Gene Card 基因详情

支持统一新 ID、NCBI Gene ID、GeneID、locus_tag、Transcript ID、Protein ID，以及已人工核对的文献基因名查询。页面会先解析到丹参统一基因，再整合坐标、序列、注释、亚细胞定位、EMS 突变和下载入口。

当前解析结果

`SmilChr08G003353`

染色体: Chr08 坐标: 34931898-34938234 链方向: - 类型: protein_coding

基本信息

统一新 Gene ID	`SmilChr08G003353`
名称	SmilChr08G003353
描述	pyruvate kinase 1, cytosolic-like
染色体 / SeqID	Chr08 / NC_080394.1
坐标与链方向	34931898 - 34938234 / `-`

ID 对照

NCBI Gene ID	`LOC130997909`
GeneID	`130997909`
locus_tag	`-`
NCBI Name	`LOC130997909`
原始查询	`SmilChr08G003353`

查看完整 ID 对照表

功能注释

来源	GFF basic annotation; NCBI GO GAF; KEGG smil; Pfam-A/HMMER; Arabidopsis/Rice homolog
描述	pyruvate kinase 1, cytosolic-like
产物	pyruvate kinase 1%2C cytosolic-like
Arabidopsis	`AT3G52990` (AT3G52990) Pyruvate kinase family protein [Source:NCBI gene (formerly Entrezgene);Acc:824465] identity=86.3; qcov=1; evalue=0; confidence=high
Rice	`Os11g0148500` (OsPK1) - identity=87.7; qcov=1; evalue=0; confidence=high
GO	GO:0000287 (magnesium ion binding); GO:0004743 (pyruvate kinase activity); GO:0005737 (cytoplasm); GO:0006096 (glycolytic process); GO:0030955 (potassium ion binding)
KEGG	smil00010 (Glycolysis / Gluconeogenesis - Salvia miltiorrhiza (redroot sage)); smil00620 (Pyruvate metabolism - Salvia miltiorrhiza (redroot sage)); smil01100 (Metabolic pathways - Salvia miltiorrhiza (redroot sage)); smil01110 (Biosynthesis of secondary metabolites - Salvia miltiorrhiza (redroot sage)); smil01200 (Carbon metabolism - Salvia miltiorrhiza (redroot sage)); smil01230 (Biosynthesis of amino acids - Salvia miltiorrhiza (redroot sage))
Pfam	PF00224 (PK); PF02887 (PK_C)
InterPro	-
eggNOG	-
NR	GeneID:130997909

打开注释模块

亚细胞定位 Top 5

Rank	定位位置	中文	Score	Protein ID
1	Cytoplasm	细胞质	1.00000	`XP_057779316.1`
2	Cytosol	细胞质基质	1.00000	`XP_057779316.1`
3	Nucleus	细胞核	0.40000	`XP_057779316.1`
4	Nucleoplasm	核质	0.40000	`XP_057779316.1`
5	Chromosome	染色体	0.00000	`XP_057779316.1`

进入亚细胞定位查询

EMS 诱变突变

下表显示该基因在丹参 EMS 材料中的前 12 个候选突变；完整结果可进入 EMS 突变库继续筛选或下载。

位置	REF	ALT	类型	影响	携带材料数	材料
`Chr8:34932671`	`C`	`T`	EMS_canonical_SNV	CDS_variant	1	B55
`Chr8:34932738`	`G`	`A`	EMS_canonical_SNV	CDS_variant	3	B13,C8,D7
`Chr8:34932750`	`C`	`T`	EMS_canonical_SNV	CDS_variant	1	C14
`Chr8:34932898`	`C`	`T`	EMS_canonical_SNV	CDS_variant	5	A19,B137,B87,C1,C50
`Chr8:34933132`	`T`	`TA`	1bp_insertion	frameshift_variant	4	A22,B58,B64,C84
`Chr8:34933132`	`T`	`TA`	1bp_insertion	CDS_variant	4	A22,B58,B64,C84
`Chr8:34933133`	`C`	`CT`	1bp_insertion	frameshift_variant	4	A22,B58,B64,C84
`Chr8:34933133`	`C`	`CT`	1bp_insertion	CDS_variant	4	A22,B58,B64,C84
`Chr8:34935366`	`C`	`T`	EMS_canonical_SNV	CDS_variant	1	B104
`Chr8:34936118`	`CAA`	`C`	2bp_deletion	frameshift_variant	1	C52
`Chr8:34936118`	`CAA`	`C`	2bp_deletion	CDS_variant	1	C52
`Chr8:34936121`	`T`	`TGG`	2bp_insertion	frameshift_variant	1	C52

