为转录方向 5′→3′。

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