进入 EMS 突变库

预测功能结构域

结构域结果来自 Pfam-A HMM 数据库和 HMMER hmmscan；位置为对应蛋白序列上的氨基酸坐标。

XP_057779316.1

527 aa

264

527

PK_C

PF00224 PK 30-360 aa PF02887 PK_C 395-515 aa

Protein ID	来源	结构域编号	结构域名称	类型	起始 aa	终止 aa	E-value	Score	说明
`XP_057779316.1`	Pfam	`PF00224`	PK	Domain	30	360	1e-87	295.0	Pyruvate kinase, barrel domain
`XP_057779316.1`	Pfam	`PF02887`	PK_C	Domain	395	515	5.4e-24	85.2	Pyruvate kinase, alpha/beta domain

cDNA / CDS / Protein 序列

下载基因组 DNA（仅基因区域）

每个公开基因均提供参考注释对应的转录本序列；蛋白编码基因另提供 CDS 和蛋白序列。非编码 RNA 不适用 CDS 或蛋白下载。真实 accession 的版本后缀予以保留。

cDNA

2 records

下载 cDNA FASTA

XR_009093251.1
AAAACAGGAAATTGATGAAAGAATACTAGTAGTGGTATCGTACTTTTTTTTTCTCTGCATAGACCAAACCGTTCAATTTTTCTTCTTCGTCTTCCAGTGTAATCAATTATTCGCCGGGAATTTCAATTTCGAAAAAGATGCATTCGAATCACCTGCTGCTCGAGGAGCCAATCCGCATGGCCTCCATTCTGGAGCCATCCAAAGCGGGTTTCTTCCCCGCAATGGCGAAGATTGTGGGGACGTTGGGCTCGCGCTCACGA...

XM_057923333.1
GTACTTGAGAGAGAAAAAAAAAATTAAATAAAACACAGAAGTATTAACTAAAACAGGAAATTGATGAAAGAATACTAGTAGTGGTATCGTACTTTTTTTTTCTCTGCATAGACCAAACCGTTCAATTTTTCTTCTTCGTCTTCCAGTGTAATCAATTATTCGCCGGGAATTTCAATTTCGAAAAAGATGCATTCGAATCACCTGCTGCTCGAGGAGCCAATCCGCATGGCCTCCATTCTGGAGCCATCCAAAGCGGGTTT...

CDS

1 records

下载 CDS FASTA

LOC130997909
ATGCATTCGAATCACCTGCTGCTCGAGGAGCCAATCCGCATGGCCTCCATTCTGGAGCCATCCAAAGCGGGTTTCTTCCCCGCAATGGCGAAGATTGTGGGGACGTTGGGCTCGCGCTCACGAACCGTCGATGTTATTTCTGCTTGTCTTAAAGCTGGAATGACTGTGGCGAGATTTGATTTTTCGTTGGGTGATGCCGAGTATCATCAGGGAACTCTAGAAAATTTGAAGACTGCGATTAAGAGCACTAAGAAACTCTG...

Protein

1 records

下载 Protein FASTA

XP_057779316.1
MHSNHLLLEEPIRMASILEPSKAGFFPAMAKIVGTLGSRSRTVDVISACLKAGMTVARFDFSLGDAEYHQGTLENLKTAIKSTKKLCAVMLDTVGPELQVVNKAEKAITLKADENVILTPDQGQEASNEILPINFAGLAKAVKKGDTIFIGQYLFTGSESTSVWLEVNEVKGNDVVCAVKNSATLAGSLFTLHASQIRIELPTLSDKDKQFISSWGVQNKIDFLSLSYTRHAEDVREARDFLSKLGDLSQTQIFAKIENV...

上下游序列下载

upstream/downstream 最大各 10000 bp。负链基因会自动反向互补，使最终 FASTA 为转录方向 5′→3′。

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JBrowse

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